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1. 再颁专利

USRE37852E1 Blood pressure monitoring system 有权
标题翻译：血压监测系统
公开(公告)号：USRE37852E1
公开(公告)日：2002-09-17
申请号：US09172024
申请日：1998-10-14
申请人： Shigeru Aso , Hiroshi Sakata , Yoshihiro Sugo , Hidehiro Hosaka
发明人： Shigeru Aso , Hiroshi Sakata , Yoshihiro Sugo , Hidehiro Hosaka
IPC分类号： A61B500
CPC分类号： A61B5/02255 , A61B5/0285
摘要： A blood pressure monitoring system includes a blood pressure measurement device for measuring blood pressure using a cuff, a memory for storing an externally inputted pulse wave propagation time fluctuation threshold, a time interval detection reference point detection section for detecting a time interval detection reference point in a pulse wave on the side of aortae of a living organism, a pulse wave detection section for detecting a pulse wave on the side of peripheral blood vessels appearing with a time lag with respect to the pulse wave on the side of aortae, a pulse wave propagation time measurement section for measuring a pulse wave propagation time based on respective detected outputs from the time interval detection reference point detection section and the pulse wave detection section, an operation device for calculating a pulse wave propagation fluctuation from two measured pulse wave propagation times, a judgment device for judging whether or not the calculated pulse wave propagation time fluctuation exceeds the pulse wave propagation time fluctuation threshold read from the memory, and a control device for controlling the blood pressure measurement device based on an output of the judgment device so that the blood pressure of a subject is measured using the cuff.
摘要翻译：一种血压监视系统，包括使用袖带测量血压的血压测量装置，用于存储外部输入的脉搏波传播时间波动阈值的存储器，用于检测时间间隔检测基准点的时间间隔检测基准点检测部生物体的主动脉侧的脉波，脉波检测部，用于检测相对于主动脉侧的脉搏波出现的与时间差相关的外周血管侧的脉波，脉波传播时间测量部分，用于基于来自时间间隔检测参考点检测部分和脉搏波检测部分的各个检测到的输出来测量脉搏波传播时间;操作装置，用于从两个测量的脉搏波传播时间计算脉搏波传播波动，用于判断计算出的脉搏波的判断装置传播时间波动超过从存储器读取的脉搏波传播时间波动阈值，以及控制装置，用于根据判断装置的输出控制血压测量装置，从而使用袖带测量被检者的血压。

2. 发明授权

US5564427A Blood pressure monitoring system 失效
公开(公告)号：US5564427A
公开(公告)日：1996-10-15
申请号：US413850
申请日：1995-03-30
申请人： Shigeru Aso , Hiroshi Sakata , Yoshihiro Sugo , Hidehiro Hosaka
发明人： Shigeru Aso , Hiroshi Sakata , Yoshihiro Sugo , Hidehiro Hosaka
IPC分类号： A61B5/022 , A61B5/0225 , A61B5/0285 , A61B5/00
CPC分类号： A61B5/02255 , A61B5/0285
摘要： A blood pressure monitoring system includes a blood pressure measurement device for measuring blood pressure using a cuff, a memory for storing an externally inputted pulse wave propagation time fluctuation threshold, a time interval detection reference point detection section for detecting a time interval detection reference point in a pulse wave on the side of aortae of a living organism, a pulse wave detection section for detecting a pulse wave on the side of peripheral blood vessels appearing with a time lag with respect to the pulse wave on the side of aortae, a pulse wave propagation time measurement section for measuring a pulse wave propagation time based on respective detected outputs from the time interval detection reference point detection section and the pulse wave detection section, an operation device for calculating a pulse wave propagation fluctuation from two measured pulse wave propagation times, a judgment device for judging whether or not the calculated pulse wave propagation time fluctuation exceeds the pulse wave propagation time fluctuation threshold read from the memory, and a control device for controlling the blood pressure measurement device based on an output of the judgment device so that the blood pressure of a subject is measured using the cuff.

3. 发明授权

US5649543A Pulse-wave propagation time basis blood pressure monitor 失效
标题翻译：脉搏波传播时间基准血压监测仪
公开(公告)号：US5649543A
公开(公告)日：1997-07-22
申请号：US466746
申请日：1995-06-06
申请人： Hidehiro Hosaka , Hiroshi Sakata , Yoshihiro Sugo , Takeshi Sohma , Hiromitsu Kasuya
发明人： Hidehiro Hosaka , Hiroshi Sakata , Yoshihiro Sugo , Takeshi Sohma , Hiromitsu Kasuya
IPC分类号： A61B5/0205 , A61B5/022 , A61B5/0225 , A61B5/0285 , A61B5/00
CPC分类号： A61B5/0285 , A61B5/02255
摘要： A pulse-wave propagation time basis blood pressure monitor includes a memory for storing an equation describing the relationship between the pulse wave propagation time and the parameter .alpha., input means for entering the blood pressure value for calibration, a time-interval detect reference point detecting means for detecting a reference point for detecting the time interval of a pulse wave in the aorta of a subject; pulse wave detecting means for detecting a pulse wave which appears in the peripheral blood vessel after it appears in the aorta; pulse-wave propagation time measuring section for measuring a pulse wave propagation time from the output signals of the time-interval detect reference point detecting means and the pulse wave detecting means, first computing means for determining the parameter .alpha. proper to the subject on the basis of the general equation stored in the memory by using the pulse wave propagation time for calibration gathered from the subject, second computing means for determining the parameter .beta. to be added in computing a blood pressure value by using the pulse wave propagation time, by using the blood pressure value inputted for calibration, the pulse wave propagation time measured for calibration, and the parameter .alpha. determined by the first computing means, third computing means for computing a blood pressure value by using the measured pulse wave propagation time, and the parameters .alpha. and .beta., and measured data output means for outputting data of the computed blood pressure value.
摘要翻译：脉搏波传播时间基准血压监视器包括用于存储描述脉搏波传播时间和参数α之间的关系的方程式的存储器，用于输入用于校准的血压值的输入装置，时间间隔检测参考点检测用于检测用于检测被检体的主动脉中的脉搏波的时间间隔的参考点的装置; 脉波检测装置，用于检测外周血管出现在主动脉中后出现的脉搏波; 用于根据时间间隔检测基准点检测装置和脉搏波检测装置的输出信号测量脉搏波传播时间的脉波传播时间测量部分，第一计算装置，用于在此基础上确定对象的参数α 通过使用从对象收集的校准的脉搏波传播时间存储在存储器中的一般方程式的第二计算装置，用于通过使用脉波传播时间来确定计算血压值时要添加的参数β的第二计算装置，用于校准输入的血压值，用于校准的脉搏波传播时间和由第一计算装置确定的参数α，第三计算装置，用于通过使用测量的脉搏波传播时间计算血压值，以及参数α和 β和用于输出计算出的血压值的数据的测量数据输出装置。

4. 发明授权

US6083171A Blood pressure monitoring apparatus 失效
标题翻译：血压监测仪
公开(公告)号：US6083171A
公开(公告)日：2000-07-04
申请号：US742750
申请日：1996-11-01
申请人： Kohei Ono , Hiromitsu Kasuya , Yoshihiro Sugo , Takeshi Sohma , Hidehiro Hosaka
发明人： Kohei Ono , Hiromitsu Kasuya , Yoshihiro Sugo , Takeshi Sohma , Hidehiro Hosaka
IPC分类号： A61B5/022 , A61B5/0285 , A61B5/00
CPC分类号： A61B5/022 , A61B5/0285
摘要： A pulse wave propagation time is counted constantly. Not only it is judged whether or not a pulse wave propagation time change .DELTA.T exceeds a pulse wave propagation time change threshold .DELTA.Ts, but also it is judged whether or not cardiovascular dynamic changes .DELTA.HR, r.sub.1, r.sub.2 exceed thresholds thereof .DELTA.HRs, r.sub.1 s, r.sub.2 s, whereby a sudden turn for the worse in the blood pressure fluctuation of a subject is monitored. If any one of the changes exceeds the threshold thereof, a blood pressure measurement using a cuff 2 is made on the subject.
摘要翻译：不断对脉搏波传播时间进行计数。不仅判断脉波传播时间变化DELTA T是否超过脉波传播时间变化阈值DELTA Ts，而且判断心血管动态变化DELTA HR，r1，r2是否超过阈值DELTA HR， r1s，r2s，从而监测受试者的血压波动的突然转动。如果任何一个变化超过其阈值，则对被检体进行使用袖带2的血压测量。

5. 发明授权

US5603329A Multi-functional blood pressure monitor 失效
标题翻译：多功能血压计
公开(公告)号：US5603329A
公开(公告)日：1997-02-18
申请号：US492938
申请日：1995-06-21
申请人： Hidehiro Hosaka , Takashi Nakaya , Yoshihiro Sugo , Hiromitsu Kasuya , Rie Tanaka
发明人： Hidehiro Hosaka , Takashi Nakaya , Yoshihiro Sugo , Hiromitsu Kasuya , Rie Tanaka
IPC分类号： A61B5/0225 , A61B5/00
CPC分类号： A61B5/02125 , A61B5/02255
摘要： The multi-functional blood pressure monitor includes input unit for entering a value of blood pressure for calibration; unit for detecting a time interval detection reference point on an aortic pulse wave, unit for detecting a peripheral blood pulse wave as it appears later than the aortic pulse wave, unit (CPU) for measuring the pulse wave propagation time on the basis of the detection outputs from the unit for detecting a time interval detection reference point and the unit for detecting a peripheral blood pulse wave, first computing unit (CPU) for computing the values of parameters .alpha. and .beta. using the two values of blood pressure that have been entered for calibration and the two pulse wave propagation times that have been measured for calibration, second computing unit (CPU) for computing blood pressure from a measured pulse wave propagation time and the values of parameters .alpha. and .beta., and display for presenting both the computed blood pressure and the value of parameter .alpha. which serves as an index for arteriosclerosis.
摘要翻译：多功能血压计包括用于输入用于校准的血压值的输入单元; 用于检测主动脉脉搏波上的时间间隔检测基准点的单元，用于检测比主动脉脉波更迟的外周血脉波的单元，用于基于检测来测量脉搏波传播时间的单位（CPU）用于检测时间间隔检测参考点的单元的输出和用于检测外周血脉搏波的单元的第一计算单元（CPU），用于使用输入的两个血压值计算参数α和β的值校准和测量的两个脉搏波传播时间，用于从测量的脉搏波传播时间计算血压的第二计算单元（CPU）和参数α和β的值，以及显示用于呈现计算出的血压以及作为动脉硬化指标的参数α的值。

6. 发明授权

US6011989A Patient monitoring apparatus 有权
标题翻译：病人监护仪
公开(公告)号：US6011989A
公开(公告)日：2000-01-04
申请号：US129213
申请日：1998-08-05
申请人： Yoshihiro Sugo , Takeshi Sohma , Rie Tanaka , Wenxi Chen , Shigeru Aso , Ryoichi Ochiai
发明人： Yoshihiro Sugo , Takeshi Sohma , Rie Tanaka , Wenxi Chen , Shigeru Aso , Ryoichi Ochiai
IPC分类号： A61B5/00 , A61B5/0205 , A61B5/0468 , A61B5/0472 , A61B5/02
CPC分类号： A61B5/0468 , A61B5/0205 , A61B5/1455
摘要： An electrocardiogram signal derived from electrocardiogram measuring means 1 and a pulse signal derived from pulse-wave measuring means 2 are applied to a CPU 30. The CPU 30 processes the cardiogram signal to detect a QRS wave signal, and processes the pulse signal to detect the amplitude of the pulse signal. The CPU 30 judges whether or not the QRS wave is caused by a ventricular premature contraction. If two QRS waves, not caused by ventricular premature contraction, occurs successively, and the CPU 30 judges if A0.times.k>A1. The CPU 30 judges that a supraventricular extrasystole is occurred. Here, A0 is an amplitude of the first QSR wave; A1 is an amplitude of the second QSR wave; and k is a preset value, 0
摘要翻译：将来自心电图测量装置1的心电图信号和从脉搏波测量装置2导出的脉冲信号施加到CPU 30.CPU30处理心电图信号以检测QRS波信号，并处理脉冲信号以检测脉冲信号的幅度。 CPU30判断QRS波是否由心室过早收缩引起。如果不是由心室过早收缩引起的两个QRS波连续发生，并且CPU 30判断A0xk> A1。 CPU30判断出发生室上性收缩期。这里，A0是第一QSR波的振幅; A1是第二个QSR波的振幅; k是0

7. 发明授权

US6049731A Patient monitoring apparatus 失效
标题翻译：病人监护仪
公开(公告)号：US6049731A
公开(公告)日：2000-04-11
申请号：US136964
申请日：1998-08-20
申请人： Ryoichi Ochiai , Yoshihiro Sugo , Takeshi Sohma , Rie Tanaka , Wenxi Chen
发明人： Ryoichi Ochiai , Yoshihiro Sugo , Takeshi Sohma , Rie Tanaka , Wenxi Chen
IPC分类号： A61B5/00 , A61B5/022 , A61B5/0402 , A61B5/0452
CPC分类号： A61B5/0452 , A61B5/022
摘要： A pacing-pulse detecting circuit 3 detects pacing pulses from an electrocardiogram signal led from an electrocardiogram electrode 1. A mode-status judging means 21 judges a mode status, a pacing mode or a nonpacing mode, on the basis of the pacing pulse detected. The detect result is transmitted to a CPU 5. The CPU causes a display device 10 to display the result. An operator sees the display and operates a key 22, and gives an instruction to start a blood pressure measurement to the CPU 5. The CPU 5 drives a pump 13 and an exhaust valve 14 to supply and discharge air to and from a cuff 11, and measures a blood pressure by use of pressure data led from a pressure sensor 15.
摘要翻译：起搏脉冲检测电路3根据从心电图电极1引出的心电图信号检测起搏脉冲。模式状态判断装置21基于检测到的起搏脉冲来判断模式状态，起搏模式或非起搏模式。检测结果被发送到CPU 5.CPU使显示装置10显示结果。操作者看到显示器并操作键22，并给出了对CPU 5进行血压测量的指令.CPU5驱动泵13和排气阀14以向袖口11供给和排出空气，并且通过使用从压力传感器15引导的压力数据来测量血压。

8. 发明授权

US5876348A Blood pressure monitoring apparatus 失效
标题翻译：血压监测仪
公开(公告)号：US5876348A
公开(公告)日：1999-03-02
申请号：US993562
申请日：1997-12-18
申请人： Yoshihiro Sugo , Takeshi Sohma , Hiromitsu Kasuya , Rie Tanaka
发明人： Yoshihiro Sugo , Takeshi Sohma , Hiromitsu Kasuya , Rie Tanaka
IPC分类号： A61B5/022 , A61B5/0245 , A61B5/0285 , A61B5/0456 , A61B5/02
CPC分类号： A61B5/02125 , A61B5/022 , A61B5/0285 , A61B5/0456
摘要： During a noninvasive blood pressure measurement using a cuff 2, a pulse wave propagation time T1 from the appearance of the peak value of an R wave in an electrocardiogram (ECG) waveform to the appearance of the bottom value of a pulse wave is counted, and a blood pressure value BP1 is calculated from a count result T1 and parameters .alpha., .beta. specific to a subject obtained during a pulse wave propagation time calibration. Then, the absolute value of a difference between the blood pressure value BP1 and a blood pressure value NIBP1 obtained by the noninvasive blood pressure measurement using the cuff 2 is calculated, and it is indeed whether or not the calculated absolute value is within a predetermined threshold.sub.-- BP. If the absolute value is judged to exceed the threshold.sub.-- BP, then blood pressure is measured again noninvasively using the cuff 2, and a blood pressure value NIBP1'obtained from such repeated measurement is displayed on a display 22.
摘要翻译：在使用袖带2的无创血压测定中，计数从心电图（ECG）波形中的R波的峰值出现到脉搏波的底部值的出现的脉搏波传播时间T1，根据计数结果T1和在脉搏波传播时间校准期间获得的对象特有的参数α，β计算血压值BP1。然后，计算通过使用袖带2的无创血压测定得到的血压值BP1与血压值NIBP1之差的绝对值，实际上是否计算出的绝对值在规定的阈值以内 -BP。如果绝对值被判断为超过阈值-BP，则使用袖带2再次非侵入性地测量血压，并且在显示器22上显示从这种重复测量获得的血压值NIBP1。

9. 发明授权

US09433361B2 Biological information monitor 有权
标题翻译：生物信息监测
公开(公告)号：US09433361B2
公开(公告)日：2016-09-06
申请号：US12872099
申请日：2010-08-31
申请人： Mitsushi Hyogo , Teiji Ukawa , Yoshihiro Sugo , Hiroko Hagiwara
发明人： Mitsushi Hyogo , Teiji Ukawa , Yoshihiro Sugo , Hiroko Hagiwara
IPC分类号： A61B5/02 , A61B5/0225 , A61B5/021 , A61B5/022
CPC分类号： A61B5/0225 , A61B5/02125 , A61B5/02225
摘要： A biological information monitor includes: a first measuring unit which measures a pulse wave propagation time of a patient; a second measuring unit which measures a blood pressure of the patient; a calculating unit which calculates an estimated blood pressure value of the patient based on the pulse wave propagation time of the patient; a setting unit which sets a threshold; and a determining unit which compares the estimated blood pressure value with the threshold. The second measuring unit is activated to measure the blood pressure of the patient at least one of at time intervals and at a time when an operator operates the second measuring unit, and the second measuring unit is activated to measure the blood pressure of the patient by the determining unit based on the comparison result.
摘要翻译：生物信息监视器包括：测量患者的脉搏波传播时间的第一测量单元; 测量患者的血压的第二测量单元; 计算单元，其基于患者的脉搏波传播时间计算患者的估计血压值; 设定单元，设定阈值; 以及确定单元，其将估计的血压值与阈值进行比较。第二测量单元被激活以在时间间隔和操作者操作第二测量单元时的时间间隔中的至少一个被测量患者的血压，并且第二测量单元被激活以通过以下步骤来测量患者的血压所述确定单元基于所述比较结果。

10. 发明授权

US07402138B2 Method and apparatus for measuring blood volume, and vital sign monitor using the same 有权
标题翻译：用于测量血容量的方法和装置，以及使用其的生命体征监测器
公开(公告)号：US07402138B2
公开(公告)日：2008-07-22
申请号：US11094228
申请日：2005-03-31
申请人： Yoshihiro Sugo , Takeshi Akiyama , Keisuke Uchida , Sunao Takeda
发明人： Yoshihiro Sugo , Takeshi Akiyama , Keisuke Uchida , Sunao Takeda
IPC分类号： A61B5/02
CPC分类号： A61B5/029 , A61B5/0245 , A61B5/0285
摘要： A first member is adapted to measure an electrocardiogram of a patient. A second member is adapted to measure a peripheral pulse wave of the patient. A first calculator calculates a pulse wave propagation time (PWTT) and a heart rate (HR) of the patient based on the electrocardiogram and the peripheral pulse wave. A second calculator calculates a cardiac output (CO) of the patient with an equation of CO=(αK·PWTT+βK)·HR, where α, β and K are coefficients inherent to the patient.
摘要翻译：第一构件适于测量患者的心电图。第二构件适于测量患者的外周脉搏波。第一计算器基于心电图和外周脉搏波计算患者的脉搏波传播时间（PWTT）和心率（HR）。第二计算器用CO =（αK.PWTT+βK）·HR等式计算患者的心输出量（CO），其中α，β和K是患者固有的系数。

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