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    • 3. 发明申请
    • PIEZOELECTRIC SENSOR AND SENSING INSTRUMENT
    • 压电传感器和感应仪器
    • US20110064615A1
    • 2011-03-17
    • US12736822
    • 2009-03-02
    • Shigenori WatanabeTakeru MutohMitsuaki Koyama
    • Shigenori WatanabeTakeru MutohMitsuaki Koyama
    • G01N30/00
    • G01N5/02G01N1/405G01N29/022G01N29/2443G01N2291/02466
    • An object of the present invention is to improve detecting ability of a piezoelectric sensor.The present invention, in a piezoelectric sensor having electrodes that are each made of a gold layer formed on one surface side and the other surface side of a piezoelectric piece via adhesive layers by sputtering respectively, and having an adsorption layer that is composed of an antibody provided on a front surface of the electrode on the one surface side, and having the electrode on the other surface side provided to face an airtight space, and detecting an antigen adsorbed to the antibody in accordance with a change in an oscillation frequency of the piezoelectric piece, includes: conductive paths connecting the electrodes to an oscillator circuit; and a conductive adhesive provided over the electrodes and the conductive paths in order to fix the electrodes to the conductive paths and having a binder cure in a state where a conductive filler is joined to the gold layer, and a thickness of the gold layer is set to be equal to or more than 3000 Å.
    • 本发明的目的在于提高压电传感器的检测能力。 本发明涉及一种压电传感器,其具有分别通过溅射形成在压电片的一个表面侧的金层和通过溅射的粘合层形成的电极的电极,并且具有由抗体构成的吸附层 设置在一个表面侧的电极的前表面上,并且将另一个表面侧的电极设置为面对气密空间,并且根据压电体的振荡频率的变化来检测吸附于抗体的抗原 包括:将电极连接到振荡器电路的导电路径; 以及设置在电极和导电路径上的导电粘合剂,以便将电极固定到导电路径上并且在导电填料与金层接合的状态下具有粘合剂固化,并且设置金层的厚度 等于或大于3000Å​​。
    • 5. 发明申请
    • Sensing device
    • 感应装置
    • US20100329932A1
    • 2010-12-30
    • US12803220
    • 2010-06-22
    • Tomoya YoritaShunichi WakamatsuShigenori WatanabeTakeru Mutoh
    • Tomoya YoritaShunichi WakamatsuShigenori WatanabeTakeru Mutoh
    • G01N27/00
    • G01N29/222G01N29/022G01N29/036G01N2291/0255G01N2291/0256
    • To provide a sensing device that measures a substance to be sensed while letting a sample solution flow and has improved accuracy in detecting the substance to be sensed. The sensing device includes: a channel forming member 50 including an opposed surface opposed to an oscillation area on one surface side of a piezoelectric sensor via a gap to form a reaction channel in an area facing the one surface side; a liquid supply channel through which a liquid is supplied to the reaction channel and a liquid discharge channel through which a liquid is discharged from the reaction channel; oscillator circuits 30a, 30b oscillating the quartz-crystal piece; and a frequency measuring part 81 measuring oscillation frequencies of the oscillator circuits 30a, 30b, wherein a height of the reaction channel facing the oscillation area on the one surface side of the quartz-crystal sensor is 0.2 mm or less.
    • 提供一种感测装置,其在使样品溶液流动的同时测量待检测物质,并且在检测待检测物质时具有提高的准确度。 感测装置包括:通道形成构件50,其包括与压电传感器的一个表面侧上的振荡区域相对的相对表面,该相对表面经由间隙在形成面向一个表面侧的区域中形成反应通道; 将液体通过其供应到反应通道的液体供应通道和液体从反应通道排出的液体排出通道; 振荡电路30a,30b振荡石英晶片; 以及测量振荡电路30a,30b的振荡频率的频率测量部分81,其中面对石英晶体传感器的一个表面侧的振荡区域的反应通道的高度为0.2mm或更小。
    • 6. 发明申请
    • Sensing device
    • 感应装置
    • US20100329928A1
    • 2010-12-30
    • US12803228
    • 2010-06-22
    • Tomoya YoritaShunichi WakamatsuShigenori WatanabeTakeru Mutoh
    • Tomoya YoritaShunichi WakamatsuShigenori WatanabeTakeru Mutoh
    • G01N33/00
    • G01N15/00Y10T436/11Y10T436/25375
    • To provide a sensing device using a piezoelectric sensor having an oscillation area for detection and an oscillation area for reference and capable of achieving a high measurement sensitivity by improving shapes of excitation electrodes. On a quartz-crystal piece 20a, there are provided strip-shaped left side area and right side area which are formed symmetrically to be separated from each other into left and right with respect to a center of a circle 53 being a contour of a planar shape of a reaction channel 52 and extend in a longitudinal direction in a parallel manner. Each of the areas is set to have a size in which both corner portions 100 on the left side of the left side area and both corner portions 100 on the right side of the right side area protrude to the outside of the circle 53, the corner portions 100 that protrude to the outside are cut to make the left side area and the right side area position inside of the circle 53, and an excitation electrode 21a for measurement and an excitation electrode 21b for reference are respectively formed on the right side area and the left side area.
    • 为了提供使用具有用于检测的振荡区域和用于参考的振荡区域的压电传感器的感测装置,并且能够通过改善激励电极的形状来实现高测量灵敏度。 在石英片20a上,设有条形左侧区域和右侧区域,它们对称地形成为相对于圆53的中心彼此分离的左侧和右侧,该中心是平面的轮廓 反应通道52的形状并且以纵向方向平行地延伸。 每个区域被设定为具有左侧区域左侧的两个角部100和右侧区域右侧的两个角部100向圆53的外侧突出的尺寸, 将向外侧突出的部分100切割成在圆53内部的左侧区域和右侧区域位置,并且在右侧区域分别形成用于测量的激励电极21a和用于参考的激励电极21b, 左侧区域。
    • 9. 发明授权
    • Sensing device
    • 感应装置
    • US08377380B2
    • 2013-02-19
    • US12803228
    • 2010-06-22
    • Tomoya YoritaShunichi WakamatsuShigenori WatanabeTakeru Mutoh
    • Tomoya YoritaShunichi WakamatsuShigenori WatanabeTakeru Mutoh
    • G01N27/00
    • G01N15/00Y10T436/11Y10T436/25375
    • To provide a sensing device using a piezoelectric sensor having an oscillation area for detection and an oscillation area for reference and capable of achieving a high measurement sensitivity by improving shapes of excitation electrodes. On a quartz-crystal piece 20a, there are provided strip-shaped left side area and right side area which are formed symmetrically to be separated from each other into left and right with respect to a center of a circle 53 being a contour of a planar shape of a reaction channel 52 and extend in a longitudinal direction in a parallel manner. Each of the areas is set to have a size in which both corner portions 100 on the left side of the left side area and both corner portions 100 on the right side of the right side area protrude to the outside of the circle 53, the corner portions 100 that protrude to the outside are cut to make the left side area and the right side area position inside of the circle 53, and an excitation electrode 21a for measurement and an excitation electrode 21b for reference are respectively formed on the right side area and the left side area.
    • 为了提供使用具有用于检测的振荡区域和用于参考的振荡区域的压电传感器的感测装置,并且能够通过改善激励电极的形状来实现高测量灵敏度。 在石英片20a上,设有条形左侧区域和右侧区域,它们对称地形成为相对于圆53的中心彼此分离的左侧和右侧,该中心是平面的轮廓 反应通道52的形状并且以纵向方向平行地延伸。 每个区域被设定为具有左侧区域左侧的两个角部100和右侧区域右侧的两个角部100向圆53的外侧突出的尺寸, 将向外侧突出的部分100切割成在圆53内部的左侧区域和右侧区域位置,并且在右侧区域分别形成用于测量的激励电极21a和用于参考的激励电极21b, 左侧区域。