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1. 发明授权

US4927808A .gamma.-L-glutamyl-L-cysteine ethyl ester and pharmaceutical compositions containing the same as an effective ingredient 失效
标题翻译： γ-谷氨酰-L-半胱氨酸乙酯和含有该组合物的有效成分的药物组合物
公开(公告)号：US4927808A
公开(公告)日：1990-05-22
申请号：US180868
申请日：1988-03-07
申请人： Shigehisa Kitahara , Akira Ohtsu , Katsuhiko Fujii
发明人： Shigehisa Kitahara , Akira Ohtsu , Katsuhiko Fujii
IPC分类号： A61K31/195 , A61K31/22 , C07C323/59 , C07K5/02
CPC分类号： A61K31/195 , A61K31/22 , C07K5/02
摘要： .gamma.-L-glutamyl-L-cysteine ethyl ester which has an activity to increase glutathione levels in tissues and a drug for treating liver diseases, cataracts, and kidney diseases containing it as the effective ingredient.

2. 发明授权

US4472428A Halogenated prostacyclins pharmaceutical use thereof and hydroxy intermediates therefore 失效
标题翻译：因此，其卤化前列环素及其羟基中间体
公开(公告)号：US4472428A
公开(公告)日：1984-09-18
申请号：US327741
申请日：1981-12-04
申请人： Takeshi Toru , Kiyoshi Bannai , Takeo Oba , Toshio Tanaka , Noriaki Okamura , Kenzo Wantanabe , Seizi Kurozumi , Akira Ohtsu , Tatsuyuki Naruchi
发明人： Takeshi Toru , Kiyoshi Bannai , Takeo Oba , Toshio Tanaka , Noriaki Okamura , Kenzo Wantanabe , Seizi Kurozumi , Akira Ohtsu , Tatsuyuki Naruchi
IPC分类号： C07D307/937 , A61K31/557 , C07D307/935
CPC分类号： C07D307/937
摘要： Novel 5- or 7-monohalogenated or 5,7-dihalogenated .sup.6 -PGI.sub.1 and 5- or 7-monohalogenated or dihalogenated PGI.sub.2 (except 5-monofluorinated PGI.sub.2). The novel halogenated prostacyclins are useful for controlling vascular actions and also in organ transplantation, extra-corporeal circulation and the like. The present invention also provides processes for preparing the novel halogenated prostacyclins.
摘要翻译： 5-或7-单卤代或5,7-二卤代6-PGI1和5-或7-单卤代或二卤代PGI2（5-单氟化PGI2除外）。新型卤代前列环素可用于控制血管作用，还可用于器官移植，体外循环等。本发明还提供了制备新型卤代前列环素的方法。

3. 发明授权

US07583395B2 Image forming apparatus and image forming method with synchronous and asynchronous control for continuous operation 失效
标题翻译：用于连续操作的图像形成装置和具有同步和异步控制的图像形成方法
公开(公告)号：US07583395B2
公开(公告)日：2009-09-01
申请号：US10003257
申请日：2001-12-06
申请人： Akira Ohtsu
发明人： Akira Ohtsu
IPC分类号： G06K15/00 , G03G15/00
CPC分类号： G03G15/55 , H04N1/00912 , H04N1/32358 , H04N1/32443 , H04N1/32609 , H04N1/3263 , H04N1/32635 , H04N1/32673 , H04N2201/0081 , H04N2201/0082 , H04N2201/0086 , H04N2201/3287
摘要： An image forming method reads a document by a scanner that is a device, provides image data corresponding to a document image, forms an image corresponding to the image data provided from the scanner by a printer that is a device, and detects operating errors of the scanner and the printer. Further, when any operating error is detected, the image forming method stops the operation of the device generating the error and operates the device not generating the error.
摘要翻译：图像形成方法通过作为设备的扫描仪读取文档，提供与文档图像相对应的图像数据，通过作为设备的打印机形成与从扫描仪提供的图像数据相对应的图像，并且检测文档的操作错误扫描仪和打印机。此外，当检测到任何操作错误时，图像形成方法停止产生错误的装置的操作，并且操作不产生错误的装置。

4. 发明授权

US4402975A Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical uses thereof 失效
公开(公告)号：US4402975A
公开(公告)日：1983-09-06
申请号：US284562
申请日：1981-07-17
申请人： Toru Takeshita , Kenji Hoshina , Akira Ohtsu , Tatsuyuki Naruchi
发明人： Toru Takeshita , Kenji Hoshina , Akira Ohtsu , Tatsuyuki Naruchi
IPC分类号： A61K31/135 , A61K31/195 , A61K31/24 , C07D295/18 , C07C101/34
CPC分类号： C07C229/34 , A61K31/135 , C07C225/18 , C07C233/51 , C07C2101/14 , Y10S514/927 , Y10S514/928
摘要： A compound represented by the following formula ##STR1## wherein R.sup.1 represents a hydrogen atom, an acyl group or an alkoxycarbonyl group; X.sup.1 represents an alkylene group having 3 to 6 carbon atoms, a 1,4-cyclohexylene group, or a 1,4-phenylene group, the alkylene group may be substituted by an alkyl group having 1 to 6 carbon atoms, and the 1,4-phenylene group may be substituted by 1 or 2 substituents selected from halogen atoms and alkoxy groups having 1 to 6 carbon atoms; R.sup.2 represents a hydrogen atom or a hydroxyl group and R.sup.3 represents hydrogen atom, or R.sup.2 and R.sup.3 together may form an oxo group (.dbd.O), and when X.sup.1 is other than the 1,4-phenylene group, R.sup.2 represents a hydrogen atom and R.sup.3 represents a bond between the carbon atoms to which R.sup.3 is bonded and that carbon atom of X.sup.1 which is adjacent to said carbon atom; X.sup.2 represents an alkylene group having 1 to 5 carbon atoms which may be substituted by an alkyl group having 1 to 6 carbon atoms or an amino group; and R.sup.4 represents the group --COOR.sup.5, --CH.sub.2 OR.sup.6 or --CONR.sup.7 R.sup.8 in which R.sup.5 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, R.sup.6 represents a hydrogen atom or an acyl group having 1 to 6 carbon atoms, and R.sup.7 and R are identical or different and represent a hydrogen atom or an alkyl group having 1 to 6 carbon atoms or taken together may form a 5- or 6-membered ring; or an acid addition salts of said compound wherein R.sup.1 represents a hydrogen atom or X.sup.2 represents an alkylene group having an amino group, or salts of said compound wherein R.sup.5 represents a hydrogen atom.The compounds represented by the above formula or their pharmaceutically acceptable salts are useful as anti-ulcer agents.The present invention also provides a process for producing the compounds or their pharmaceutically acceptable salts, which comprises acylating a protected derivative at the amino group of a corresponding acid halide with a corresponding substituted benzene in the presence of a Lewis acid; or reducing a corresponding compound in the presence of an inert solvent under conditions which induce reduction of the carbonyl group of said corresponding compound without substantially reducing the phenylene group of said corresponding compound; or dehydrating a corresponding compound.

5. 发明授权

US5970181A Image-scanning apparatus with a shading correction function 失效
标题翻译：具有阴影校正功能的图像扫描装置
公开(公告)号：US5970181A
公开(公告)日：1999-10-19
申请号：US919261
申请日：1997-08-28
申请人： Akira Ohtsu
发明人： Akira Ohtsu
IPC分类号： H04N1/10 , H04N1/04 , H04N1/107 , H04N1/401 , H04N1/407 , H04N1/40
CPC分类号： H04N1/4076
摘要： An image-scanning apparatus for scanning an original in an image-reading area to output image data, includes, a platen on which the original is placed, a reference plate which has a reference color, and a scanning device for optically scanning the reference plate and the original placed on the platen to provide a first optical image and a second optical image. The image-scanning apparatus also has a receiving device for receiving the first optical image and the second optical image so as to output electrical signals, a setting device for setting a correcting amount on the basis of the electrical signals, a correcting device for correcting the scattering of the electrical signals to output the image data, a calculating device for calculating a pre-running length corresponding to a predetermined speed, the scanning device is accelerated in a pre-running portion corresponding to the pre-running length so that the scanning device reaches the predetermined speed, a determining device for determining that the reference plate is sufficiently included in the pre-running portion, a control system for controlling the scanning device and the setting device corresponding to the detecting operation of the determining device so that the scanning device performs the scanning operation efficiently.
摘要翻译：一种用于扫描图像读取区域中的原稿以输出图像数据的图像扫描装置包括：放置原稿的压板，具有基准颜色的参考板;以及用于光学扫描参考板的扫描装置并且原稿放置在压板上以提供第一光学图像和第二光学图像。图像扫描装置还具有用于接收第一光学图像和第二光学图像以便输出电信号的接收装置，用于基于电信号设置校正量的设置装置，用于校正电信号的散射以输出图像数据;计算装置，用于计算与预定速度对应的预运行长度;扫描装置在对应于预运行长度的预运行部分中被加速，使得扫描装置达到预定速度，用于确定参考板充分包括在预运行部分中的确定装置，用于根据确定装置的检测操作控制扫描装置和设置装置的控制系统，使得扫描装置高效执行扫描操作。

6. 发明授权

US5364883A Isocarbocyclins for the treatment of liver and kidney diseases 失效
标题翻译： Isocarbocyclins用于治疗肝肾疾病
公开(公告)号：US5364883A
公开(公告)日：1994-11-15
申请号：US55787
申请日：1993-05-03
申请人： Kiyoshi Bannai , Toshio Tanaka , Yoshinori Kato , Tamotsu Koyama , Satoshi Asano , Akira Ohtsu , Seizi Kurozumi , Makoto Ogawa , Yoshio Mori
发明人： Kiyoshi Bannai , Toshio Tanaka , Yoshinori Kato , Tamotsu Koyama , Satoshi Asano , Akira Ohtsu , Seizi Kurozumi , Makoto Ogawa , Yoshio Mori
IPC分类号： A61K31/557
CPC分类号： A61K31/557
摘要： 16(S)-Isocarbacyclins have been found to the useful in the treatment of liver and kidney diseases.
摘要翻译：已发现16（S） - 碳青霉烯可用于治疗肝肾疾病。

7. 发明申请

US20120212765A1 IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD WITH SYNCHRONOUS AND ASYNCHRONOUS CONTROL FOR CONTINUOUS OPERATION 审中-公开
标题翻译：具有连续操作同步和异步控制的图像形成装置和图像形成方法
公开(公告)号：US20120212765A1
公开(公告)日：2012-08-23
申请号：US13462106
申请日：2012-05-02
申请人： Akira Ohtsu
发明人： Akira Ohtsu
IPC分类号： G06F3/12 , G06K15/02
CPC分类号： G03G15/55 , H04N1/00912 , H04N1/32358 , H04N1/32443 , H04N1/32609 , H04N1/3263 , H04N1/32635 , H04N1/32673 , H04N2201/0081 , H04N2201/0082 , H04N2201/0086 , H04N2201/3287
摘要： An image forming method reads a document by a scanner that is a device, provides image data corresponding to a document image, forms an image corresponding to the image data provided from the scanner by a printer that is a device, and detects operating errors of the scanner and the printer. Further, when any operating error is detected, the image forming method stops the operation of the device generating the error and operates the device not generating the error.
摘要翻译：图像形成方法通过作为设备的扫描仪读取文档，提供与文档图像相对应的图像数据，通过作为设备的打印机形成与从扫描仪提供的图像数据相对应的图像，并且检测文档的操作错误扫描仪和打印机。此外，当检测到任何操作错误时，图像形成方法停止产生错误的装置的操作，并且操作不产生错误的装置。

8. 发明授权

US06839154B1 Image forming apparatus 失效
标题翻译：图像形成装置
公开(公告)号：US06839154B1
公开(公告)日：2005-01-04
申请号：US09497230
申请日：2000-02-03
申请人： Akira Ohtsu
发明人： Akira Ohtsu
IPC分类号： G03B27/72 , G06K9/32 , G06K9/36 , G06T1/00 , H04N1/04 , H04N1/32 , H04N1/387 , H04N1/393 , H04N1/46
CPC分类号： H04N1/3935 , H04N1/00795 , H04N1/00816
摘要： A system CPU checks whether a copying mode is selected. If the copying mode is selected, the system CPU calculates “read area=periphery of original 2−mm×100÷magnification.” If the copying mode is not selected, the system CPU checks whether a resolution conversion is effective or not. If the resolution conversion is not effective, the system CPU calculates “read area=periphery of original−2 mm×100÷magnification.” If the resolution conversion is effective, the system CPU calculates “read area=periphery of original−2 mm.” The system CPU instructs the scanner CPU to start scanning with the calculated read area.
摘要翻译：系统CPU检查是否选择复印模式。如果选择了复印模式，则系统CPU计算“读取区域=原始2-mmx100 /放大倍数的周边”。如果未选择复印模式，系统CPU会检查分辨率转换是否有效。如果分辨率转换无效，则系统CPU计算“读取区域=原始-2mmx100 /放大倍率的周边”。如果分辨率转换有效，则系统CPU计算“读取区域=原始外围2mm”。系统CPU指示扫描仪CPU以计算的读取区域开始扫描。

9. 发明授权

US4466980A Thiaprostaglandin E.sub.1 derivatives, process for production thereof, and pharmaceutical use thereof 失效
标题翻译： Thiaprostaglandin E1衍生物，其制备方法及其药物用途
公开(公告)号：US4466980A
公开(公告)日：1984-08-21
申请号：US316902
申请日：1981-10-30
申请人： Toshio Tanaka , Takeshi Toru , Takeo Oba , Noriaki Okamura , Kenzo Watanabe , Kiyoshi Bannai , Atsuo Hazato , Seizi Kurozumi , Fukuyoshi Kamimoto , Akira Ohtsu
发明人： Toshio Tanaka , Takeshi Toru , Takeo Oba , Noriaki Okamura , Kenzo Watanabe , Kiyoshi Bannai , Atsuo Hazato , Seizi Kurozumi , Fukuyoshi Kamimoto , Akira Ohtsu
IPC分类号： C07C405/00 , C07D309/12 , C07C177/00 , A61K31/557
CPC分类号： C07C405/0033 , C07D309/12
摘要： A novel compound selected from the group consisting of 7-(or 6- or 4-)thiaprostaglandin E.sub.1 derivatives of the formula (I). ##STR1## wherein A represents --CH.sub.2 -- or ##STR2## in which n is 0, 1 or 2, provided that only one A cut of three is ##STR3## R.sup.1 -R.sup.7 and G are as defined in the specification, the 15-epimers of said thiaprostaglandin E.sub.1 derivatives, the enatiomers of said thiaprostaglandin E.sub.1 derivatives or their 15-epimers, and mixtures of these compounds.A 7-thiaprostaglandin E.sub.1 derivative and/or its optical isomer may be prepared by reacting a 2-organo-2-cyclopentenone (II) with an organic copper-lithium compound (III) to effect conjugation reaction. A 6-thiaprostaglandin E.sub.1 derivative and/or its optical isomer may be prepared by subjecting an .alpha.,.beta.-unsaturated ketone (IV) and a thiol (V) to the Michael addition reaction. And, 4-thiaprostaglandin derivative and/or its optical isomer may also be prepared by the Michael addition reaction from a 2-allyl substituted cyclopentanone (VI) and a thiol (VIII).Some compounds ((I)-1) amongst the compounds of the formula (I) and/or their optical isomer are useful for controlling vascular actions such as angina pectoris, vasodilation etc.
摘要翻译：选自式（I）的7-（或6-或4-）赖氨酸前列腺素E1衍生物的新化合物。（I）其中A表示-CH 2 - 或，其中n为0,1或2，条件是三个只有一个A切割是R 1 -R 7，G如说明书中所定义，所述thiaprostaglandin E1衍生物的15-差向异构体，所述thiaprostaglandin E1衍生物或它们的15-差向异构体的对映体，以及这些化合物的混合物。 7-硫代前列腺素E1衍生物和/或其旋光异构体可以通过2-有机-2-环戊烯酮（II）与有机铜 - 锂化合物（III）反应来制备共轭反应。 6-硫代前列腺素E1衍生物和/或其旋光异构体可以通过使α，β-不饱和酮（IV）和硫醇（V）进行迈克尔加成反应来制备。并且，也可以通过从2-烯丙基取代的环戊酮（VI）和硫醇（VIII）的迈克尔加成反应制备4-硫代前列腺素衍生物和/或其旋光异构体。式（I）化合物和/或其旋光异构体中的一些化合物（（I）-1）可用于控制血管作用，例如心绞痛，血管舒张等。

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