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1. 发明申请

US20100268067A1 SYSTEMS, METHODS, APPARATUSES, AND COMPUTER-READABLE MEDIA FOR IMAGE GUIDED SURGERY 有权
标题翻译：图像引导手术的系统，方法，设备和计算机可读介质
公开(公告)号：US20100268067A1
公开(公告)日：2010-10-21
申请号：US12703118
申请日：2010-02-09
申请人： Sharif Razzaque , John Martinie , David Iannitti , Andrei State , Brian Heaney , Allan Siperstein , Kurtis Keller
发明人： Sharif Razzaque , John Martinie , David Iannitti , Andrei State , Brian Heaney , Allan Siperstein , Kurtis Keller
IPC分类号： A61B5/05
CPC分类号： A61B34/20 , A61B8/4245 , A61B18/02 , A61B18/082 , A61B18/1442 , A61B18/1477 , A61B18/18 , A61B18/1815 , A61B18/20 , A61B34/10 , A61B34/25 , A61B90/37 , A61B2018/00577 , A61B2018/1425 , A61B2018/1869 , A61B2034/102 , A61B2034/104 , A61B2034/107 , A61B2034/2051 , A61B2034/207 , A61B2034/2072 , A61B2090/368 , A61B2090/378 , A61B2090/3983 , A61B2090/502 , B33Y80/00
摘要： Presented herein are methods, systems, devices, and computer-readable media for image guided surgery. The systems herein allow a physician to use multiple instruments for a surgery and simultaneously provide image-guidance data for those instruments. Various embodiments disclosed herein provide information to physicians about procedures they are performing, the devices (such as ablation needles, ultrasound wands or probes, scalpels, cauterizers, etc.) they are using during the procedure, the relative emplacements or poses of these devices, prediction information for those devices, and other information. Some embodiments provide useful information about 3D data sets. Additionally, some embodiments provide for quickly calibratable surgical instruments or attachments for surgical instruments.
摘要翻译：这里提出了用于图像引导手术的方法，系统，装置和计算机可读介质。这里的系统允许医师使用多个仪器进行手术，并同时提供这些仪器的图像引导数据。本文公开的各种实施例向医生提供关于它们正在执行的程序的信息，在程序期间它们正在使用的装置（例如消融针，超声波棒或探针，解剖刀，烧灼器等），这些装置的相对位置或姿势，这些设备的预测信息和其他信息。一些实施例提供关于3D数据集的有用信息。另外，一些实施例提供用于外科器械的快速可校准外科器械或附件。

2. 发明申请

US20080030578A1 SYSTEM AND METHOD OF PROVIDING REAL-TIME DYNAMIC IMAGERY OF A MEDICAL PROCEDURE SITE USING MULTIPLE MODALITIES 有权
标题翻译：使用多种模式提供医疗程序实时动态图像的系统和方法
公开(公告)号：US20080030578A1
公开(公告)日：2008-02-07
申请号：US11833134
申请日：2007-08-02
申请人： Sharif Razzaque , Kurtis Keller , Andrei State , Caroline Green , Jeremy Ackerman
发明人： Sharif Razzaque , Kurtis Keller , Andrei State , Caroline Green , Jeremy Ackerman
IPC分类号： H04N7/18
CPC分类号： G06T3/0087 , A61B1/0005 , A61B1/042 , A61B1/313 , A61B8/12 , A61B8/463 , A61B8/5238 , H04N7/181
摘要： A system and method of providing composite real-time dynamic imagery of a medical procedure site from multiple modalities which continuously and immediately depicts the current state and condition of the medical procedure site synchronously with respect to each modality and without undue latency is disclosed. The composite real-time dynamic imagery may be provided by spatially registering multiple real-time dynamic video streams from the multiple modalities to each other. Spatially registering the multiple real-time dynamic video streams to each other may provide a continuous and immediate depiction of the medical procedure site with an unobstructed and detailed view of a region of interest at the medical procedure site at multiple depths. As such, a surgeon, or other medical practitioner, may view a single, accurate, and current composite real-time dynamic imagery of a region of interest at the medical procedure site as he/she performs a medical procedure, and thereby, may properly and effectively implement the medical procedure.
摘要翻译：公开了一种从多种模式提供医疗程序现场的复合实时动态图像的系统和方法，其连续并立即描绘了相对于每个模态并且没有不适当延迟的医疗程序现场的当前状态和状况。复合实时动态图像可以通过将来自多个模态的多个实时动态视频流空间注册到彼此来提供。将多个实时动态视频流空间注册到彼此可以提供医疗程序站点的连续且立即的描述，其中在医疗程序站点的多个深度处，不受阻碍地和详细地观察感兴趣的区域。因此，外科医生或其他医生可以在执行医疗程序时在医疗程序现场查看感兴趣区域的单一，准确和当前的复合实时动态图像，从而可以适当地有效实施医疗程序。

3. 发明申请

US20110130641A1 IMAGER FOCUSING BASED ON INTRAOPERATIVE DATA 有权
标题翻译：基于内在数据的图像聚焦
公开(公告)号：US20110130641A1
公开(公告)日：2011-06-02
申请号：US12949449
申请日：2010-11-18
申请人： Sharif Razzaque , Andrei State , Kurtis Keller
发明人： Sharif Razzaque , Andrei State , Kurtis Keller
IPC分类号： A61B5/05
CPC分类号： A61B8/5238 , A61B5/06 , A61B5/062 , A61B5/067 , A61B8/0833 , A61B8/0841 , A61B8/4245 , A61B8/4254 , G01S7/52034 , G01S15/8979 , G01S15/8988 , G01S15/8993
摘要： Various embodiments herein provide for imager focusing based on intraoperative data. Ideally, an imaging plane of an ultrasound transducer would be truly planar. That is not the case, though. Instead, ultrasound transducers image a volume that is closer to a rectangular volume, but that has focal depths or areas in the imaged volume that are “thinner” and provide a better resolution. In general, embodiments herein may include determining the pose of an imager, such as an ultrasound transducer, and the pose of a location of interest. Based on those poses, a focal adjustment may be determined in order to, for example, better focus the imager on the object of interest. Then data is generated and the focus of the imager is adjusted. Additionally, imaging data and/or the object of interest may be displayed. In other embodiments, estimated projections of medical devices are displayed to allow for better intraoperative planning.
摘要翻译：本文中的各种实施例提供了基于术中数据的成像器聚焦。理想地，超声换能器的成像平面将是真正的平面的。不是这样的。相反，超声波传感器对更接近于矩形体积的体积进行成像，但是成像体积中的焦点深度或区域“更薄”并提供更好的分辨率。通常，本文的实施例可以包括确定诸如超声换能器的成像器的姿态和感兴趣位置的姿态。基于这些姿势，可以确定焦点调整，以便例如更好地将成像器重点放在感兴趣的对象上。然后生成数据，并调整成像器的焦点。此外，可以显示成像数据和/或感兴趣的对象。在其他实施例中，显示医疗装置的估计投影以允许更好的术中规划。

4. 发明授权

US09282947B2 Imager focusing based on intraoperative data 有权
标题翻译：基于术中数据的成像仪聚焦
公开(公告)号：US09282947B2
公开(公告)日：2016-03-15
申请号：US12949449
申请日：2010-11-18
申请人： Sharif Razzaque , Andrei State , Kurtis Keller
发明人： Sharif Razzaque , Andrei State , Kurtis Keller
IPC分类号： A61B5/05 , A61B8/08 , A61B8/00 , G01S7/52 , G01S15/89 , A61B5/06
CPC分类号： A61B8/5238 , A61B5/06 , A61B5/062 , A61B5/067 , A61B8/0833 , A61B8/0841 , A61B8/4245 , A61B8/4254 , G01S7/52034 , G01S15/8979 , G01S15/8988 , G01S15/8993
摘要： Various embodiments herein provide for imager focusing based on intraoperative data. Ideally, an imaging plane of an ultrasound transducer would be truly planar. That is not the case, though. Instead, ultrasound transducers image a volume that is closer to a rectangular volume, but that has focal depths or areas in the imaged volume that are “thinner” and provide a better resolution. In general, embodiments herein may include determining the pose of an imager, such as an ultrasound transducer, and the pose of a location of interest. Based on those poses, a focal adjustment may be determined in order to, for example, better focus the imager on the object of interest. Then data is generated and the focus of the imager is adjusted. Additionally, imaging data and/or the object of interest may be displayed. In other embodiments, estimated projections of medical devices are displayed to allow for better intraoperative planning.
摘要翻译：本文中的各种实施例提供了基于术中数据的成像器聚焦。理想地，超声换能器的成像平面将是真正的平面的。不是这样的。相反，超声波传感器对更接近于矩形体积的体积进行成像，但是成像体积中的焦点深度或区域“更薄”并提供更好的分辨率。通常，本文的实施例可以包括确定诸如超声换能器的成像器的姿态和感兴趣位置的姿态。基于这些姿势，可以确定焦点调整，以便例如更好地将成像器重点放在感兴趣的对象上。然后生成数据，并调整成像器的焦点。此外，可以显示成像数据和/或感兴趣的对象。在其他实施例中，显示医疗装置的估计投影以允许更好的术中规划。

5. 发明授权

US08585598B2 Systems, methods, apparatuses, and computer-readable media for image guided surgery 有权
标题翻译：用于图像引导手术的系统，方法，装置和计算机可读介质
公开(公告)号：US08585598B2
公开(公告)日：2013-11-19
申请号：US13333745
申请日：2011-12-21
申请人： Sharif Razzaque , John Martinie , David Iannitti , Andrei State , Brian Heaney , Allan Siperstein , Kurtis Keller
发明人： Sharif Razzaque , John Martinie , David Iannitti , Andrei State , Brian Heaney , Allan Siperstein , Kurtis Keller
IPC分类号： A61B8/00
CPC分类号： A61B34/20 , A61B8/4245 , A61B18/02 , A61B18/082 , A61B18/1442 , A61B18/1477 , A61B18/18 , A61B18/1815 , A61B18/20 , A61B34/10 , A61B34/25 , A61B90/37 , A61B2018/00577 , A61B2018/1425 , A61B2018/1869 , A61B2034/102 , A61B2034/104 , A61B2034/107 , A61B2034/2051 , A61B2034/207 , A61B2034/2072 , A61B2090/368 , A61B2090/378 , A61B2090/3983 , A61B2090/502 , B33Y80/00
摘要： Presented herein are methods, systems, devices, and computer-readable media for image guided surgery. The systems herein allow a physician to use multiple instruments for a surgery and simultaneously provide image-guidance data for those instruments. Various embodiments disclosed herein provide information to physicians about procedures they are performing, the devices (such as ablation needles, ultrasound wands or probes, scalpels, cauterizers, etc.) they are using during the procedure, the relative emplacements or poses of these devices, prediction information for those devices, and other information. Some embodiments provide useful information about 3D data sets. Additionally, some embodiments provide for quickly calibratable surgical instruments or attachments for surgical instruments.
摘要翻译：这里提出了用于图像引导手术的方法，系统，装置和计算机可读介质。这里的系统允许医师使用多个仪器进行手术，并同时提供这些仪器的图像引导数据。本文公开的各种实施例向医生提供关于它们正在执行的程序的信息，他们在手术期间正在使用的装置（例如消融针，超声波棒或探针，解剖刀，烧灼器等），这些装置的相对位置或姿势，这些设备的预测信息和其他信息。一些实施例提供关于3D数据集的有用信息。另外，一些实施例提供用于外科器械的快速可校准外科器械或附件。

6. 发明授权

US08690776B2 Systems, methods, apparatuses, and computer-readable media for image guided surgery 有权
标题翻译：用于图像引导手术的系统，方法，装置和计算机可读介质
公开(公告)号：US08690776B2
公开(公告)日：2014-04-08
申请号：US12703118
申请日：2010-02-09
申请人： Sharif Razzaque , John Martinie , David Iannitti , Andrei State , Brian Heaney , Allan Siperstein , Kurtis Keller
发明人： Sharif Razzaque , John Martinie , David Iannitti , Andrei State , Brian Heaney , Allan Siperstein , Kurtis Keller
IPC分类号： A61B8/00
CPC分类号： A61B34/20 , A61B8/4245 , A61B18/02 , A61B18/082 , A61B18/1442 , A61B18/1477 , A61B18/18 , A61B18/1815 , A61B18/20 , A61B34/10 , A61B34/25 , A61B90/37 , A61B2018/00577 , A61B2018/1425 , A61B2018/1869 , A61B2034/102 , A61B2034/104 , A61B2034/107 , A61B2034/2051 , A61B2034/207 , A61B2034/2072 , A61B2090/368 , A61B2090/378 , A61B2090/3983 , A61B2090/502 , B33Y80/00
摘要： Presented herein are methods, systems, devices, and computer-readable media for image guided surgery. The systems herein allow a physician to use multiple instruments for a surgery and simultaneously provide image-guidance data for those instruments. Various embodiments disclosed herein provide information to physicians about procedures they are performing, the devices (such as ablation needles, ultrasound wands or probes, scalpels, cauterizers, etc.) they are using during the procedure, the relative emplacements or poses of these devices, prediction information for those devices, and other information. Some embodiments provide useful information about 3D data sets. Additionally, some embodiments provide for quickly calibratable surgical instruments or attachments for surgical instruments.
摘要翻译：这里提出了用于图像引导手术的方法，系统，装置和计算机可读介质。这里的系统允许医师使用多个仪器进行手术，并同时提供这些仪器的图像引导数据。本文公开的各种实施例向医生提供关于它们正在执行的程序的信息，在程序期间它们正在使用的装置（例如消融针，超声波棒或探针，解剖刀，烧灼器等），这些装置的相对位置或姿势，这些设备的预测信息和其他信息。一些实施例提供关于3D数据集的有用信息。另外，一些实施例提供用于外科器械的快速可校准外科器械或附件。

7. 发明授权

US08482606B2 System and method of providing real-time dynamic imagery of a medical procedure site using multiple modalities 有权
标题翻译：使用多种方式提供医疗程序现场实时动态图像的系统和方法
公开(公告)号：US08482606B2
公开(公告)日：2013-07-09
申请号：US12760274
申请日：2010-04-14
申请人： Sharif Razzaque , Kurtis Keller , Andrei State , Caroline Green , Jeremy Ackerman
发明人： Sharif Razzaque , Kurtis Keller , Andrei State , Caroline Green , Jeremy Ackerman
IPC分类号： H04N7/18
CPC分类号： G06T3/0087 , A61B1/0005 , A61B1/042 , A61B1/313 , A61B8/12 , A61B8/463 , A61B8/5238 , H04N7/181
摘要： A system and method of providing composite real-time dynamic imagery of a medical procedure site from multiple modalities which continuously and immediately depicts the current state and condition of the medical procedure site synchronously with respect to each modality and without undue latency is disclosed. The composite real-time dynamic imagery may be provided by spatially registering multiple real-time dynamic video streams from the multiple modalities to each other. Spatially registering the multiple real-time dynamic video streams to each other may provide a continuous and immediate depiction of the medical procedure site with an unobstructed and detailed view of a region of interest at the medical procedure site at multiple depths. As such, a surgeon, or other medical practitioner, may view a single, accurate, and current composite real-time dynamic imagery of a region of interest at the medical procedure site as he/she performs a medical procedure, and thereby, may properly and effectively implement the medical procedure.
摘要翻译：公开了一种从多种模式提供医疗程序现场的复合实时动态图像的系统和方法，其连续并立即描绘了相对于每个模态并且没有不适当延迟的医疗程序现场的当前状态和状况。复合实时动态图像可以通过将来自多个模态的多个实时动态视频流空间注册到彼此来提供。将多个实时动态视频流空间注册到彼此可以提供医疗程序站点的连续且立即的描述，其中在医疗程序站点的多个深度处，不受阻碍地和详细地观察感兴趣的区域。因此，外科医生或其他医生可以在执行医疗程序时在医疗程序现场查看感兴趣区域的单一，准确和当前的复合实时动态图像，从而可以适当地有效实施医疗程序。

8. 发明申请

US20120101370A1 SYSTEMS, METHODS, APPARATUSES, AND COMPUTER-READABLE MEDIA FOR IMAGE GUIDED SURGERY 有权
标题翻译：图像引导手术的系统，方法，设备和计算机可读介质
公开(公告)号：US20120101370A1
公开(公告)日：2012-04-26
申请号：US13333745
申请日：2011-12-21
申请人： Sharif Razzaque , John Martinie , David Iannitti , Andrei State , Brian Heaney , Allan Siperstein , Kurtis Keller
发明人： Sharif Razzaque , John Martinie , David Iannitti , Andrei State , Brian Heaney , Allan Siperstein , Kurtis Keller
IPC分类号： A61B6/00
CPC分类号： A61B34/20 , A61B8/4245 , A61B18/02 , A61B18/082 , A61B18/1442 , A61B18/1477 , A61B18/18 , A61B18/1815 , A61B18/20 , A61B34/10 , A61B34/25 , A61B90/37 , A61B2018/00577 , A61B2018/1425 , A61B2018/1869 , A61B2034/102 , A61B2034/104 , A61B2034/107 , A61B2034/2051 , A61B2034/207 , A61B2034/2072 , A61B2090/368 , A61B2090/378 , A61B2090/3983 , A61B2090/502 , B33Y80/00
摘要： Presented herein are methods, systems, devices, and computer-readable media for image guided surgery. The systems herein allow a physician to use multiple instruments for a surgery and simultaneously provide image-guidance data for those instruments. Various embodiments disclosed herein provide information to physicians about procedures they are performing, the devices (such as ablation needles, ultrasound wands or probes, scalpels, cauterizers, etc.) they are using during the procedure, the relative emplacements or poses of these devices, prediction information for those devices, and other information. Some embodiments provide useful information about 3D data sets. Additionally, some embodiments provide for quickly calibratable surgical instruments or attachments for surgical instruments.
摘要翻译：这里提出了用于图像引导手术的方法，系统，装置和计算机可读介质。这里的系统允许医师使用多个仪器进行手术，并同时提供这些仪器的图像引导数据。本文公开的各种实施例向医生提供关于它们正在执行的程序的信息，在程序期间它们正在使用的装置（例如消融针，超声波棒或探针，解剖刀，烧灼器等），这些装置的相对位置或姿势，这些设备的预测信息和其他信息。一些实施例提供关于3D数据集的有用信息。另外，一些实施例提供用于外科器械的快速可校准外科器械或附件。

9. 发明申请

US20090312629A1 CORRECTION OF RELATIVE TRACKING ERRORS BASED ON A FIDUCIAL 审中-公开
标题翻译：相对跟踪错误校正基于一个FIDUCIAL
公开(公告)号：US20090312629A1
公开(公告)日：2009-12-17
申请号：US12483099
申请日：2009-06-11
申请人： Sharif Razzaque , Andrei State , Caroline Green , Kurtis Keller
发明人： Sharif Razzaque , Andrei State , Caroline Green , Kurtis Keller
IPC分类号： A61B5/05 , A61B8/00
CPC分类号： A61B5/06 , A61B5/7445 , A61B18/1477 , A61B34/20 , A61B2018/1425 , A61B2034/2051 , A61B2034/2063 , A61B2034/2065 , A61B2034/2068 , A61B2090/378
摘要： Presented herein are methods, systems, devices, and computer-readable media for correction of relative tracking error based on a fiducial. One embodiment is a method for the correction of obtained emplacement data of two surgical instruments by the detection of a detectable fiducial coupled to first surgical instrument by a second surgical instrument or something thereto coupled. The corrected relative emplacements of both surgical instruments is then determined based on the emplacement of the fiducial. This corrected emplacement is then used to produce an image for display. Systems and devices for carrying out the presented methods are also described.
摘要翻译：这里提出的是用于基于基准来校正相对跟踪误差的方法，系统，设备和计算机可读介质。一个实施例是一种用于通过检测由第二外科器械耦合到第一外科器械的可检测基准或其耦合的东西来校正两个手术器械的获得的位置数据的方法。然后根据基准的位置来确定两个手术器械的校正的相对位置。然后将该校正后的位置用于产生用于显示的图像。还描述了用于执行所提出的方法的系统和设备。

10. 发明申请

US20060184040A1 Apparatus, system and method for optically analyzing a substrate 审中-公开
标题翻译：用于光学分析衬底的装置，系统和方法
公开(公告)号：US20060184040A1
公开(公告)日：2006-08-17
申请号：US11295857
申请日：2005-12-07
申请人： Kurtis Keller , Caroline Green , Andrei State , Adam Wax
发明人： Kurtis Keller , Caroline Green , Andrei State , Adam Wax
IPC分类号： A61B6/00
CPC分类号： G01N21/47 , A61B5/0059 , A61B5/0086 , A61B5/14532 , A61B5/445
摘要： An apparatus for optically analyzing a substrate. The apparatus includes: (a) a light source for directing light onto the substrate; (b) optics for creating an optical path from light reflected from the substrate; and (c) a multiple wavelength imaging optical subsystem positioned in the optical path. The multiple wavelength imaging optical subsystem includes: (i) one or more filters which are capable of one or both of: (1) being alternatively or sequentially interposed in the optical path to extract one or more of wavelengths or wavelength bands of interest; or (2) having their wavelength selectivity adjusted to extract one or more wavelengths or wavelength bands of interest; and (ii) one or more imaging devices positioned to image the extracted wavelengths or wavelength bands of interest from the one or more filters; (d) an imaging device positioned in the optical path. Also a method is included, making use of the apparatus for analysis of a substrate.
摘要翻译：一种用于光学分析衬底的装置。该装置包括：（a）用于将光引导到基板上的光源; （b）用于从基板反射的光产生光路的光学元件; 和（c）位于光路中的多波长成像光学子系统。多波长成像光学子系统包括：（i）能够具有以下之一或两者的一个或多个滤波器：（1）交替地或顺序插入在光路中以提取感兴趣的波长或波长带中的一个或多个; 或（2）调节其波长选择性以提取感兴趣的一个或多个波长或波长带; 以及（ii）一个或多个成像装置，其定位成从所述一个或多个滤光片成像所提取的所述感兴趣的波长或波长带; （d）位于光路中的成像装置。还包括使用用于分析衬底的装置的方法。

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