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1. 发明申请

US20090048652A1 MEDICAL DEVICE HAVING PLASMA POLYMERIZED COATING AND METHOD THEREFOR 审中-公开
标题翻译：具有等离子体聚合涂层的医疗装置及其方法
公开(公告)号：US20090048652A1
公开(公告)日：2009-02-19
申请号：US11838026
申请日：2007-08-13
申请人： Shamim M. Malik , Paul E. Zarembo , Larry L. Hum
发明人： Shamim M. Malik , Paul E. Zarembo , Larry L. Hum
IPC分类号： A61N1/04 , B05D5/12
CPC分类号： C08J7/18 , A61N1/05 , A61N1/375 , B05D1/62 , B05D2201/00 , B05D2202/00 , B29C65/48 , B29C65/483 , B29C65/4845 , B29C66/001 , B29C66/02 , B29C66/71 , B29C66/742 , B29C66/82661 , B29K2027/18 , B29K2071/00 , B29K2075/00 , B29K2083/00 , B29K2305/00 , B29K2305/12 , B29K2305/14 , B29L2031/753 , B29L2031/7534 , C08J2383/04 , B29K2019/00
摘要： A medical device having at least one plasma polymerized coating allowing for a first component to be coupled with a second component.
摘要翻译：一种具有至少一个等离子体聚合涂层的医疗装置，其允许第一部件与第二部件联接。

2. 发明授权

US08954167B2 Helically formed coil for a neural cuff electrode 有权
标题翻译：用于神经袖口电极的螺旋形线圈
公开(公告)号：US08954167B2
公开(公告)日：2015-02-10
申请号：US12718462
申请日：2010-03-05
申请人： Paul E. Zarembo , Stephen Ruble
发明人： Paul E. Zarembo , Stephen Ruble
IPC分类号： A61N1/05
CPC分类号： A61N1/0556
摘要： A lead assembly for an implantable medical device includes a lead body having a proximal end and a distal end. One or more connectors at the proximal end of the lead body are each adapted for connection to a pulse generator. One or more conductive elements are coupled to the one or more connectors at the proximal end and extend through the lead body to the distal end. Each of the one or more conductive elements includes an electrode coil that extends from the distal end of the lead body that is formed into a helix having a diameter greater than a diameter of the electrode coil.
摘要翻译：用于可植入医疗装置的引线组件包括具有近端和远端的引线体。引线本体的近端处的一个或多个连接器各自适于连接到脉冲发生器。一个或多个导电元件在近端处连接到一个或多个连接器并且通过引线主体延伸到远端。一个或多个导电元件中的每一个包括从引线主体的远端延伸的电极线圈，其形成为直径大于电极线圈直径的螺旋。

3. 发明申请

US20130138188A1 IMPLANTABLE MEDICAL LEADS HAVING OSCILLATING CABLE CONDUCTOR LUMENS 有权
公开(公告)号：US20130138188A1
公开(公告)日：2013-05-30
申请号：US13688016
申请日：2012-11-28
申请人： Lily Lim , Devon N. Arnholt , Joel T. Eggert , Andrew L. De Kock , Paul E. Zarembo , Christopher A. Hartemink
发明人： Lily Lim , Devon N. Arnholt , Joel T. Eggert , Andrew L. De Kock , Paul E. Zarembo , Christopher A. Hartemink
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , B29C45/14065 , B29C45/14262 , B29C45/14819 , Y10T29/49204
摘要： An electrical implantable lead includes an elongated lead body having a plurality of lumens therein, including at least one linear lumen and at least one planar, non-linear lumen and a plurality of conductor cables disposed within the plurality of lumens. The electrical implantable lead further includes a terminal connector coupled to a proximal end of the lead body, the terminal connector being in electrical communication with at least one of the plurality of conductor cables. Further, the electrical implantable lead includes at least one electrode coupled to the lead body, the at least one electrode in electrical communication with at least one of the plurality of conductor cables. In accordance with various embodiments, the at least one non-linear lumen extends longitudinally along a portion of the lead body and includes a plurality or crests and a plurality of troughs.

4. 发明授权

US08027739B2 Medical device having a glass coating and method therefor 有权
标题翻译：具有玻璃涂层的医疗装置及其方法
公开(公告)号：US08027739B2
公开(公告)日：2011-09-27
申请号：US11855088
申请日：2007-09-13
申请人： Peter Hall , Paul E. Zarembo
发明人： Peter Hall , Paul E. Zarembo
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： A medical device having at least one glass coating between a first and second component. The glass coating forms a portion of a strong, hydrothermally stable joint between components or provides insulation, or tailors an impedance and/or capacitance of an electrode.
摘要翻译：一种在第一和第二部件之间具有至少一个玻璃涂层的医疗装置。玻璃涂层在部件之间形成强的，水热稳定的接头的一部分，或提供绝缘，或调整电极的阻抗和/或电容。

5. 发明申请

US20100305674A1 HELICALLY FORMED COIL FOR A NEURAL CUFF ELECTRODE 有权
标题翻译：用于神经铜电极的直线形线圈
公开(公告)号：US20100305674A1
公开(公告)日：2010-12-02
申请号：US12718462
申请日：2010-03-05
申请人： Paul E. Zarembo , Stephen Ruble
发明人： Paul E. Zarembo , Stephen Ruble
IPC分类号： A61N1/05
CPC分类号： A61N1/0556
摘要： A lead assembly for an implantable medical device includes a lead body having a proximal end and a distal end. One or more connectors at the proximal end of the lead body are each adapted for connection to a pulse generator. One or more conductive elements are coupled to the one or more connectors at the proximal end and extend through the lead body to the distal end. Each of the one or more conductive elements includes an electrode coil that extends from the distal end of the lead body that is formed into a helix having a diameter greater than a diameter of the electrode coil.
摘要翻译：用于可植入医疗装置的引线组件包括具有近端和远端的引线体。引线本体的近端处的一个或多个连接器各自适于连接到脉冲发生器。一个或多个导电元件在近端处连接到一个或多个连接器并且通过引线主体延伸到远端。一个或多个导电元件中的每一个包括从引线主体的远端延伸的电极线圈，其形成为直径大于电极线圈直径的螺旋。

6. 发明申请

US20090222074A1 INTERCONNECTIONS OF IMPLANTABLE LEAD CONDUCTORS AND ELECTRODES AND REINFORCEMENT THEREFOR 有权
标题翻译：可导电导体和电极的互连及其加固
公开(公告)号：US20090222074A1
公开(公告)日：2009-09-03
申请号：US12467978
申请日：2009-05-18
申请人： Paul E. Zarembo , Mohan Krishnan , David Durand
发明人： Paul E. Zarembo , Mohan Krishnan , David Durand
IPC分类号： A61N1/05 , H01R43/00
CPC分类号： A61N1/056 , H01R13/18 , H01R2201/12 , Y10T29/49117
摘要： An implantable lead comprises a lead body extending from a lead proximal end portion to a lead distal end portion. The lead body includes one or more longitudinally extending lumens. A conductor is received in, and extends along, a lumen. In varying examples, the implantable lead further comprises a tubular electrode co-axial with, and overlying portions of, the lead body. In one example, a lumen wall is sized and shaped to urge an electrically conductive interposer coupled with the conductor toward an inner surface of the electrode. In another example, a ring member is disposed within a lumen and the conductor is drawn and coupled thereto. In yet another example, an electrically conductive connector couples a first and a second conductor via grooves or threads. In a further example, an axial support member couples a distal end electrode and the lead body. Methods associated with the foregoing are also discussed.
摘要翻译：可植入引线包括从引线近端部分延伸到引线远端部分的引线体。引线体包括一个或多个纵向延伸的腔。导体被容纳在内腔中并沿着其延伸。在可变示例中，可植入引线还包括与引线主体同轴并且覆盖引线主体的部分的管状电极。在一个示例中，腔壁的尺寸和形状被设计成将与导体耦合的导电插入件推向电极的内表面。在另一示例中，环构件设置在管腔内并且导体被拉伸并与其连接。在又一示例中，导电连接器通过凹槽或螺纹将第一和第二导体连接。在另一示例中，轴向支撑构件将远端电极和引线体联接。还讨论了与前述相关的方法。

7. 发明授权

US07571010B2 Cable electrode assembly for a lead terminal and method therefor 有权
标题翻译：一种用于引线端子的电缆电极组件及其方法
公开(公告)号：US07571010B2
公开(公告)日：2009-08-04
申请号：US11123321
申请日：2005-05-06
申请人： Paul E. Zarembo , Mohan Krishnan , Christopher P. Knapp , Russell L. Hoeker
发明人： Paul E. Zarembo , Mohan Krishnan , Christopher P. Knapp , Russell L. Hoeker
IPC分类号： A61N1/18 , A61N1/05 , A61B5/0402
CPC分类号： A61N1/056
摘要： A lead assembly includes a lead body and at least one cables at least partially disposed within the lead body. The cable has a non-electrode portion and an electrode portion, where the non-electrode portion extends within the lead body, and the electrode portion is external to the lead body.
摘要翻译：引线组件包括引线体和至少部分地布置在引线体内的至少一根电缆。电缆具有非电极部分和电极部分，其中非电极部分在引线体内延伸，并且电极部分在引线体外部。

8. 发明授权

US07546165B2 Interconnections of implantable lead conductors and electrodes and reinforcement therefor 有权
标题翻译：可植入引线导体和电极的互连及其加固
公开(公告)号：US07546165B2
公开(公告)日：2009-06-09
申请号：US11305925
申请日：2005-12-19
申请人： Paul E. Zarembo , Mohan Krishnan , David Durand
发明人： Paul E. Zarembo , Mohan Krishnan , David Durand
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , H01R13/18 , H01R2201/12 , Y10T29/49117
摘要： An implantable lead comprises a lead body extending from a lead proximal end portion to a lead distal end portion. The lead body includes one or more longitudinally extending lumens. A conductor is received in, and extends along, a lumen. In varying examples, the implantable lead further comprises a tubular electrode co-axial with, and overlying portions of, the lead body. In one example, a lumen wall is sized and shaped to urge an electrically conductive interposer coupled with the conductor toward an inner surface of the electrode. In another example, a ring member is disposed within a lumen and the conductor is drawn and coupled thereto. In yet another example, an electrically conductive connector couples a first and a second conductor via grooves or threads. In a further example, an axial support member couples a distal end electrode and the lead body. Methods associated with the foregoing are also discussed.
摘要翻译：可植入引线包括从引线近端部分延伸到引线远端部分的引线体。引线体包括一个或多个纵向延伸的腔。导体被容纳在内腔中并沿着其延伸。在可变示例中，可植入引线还包括与引线主体同轴并且覆盖引线主体的部分的管状电极。在一个示例中，腔壁的尺寸和形状被设计成将与导体耦合的导电插入件推向电极的内表面。在另一示例中，环构件设置在管腔内并且导体被拉伸并与其连接。在又一示例中，导电连接器通过凹槽或螺纹将第一和第二导体连接。在另一示例中，轴向支撑构件将远端电极和引线体联接。还讨论了与前述相关的方法。

9. 发明申请

US20080262588A1 LEAD ASSEMBLY AND METHODS INCLUDING A PUSH TUBE 失效
标题翻译：引导组件和包括推管的方法
公开(公告)号：US20080262588A1
公开(公告)日：2008-10-23
申请号：US12163869
申请日：2008-06-27
申请人： Paul E. Zarembo , John Greenland
发明人： Paul E. Zarembo , John Greenland
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0578
摘要： A lead assembly includes an elongate body having a conductor electrically coupled with an electrode coupled to the elongate body. The lead assembly includes a push tube extending along at least a portion of the elongate body. A distal tip is coupled to the elongate body substantially adjacent to the distal end of the elongate body. The distal tip is sized and shaped to couple with a push tube distal end. In one option, the distal tip includes a seat to receive the push tube distal end. In another option, the seat is a side rail seat and a guide wire extends along the elongate body and is slidably coupled with the side rail seat. The lead assembly includes, optionally, an active fixation device slidably coupled with a portion of the elongate body, and the active fixation device is sized and shaped to couple with the push tube.
摘要翻译：引线组件包括细长主体，其具有与耦合到细长主体的电极电耦合的导体。引线组件包括沿细长体的至少一部分延伸的推管。远侧末端与细长体联接，基本上与细长体的远端相邻。远侧末端的尺寸和形状与推管远端连接。在一个选择中，远侧末端包括用于接收推管远端的座。在另一种选择中，座椅是侧轨座，导线沿着细长主体延伸并与侧轨座滑动联接。引导组件可选地包括与细长主体的一部分可滑动地联接的主动固定装置，并且主动固定装置的尺寸和形状与推管相连。

10. 发明申请

US20080262586A1 IMPLANTABLE LEAD FOR SEPTAL PLACEMENT OF PACING ELECTRODES 有权
标题翻译：用于隔离电极的可植入铅
公开(公告)号：US20080262586A1
公开(公告)日：2008-10-23
申请号：US12144247
申请日：2008-06-23
申请人： Yongxing Zhang , James O. Gilkerson , Paul E. Zarembo
发明人： Yongxing Zhang , James O. Gilkerson , Paul E. Zarembo
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N1/056 , A61N2001/0585
摘要： A pacing lead having a lead body configured into a pre-formed J-shape. The lead includes a pacing electrode coupled to an intermediate portion of the lead body and located distally from a bottom of the pre-formed J-shape. The lead is adapted to be placed within a heart in a J-shaped configuration with the electrode positioned proximate a ventricular septum or a right ventricular outflow tract such that at least a portion of the distal end of the lead body is located within a pulmonary artery. In one embodiment, the distal end of the lead is configured to be passively fixated within the pulmonary artery. Another aspect includes a lead body wherein a section of the intermediate portion of the lead body is less stiff than adjacent sections of the lead body. The lead includes a pacing electrode coupled to the intermediate portion of the lead body and located distally from the less stiff section. The lead is adapted to be placed within a heart in a J-shaped configuration with the less stiff section near a bottom of the J-shape such that the electrode is positioned proximate a ventricular septum or a right ventricular outflow tract and at least a portion of the distal end of the lead body is fixated within a pulmonary artery.
摘要翻译：具有构造成预成形的J形的引线主体的起搏引线。引线包括连接到引线主体的中间部分并且位于远离预成形的J形的底部的起搏电极。引线适于放置在J形构型的心脏内，其中电极位于心室隔膜或右心室流出道附近，使得引线体的远端的至少一部分位于肺动脉内。在一个实施例中，引线的远端构造成被动地固定在肺动脉内。另一方面包括引线体，其中引线主体的中间部分的部分比引线本体的相邻部分刚性差。引线包括连接到引线主体的中间部分并位于较不硬的部分的远侧的起搏电极。引线适于放置在心脏内的J形构型中，具有靠近J形底部的较硬的部分，使得电极位于靠近心室隔膜或右心室流出道和至少一部分引导体的远端固定在肺动脉内。

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