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1. 发明授权

US08455493B2 Imidazopyrazine Syk inhibitors 有权
标题翻译：咪唑吡嗪Syk抑制剂
公开(公告)号：US08455493B2
公开(公告)日：2013-06-04
申请号：US12632140
申请日：2009-12-07
申请人： Scott A. Mitchell , Kevin S. Currie , Peter A. Blomgren , Jeffrey E. Kropf , Seung H. Lee , Jianjun Xu , Douglas G. Stafford , James P. Harding , Antonio J. M. Barbosa, Jr. , Zhongdong Zhao , Soumya Mitra , David M. Armistead
发明人： Scott A. Mitchell , Kevin S. Currie , Peter A. Blomgren , Jeffrey E. Kropf , Seung H. Lee , Jianjun Xu , Douglas G. Stafford , James P. Harding , Antonio J. M. Barbosa, Jr. , Zhongdong Zhao , Soumya Mitra , David M. Armistead
IPC分类号： A61K31/495
CPC分类号： C07D487/04 , A61K31/495 , C07D471/04 , C07D491/107 , C07D498/04 , C07D519/00 , C12Q1/485 , G01N33/573 , G01N2333/91205
摘要： Certain imidazopyrazines of Formula (I) and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample.
摘要翻译：本文提供了式（I）的某些咪唑并嗪及其药物组合物。治疗患有某些对抑制Syk活性有作用的疾病和病症的患者的方法，其包括给予这些患者一定量的至少一种有效减少疾病或病症体征或症状的化学实体。还提供了用于确定样品中Syk激酶的存在或不存在的方法。

2. 发明申请

US20050110994A1 Method for operating a laser scanning confocal microscope system and a system thereof 失效
公开(公告)号：US20050110994A1
公开(公告)日：2005-05-26
申请号：US11014820
申请日：2004-12-20
申请人： Thomas Foster , David Conover , Chad Biglow , Irene Georgakoudi , Andrey Mezhiba , Soumya Mitra
发明人： Thomas Foster , David Conover , Chad Biglow , Irene Georgakoudi , Andrey Mezhiba , Soumya Mitra
IPC分类号： G02B21/00 , G01N21/64
CPC分类号： G02B21/0076 , G02B21/0024
摘要： A method for operating a confocal microscope system includes deflecting a light beam on a specimen with at least one beam deflection device. The position of the light beam is stepped with at least one beam deflection device across the specimen. A sample of emitted fluorescent light from the specimen is captured in synchronization with each of the stepped positions of the light beam. An image is obtained from the captured samples of emitted fluorescent light.

3. 发明授权

US06859273B2 Method for operating a laser scanning confocal microscope system and a system thereof 失效
标题翻译：操作激光扫描共焦显微镜系统的方法及其系统
公开(公告)号：US06859273B2
公开(公告)日：2005-02-22
申请号：US10202213
申请日：2002-07-23
申请人： Thomas H. Foster , David L. Conover , Chad E. Biglow , Irene Georgakoudi , Andrey Mezhiba , Soumya Mitra
发明人： Thomas H. Foster , David L. Conover , Chad E. Biglow , Irene Georgakoudi , Andrey Mezhiba , Soumya Mitra
IPC分类号： G02B21/00 , G01N21/64
CPC分类号： G02B21/0076 , G02B21/0024
摘要： A method for operating a confocal microscope system includes deflecting a light beam on a specimen with at least one beam deflection device. The position of the light beam is stepped with at least one beam deflection device across the specimen. A sample of emitted fluorescent light from the specimen is captured in synchronization with each of the stepped positions of the light beam. An image is obtained from the captured samples of emitted fluorescent light.
摘要翻译：用于操作共聚焦显微镜系统的方法包括用至少一个光束偏转装置将光束偏转到样本上。光束的位置与跨越样本的至少一个光束偏转装置是阶梯式的。与光束的每个阶梯位置同步捕获来自样品的发射荧光的样品。从所捕获的发射的荧光样品获得图像。

4. 发明授权

US06956647B2 Method for operating a laser scanning confocal microscope system and a system thereof 失效
公开(公告)号：US06956647B2
公开(公告)日：2005-10-18
申请号：US11014820
申请日：2004-12-20
申请人： Thomas H. Foster , David L. Conover , Chad E. Biglow , Irene Georgakoudi , Andrey Mezhiba , Soumya Mitra
发明人： Thomas H. Foster , David L. Conover , Chad E. Biglow , Irene Georgakoudi , Andrey Mezhiba , Soumya Mitra
IPC分类号： G02B21/00 , G01N21/64
CPC分类号： G02B21/0076 , G02B21/0024
摘要： A method for operating a confocal microscope system includes deflecting a light beam on a specimen with at least one beam deflection device. The position of the light beam is stepped with at least one beam deflection device across the specimen. A sample of emitted fluorescent light from the specimen is captured in synchronization with each of the stepped positions of the light beam. An image is obtained from the captured samples of emitted fluorescent light.

5. 发明授权

US08879743B1 Ear models with microphones for psychoacoustic imagery 有权
标题翻译：具有心理声学图像麦克风的耳机型号
公开(公告)号：US08879743B1
公开(公告)日：2014-11-04
申请号：US13309012
申请日：2011-12-01
申请人： Soumya Mitra
发明人： Soumya Mitra
IPC分类号： H04R5/00
CPC分类号： H04R1/342 , H04R5/027
摘要： A compact portable stereo microphone apparatus can acquire three dimensional immersive sounds which can then be recorded and played back in a standard audio recording device. The apparatus includes two elastomer fabricated simplified human ear elements (ear models) fitted at the ends of a cylindrical cavity of a microphone enclosure. The ear models may be protected against physical damage by end grills. A circuit board, microphone cable interface, power indicator, power switch and batteries may be located in the lower shell of the enclosure. A handle may serve as the hand grip for the microphone as well as a battery cover.
摘要翻译：紧凑型便携式立体声麦克风装置可以获取三维沉浸式声音，然后可以在标准音频记录装置中记录和重放。该装置包括装配在麦克风外壳的圆柱形腔的端部的两个弹性体制造的简化人耳元件（耳型）。可以通过末端烤架来保护耳朵模型免受物理伤害。电路板，麦克风电缆接口，电源指示灯，电源开关和电池可能位于外壳的下壳体中。手柄可以用作麦克风的手柄以及电池盖。

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