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1. 发明申请

US20100048561A1 QUINAZOLINES FOR PDK1 INHIBITION 失效
标题翻译：用于PDK1抑制剂的喹唑啉
公开(公告)号：US20100048561A1
公开(公告)日：2010-02-25
申请号：US12295967
申请日：2007-04-05
申请人： Savithri Ramurthy , Xiaodong Lin , Sharadha Subramanian , Alice C. Rico , Xiaojing M. Wang , Rama Jain , Jeremy M. Murray , Steven E. Basham , Robert L. Warne , Wei Shu , Yasheen Zhou , Jeffrey Dove , Mina Aikawa , Payman Amiri , Weibo Wang , Johanna M. Jansen , Allan S. Wagman , Keith B. Pfister , Simon Ng
发明人： Savithri Ramurthy , Xiaodong Lin , Sharadha Subramanian , Alice C. Rico , Xiaojing M. Wang , Rama Jain , Jeremy M. Murray , Steven E. Basham , Robert L. Warne , Wei Shu , Yasheen Zhou , Jeffrey Dove , Mina Aikawa , Payman Amiri , Weibo Wang , Johanna M. Jansen , Allan S. Wagman , Keith B. Pfister , Simon Ng
IPC分类号： A61K31/517 , C07D401/12 , C07D401/14 , C07D239/84 , C07D413/14 , A61K31/5377 , A61P35/00
CPC分类号： C07D239/94 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/10 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/06 , C07D417/14 , C07D451/06 , C07D453/02
摘要： The invention provides quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.
摘要翻译：本发明提供作为PDK1抑制剂的喹唑啉化合物。还提供了包含该化合物的药物组合物，以及用化合物或组合物治疗增殖性疾病如癌症的方法。

2. 发明授权

US07932262B2 Quinazolines for PDK1 inhibition 失效
标题翻译：喹唑啉用于PDK1抑制
公开(公告)号：US07932262B2
公开(公告)日：2011-04-26
申请号：US12295967
申请日：2007-04-05
申请人： Savithri Ramurthy , Xiaodong Lin , Sharadha Subramanian , Alice Rico , Xiaojong M. Wang , Rama Jain , Jeremy M. Murray , Stephen E. Basham , Robert L. Warne , Wei Shu , Yasheen Zhou , Jeffrey Dove , Mina Aikawa , Payman Amiri , Weibo Wang , Johanna M. Jansen , Allan S. Wagman , Keith B. Pfister , Simon Ng
发明人： Savithri Ramurthy , Xiaodong Lin , Sharadha Subramanian , Alice Rico , Xiaojong M. Wang , Rama Jain , Jeremy M. Murray , Stephen E. Basham , Robert L. Warne , Wei Shu , Yasheen Zhou , Jeffrey Dove , Mina Aikawa , Payman Amiri , Weibo Wang , Johanna M. Jansen , Allan S. Wagman , Keith B. Pfister , Simon Ng
IPC分类号： A61K31/517
CPC分类号： C07D239/94 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/10 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/06 , C07D417/14 , C07D451/06 , C07D453/02
摘要： The invention provides quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.
摘要翻译：本发明提供作为PDK1抑制剂的喹唑啉化合物。还提供了包含该化合物的药物组合物，以及用化合物或组合物治疗增殖性疾病如癌症的方法。

3. 发明申请

US20100216767A1 QUINAZOLINES FOR PDK1 INHIBITION 审中-公开
标题翻译：用于PDK1抑制剂的喹唑啉
公开(公告)号：US20100216767A1
公开(公告)日：2010-08-26
申请号：US12448390
申请日：2007-12-20
申请人： Mina Aikawa , Payman Amiri , Steven Bashman , Jeffrey Dove , Rama Jain , Xiaodong Lin , Jeremy Murray , Savithri Ramurthy , Alice Rico , Wei Shu , Sharadha Subramanian , Xiaojing Michael Wang , Robert L. Warne , Yasheen Zhou
发明人： Mina Aikawa , Payman Amiri , Steven Bashman , Jeffrey Dove , Rama Jain , Xiaodong Lin , Jeremy Murray , Savithri Ramurthy , Alice Rico , Wei Shu , Sharadha Subramanian , Xiaojing Michael Wang , Robert L. Warne , Yasheen Zhou
IPC分类号： A61K31/337 , C07D239/84 , A61K31/517 , C07D401/12 , A61K31/496 , C07D403/10 , C07D413/10 , A61K31/5377 , C07D413/14 , C07D403/12 , A61P35/00
CPC分类号： C07D239/84 , C07D401/08 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D411/04 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/14
摘要： The invention provides novel compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.
摘要翻译：本发明提供了作为PDK1抑制剂的新型化合物。还提供了包含该化合物的药物组合物，以及用化合物或组合物治疗增殖性疾病如癌症的方法。

4. 发明申请

US20070076436A1 Backlight module having improved light utilization ratio and liquid crystal having same 审中-公开
标题翻译：具有提高的光利用率的背光模块和具有其的液晶
公开(公告)号：US20070076436A1
公开(公告)日：2007-04-05
申请号：US11541226
申请日：2006-09-29
申请人： Xiao-Ping Ma , Wei Shu
发明人： Xiao-Ping Ma , Wei Shu
IPC分类号： F21V19/00
CPC分类号： G02B6/002 , G02B6/0071 , G02B6/0091
摘要： An exemplary backlight module (3) includes a light guide plate (31), a light source (32) located adjacent to the light guide plate and a fixing member (33) located adjacent to a corner of the light guide plate. The light source includes a corner portion. The fixing member includes a channel (332) fixedly receiving the corner portion of the light source, and a light transmission cutout (334) defined through an inner wall thereof. The light transmission cutout communicates with the channel. Light beams emitting from the corner portion of the light source can enter the light guide plate via the light transmission structure. Therefore, the backlight module has a high light utilization ratio and a uniform brightness distribution.
摘要翻译：示例性背光模块（3）包括导光板（31），邻近导光板定位的光源（32）和邻近导光板的角部定位的固定构件（33）。光源包括角部。固定构件包括固定地容纳光源的角部的通道（332）和通过其内壁限定的光传输切口（334）。光传输切断部与通道通信。从光源的角部发射的光束可以经由透光结构进入导光板。因此，背光模块具有高的光利用率和均匀的亮度分布。

5. 发明申请

US20060227261A1 Light guide plate and backlight module using the same 审中-公开
标题翻译：导光板和背光模组使用相同
公开(公告)号：US20060227261A1
公开(公告)日：2006-10-12
申请号：US11401195
申请日：2006-04-10
申请人： Wei Shu
发明人： Wei Shu
IPC分类号： G02F1/1335
CPC分类号： G02B6/0071 , G02B6/0091
摘要： A light guide plate (20) for use in a backlight assembly includes a base plate (21) and a fastener (210). The base plate includes a light output surface (212), at least two light input surfaces (211) adjacent to the light output surface, and a bottom surface (215) opposite to the at least light output surface. The fastener is integrated with the base plate and is located at a corner of the base plate between the at least two light input surfaces for stably held light sources therein. This helps prevent the light source from being displaced when an LCD device employing the light guide plate is subjected to vibration or shock.
摘要翻译：用于背光组件的导光板（20）包括基板（21）和紧固件（210）。基板包括光输出表面（212），与光输出表面相邻的至少两个光输入表面（211）和与至少光输出表面相对的底表面（215）。紧固件与基板一体化，并且位于至少两个光输入表面之间的基板的角落处，用于其中稳定保持的光源。这有助于防止当采用导光板的LCD装置受到振动或冲击时光源发生位移。

6. 发明申请

US20110240453A1 KEY MODULE FOR PORTABLE DEVICES 有权
标题翻译：便携式设备的关键模块
公开(公告)号：US20110240453A1
公开(公告)日：2011-10-06
申请号：US13157301
申请日：2011-06-09
申请人： Wei Shu
发明人： Wei Shu
IPC分类号： H01H13/76 , H01H13/14
CPC分类号： H01H13/84 , H01H2209/002 , H01H2217/012 , H01H2217/036
摘要： A key module for portable devices includes a PCB having at least one pair of high resistance film and welding point, a rubber key having a protruded key head, and a set of upper case and bottom case. The rubber key has two conducting carbon arcs opposite to the at least one pair of high resistance film on a concave backside thereof. A top of the head portion has a concave on a middle portion thereof and two protrusions on right and left ends thereof for specific input functions. The upper case has at least one through hole for revealing the concave and the protrusions of the head portion while the rubber key and the PCB are covered by the upper and bottom cases.
摘要翻译：用于便携式设备的关键模块包括具有至少一对高电阻膜和焊接点的PCB，具有突出键头的橡胶键和一组上壳体和底壳。橡胶键具有两个导电碳弧，与其凹面背面上的至少一对高电阻膜相对。头部的顶部在其中间部分具有凹部，在其右侧和左侧具有两个突出部，用于特定的输入功能。上壳体具有至少一个通孔，用于在橡胶键和PCB被上壳体和底壳体覆盖的同时露出头部的凹部和突起。

7. 发明授权

US07223902B1 Method of producing recombinant Aspergillus niger β-glucosidase and an aroma spreading plant 失效
标题翻译：生产重组黑曲霉β-葡萄糖苷酶和芳香蔓延植物的方法
公开(公告)号：US07223902B1
公开(公告)日：2007-05-29
申请号：US10130150
申请日：2000-11-15
申请人： Wei Shu , Ira Marton , Daniel L. Siegel , Bravdo Ben-Ami , Mara Dekel , Oded Shoseyov
发明人： Wei Shu , Ira Marton , Daniel L. Siegel , Bravdo Ben-Ami , Mara Dekel , Oded Shoseyov
IPC分类号： C12N15/82
CPC分类号： C12N15/8242 , C12N9/2445 , C12N15/8243 , C12P19/14 , C12Y302/01021 , Y02E50/16 , Y02E50/17
摘要： The invention provides a method of producing a recombinant polypeptide having β-glucosidase enzymatic activity, a polynucleotide encoding the polypeptide, nucleic acid constructs carrying the polynucleotide, transformed cells, such as yeast cells, and transgenic organisms expressing the polynucleotide. The invention provides various uses of the polypeptide, the polynucleotide, cells and/or organisms, including producing a recombinant polypeptide having β-glucosidase enzymatic activity, increasing the level of aromatic compounds in alcoholic beverages, as well as other fermentation products of plant material, hydrolyzing cellobiose and thus increasing the level of fermentable glucose, increasing the production of alcohol; such as ethanol from plant material, increasing the aroma released from a plant, or a plant, product, and hydrolysis or transglycosylation of glycosides.
摘要翻译：本发明提供了生产具有β-葡糖苷酶酶活性的重组多肽的方法，编码多肽的多核苷酸，携带多核苷酸的核酸构建体，转化细胞如酵母细胞，以及表达多核苷酸的转基因生物。本发明提供多肽，多核苷酸，细胞和/或生物的各种用途，包括产生具有β-葡糖苷酶酶活性的重组多肽，增加酒精饮料中芳族化合物的含量以及植物材料的其它发酵产物，水解纤维二糖，从而增加可发酵葡萄糖的水平，增加酒精的产生; 例如来自植物材料的乙醇，增加从植物释放的香气，或植物，产品和糖苷的水解或转糖基化。

8. 发明公开

US20230316972A1 NEAR-EYE DISPLAY DEVICE 审中-公开
公开(公告)号：US20230316972A1
公开(公告)日：2023-10-05
申请号：US17950092
申请日：2022-09-21
申请人： Wei Shu
发明人： Wei Shu , Manli Guo , Xiaoguang He
IPC分类号： G09G3/02 , G02B26/10
CPC分类号： G09G3/02 , G02B26/10
摘要： The present disclosure provides a near-eye display device. The near-eye display device includes: a light source module and an optical module, where the light source module includes multiple laser image sources, which are vertical-cavity surface-emitting laser (VCSEL) image sources or collimated light image sources; the light source module is configured to: perform digital-to-analog (D-A) conversion on an image signal and load the image signal into the laser image sources, such that the laser image sources emit red, green, and blue (RGB) laser beams; the optical module includes a compound eye control chip and a projection element array; the projection element array includes multiple projection elements, which are arranged on the compound eye control chip according to a preset arrangement pattern; and the optical module is configured to: control the projection elements to rotate within a preset angle through the compound eye control chip.

9. 发明申请

US20230063932A1 FOLDING OPTICAL WAVEGUIDE NEAR-TO-EYE DISPLAY DEVICE 有权
公开(公告)号：US20230063932A1
公开(公告)日：2023-03-02
申请号：US17570359
申请日：2022-01-06
申请人： Wei Shu
发明人： Wei Shu , Manli Guo , Xiaoguang He
IPC分类号： G02B27/01 , G02B27/09
摘要： Disclosed herein is a folding optical waveguide near-to-eye display device, including: an image source (111), a prism (121) with a cylindrical surface, a curved lens (131), a prism (141), and a prism group (151) connected by two or more prisms glued together in sequence, where a prism surface of the prism (121) is partially or completely a cylindrical surface, the cylindrical surface faces the image source (111), the prism (121) is connected to the prism (141) through a prism surface other than the cylindrical surface to form a first gluing surface, the prism (121) is connected with an opposite surface of a curved surface of the curved lens (131) through another prism surface other than the cylindrical surface to form a second gluing surface, and the prism (141) and the prisms of the prism group (151) are glued and connected in sequence.

10. 发明申请

US20080123271A1 Flat panel display with sandwiched grounding member 审中-公开
标题翻译：带夹层接地构件的平板显示器
公开(公告)号：US20080123271A1
公开(公告)日：2008-05-29
申请号：US11821728
申请日：2007-06-25
申请人： Wei Shu
发明人： Wei Shu
IPC分类号： H05K5/02
CPC分类号： H05K5/02
摘要： An exemplary flat panel display (1) includes a top bezel (10), a display module (12), a bottom tray (14), and a grounding member (16). The top bezel includes a first protrusion (105). The bottom tray is engaged to the top bezel, and includes a second protrusion corresponding to the first protrusion. The display module is substantially accommodated by the bottom tray. A portion of the grounding member is held between the first protrusion and the second protrusion.
摘要翻译：示例性的平板显示器（1）包括顶部挡板（10），显示模块（12），底部托盘（14）和接地构件（16）。顶部挡板包括第一突起（105）。底部托盘接合到顶部挡板，并且包括对应于第一突起的第二突出部。显示模块基本上由底部托盘容纳。接地构件的一部分保持在第一突起和第二突起之间。

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