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1. 发明申请

US20050113387A1 Pyrazine derivatives and pharmaceutical use thereof 失效
标题翻译：吡嗪衍生物及其药物用途
公开(公告)号：US20050113387A1
公开(公告)日：2005-05-26
申请号：US10972340
申请日：2004-10-26
申请人： Satoshi Yonishi , Satoshi Aoki , Yuji Matsushima , Atsushi Akahane
发明人： Satoshi Yonishi , Satoshi Aoki , Yuji Matsushima , Atsushi Akahane
IPC分类号： A61K31/4965 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/14 , A61K31/497 , C07D43/02 , C07D43/14
CPC分类号： C07D401/04 , C07D401/14 , C07D405/14 , C07D409/14
摘要： A pyrazine derivative of the following formula (I): or a salt thereof. The pyrazine compound (I) and a salt thereof of the present invention are adenosine antagonists and are useful for the prevention and/or treatment of depression, dementia (e.g. Alzheimer's disease, cerebrovascular dementia, dementia accompanying Parkinson's disease, etc.), Parkinson's disease, anxiety, pain, cerebrovascular disease (e.g. stroke, etc.), heart failure and the like.
摘要翻译：下式（I）的吡嗪衍生物或其盐。本发明的吡嗪化合物（I）及其盐是腺苷拮抗剂，可用于预防和/或治疗抑郁症，痴呆（例如阿尔茨海默氏病，脑血管性痴呆，伴有帕金森病的痴呆等），帕金森病，焦虑，疼痛，脑血管疾病（例如中风等），心力衰竭等。

2. 发明授权

US07407961B2 Pyrazine derivatives and pharmaceutical use thereof 失效
标题翻译：吡嗪衍生物及其药物用途
公开(公告)号：US07407961B2
公开(公告)日：2008-08-05
申请号：US10972340
申请日：2004-10-26
申请人： Satoshi Yonishi , Satoshi Aoki , Yuji Matsushima , Atsushi Akahane
发明人： Satoshi Yonishi , Satoshi Aoki , Yuji Matsushima , Atsushi Akahane
IPC分类号： A61K31/4965 , C07D401/00 , C07D403/00 , C07D405/00 , C07D409/00 , C07D411/00 , C07D413/00 , C07D417/00 , C07D419/00
CPC分类号： C07D401/04 , C07D401/14 , C07D405/14 , C07D409/14
摘要： A pyrazine derivative of the following formula (I): or a salt thereof. The pyrazine compound (I) and a salt thereof of the present invention are adenosine antagonists and are useful for the prevention and/or treatment of depression, dementia (e.g. Alzheimer's disease, cerebrovascular dementia, dementia accompanying Parkinson's disease, etc.), Parkinson's disease, anxiety, pain, cerebrovascular disease (e.g. stroke, etc.), heart failure and the like.
摘要翻译：下式（I）的吡嗪衍生物或其盐。本发明的吡嗪化合物（I）及其盐是腺苷拮抗剂，可用于预防和/或治疗抑郁症，痴呆（例如阿尔茨海默氏病，脑血管性痴呆，伴有帕金森病的痴呆等），帕金森病，焦虑，疼痛，脑血管疾病（例如中风等），心力衰竭等。

3. 发明授权

US10686946B2 Intermediary device, device monitoring system, and intermediation method 有权
公开(公告)号：US10686946B2
公开(公告)日：2020-06-16
申请号：US16268770
申请日：2019-02-06
申请人： Satoshi Aoki
发明人： Satoshi Aoki
IPC分类号： G06F3/12 , H04N1/00 , H04N1/32 , H04L29/08
摘要： An intermediary device includes circuitry to: transmit, to a server, device information on a device to be monitored acquired from the device via a network; monitor a state of another intermediary device, the another intermediary device being configured to acquire from another device to be monitored device information on the another device and transmit the acquired device information to the information processor; and take over monitoring of the another device, which the another intermediary device kept monitoring, based on setting information for monitoring the another device monitored by the another intermediary device, when the state of the another intermediary device indicates that the another intermediary device has an abnormality.

4. 发明授权

US09268577B2 Information processing apparatus 有权
标题翻译：信息处理装置
公开(公告)号：US09268577B2
公开(公告)日：2016-02-23
申请号：US13973046
申请日：2013-08-22
申请人： Tamon Sadasue , Satoshi Mori , Naoya Ohashi , Satoshi Aoki , Naoya Morita
发明人： Tamon Sadasue , Satoshi Mori , Naoya Ohashi , Satoshi Aoki , Naoya Morita
IPC分类号： G06F9/44 , G06F12/02
CPC分类号： G06F9/4401 , G06F9/448 , G06F12/0284
摘要： An information processing apparatus includes a processor that executes an instruction stored in a fixed address area in a storage part; the storage part that stores a first startup program and a second startup program, contents of the second startup program being different at least partially from those of the first startup program; and an address conversion part that, when the processor carries out a predetermined startup different from an ordinary startup that is carried out at a time of starting power supply to the information processing apparatus, converts an address included in a read instruction issued by the processor indicating a storage area that stores the first startup program into an address indicating an other storage area that stores the second startup program, and sends the converted address to the storage part.
摘要翻译：信息处理装置包括执行存储在存储部分中的固定地址区域中的指令的处理器; 存储部分，其存储第一启动程序和第二启动程序，所述第二启动程序的内容至少部分地不同于所述第一启动程序的内容; 以及地址转换部分，当处理器执行不同于在向信息处理设备开始供电时执行的普通启动的预定启动时，转换由处理器发出的读取指令中包括的地址，指示存储区域，其将第一启动程序存储到指示存储第二启动程序的其他存储区域的地址中，并将转换的地址发送到存储部。

5. 发明授权

US08901130B2 Low hygroscopic aripiprazole drug substance and processes for the preparation 有权
标题翻译：低吸湿性阿立哌唑药物及其制备方法
公开(公告)号：US08901130B2
公开(公告)日：2014-12-02
申请号：US13476758
申请日：2012-05-21
申请人： Takuji Bando , Satoshi Aoki , Junichi Kawasaki , Makoto Ishigami , Youichi Taniguchi , Tsuyoshi Yabuuchi , Kiyoshi Fujimoto , Yoshihiro Nishioka , Noriyuki Kobayashi , Tsutomu Fujimura , Masanori Takahashi , Kaoru Abe , Tomonori Nakagawa , Koichi Shinhama , Naoto Utsumi , Michiaki Tominaga , Yoshihiro Ooi , Shohei Yamada , Kenji Tomikawa
发明人： Takuji Bando , Satoshi Aoki , Junichi Kawasaki , Makoto Ishigami , Youichi Taniguchi , Tsuyoshi Yabuuchi , Kiyoshi Fujimoto , Yoshihiro Nishioka , Noriyuki Kobayashi , Tsutomu Fujimura , Masanori Takahashi , Kaoru Abe , Tomonori Nakagawa , Koichi Shinhama , Naoto Utsumi , Michiaki Tominaga , Yoshihiro Ooi , Shohei Yamada , Kenji Tomikawa
IPC分类号： A61K31/497 , C07D401/14 , C07D215/227
CPC分类号： C07D215/227 , C07B2200/13 , C07D215/22 , Y10T428/2982
摘要： The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the anhydrous Aripiprazole crystals is stored for an extended period.
摘要翻译：本发明提供低吸湿形式的阿立哌唑及其制备方法，即使当含有无水阿立哌唑晶体的药物制剂长时间储存时，其也不会转化为水合物或丧失其原始溶解度。

6. 发明申请

US20140228567A1 Method for Producing Fine Particles of Aripiprazole Anhydride Crystals B 有权
标题翻译：生产阿立哌唑酸酐晶体微粒的方法B
公开(公告)号：US20140228567A1
公开(公告)日：2014-08-14
申请号：US14128305
申请日：2012-06-29
申请人： Takuji Bando , Katsuhiko Yano , Makoto Fukana , Satoshi Aoki
发明人： Takuji Bando , Katsuhiko Yano , Makoto Fukana , Satoshi Aoki
IPC分类号： C07D215/22
CPC分类号： C07D215/22
摘要： The present invention provides a novel method for producing fine particles of aripiprazole anhydride crystals B. The method for producing fine particles of aripiprazole anhydride crystals B comprises the steps of: (1) heating and dissolving crude aripiprazole in a lower alcohol, and subsequently cooling the resulting mixture to precipitate crystals to obtain crystals of aripiprazole lower alcohol solvate; (2) subjecting the crystals of aripiprazole lower alcohol solvate to wet-milling in the form of a slurry containing the lower alcohol; and (3) subjecting the dispersion of the wet-milled crystals to solid-liquid separation to obtain the crystals, and heating the crystals.
摘要翻译：本发明提供了一种制备阿立哌唑酐晶体B的微粒的新方法。阿立哌唑酐晶体B的微粒的制造方法包括以下步骤：（1）将阿立哌唑粗制物加热溶解在低级醇中，得到的混合物沉淀出晶体，得到阿立哌唑低级醇溶剂化物晶体; （2）使阿立哌唑低级醇溶剂化物的晶体以含有低级醇的浆液的形式进行湿磨; 和（3）将经湿磨的晶体的分散液进行固液分离，得到晶体，并加热晶体。

7. 发明申请

US20140026226A1 DEVICE, METHOD AND PROGRAM FOR PREVENTING INFORMATION LEAKAGE 有权
标题翻译：用于防止信息泄漏的设备，方法和程序
公开(公告)号：US20140026226A1
公开(公告)日：2014-01-23
申请号：US14007175
申请日：2012-03-16
申请人： Satoshi Aoki , Manabu Kameda
发明人： Satoshi Aoki , Manabu Kameda
IPC分类号： G06F21/62
CPC分类号： G06F21/6245 , G06F21/51 , G06F21/6263 , H04L67/02
摘要： Provided is a device for preventing information leakage including: a storage unit that stores message time, request source information, and request destination information in relation to each information requesting message; a unit that suspends a response message containing personal information in response messages in response to the information requesting messages, for a predetermined suspended time from a message time of the corresponding information requesting message; a unit that counts the number of information requesting messages transmitted from the same request source to the same destination and corresponding to the suspended response message on the basis of information stored in the storage unit; and a unit that, in the case where the counted number of the information requesting messages exceeds a predetermined threshold value, applies a protection process to the suspended response message so that the personal information contained in the suspended response message is not received by the request source.
摘要翻译：提供了一种用于防止信息泄露的装置，包括：存储单元，其存储关于每个信息请求消息的消息时间，请求源信息和请求目的地信息; 响应于所述信息请求消息而在响应消息中包含个人信息的响应消息的单元，从相应信息请求消息的消息时间起预定的暂停时间; 基于存储在存储单元中的信息，计数从相同请求源发送到相同目的地并对应于暂停的响应消息的信息请求数量的单元; 以及在所述信息请求消息的所计数的数量超过预定阈值的情况下，对所述暂停的响应消息应用保护处理，使得所述暂停的响应消息中包含的个人信息未被所述请求源接收的单元。

8. 发明授权

US08593087B2 Magnetic pole position estimation method for AC synchronous motor 有权
标题翻译：交流同步电机磁极位置估算方法
公开(公告)号：US08593087B2
公开(公告)日：2013-11-26
申请号：US12678888
申请日：2008-11-14
申请人： Kei Terada , Satoshi Aoki
发明人： Kei Terada , Satoshi Aoki
IPC分类号： H02P21/00
CPC分类号： H02P21/0035 , H02P21/18 , H02P21/22 , H02P21/24
摘要： If there is static friction, the magnetic pole position estimation is completed at the time when error torque used for magnetic pole position estimation becomes less than the friction, so that there remains magnetic pole error. A problem has been that when the error torque becomes less than a forward static friction, there remains a positive magnetic pole deviation and when the error torque becomes less than a backward static friction, there remains a negative magnetic pole deviation. By shifting in the negative direction and the positive direction initial values for estimating a magnetic pole error in operation sets, a true pole-error estimation value is estimated in the use of a pole-error estimation value having a positive magnetic pole error obtained by the positive shift operation and a negative one obtained by the negative shift operation, which can reduce estimation error due to the static friction.
摘要翻译：如果存在静摩擦，磁极位置估计在用于磁极位置估计的误差转矩小于摩擦时完成磁极位置估计，从而保持磁极误差。一个问题是，当误差转矩小于正向静摩擦时，仍然存在正磁极偏移，当误差转矩小于反向静摩擦时，仍然存在负磁极偏差。通过在负方向和正方向上移动用于估计操作组中的磁极误差的初始值，在使用由具有正磁极误差的极性误差估计值得到的极性误差估计值时，估计真正的极点误差估计值正偏移操作和通过负移位操作获得的负移动操作，这可以减少由于静摩擦引起的估计误差。

9. 发明申请

US20110212973A1 CARBAMATE COMPOUND OR SALT THEREOF 审中-公开
标题翻译：碳酸盐化合物或其盐
公开(公告)号：US20110212973A1
公开(公告)日：2011-09-01
申请号：US13126980
申请日：2009-11-05
申请人： Takahiro Ishii , Takashi Sugane , Ryosuke Munakata , Satoshi Aoki , Masahide Higaki , Akiyoshi Someya
发明人： Takahiro Ishii , Takashi Sugane , Ryosuke Munakata , Satoshi Aoki , Masahide Higaki , Akiyoshi Someya
IPC分类号： A61K31/496 , C07D405/14 , C07D417/14 , C07D409/14 , C07D413/14 , C07D401/14 , A61P13/00 , A61P13/10 , A61P13/08
CPC分类号： A61K31/496 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/04 , C07D417/12
摘要： [Problems] A compound useful as an active ingredient for a pharmaceutical composition for treating FAAH-related diseases is provided.[Means for Solution] The present inventors have made extensive studies on compounds having an FAAH inhibitory activity, and as a result, have found that a piperazine-1-carboxylate compound, in which benzimidazol-2-ylcarbonyl, benzofuran-2-ylcarbonyl or the like binds to the 4-position of the piperazine, has an excellent FAAH inhibitory activity and further has an action to increase the effective bladder capacity, an action to ameliorate sleep disorders, an anti-diuretic action, and an analgesic activity on lower urinary tract pain including bladder pain and the like, thereby completed the present invention. The carbamate compound of the present invention has an excellent FAAH inhibitory activity and can be used as an agent for preventing and/or treating FAAH-related diseases, particularly nocturia, interstitial cystitis, painful bladder syndrome, or chronic non-bacterial prostatitis/chronic pelvic pain syndrome.
摘要翻译： [问题]提供了用作治疗FAAH相关疾病的药物组合物的活性成分的化合物。 [解决方案]本发明人对具有FAAH抑制活性的化合物进行了广泛的研究，结果发现了哌嗪-1-羧酸酯化合物，其中苯并咪唑-2-基羰基，苯并呋喃-2-基羰基或类似物与哌嗪的4-位结合，具有优异的FAAH抑制活性，并且还具有增加膀胱有效能力的作用，改善睡眠障碍的作用，抗利尿作用和对下尿路的止痛活性包括膀胱疼痛等的道痛，从而完成了本发明。本发明的氨基甲酸酯化合物具有优异的FAAH抑制活性，可用作预防和/或治疗FAAH相关疾病，特别是夜尿症，间质性膀胱炎，疼痛膀胱综合征或慢性非细菌性前列腺炎/慢性骨盆疼痛综合征。

10. 发明申请

US20080283389A1 Method for Manufacturing Chalcopyrite Thin-Film Solar Cell 有权
标题翻译：制造黄铜矿薄膜太阳能电池的方法
公开(公告)号：US20080283389A1
公开(公告)日：2008-11-20
申请号：US11568776
申请日：2005-04-12
申请人： Satoshi Aoki
发明人： Satoshi Aoki
IPC分类号： C23C14/00
CPC分类号： H01L31/0322 , Y02E10/541 , Y02P70/521
摘要： A method for fabricating a chalcopyrite-type thin film solar cell includes a first step of forming onto a Mo electrode layer 2 a precursor including an In metal layer and a Cu—Ga alloy layer by sputtering, a second step of attaching an alkali-metal solution onto the precursor, a selenization step of subjecting the substrate 1 which has undergone both the first and the second steps to a selenization treatment, and a transparent electrode forming step of depositing an optically transparent conductive layer. As the alkali-metal solution, an aqueous solution of an alkali metal compound, such as sodium tetraborate, sodium sulfide, and sodium aluminum sulfate, can be used.
摘要翻译：制造黄铜矿型薄膜太阳能电池的方法包括：第一步骤，通过溅射在Mo电极层2上形成包含In金属层和Cu-Ga合金层的前体，第二步是将碱金属将上述第一和第二步骤的基板1进行硒化处理的硒化工序，以及沉积光学透明导电层的透明电极形成步骤。作为碱金属溶液，可以使用四硼酸钠，硫化钠，硫酸铝钠等碱金属化合物的水溶液。

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