专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20050105666A1 Production of thorium-229 审中-公开
标题翻译：生产钍-229
公开(公告)号：US20050105666A1
公开(公告)日：2005-05-19
申请号：US10938044
申请日：2004-09-10
申请人： Saed Mirzadeh , Marc Garland
发明人： Saed Mirzadeh , Marc Garland
IPC分类号： G21G1/06 , G21G1/10 , G21G4/08
CPC分类号： G21G1/10 , G21G1/06 , G21G4/08
摘要： A method for producing 229Th includes the steps of providing 226Ra as a target material, and bombarding the target material with alpha particles, helium-3, or neutrons to form 229Th. When neutrons are used, the neutrons preferably include an epithermal neutron flux of at least 1×1013 n s−1·cm−2. 228Ra can also be bombarded with thermal and/or energetic neutrons to result in a neutron capture reaction to form 229Th. Using 230Th as a target material, 229Th can be formed using neutron, gamma ray, proton or deuteron bombardment.
摘要翻译：一种生产<！ - SIPO “>”的方法包括以下步骤：提供作为目标材料的Ra，并用α粒子，氦-3或中子轰击靶物质， SUP> 229 Th。当使用中子时，中子优选包括至少1×10 13 s -1的范围的超热中子通量。也可以用热和/或能量中子轰击Ra以产生中子俘获反应以形成第229号。使用<230> Th Th作为靶材料，可以使用中子，γ射线，质子或氘核轰击形成Th2 Th。

2. 发明申请

US20070098130A1 Production of thorium-229 from thorium-230 审中-公开
标题翻译：从钍-230生产钍-229
公开(公告)号：US20070098130A1
公开(公告)日：2007-05-03
申请号：US11507152
申请日：2006-08-21
申请人： Saed Mirzadeh , Marc Garland
发明人： Saed Mirzadeh , Marc Garland
IPC分类号： G21G1/00
CPC分类号： G21G1/10 , G21G1/06 , G21G4/08
摘要： A method for producing 229Th uses 230Th as a target material. 229Th can be formed from 230Th using energetic particles, including neutron, gamma ray, proton or deuteron bombardment.
摘要翻译：用于生产^{229 Th的方法使用“230”Th作为目标材料。可以使用高能粒子（包括中子，γ射线，质子或氘核轰击）从230形成Th。}

3. 发明授权

US07914766B1 Inorganic resins for clinical use of 213Bi generators 有权
标题翻译：无机树脂临床使用213Bi发电机
公开(公告)号：US07914766B1
公开(公告)日：2011-03-29
申请号：US10860520
申请日：2004-06-03
申请人： David W. DePaoli , Michael Z. Hu , Saed Mirzadeh , John W. Clavier
发明人： David W. DePaoli , Michael Z. Hu , Saed Mirzadeh , John W. Clavier
IPC分类号： A61K51/00 , A61M36/14
CPC分类号： B01J39/17
摘要： Applicant's invention is a radionuclide generator resin material for radiochemical separation of daughter radionuclides, particularly 213Bi, from a solution of parental radionuclides, the resin material capable of providing clinical quantities of 213Bi of at least 20-mCi, wherein the resin material comprises a silica-based structure having at least one bifunctional ligand covalently attached to the surface of the silica-based structure. The bifunctional ligand comprises a chemical group having desirable surface functionality to enable the covalent attachment of the bifunctional ligand thereon the surface of the structure and the bifunctional ligand further comprises a second chemical group capable of binding and holding the parental radionuclides on the resin material while allowing the daughter radionuclides to elute off the resin material. The bifunctional ligand has a carbon chain with a limited number of carbons to maintain radiation stability of the resin material.
摘要翻译：申请人的发明是一种放射性核素发生器树脂材料，用于从母体放射性核素的溶液中放大化学分离子放射性核素，特别是213Bi，所述树脂材料能够提供临界量为213Bi的至少20-mCi，其中树脂材料包含二氧化硅 - 具有至少一个共价连接到二氧化硅基结构的表面上的双官能配体。双功能配体包含具有所需表面官能团的化学基团，以使双功能配体在其结构表面上共价连接，而双功能配体还包含能够将亲本放射性核素结合并保持在树脂材料上的第二化学基团，同时允许女儿放射性核素洗脱树脂材料。双功能配体具有碳链数量有限的碳链，以保持树脂材料的辐射稳定性。

4. 发明申请

US20110065816A1 INORGANIC RESINS FOR CLINICAL USE OF 213BI GENERATORS 有权
标题翻译： 213BI发生器临床使用的无机树脂
公开(公告)号：US20110065816A1
公开(公告)日：2011-03-17
申请号：US10860520
申请日：2004-06-03
申请人： David W. DePaoli , Michael Z. Hu , Saed Mirzadeh , John W. Clavier
发明人： David W. DePaoli , Michael Z. Hu , Saed Mirzadeh , John W. Clavier
IPC分类号： B01J39/00
CPC分类号： B01J39/17
摘要： Applicant's invention is a radionuclide generator resin material for radiochemical separation of daughter radionuclides, particularly 213Bi, from a solution of parental radionuclides, the resin material capable of providing clinical quantities of 213Bi of at least 20-mCi, wherein the resin material comprises a silica-based structure having at least one bifunctional ligand covalently attached to the surface of the silica-based structure. The bifunctional ligand comprises a chemical group having desirable surface functionality to enable the covalent attachment of the bifunctional ligand thereon the surface of the structure and the bifunctional ligand further comprises a second chemical group capable of binding and holding the parental radionuclides on the resin material while allowing the daughter radionuclides to elute off the resin material. The bifunctional ligand has a carbon chain with a limited number of carbons to maintain radiation stability of the resin material.
摘要翻译：申请人的发明是一种放射性核素发生器树脂材料，用于从母体放射性核素的溶液中放大化学分离子放射性核素，特别是213Bi，所述树脂材料能够提供临界量为213Bi的至少20-mCi，其中树脂材料包含二氧化硅 - 具有至少一个共价连接到二氧化硅基结构的表面上的双官能配体。双功能配体包含具有所需表面官能团的化学基团，以使双功能配体在其结构表面上共价连接，而双功能配体还包含能够将亲本放射性核素结合并保持在树脂材料上的第二化学基团，同时允许女儿放射性核素洗脱树脂材料。双功能配体具有碳链数量有限的碳链，以保持树脂材料的辐射稳定性。

5. 发明授权

US06751280B2 Method of preparing high specific activity platinum-195m 失效
标题翻译：制备高比活性铂-195μm的方法
公开(公告)号：US06751280B2
公开(公告)日：2004-06-15
申请号：US10217088
申请日：2002-08-12
申请人： Saed Mirzadeh , Miting Du , Arnold L. Beets , Furn F. Knapp, Jr.
发明人： Saed Mirzadeh , Miting Du , Arnold L. Beets , Furn F. Knapp, Jr.
IPC分类号： G21G106
CPC分类号： G21G1/02 , G21G1/06
摘要： A method of preparing high-specific-activity 195mPt includes the steps of: exposing 193Ir to a flux of neutrons sufficient to convert a portion of the 193Ir to 195mPt to form an irradiated material; dissolving the irradiated material to form an intermediate solution comprising Ir and Pt; and separating the Pt from the Ir by cation exchange chromatography to produce 195mPt.
摘要翻译：制备高比活性<195m> Pt的方法包括以下步骤：将193将Ir暴露于足以将一部分<193> Ir转化成<195m> Pt的中子，以形成辐射材料; 溶解被照射的材料以形成包含Ir和Pt的中间溶液; 并通过阳离子交换层析从Pt中分离出Pt以产生<195m> Pt。

6. 发明授权

US5774782A Technetium-99m generator system 失效
标题翻译：锝-99m发电机系统
公开(公告)号：US5774782A
公开(公告)日：1998-06-30
申请号：US619376
申请日：1996-05-22
申请人： Saed Mirzadeh , Furn F. Knapp, Jr. , Emory D. Collins
发明人： Saed Mirzadeh , Furn F. Knapp, Jr. , Emory D. Collins
IPC分类号： G21G4/08 , A61K51/12 , B01D15/04 , B01D59/24 , B01J41/04 , C01G99/00 , C07F13/00 , C01G57/00
CPC分类号： A61K51/1282 , G21G2001/0036
摘要： A .sup.99 Mo/.sup.99m Tc generator system includes a sorbent column loaded with a composition containing .sup.99 Mo. The sorbent column has an effluent end in fluid communication with an anion-exchange column for concentrating .sup.99m Tc eluted from the sorbent column. A method of preparing a concentrated solution of .sup.99m Tc includes the general steps of: a. providing a sorbent column loaded with a composition containing .sup.99 Mo, the sorbent column having an effluent end in fluid communication with an anion-exchange column; b. eluting the sorbent column with a salt solution to elute .sup.99m Tc from the sorbent and to trap and concentrate the eluted .sup.99m Tc on the ion-exchange column; and c. eluting the concentrated .sup.99m Tc from the ion-exchange column with a solution comprising a reductive complexing agent.
摘要翻译： 99Mo / 99mTc发生器系统包括装载有含有99Mo的组合物的吸附塔。吸附塔具有与阴离子交换柱流体连通的流出物末端，用于浓缩从吸附塔洗脱的99mTc。制备99mTc浓缩溶液的方法包括以下步骤：a。提供负载有含有99Mo的组合物的吸附剂柱，吸附塔具有与阴离子交换柱流体连通的流出物末端; b。用盐溶液洗脱吸附剂柱，从吸附剂中洗脱99mTc，并将洗脱的99mTc捕集并浓缩在离子交换柱上; 和c。用含有还原络合剂的溶液从离子交换柱洗脱浓缩的99mTc。

7. 发明授权

US07852975B2 Production of thorium-229 using helium nuclei 有权
标题翻译：使用氦核生产钍-229
公开(公告)号：US07852975B2
公开(公告)日：2010-12-14
申请号：US12422679
申请日：2009-04-13
申请人： Saed Mirzadeh , Marc Alan Garland
发明人： Saed Mirzadeh , Marc Alan Garland
IPC分类号： G21G1/12
CPC分类号： G21G1/10 , G21G1/06 , G21G4/08
摘要： A method for producing 229Th includes the steps of providing 226Ra as a target material, and bombarding the target material with alpha particles, helium-3, or neutrons to form 229Th. When neutrons are used, the neutrons preferably include an epithermal neutron flux of at least 1×1013 n s−1·cm−2. 228Ra can also be bombarded with thermal and/or energetic neutrons to result in a neutron capture reaction to form 229Th. Using 230Th as a target material, 229Th can be formed using neutron, gamma ray, proton or deuteron bombardment.
摘要翻译：制备229Th的方法包括以下步骤：提供226Ra作为目标材料，并用α粒子，氦-3或中子轰击靶物质形成229Th。当使用中子时，中子优选包括至少1×1013n s-1·cm-2的超热中子通量。 228Ra也可以用热和/或能量中子轰击，导致中子俘获反应形成229Th。使用230Th作为目标材料，可以使用中子，γ射线，质子或氘核轰击形成229Th。

8. 发明授权

US06716353B1 Method for preparing high specific activity 177Lu 失效
标题翻译：高比活度制备方法177Lu
公开(公告)号：US06716353B1
公开(公告)日：2004-04-06
申请号：US10283608
申请日：2002-10-30
申请人： Saed Mirzadeh , Miting Du , Arnold L. Beets , Furn F. Knapp, Jr.
发明人： Saed Mirzadeh , Miting Du , Arnold L. Beets , Furn F. Knapp, Jr.
IPC分类号： B01D1508
CPC分类号： G21G1/02 , B01D15/08 , B01D15/426 , B01J20/265 , B01J20/285 , C22B3/24 , C22B3/42 , C22B59/00 , C22B61/00 , G21F9/12 , G21F9/125 , G21G1/00 , Y02P10/234
摘要： A method of separating lutetium from a solution containing Lu and Yb, particularly reactor-produced 177Lu and 177Yb, includes the steps of: providing a chromatographic separation apparatus containing LN resin; loading the apparatus with a solution containing Lu and Yb; and eluting the apparatus to chromatographically separate the Lu and the Yb in order to produce high-specific-activity 177Yb.
摘要翻译：从含有Lu和Yb的溶液中分离出镥的方法，特别是反应器生产的Lu和177 Yb的方法包括以下步骤：提供含有LN树脂的色谱分离装置; 用含有Lu和Yb的溶液装载设备; 并将该装置洗脱以色谱分离Lu和Yb，以产生高比活度的<177> Yb。

9. 发明申请

US20080060998A1 Reactor Production and Purification of Promethium-147 有权
标题翻译： ium-147的反应器生产和纯化
公开(公告)号：US20080060998A1
公开(公告)日：2008-03-13
申请号：US11530207
申请日：2006-09-08
申请人： Furn F. Knapp , Rose A Boll , Saed Mirzadeh
发明人： Furn F. Knapp , Rose A Boll , Saed Mirzadeh
IPC分类号： C01G56/00 , B01D15/08
CPC分类号： C01F17/0006 , B01D15/08 , B01J20/286 , G21G1/001 , G21G1/06 , G21G2001/0094
摘要： A method of producing and purifying promethium-147 including the steps of: irradiating a target material including neodymium-146 with neutrons to produce promethium-147 within the irradiated target material; dissolving the irradiated target material to form an acidic solution; loading the acidic solution onto a chromatographic separation apparatus containing HDEHP; and eluting the apparatus to chromatographically separate the promethium-147 from the neodymium-146.
摘要翻译：一种生产和纯化ium-147的方法，包括以下步骤：用辐射的目标材料照射包含钕-146的靶材料与中子，以产生ium-147; 溶解被照射的靶材以形成酸性溶液; 将酸性溶液装载到含有HDEHP的色谱分离装置上; 并将该装置洗脱，以将ium -147与钕-146进行色谱分离。

10. 发明授权

US06804319B1 High specific activity platinum-195m 失效
标题翻译：高比活性铂-195m
公开(公告)号：US06804319B1
公开(公告)日：2004-10-12
申请号：US10718235
申请日：2003-11-20
申请人： Saed Mirzadeh , Miting Du , Arnold L. Beets , Furn F. Knapp, Jr.
发明人： Saed Mirzadeh , Miting Du , Arnold L. Beets , Furn F. Knapp, Jr.
IPC分类号： G21G106
CPC分类号： G21G1/02 , G21G1/06
摘要： A new composition of matter includes 195mPt characterized by a specific activity of at least 30 mCi/mg Pt, generally made by method that includes the steps of: exposing 193Ir to a flux of neutrons sufficient to convert a portion of the 193Ir to 195mPt to form an irradiated material; dissolving the irradiated material to form an intermediate solution comprising Ir and Pt; and separating the Pt from the Ir by cation exchange chromatography to produce 195mPt.
摘要翻译：一种新的物质组合物包括特征在于具有至少30mCi / mg Pt的比活性的<195m> Pt，通常由方法制成，方法包括以下步骤：将193将Ir暴露于足以转化一部分 <193> Ir至<195m> Pt以形成辐射材料; 溶解被照射的材料以形成包含Ir和Pt的中间溶液; 并通过阳离子交换层析从Pt中分离出Pt以产生<195m> Pt。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式