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1. 发明授权

US4138553A 3-Methylene cephalosporanic acid derivatives and process for preparation thereof 失效
标题翻译： 3-亚甲基头孢菌酸衍生物及其制备方法
公开(公告)号：US4138553A
公开(公告)日：1979-02-06
申请号：US841321
申请日：1977-10-11
申请人： Sachio Ishimoto , Hisao Yamaguchi , Yoshinori Kato , Takeo Oba , Kenji Ozawa , Yataro Ichikawa , Koji Nakagawa , Hideki Tsuruta
发明人： Sachio Ishimoto , Hisao Yamaguchi , Yoshinori Kato , Takeo Oba , Kenji Ozawa , Yataro Ichikawa , Koji Nakagawa , Hideki Tsuruta
IPC分类号： C07D499/00 , C07D501/10 , C07D501/02
CPC分类号： C07D499/00 , Y02P20/55
摘要： Novel substituted hydrazide derivatives of 7-(substituted)amino-3-methylene-cepham-4-carboxylic acids expressed by the formula ##STR1## wherein R.sub.1 represents alkyl containing at least 3 carbon atoms, cycloalkyl, or optionally substituted aryl, and one of R.sub.2 and R.sub.3 represents hydrogen with the other being hydrogen or the same as R.sub.1 ; or R.sub.1 and R.sub.2 form a heterocyclic ring optionally through a hetero atom together with the attached nitrogen and R.sub.3 represents hydrogen atom; and Z.sub.1 represents amino or protected amino; and acid addition salts thereof, which are useful as intermediates for synthesizing cephalosporin antibiotics. These compounds can be prepared in high yields from the corresponding substituted hydrazide derivatives of 6-substituted amino-1-oxide-2, 2-dimethyl-penam-3-carboxylic acids, which are readily available at low costs, by heating them in the presence of a thermal rearrangement promotor such as organic sulfonic acids and optionally in the further presence of a tertiary nitrogen-containing cyclic compound, followed if desired by splitting off the amino-protecting group and converting the product to acid addition salts.
摘要翻译：由式“IMAGE”表示的7-（取代的）氨基-3-亚甲基 - 头孢烯-4-羧酸的新型取代的酰肼衍生物，其中R 1表示含有至少3个碳原子的烷基，环烷基或任选取代的芳基， R2和R3代表氢，另一个是氢或与R1相同; 或R 1和R 2与所连接的氮一起任选地通过杂原子形成杂环，并且R 3表示氢原子; Z1表示氨基或被保护的氨基; 其酸加成盐，其可用作合成头孢菌素抗生素的中间体。这些化合物可以以相当于6-取代的氨基-1-氧化物-2,2-二甲基 - 对甲苯磺酸的取代的酰肼衍生物的高收率制备，它们以低成本容易获得，通过在存在热重排促进剂如有机磺酸，并且任选地在另外存在叔氮气环状化合物的情况下，如果需要的话，分解氨基保护基并将产物转化成酸加成盐。

2. 发明授权

US4605645A 5-fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof 失效
标题翻译： 5-氟-2'-脱氧尿苷衍生物及其制备方法
公开(公告)号：US4605645A
公开(公告)日：1986-08-12
申请号：US448087
申请日：1982-12-09
申请人： Kenzo Watanabe , Yoshinori Kato , Masahiko Saito , Takeo Oba , Hisashi Fukushima , Takeshi Hara
发明人： Kenzo Watanabe , Yoshinori Kato , Masahiko Saito , Takeo Oba , Hisashi Fukushima , Takeshi Hara
IPC分类号： C07H19/10 , C07H15/12 , C07H17/00
CPC分类号： C07H19/10 , Y02P20/55
摘要： 5-fluoro-2'-deoxyuridine derivatives expressed by general formula (1) and their pharmacologically permissible salts ##STR1## wherein A indicates a saturated or unsaturated divalent aliphatic hydrocarbon group having 1 to 30 carbon atoms; the letter n indicates 0 or 1, and when n is 0, it indicates that Y is directly bound to an oxygen atom; Y represents a hydrogen atom, phenyl group, or substituted phenyl group; however, when Y is a hydrogen atom, n is 1; R indicates a hydrogen atom or alcohol-protecting group.These compounds have a very strong antitumor activity.
摘要翻译：由通式（1）表示的5-氟-2'-脱氧尿苷衍生物及其药理学允许的盐（1）其中A表示具有1至30个碳原子的饱和或不饱和的二价脂族烃基; 字母n表示0或1，当n为0时，表示Y与氧原子直接结合; Y表示氢原子，苯基或取代的苯基; 然而，当Y为氢原子时，n为1; R表示氢原子或醇保护基。这些化合物具有非常强的抗肿瘤活性。

3. 发明申请

US20140154185A1 USE OF NON-LABELED SUGARS AND DETECTION BY MRI FOR ASSESSING TISSUE PERFUSION AND METABOLISM 有权
标题翻译：使用非标签糖和MRI检测组织吸收和代谢
公开(公告)号：US20140154185A1
公开(公告)日：2014-06-05
申请号：US13994600
申请日：2011-12-14
申请人： Peter C. Van Zijl , Dmitri Artemov , Kannie Wai Yan Chan , Yoshinori Kato , Michael T. McMahon , Guanshu Liu
发明人： Peter C. Van Zijl , Dmitri Artemov , Kannie Wai Yan Chan , Yoshinori Kato , Michael T. McMahon , Guanshu Liu
IPC分类号： A61K49/10 , A61B5/055
CPC分类号： A61K49/10 , A61B5/026 , A61B5/055 , A61B5/14532 , A61B5/14539 , A61B5/4866 , A61B5/74 , A61M5/142 , G01R33/5605
摘要： A method for magnetic resonance (MR) imaging or spectroscopy on a MR scanner to detect tissue physiological parameters in one or more tissue areas in a human or non-human subject includes administering to the subject a contrast enhancing physiologically tolerable amount of a sugar that is non-labeled, subjecting the subject to an MR procedure capable of generating MR signals encoding at least one tissue area in the subject in which the sugar either passes or is taken up, detecting a temporal variation in the MR signals in the at least one tissue area after the administering the sugar, determining at least one tissue-related parameter from the temporal variation, and ascertaining whether the at least one tissue-related parameter is abnormal.
摘要翻译：在MR扫描仪上用于检测人或非人受试者的一个或多个组织区域中的组织生理参数的磁共振（MR）成像或光谱学方法包括向对象施用增强生理上可耐受量的糖未标记的，对受试者进行能够产生MR信号的MR程序的MR程序，所述MR信号编码所述受试者中经过或被摄取的受试者中的至少一个组织区域，检测所述至少一个组织中的MR信号的时间变化施用糖后的区域，根据时间变化确定至少一个组织相关参数，以及确定至少一个组织相关参数是否异常。

4. 发明申请

US20140023986A1 MOTORIZED SYRINGE FOR USE WITH TWO TYPES OF DENTAL ANESTHETIC SOLUTION-CONTAINING CARTRIDGES 有权
标题翻译：使用两种类型的牙科麻醉解决方案的电动搅拌器
公开(公告)号：US20140023986A1
公开(公告)日：2014-01-23
申请号：US14009752
申请日：2011-04-12
申请人： Fumio Tanaka , Mitsuhiro Haraguchi , Mutsumi Shibuya , Renji Hayashi , Yoshinori Kato
发明人： Fumio Tanaka , Mitsuhiro Haraguchi , Yoshihiko Kawasaki , Mutsumi Shibuya , Renji Hayashi , Yoshinori Kato
IPC分类号： A61M5/24 , A61M5/315
CPC分类号： A61M5/31583 , A61C19/08 , A61M5/1452 , A61M5/20 , A61M5/24 , A61M5/315 , A61M2005/2411
摘要： A motorized syringe for use with two types of dental anesthetic solution-filled cartridges, having a plunger plug in the 1.8 ml cartridge pushed by a push rod by a length required to push a plunger plug in the 1.0 ml cartridge. The syringe includes a cartridge holder for use with 1.0 ml and 1.8 ml cartridges, the push rod having a 1.0 ml position and a 1.8 ml position drawn back from the 1.0 ml position so that push rod movement can end at a common terminal position for both, a sleeve adapted to receive the push rod rear end when pushed back from the common terminal position, and to be not interfered with by the push rod's rear end when it is in the 1.0 ml position, the sleeve being pushed rearward with the push rod's rear end when pushed back to the 1.8 ml position.
摘要翻译：一种用于两种类型的牙科麻醉剂溶液填充的药筒的电动注射器，其具有由推杆推动的1.8ml药筒中的柱塞塞，所述长度需要将柱塞塞推到1.0ml药筒中。注射器包括用于1.0ml和1.8ml药筒的药筒保持器，推杆具有1.0ml的位置和从1.0ml位置拉回的1.8ml位置，使得推杆运动可以在两个共同的终端位置终止，当从公共端子位置推回时适于接收推杆后端的套筒，当其处于1.0ml位置时不受推杆后端的干扰，套筒被推杆向后推动后推回到1.8毫升的位置。

5. 发明申请

US20130258006A1 INK CARTRIDGE 有权
标题翻译：墨盒
公开(公告)号：US20130258006A1
公开(公告)日：2013-10-03
申请号：US13804578
申请日：2013-03-14
申请人： Yoshinori Kato
发明人： Yoshinori Kato
IPC分类号： B41J2/175
CPC分类号： B41J2/17503 , B41J2/17566 , B41J2002/17586
摘要： An ink cartridge includes a storage portion, a housing, a movable member, a support portion, and an intermediate member. The storage portion has flexibility and is configured to store ink. The housing that covers the storage portion and at least a central portion of the storage portion is fixed to the housing. The movable member contacts with the storage portion in the housing, and is rotatable in accordance with changes in a position of contact with the storage portion. The support portion is provided in the housing and includes a pair of engagement portions. The pair of engagement portions are disposed at an interval therebetween and rotatably support the movable member. The intermediate member is disposed between the movable member and the storage portion.
摘要翻译：墨盒包括存储部分，壳体，可移动部件，支撑部分和中间部件。存储部分具有柔性并被配置为存储墨水。覆盖存储部分和存储部分的至少中心部分的壳体固定到壳体。可移动构件与壳体中的存储部分接触，并且可以根据与存储部分的接触位置的变化而旋转。支撑部设置在壳体中，并且包括一对接合部。一对接合部分间隔设置并可旋转地支撑可动件。中间构件设置在可动构件和存储部之间。

6. 发明授权

US08465122B2 Liquid jetting apparatus 有权
标题翻译：液体喷射装置
公开(公告)号：US08465122B2
公开(公告)日：2013-06-18
申请号：US13075003
申请日：2011-03-29
申请人： Yoshinori Kato
发明人： Yoshinori Kato
IPC分类号： B41J2/165
CPC分类号： B41J2/16538 , B41J2/16541
摘要： A liquid jetting apparatus includes: a liquid jetting head which has a liquid jetting surface being formed with a nozzle to jet a liquid to a recording medium; a wiper which makes contact with the liquid jetting surface to bend and wipes away the liquid adhered to the liquid jetting surface; a movement mechanism which moves the wiper relative to the liquid jetting surface in a wipe direction along the liquid jetting surface; a movement controller which stops the wiper, which has wiped away the liquid adhered to the liquid jetting surface by moving relative to the liquid jetting surface in the wipe direction, at a predetermined stop position; and a separating mechanism which separates the wiper stopped by the movement controller from the liquid jetting surface in a separating direction intersecting the liquid jetting surface.
摘要翻译：液体喷射装置包括：液体喷射头，其具有形成有喷嘴以将液体喷射到记录介质的喷嘴表面; 与液体喷射表面接触以使附着在液体喷射表面上的液体弯曲并擦拭的擦拭器; 运动机构，沿着液体喷射表面沿着擦拭方向移动刮水器相对于液体喷射表面; 移动控制器，其在预定的停止位置处停止刮水器，其通过在擦拭方向上相对于液体喷射表面移动而擦去附着到液体喷射表面的液体; 以及分离机构，其在与液体喷射表面相交的分离方向上将由运动控制器停止的刮水器与液体喷射表面分离。

7. 发明申请

US20130119115A1 FRICTION STIR WELDING DEVICE 有权
标题翻译：摩擦焊接装置
公开(公告)号：US20130119115A1
公开(公告)日：2013-05-16
申请号：US13812642
申请日：2011-05-27
申请人： Yoshinori Kato , Satoshi Furutate , Toshiyuki Kinoshita
发明人： Yoshinori Kato , Satoshi Furutate , Toshiyuki Kinoshita
IPC分类号： B23K20/12
CPC分类号： B23K20/1255 , B23K20/126
摘要： A friction stir welding device (1) includes a workpiece disposition unit (2) at which workpieces (W) is disposed, a main body section (3) disposed at a surface (W4) of the workpieces (W) disposed at the workpiece disposition unit (2), a tool holding unit (4) formed in the main body section (3) to enable advance and retreat in a direction facing the workpieces (Z), which is a direction approaching and separating from the workpieces (W) disposed at the workpiece disposition unit (2), and configured to hold a tool (100), and a support medium (5) formed to satisfy a predetermined relative positional relationship in the direction facing the workpieces (Z) with respect to a first shoulder surface of the tool (100) attached to the tool holding unit (4) and configured to support the tool holding unit (4) on the surface (W4) of the workpieces (W) disposed at the workpieces disposition unit (2).
摘要翻译：摩擦搅拌焊接装置（1）包括设置有工件（W）的工件配置单元（2），设置在设置在工件配置处的工件（W）的表面（W4）上的主体部分（3）单元（2），形成在主体部分（3）中的工具保持单元（4），以能够在面向工件（Z）的方向上前进和后退，工件（Z）是与所设置的工件（W）接近和分离的方向在所述工件配置单元（2）处，构造成保持工具（100），以及支撑介质（5），所述支撑介质形成为在与所述工件（Z）相对于第一台肩表面的方向上满足预定的相对位置关系所述工具（100）安装在所述工具保持单元（4）上并被构造成将所述工具保持单元（4）支撑在设置在所述工件配置单元（2）的所述工件（W）的表面（W4）上。

8. 发明授权

US08091612B2 Method for manufacturing clad material and equipment for manufacturing the same 有权
标题翻译：复合材料的制造方法及其制造方法
公开(公告)号：US08091612B2
公开(公告)日：2012-01-10
申请号：US12095983
申请日：2006-12-07
申请人： Masayuki Takada , Yasuhiro Nishioka , Tomohiro Nishimura , Kenji Tokuda , Toshiki Ueda , Makoto Morishita , Takashi Inaba , Akihiro Tsuruno , Yoshinori Kato , Fumihiro Koshigoe , Masaki Tanigawa , Naoki Sakashita , Kenji Harada , Jitsuto Shikata , Masanori Ikeda
发明人： Masayuki Takada , Yasuhiro Nishioka , Tomohiro Nishimura , Kenji Tokuda , Toshiki Ueda , Makoto Morishita , Takashi Inaba , Akihiro Tsuruno , Yoshinori Kato , Fumihiro Koshigoe , Masaki Tanigawa , Naoki Sakashita , Kenji Harada , Jitsuto Shikata , Masanori Ikeda
IPC分类号： B22D11/00 , B22D11/12 , B22D11/126 , B22D19/16
CPC分类号： B32B3/00 , B22D11/007 , B23K20/04 , B23K35/22 , B23K35/40 , B23K2101/16 , B32B15/016 , C22C21/00 , C22F1/04 , Y10T428/12736 , Y10T428/12764 , Y10T428/12993
摘要： A method for manufacturing a clad material composed of a core material and one or more skin materials which are superposed on either one or both faces of the core material, includes a clad material preparation process where an ingot for core material is manufactured by melting and casting a metal, and an ingot for skin material is manufactured by melting and casting a different metal for skin material, without hot rolling. The ingot for skin material is superposed as a skin material at a predetermined position of either one or both faces of the ingot for core material and the superposed material is hot-rolled to manufacture a clad material.
摘要翻译：一种由芯材构成的复合材料和叠层在芯材的一面或两面上的一种或多种表皮材料的包覆材料的制造方法，包括：通过熔融铸造制造芯材用铸锭的复合材料制备方法金属和用于表皮材料的锭是通过熔化和铸造用于表皮材料的不同金属而不进行热轧而制造的。将表皮材料锭作为表皮材料叠置在用于芯材的锭的一个或两个面的预定位置，并且叠加的材料被热轧以制造包覆材料。

9. 发明申请

US20090051732A1 INKJET RECORDING APPARATUS, METHOD OF CLEANING A RECORDING HEAD, AND A COMPUTER READABLE MEDIUM ENCODING THE METHOD 有权
标题翻译：喷墨记录装置，清洁记录头的方法和编写方法的计算机可读介质
公开(公告)号：US20090051732A1
公开(公告)日：2009-02-26
申请号：US12196870
申请日：2008-08-22
申请人： Yoshinori Kato , Nobuo Hiraki , Tomohisa Higuchi
发明人： Yoshinori Kato , Nobuo Hiraki , Tomohisa Higuchi
IPC分类号： B41J2/165
CPC分类号： B41J2/16538
摘要： An inkjet recording apparatus, method and computer readable medium are provided. The inkjet recording apparatus includes a recording head comprising a nozzle formation surface having a plurality of ink discharging nozzles formed thereon; a wiper which has elasticity and wipes the nozzle formation surface by pressingly contacting against the nozzle formation surface of the recording head; and a moving unit which moves at least one of the recording head and the wiper to wipe the nozzle formation surface at a first relative speed and moves the at least one of the recording head and the wiper to separate from each other at a second relative speed, which is less than the first relative speed. The method includes moving at least one of the inkjet recording head and the wiper relative to each other so that the wiper wipes the nozzle formation surface at a first relative speed; and separating the wiper from the inkjet recording head at a second relative speed, which is less than the first relative speed.
摘要翻译：提供喷墨记录装置，方法和计算机可读介质。喷墨记录装置包括：记录头，包括形成在其上的多个喷墨嘴的喷嘴形成表面; 擦拭器，其通过与记录头的喷嘴形成面压接而具有弹性并擦拭喷嘴形成面; 以及移动单元，其移动所述记录头和所述擦拭器中的至少一个以以第一相对速度擦拭所述喷嘴形成表面，并且使所述记录头和所述擦拭器中的至少一个以第二相对速度彼此分离，小于第一相对速度。该方法包括相对于彼此移动喷墨记录头和擦拭器中的至少一个，使得擦拭器以第一相对速度擦拭喷嘴形成表面; 并且以比第一相对速度小的第二相对速度将刮水器与喷墨记录头分离。

10. 发明授权

US07232904B2 Crystal of arylethenesulfonamide derivative and preparation process thereof 失效
标题翻译：芳基磺酰胺衍生物的晶体及其制备方法
公开(公告)号：US07232904B2
公开(公告)日：2007-06-19
申请号：US10484836
申请日：2002-07-25
申请人： Yoshinori Kato , Hironori Harada , Masahiro Kurotani , Haruhiko Toda , Kenichirou Sakamoto
发明人： Yoshinori Kato , Hironori Harada , Masahiro Kurotani , Haruhiko Toda , Kenichirou Sakamoto
IPC分类号： C07D239/48 , C07D239/54
CPC分类号： C07D239/52
摘要： Novel crystals of a potassium salt of (E)-N-[6-methoxy-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl]-2-phenylethenesulfonamide, a preparation process thereof, and novel solvates of (E)-N-[6-methoxy-5-(2-ethoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl]-2-phenylethenesulfonamide.
摘要翻译：（E）-N- [6-甲氧基-5-（2-甲氧基苯氧基）-2-（嘧啶-2-基）嘧啶-4-基] -2-苯基亚磺酰胺的钾盐的新晶体，其制备方法（E）-N- [6-甲氧基-5-（2-乙氧基苯氧基）-2-（嘧啶-2-基）嘧啶-4-基] -2-苯基乙烯基磺酰胺的新溶剂合物。

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