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1. 发明申请

WO2012051126A2 ANTI-INFLAMMATORY MACROLIDES 审中-公开
标题翻译：抗炎剂MACROLIDES
公开(公告)号：WO2012051126A2
公开(公告)日：2012-04-19
申请号：PCT/US2011/055657
申请日：2011-10-10
申请人： SYNOVO GMBH , BURNET, Michael , GUSE, Jan-Hinrich , BAEUERLEIN, Christiane , EGGERS, Mary
发明人： BURNET, Michael , GUSE, Jan-Hinrich , BAEUERLEIN, Christiane , EGGERS, Mary
IPC分类号： C07H17/08 , C07D413/12 , A61K31/7048 , A61P29/00
CPC分类号： C07H17/08
摘要： The invention provides novel compounds and compositions and methods for making and using the compounds and compositions.
摘要翻译：本发明提供了新型化合物和组合物以及制备和使用该化合物和组合物的方法。

2. 发明申请

WO2018161039A1 NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS 审中-公开
公开(公告)号：WO2018161039A1
公开(公告)日：2018-09-07
申请号：PCT/US2018/020769
申请日：2018-03-02
申请人： SYNOVO GMBH , PIETRZIK, Nikolas , BURNET, Michael, W. , BAEUERLEIN, Christiane , EGGERS, Mary , GUSE, Jan-hinrich , HAHN, Ulrike , STRASS, Simon
发明人： PIETRZIK, Nikolas , BURNET, Michael, W. , BAEUERLEIN, Christiane , EGGERS, Mary , GUSE, Jan-hinrich , HAHN, Ulrike , STRASS, Simon
IPC分类号： A61K47/50 , A61K47/54 , C07H17/00 , C07H17/02 , C07H17/08
摘要： Lysosomally accumulated substances that release a nitroxy group, or a short chain fatty acid or a product of anaerobic metabolism or a thiol or a sulfide often from an ester or similar labile linkage have anti-inflammatory, anti-cancer and anti-bacterial activity. They are useful in treating infectious, inflammatory and malignant disease.

3. 发明公开

EP3589327A1 NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS 审中-公开
公开(公告)号：EP3589327A1
公开(公告)日：2020-01-08
申请号：EP18761736.0
申请日：2018-03-02
申请人： Synovo GmbH , Burnet, Michael W.
发明人： PIETRZIK, Nikolas , BURNET, Michael, W. , BAEUERLEIN, Christiane , EGGERS, Mary , GUSE, Jan-Hinrich , HAHN, Ulrike , STRASS, Simon
IPC分类号： A61K47/50 , A61K47/54 , C07H17/00 , C07H17/02 , C07H17/08

4. 发明公开

EP2625185A2 ANTI-INFLAMMATORY MACROLIDES 审中-公开
标题翻译：抗炎大环内酯类
公开(公告)号：EP2625185A2
公开(公告)日：2013-08-14
申请号：EP11833216.2
申请日：2011-10-10
申请人： Synovo GmbH , Burnet, Michael
发明人： BURNET, Michael , GUSE, Jan-Hinrich , BAEUERLEIN, Christiane , EGGERS, Mary
IPC分类号： C07H17/08 , C07D413/12 , A61K31/7048 , A61P29/00
CPC分类号： C07H17/08
摘要： The invention provides novel compounds and compositions and methods for making and using the compounds and compositions.

5. 发明申请

WO2017212345A3 DETECTING MICROBIAL INFECTION IN WOUNDS 审中-公开
标题翻译：检测伤口微生物感染
公开(公告)号：WO2017212345A3
公开(公告)日：2017-12-14
申请号：PCT/IB2017/001182
申请日：2017-03-30
申请人： SYNOVO GMBH
发明人： GUSE, Jan Hinrich , REISSER, Martin , PIETRZIK, Nikolas , BAEUERLEIN, Christiane
IPC分类号： G01N33/52 , G01N21/78 , G01N33/68
摘要： The disclosed technology relates to chemical entities for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. The disclosed technology further relates to methods of using these compositions, kits and systems in diagnostic assays, and in the diagnosis and/or detection of chronic or infected wounds based on enzymatic action on specific moieties and/or reaction sites. The disclosed technology additionally relates to detection of pathogenic, e.g., bacterial and/or viral substances, such as enzymes and substrates, at the wound situs. Additional disclosure relates to methods of characterizing wounds based on expression of a plurality of markers and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.
摘要翻译：所公开的技术涉及用于检测伤口（例如慢性伤口或感染伤口）的化学实体，所述伤口包括组合物，基质，试剂盒，敷料和制品以及含有这些化合物的系统。所公开的技术还涉及在诊断测定中使用这些组合物，试剂盒和系统以及基于对特定部分和/或反应位点的酶作用诊断和/或检测慢性或感染伤口的方法。所公开的技术另外涉及在伤口部位检测病原体，例如细菌和/或病毒物质，例如酶和底物。另外的公开内容涉及基于多个标记物的表达来表征伤口并使用这些信息来治疗，处理和追踪患有慢性或感染伤口的患者的方法。

6. 发明申请

WO2017212345A2 DETECTING MICROBIAL INFECTION IN WOUNDS 审中-公开
公开(公告)号：WO2017212345A2
公开(公告)日：2017-12-14
申请号：PCT/IB2017/001182
申请日：2017-03-30
申请人： SYNOVO GMBH
发明人： GUSE, Jan Hinrich , REISSER, Martin , PIETRZIK, Nikolas , BAEUERLEIN, Christiane
IPC分类号： C12Q1/34
摘要： The disclosed technology relates to chemical entities for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. The disclosed technology further relates to methods of using these compositions, kits and systems in diagnostic assays, and in the diagnosis and/or detection of chronic or infected wounds based on enzymatic action on specific moieties and/or reaction sites. The disclosed technology additionally relates to detection of pathogenic, e.g., bacterial and/or viral substances, such as enzymes and substrates, at the wound situs. Additional disclosure relates to methods of characterizing wounds based on expression of a plurality of markers and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.

7. 发明公开

EP3436821A2 DETECTING MICROBIAL INFECTION IN WOUNDS 审中-公开
公开(公告)号：EP3436821A2
公开(公告)日：2019-02-06
申请号：EP17787245.4
申请日：2017-03-30
申请人： Synovo GmbH
发明人： GUSE, Jan Hinrich , REISSER, Martin , PIETRZIK, Nikolas , BAEUERLEIN, Christiane
IPC分类号： G01N33/52 , G01N21/78 , G01N33/68

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