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1. 发明申请

WO2017009691A1 SYSTEMS AND METHODS FOR ADAPTIVE MULTI-RESOLUTION MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：用于自适应多分辨率磁共振成像的系统和方法
公开(公告)号：WO2017009691A1
公开(公告)日：2017-01-19
申请号：PCT/IB2015/055407
申请日：2015-07-16
申请人： SYNAPTIVE MEDICAL (BARBADOS) INC.
发明人： PIRON, Cameron , STAINSBY, Jeff , HARRIS, Chad , BEATTY, Phillip
IPC分类号： A61B5/055
CPC分类号： A61B5/055 , A61B5/035 , A61B5/037 , G01R33/543 , G01R33/561
摘要： Systems and methods for adaptive, multi- resolution magnetic resonance imaging ("MRI"], in which an MRI scan prescription is adaptively changed to acquire high-quality data from select regions-of-interest ("ROI"] in a larger field-of-view ("FOV"), are provided. The higher quality data can include data representing higher spatial resolution, higher signal-to-noise ratio ("SNR"], increased diffusion encoding via repeated acquisition with a larger number of diffusion-encoding directions, and so on. A composite image can be generated that displays the higher quality images of the ROIs overlaid on the larger FOV.
摘要翻译：用于自适应多分辨率磁共振成像（“MRI”）的系统和方法，其中自动改变MRI扫描处方以从较大场域中的选择感兴趣区域（“ROI”）获取高质量数据，视频（“FOV”），更高质量的数据可以包括表示较高的空间分辨率，较高的信噪比（“SNR”）的数据，通过重复采集增加的扩散编码，编码方向等等，可以生成复合图像，显示覆盖在较大FOV上的ROI的较高质量图像。

2. 发明申请

WO2016132176A1 SYSTEMS AND METHODS FOR MEASURING GLOBAL GLYMPHATIC FLOW USING MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：使用磁共振成像测量全球GLYMPHAIC流量的系统和方法
公开(公告)号：WO2016132176A1
公开(公告)日：2016-08-25
申请号：PCT/IB2015/051285
申请日：2015-02-19
申请人： SYNAPTIVE MEDICAL (BARBADOS) INC.
发明人： PIRON, Cameron , STAINSBY, Jeff , HARRIS, Chad
IPC分类号： A61B5/03 , A61B5/055
CPC分类号： A61B5/055 , A61B5/031 , A61B5/032 , A61B5/4058 , A61B5/4076 , A61B5/4809 , A61B2576/00 , G01R33/56341 , G01R33/56366
摘要： Systems and methods for providing quantitative measurements of global glymphatic flow of cerebrospinal fluid ("CSF") using magnetic resonance imaging ("MRI") are described. In general, images are obtained from a subject using flow- sensitive MRI techniques that are designed to be particularly sensitive to the glymphatic flow of CSF. Measures of glymphatic flow can be obtained while the subject is in an awake state and again while the subject is in a sleep state. Based on these two measurements, a biomarker that indicates a neurological state or disease can be generated.
摘要翻译：描述了使用磁共振成像（“MRI”）提供脑脊液（“CSF”）的全局血液流量定量测量的系统和方法。一般来说，使用被设计为对CSF的淋巴管流特别敏感的流敏MRI技术从受试者获得图像。当受试者处于清醒状态时，并且当受试者处于睡眠状态时，可以获得血液流量的测量。基于这两个测量，可以产生指示神经系统状态或疾病的生物标志物。

3. 发明申请

WO2015040473A1 COIL ASSEMBLY FOR MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：用于磁共振成像的线圈组件
公开(公告)号：WO2015040473A1
公开(公告)日：2015-03-26
申请号：PCT/IB2014/001864
申请日：2014-09-17
申请人： SYNAPTIVE MEDICAL (BARBADOS) INC.
发明人： PIRON, Cameron , PANTHER, Alex , THINGVOLD, Sheryl , HARRIS, Chad , STAINSBY, Jeff
IPC分类号： G01R33/341
CPC分类号： G01R33/34053 , A61B5/0042 , A61B5/055 , A61M16/01 , A61M16/08 , G01R33/283 , G01R33/288 , G01R33/30 , G01R33/34046 , G01R33/385 , G01R33/3858
摘要： A magnetic resonance imaging system is provided. The system includes a solenoid magnet configured to generate a static magnetic field and an annular coil assembly housed within at least a portion of the solenoid magnet. The coil assembly includes a gradient coil, wherein the annular coil assembly has an aperture formed therein.
摘要翻译：提供磁共振成像系统。该系统包括构造成产生静磁场的螺线管磁体和容纳在螺线管磁体的至少一部分内的环形线圈组件。线圈组件包括梯度线圈，其中环形线圈组件具有形成在其中的孔。

4. 发明公开

EP3362812A1 MAGNETIC RESONANCE IMAGING SYSTEM CAPABLE OF RAPID FIELD RAMPING 审中-公开
公开(公告)号：EP3362812A1
公开(公告)日：2018-08-22
申请号：EP15906200.9
申请日：2015-10-16
申请人： Synaptive Medical (Barbados) Inc.
发明人： STAINSBY, Jeff , HARRIS, Chad , PANTHER, Alexander , PIRON, Cameron
IPC分类号： G01R33/3815 , H01L39/16
CPC分类号： G01R33/3815 , G01R33/3804 , H01F6/008
摘要： Systems and methods for rapidly ramping the magnetic field of a superconducting magnet, such as a superconducting magnet adapted for use in a magnetic resonance imaging system, are provided. The magnetic field can be rapidly ramped up or down by changing the current density in the superconducting magnet while monitoring and controlling the superconducting magnet's temperature to remain below a transition temperature. A superconducting switch is used to connect the superconducting magnet and a power supply in a connected circuit. The current generated by the power supply is then adjusted to increase or decrease the current density in the superconducting magnet to respectively ramp up or ramp down the magnetic field strength in a controlled manner. The ramp rate at which the magnetic field strength is changed is determined and optimized based on the operating parameters of the superconducting magnet and the current being generated by the power supply.

5. 发明申请

WO2018078428A1 SYSTEM AND METHOD FOR REDUCING PERIPHERAL NERVE STIMULATION AT HIGHER GRADIENT AMPLITUDES AND FASTER GRADIENT SLEW RATES IN MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：用于减少磁共振成像中更高梯度的外周神经刺激和更快的梯度速率的系统和方法
公开(公告)号：WO2018078428A1
公开(公告)日：2018-05-03
申请号：PCT/IB2016/056565
申请日：2016-10-31
申请人： SYNAPTIVE MEDICAL (BARBADOS) INC.
发明人： HARRIS, Chad , BINDSEIL, Geron , HANDLER, William
IPC分类号： G01N27/02 , G01R33/46 , G01R33/465 , G01V3/00 , G01V3/18 , G01R33/34 , G01V1/00 , G01V3/38 , G01V11/00
摘要： Described here are systems and methods for imaging a subject with a magnetic resonance imaging ("MRI") system using magnetic field gradients generated by one or more gradient coils operating with gradient coil settings (e.g., gradient amplitudes, gradient slew rates) above a threshold at which peripheral nerve stimulation ("PNS") is likely to be induced in the subject. A dielectric assembly is positioned adjacent a skin surface of the subject such that the dielectric assembly attenuates the local electric fields induced by the magnetic field gradients, which would be likely to induce PNS when the dielectric assembly is not arranged adjacent the skin surface of the subject. As a result of the dielectric assembly placed adjacent the skin surface of the subject, the gradient coil settings can be increased above the threshold without inducing PNS in the subject.
摘要翻译：这里描述的是用磁共振成像（“MRI”）系统使用由一个或多个梯度线圈产生的磁场梯度对对象进行成像的系统和方法，所述梯度线圈以梯度线圈设置（例如，梯度振幅，梯度转换率）高于可能在受试者中诱发周围神经刺激（“PNS”）的阈值。电介质组件定位在对象的皮肤表面附近，使得电介质组件衰减由磁场梯度引起的局部电场，当电介质组件未被布置为邻近受试者的皮肤表面时，这将很可能诱发PNS 。由于电介质组件放置在受试者的皮肤表面附近，所以梯度线圈设置可以增加到阈值以上而不在受试者中诱发PNS。

6. 发明申请

WO2017064539A1 MAGNETIC RESONANCE IMAGING SYSTEM CAPABLE OF RAPID FIELD RAMPING 审中-公开
标题翻译：磁场共振成像系统可用于快速激励
公开(公告)号：WO2017064539A1
公开(公告)日：2017-04-20
申请号：PCT/IB2015/057979
申请日：2015-10-16
申请人： SYNAPTIVE MEDICAL (BARBADOS) INC.
发明人： STAINSBY, Jeff , HARRIS, Chad , PANTHER, Alexander , PIRON, Cameron
IPC分类号： G01R33/3815 , H01L39/16
CPC分类号： G01R33/3815 , G01R33/3804 , H01F6/008
摘要： Systems and methods for rapidly ramping the magnetic field of a superconducting magnet, such as a superconducting magnet adapted for use in a magnetic resonance imaging system, are provided. The magnetic field can be rapidly ramped up or down by changing the current density in the superconducting magnet while monitoring and controlling the superconducting magnet's temperature to remain below a transition temperature. A superconducting switch is used to connect the superconducting magnet and a power supply in a connected circuit. The current generated by the power supply is then adjusted to increase or decrease the current density in the superconducting magnet to respectively ramp up or ramp down the magnetic field strength in a controlled manner. The ramp rate at which the magnetic field strength is changed is determined and optimized based on the operating parameters of the superconducting magnet and the current being generated by the power supply.
摘要翻译：提供了用于快速提升超导磁体（例如适用于磁共振成像系统的超导磁体）的磁场的系统和方法。通过改变超导磁体的电流密度，磁场可以迅速上升或下降，同时监测和控制超导磁体的温度保持低于转变温度。超导开关用于连接超导磁体和连接电路中的电源。然后调节由电源产生的电流以增加或减小超导磁体中的电流密度以分别以受控方式升高或降低磁场强度。基于超导磁体的操作参数和电源产生的电流来确定和优化磁场强度变化的变化率。

7. 发明公开

EP3047292A1 COIL ASSEMBLY FOR MAGNETIC RESONANCE IMAGING 有权转让
标题翻译： SPULENANORDNUNGFÜRDIE MAGNETRESONANZBILDGEBUNG
公开(公告)号：EP3047292A1
公开(公告)日：2016-07-27
申请号：EP14845896.1
申请日：2014-09-17
申请人： Synaptive Medical (Barbados) Inc.
发明人： PIRON, Cameron , PANTHER, Alex , THINGVOLD, Sheryl , HARRIS, Chad , STAINSBY, Jeff
IPC分类号： G01R33/341
CPC分类号： G01R33/34053 , A61B5/0042 , A61B5/055 , A61M16/01 , A61M16/08 , G01R33/283 , G01R33/288 , G01R33/30 , G01R33/34046 , G01R33/385 , G01R33/3858
摘要： A magnetic resonance imaging system is provided. The system includes a solenoid magnet configured to generate a static magnetic field and an annular coil assembly housed within at least a portion of the solenoid magnet. The coil assembly includes a gradient coil, wherein the annular coil assembly has an aperture formed therein.
摘要翻译：提供磁共振成像系统。该系统包括配置成产生静磁场的螺线管磁体和容纳在螺线管磁体的至少一部分内的环形线圈组件。线圈组件包括梯度线圈，其中环形线圈组件具有形成在其中的孔。

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