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1. 发明公开

EP1849779A1 ESTERIFIED CATECHIN, PROCESS FOR PRODUCING THE SAME, FOOD AND DRINK OR COSMETIC CONTAINING THE SAME 审中-公开
标题翻译：酯化儿茶素，METHOD FOR ITS，食品和饮料或美容，这包括
公开(公告)号：EP1849779A1
公开(公告)日：2007-10-31
申请号：EP06712293.7
申请日：2006-01-25
申请人： SUNTORY LIMITED
发明人： FUKAMI, Harukazu , NAKAO, Masahiro , NAMIKAWA, Koshi , MAEDA, Mitsuru
IPC分类号： C07D311/62 , A01N43/16 , A23L3/3517
CPC分类号： C12P17/06 , A01N43/16 , A23L3/3472 , A23L3/3517 , A61K8/498 , A61Q17/005 , C07D311/62
摘要： The present invention provides substances having sufficiently antibacterial activity against heat-resistant spore-forming bacteria that they can be used to improve the shelf life of beverages and processed foods, as well as to control the growth of microorganisms in cosmetics.
The present invention provides a catechin ester in which at least one of the hydroxyl groups of a catechin is esterified with a medium-chain fatty acid. This medium-chain fatty acid ester of a catechin, which may be used either alone or as a composition, shows a strong growth suppressing effect on heat-resistant spore-forming bacteria and, if added to foods or beverages, can prevent them from rotting or deterioration and, if added to cosmetics, can prevent their rotting or deterioration.
摘要翻译：本发明提供了具有针对thatthey可用于改善饮料和加工食品的货架期，以及用于控制微生物在化妆品中的生长充分的耐热孢子形成细菌的抗菌活性的物质。本发明提供了其中A儿茶素的羟基中的至少一个被酯化与中链脂肪酸儿茶素酯。儿茶素，其可以单独地或作为组合物中使用的这种中链脂肪酸酯，表现出强的生长在抑制效果耐热孢子形成的细菌，并且如果添加到食品或饮料，可以防止它们腐烂或变质，如果添加到化妆品中，可以防止其腐败变质。

2. 发明公开

EP0757051A1 PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME 失效
标题翻译：印度尼西亚反犹太人解放阵线
公开(公告)号：EP0757051A1
公开(公告)日：1997-02-05
申请号：EP96902477.7
申请日：1996-02-19
申请人： SUNTORY LIMITED
发明人： ISHIGURO, Masaji , NAKATSUKA, Takashi , TANAKA, Rie , NAMIKAWA, Koshi , MATSUKI, Shinsuke
IPC分类号： C07D499/88 , A61K31/43
CPC分类号： C07D499/88 , Y02P20/55
摘要： A penem derivative represented by the following formula (I):
wherein R 1 represents a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted alkylthio group, a substituted or unsubstituted alkenylthio group, a substituted or unsubstituted aralkylthio group, a substituted or unsubstituted arylthio group, a substituted or unsubstituted heterocyclic group, a substituted or unsubstituted heterocyclic thio group, a substituted or unsubstituted acylthio group, a mercapto group or a hydrogen atom, and R 2 represents a hydrogen atom or a carboxyl-protecting group; or a pharmacologically acceptable salt thereof.
The compound (I) exhibits strong antibacterial activities, and especially, shows strong activities against MRSA. It is therefore useful not only as a general antibacterial agent but also as an antibacterial agent for MRSA against which no general antibacterial agents are recognized to be effective.
摘要翻译：由下式（I）表示的pen嗪衍生物：其中R 1表示取代或未取代的烷基，取代或未取代的烯基，取代或未取代的芳烷基，取代或未取代的芳基，取代或未取代的芳基取代或未取代的芳硫基，取代或未取代的芳硫基，取代或未取代的杂环基，取代或未取代的杂环硫基，取代或未取代的酰硫基，巯基或巯基氢原子，R 2表示氢原子或羧基保护基; 或其药理学上可接受的盐。化合物（I）表现出强烈的抗菌活性，特别是对MRSA具有强烈的活性。因此，不仅可以作为普通抗菌剂，而且作为MRSA的抗菌剂也是有用的，因为没有一般的抗菌剂被认为是有效的。

3. 发明公开

EP1738647A1 PROCESS FOR PRODUCING MALLOTUS PHILIPPENSIS COLORANT COMPOSITION AND THE COMPOSITION 审中-公开
标题翻译： VERFAHREN ZUR GEWINNUNG EINES FARBMITTELS AUS MALLOTUS PHILIPPENSIS SOWIE FARBMITTEL
公开(公告)号：EP1738647A1
公开(公告)日：2007-01-03
申请号：EP05720596.5
申请日：2005-03-11
申请人： SUNTORY LIMITED
发明人： MAEDA, Mitsuru , FUKAMI, Harukazu , NAMIKAWA, Koshi
IPC分类号： A01N43/16 , A01N65/00 , A23L1/275 , A23L3/349 , A61P33/10 , C09B61/00 , C09B67/54
CPC分类号： C09B61/00 , A01N43/16 , A01N65/18 , A23L3/44 , A23L5/43 , A61K8/498 , A61K8/97 , A61K36/47 , A61K2800/43 , A61Q1/02
摘要： An object of the present invention is to provide a Mallotus philippinensis extract containing readily water soluble rottlerin. A further object of the present invention is to improve convenience at production steps in a method for producing such an extract, by avoiding the staining of filters and/or pipes during extraction and filtration to reduce washing costs, or by facilitating the introduction of freeze drying and so on. When a dye extract is extracted with water and alcohol from a Mallotus philippinensis plant body, the addition of a base component drastically improves the water solubility of the Mallotus philippinensis extract. This improves extraction rates of rottlerin, facilitates washing in the production and the pulverization of the extract, and also improves the water solubility of the obtained extract.
摘要翻译：本发明的一个目的是提供一种含有容易溶解水溶性罗丹明胆的Mallotus philippinensis提取物。本发明的另一个目的是通过避免在提取和过滤期间过滤器和/或管道的污染以降低洗涤成本，或者通过促进冷冻干燥的引入来提高生产这种提取物的方法的生产步骤的便利性等等。当从Mallotus philippinensis植物体中用水和酒精提取染料提取物时，添加碱性成分可显着提高Mal蛇提取物的水溶性。这提高了旋转蛋白的提取率，促进了生产中的洗涤和提取物的粉碎，并且还提高了所得提取物的水溶性。

4. 发明公开

EP1500645A1 ASTAXANTHIN MEDIUM-CHAIN FATTY ACID ESTER, PROCESS FOR PRODUCING THE SAME AND COMPOSITION CONTAINING THE ESTER 有权
标题翻译：虾青素脂肪酸与中等链长，工艺酯用于生产和组分与酯含有
公开(公告)号：EP1500645A1
公开(公告)日：2005-01-26
申请号：EP03728006.2
申请日：2003-04-28
申请人： SUNTORY LIMITED
发明人： SUMIDA, Motoo , NAKAO, Masahiro , TOMIMORI, Namino , NAMIKAWA, Koshi , FUKAMI, Harukazu
IPC分类号： C07C403/24 , C12P23/00 , A61K7/025 , A23L1/30
CPC分类号： C07C403/24 , A23L33/10 , A23L33/115 , A61K8/37 , A61Q1/06 , C12P7/62 , C12P7/6436 , C12P7/6454 , C12P23/00
摘要： The present invention provides an astaxanthin medium-chain fatty acid ester, which is expected to be applied in the fields of food, cosmetics and pharmaceuticals, and has higher digestibility and tissue penetration than long chain fatty acid ester form astaxanthins.
When the synthesis of an astaxanthin medium-chain fatty acid ester is attempted using the catalytic action of lipase by conventional methods, ester cannot be formed. However, according to the present invention, a composition comprising an astaxanthin medium-chain fatty acid monoester and/or diester is produced by adding a certain amount of water into a reaction system and reacting an astaxanthin or a long chain fatty acid ester thereof with a medium-chain fatty acid, a triglyceride thereof or a suitable ester. Moreover, these monoesters and/or diesters are isolated, as necessary. The present invention further provides food or cosmetics comprising the composition of the present invention.
摘要翻译：本发明提供了虾青素中链脂肪酸酯，所有这些都预期在食品，化妆品和药品等领域得到应用，并具有较高的消化率和组织穿透比长链脂肪酸酯形式的虾青素。 <？>当虾青素中链脂肪酸酯的合成使用由常规方法脂肪酶的催化作用尝试，酯不能形成。然而，雅鼎在本发明中，包含虾青素中链脂肪酸的单酯和/或二酯的组合物是通过将水一定量到反应体系，并用反应到虾青素或一个长链脂肪酸及其酯生成中链脂肪酸，它们的甘油三酯或合适的酯。更完了，论文的单酯和/或二酯是分离的，因为是必要的。本发明还提供了食品或化妆品含有本发明的组合物。

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