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1. 发明专利

AT64392T 未知
公开(公告)号：AT64392T
公开(公告)日：1991-06-15
申请号：AT87306508
申请日：1987-07-23
申请人： SUMITOMO PHARMA , SUMITOMO CHEMICAL CO
发明人： ENOMOTO MASAO , MURAOKA MASAMI , ONO KEIICHI , KOJIMA ATSUYUKI , ATSUMI TOSHIO , KOMURO YOSHIHIRO , SANEMITSU YUZURU , MIZUTANI MASATO
IPC分类号： A61K31/425 , A61K31/44 , A61P1/04 , A61P7/02 , A61P9/00 , A61P11/00 , A61P29/00 , C07D417/04

2. 发明专利

DE3770724D1 未知
公开(公告)号：DE3770724D1
公开(公告)日：1991-07-18
申请号：DE3770724
申请日：1987-07-23
申请人： SUMITOMO CHEMICAL CO , SUMITOMO PHARMA
发明人： ENOMOTO MASAO , MURAOKA MASAMI , ONO KEIICHI , KOJIMA ATSUYUKI , ATSUMI TOSHIO , KOMURO YOSHIHIRO , SANEMITSU YUZURU , MIZUTANI MASATO
IPC分类号： A61K31/425 , A61K31/44 , A61P1/04 , A61P7/02 , A61P9/00 , A61P11/00 , A61P29/00 , C07D417/04

3. 发明授权

US3541112A 1-(alicyclic substituted carbonyl)-3-indolyl aliphatic acid derivatives 失效
标题翻译： 1-（ALICYCLIC取代的羰基）-3-吲哚基乙酸衍生物
公开(公告)号：US3541112A
公开(公告)日：1970-11-17
申请号：US3541112D
申请日：1967-07-07
申请人： SUMITOMO CHEMICAL CO
发明人： YAMAMOTO HISAO , NAKAMURA YASUSHI , ATSUMI TOSHIO , NAKAO MASARU , KOBAYASHI TSUYOSHI , SAITO CHIHARU , AWATA HIROSHI
IPC分类号： A61K31/405 , C07D209/26 , C07D27/56
CPC分类号： C07C251/72 , C07D209/26

4. 发明授权

US3564008A Process for preparing 1-acyl-2-phenyl-3-indolylaliphatic acid derivatives 失效
标题翻译：制备1-乙酰基-2-苯基-3-间苯二酚酸衍生物的方法
公开(公告)号：US3564008A
公开(公告)日：1971-02-16
申请号：US3564008D
申请日：1968-01-03
申请人： SUMITOMO CHEMICAL CO
发明人： YAMAMOTO HISAO , NAKAMURA YASUSHI , NAKAO MASARU , ATSUMI TOSHIO , KOBAYASHI TSUYOSHI
IPC分类号： C07D209/26 , C07D27/56
CPC分类号： C07D209/26
摘要： A 1-ACYL-2-PHENYL-3-INDOYLALIPHATIC ACID DERIVATIVE REPRESENTED BY THE FORMULA,

1-(R2-CO-),2-(R3-PHENYL),3-(R5-CO-CH(-R4)-),R1-INDOLE

WHEREIN R1 IS A HYDROGEN ATOM, A LOWER ALKOXY GROUP, ETC.; R2 IS A HYDROGEN- OR LOWER ALKYL-SUBSTITUTED PHENYL GROUP, ETC.; R3 IS A HYDROGEN ATOM OR A LOWER ALKYL GROUP, ETC; R4 IS A HYDROGEN ATOM OR A LOWER ALKYL; AND R5 IS A HYDROXY GROUP, ETC., IS OBTAINED BY REACTING A CORRESPONDING N1-ACYL PHENYLHYDRAZINE DERIVATIVE OR A MINERAL ACID SALT THEREOF WITH A CORRESPONDING PHENYL KETONE COMPOUND. THE TYPICAL EXAMPLES THEREOF ARE 1-(P-CHLOROBENZOYL)2-PHENYL 5-METHOXY - 3 - INDOLYACETICA CID AND 1-(PMETHYLBENZOYL)-2-PHENYL - 5 - METHOXY - 3 - INDOLYLACETIC ACID. THE COMPOUNDS THUS OBTAINED HAVE REMARKABLE ANTIINFLAMMATORY, ANALGESIC AND ANTIPYRETIC ACTIONS.

5. 发明授权

US3564009A Process for producing 1-acylindole derivatives 失效
标题翻译：生产1-乙酰衍生物的方法
公开(公告)号：US3564009A
公开(公告)日：1971-02-16
申请号：US3564009D
申请日：1966-12-28
申请人： SUMITOMO CHEMICAL CO
发明人： YAMAMOTO HISAO , NAKAO MASARU , ATSUMI TOSHIO
IPC分类号： C07D209/08 , C07D209/12 , C07D209/14 , C07D27/56
CPC分类号： C07D209/12 , C07D209/08 , C07D209/14
摘要： A PROCESS FOR THE PREPARATION OF CERTAIN N-ACYLINDOLES BY THE REACTION OF AN N''-ACYLHYDRAZINE WITH A KETONE COMPOUND.

6. 发明授权

US3873706A Novel benzomorphan and their salts as analgesics 失效
标题翻译：新的BENZOMORPHAN和他们的销售作为理论
公开(公告)号：US3873706A
公开(公告)日：1975-03-25
申请号：US47284074
申请日：1974-05-23
申请人： SUMITOMO CHEMICAL CO
发明人： ATSUMI TOSHIO , KOBAYASHI KENJI , TAKEBAYASHI YOSHIAKI , YAMAMOTO HISAO
IPC分类号： C07D221/26 , A61K27/00
CPC分类号： C07D221/26
摘要： Benzomorphan derivatives of the formula:

WHEREIN R is a hydrogen atom, a C1-C3 alkoxy group, an acyloxy group, a hydroxy group, a nitro group, a halogen atom, a cyano group, an amino group, a carboxyl group, a carbamoyl group or a sulfo group; R1 is a hydrogen atom, a C1-C3 alkyl group or a group of the formula, (CmH(2m p) 1)-(R9)p (wherein m is an integer of 1-6; p is an integer of 1-2, and R9 is a hydroxyl group or a C1-C3 alkoxy group); R2 is a hydrogen atom or a C1-C3 alkyl group; R3 and R4 are independently a hydrogen atom, a halogen atom, a C1-C3 alkyl group, a C1-C3 alkoxy group, a C1-C3 alkylthio group, a nitro group, a trifluoromethyl group, an amino group or a hydroxyl group; R5 is a hydrogen atom or a methyl group; R6 is a hydrogen atom or a C1-C3 alkyl group; R7 is a hydrogen atom, a C1-C3 alkyl group, a phenyl group or a C1-C3 alkoxyphenyl group; R8 is a hydrogen atom or a hydroxyl group, or R7 and R8 may form a C1-C3 alkylidene group or a carbonyl group together with a carbon atom to which these substituents are bonded; and n is an integer of 2-4, provided that, when n is an integer of 2, R1 and R2 are a methyl group, R is a hydrogen atom or a hydroxyl group and R4, R5, R6, R7 and R8 are hydrogen atoms, R3 must be a halogen atom, a C1-C3 alkyl group, a C1-C3 alkoxy group, a C1-C3 alkylthio group, a nitro group, a trifluoromethyl group, an amino group or a hydroxyl group, which are useful as non-addicting, analgesic and pain-relieving agents with calming effect.
摘要翻译：下式的苯并吗啉衍生物：

7. 发明授权

US3631051A Process for producing 2-substituted 6 7-benzomorphan derivatives 失效
标题翻译：用于生产2-取代的6,7-苯并吡喃衍生物的方法
公开(公告)号：US3631051A
公开(公告)日：1971-12-28
申请号：US3631051D
申请日：1969-05-28
申请人： SUMITOMO CHEMICAL CO
发明人： ATSUMI TOSHIO , KOBAYASHI KENJI , TAKEBAYASHI YOSHIAKI , YAMAMOTO HISAO
IPC分类号： C04B41/62 , C07D211/68 , C07D211/80 , C07D221/26 , C07D39/00
CPC分类号： C07D221/26 , C04B41/62 , C07D211/68 , C07D211/80
摘要： A PROCESS FOR PREPARING 2-SUBSTITUTED 6,7-BENZOMORPHAN DERIVATIVES, AND SALTS THEREOF, REPRESENTED BY THE GENERAL FORMULA,

3-(R4-C(-R5)=C(-R3)-CH2-),6-R1,8-R6,11-R2-1,2,3,4,5,6-

HEXAHYDRO-2,6-METHANO-3-BENZAZOCINE

WHEREIN R1 AND R2 ARE RESPECTIVELY C1-C3 ALKYL GROUPS; R3 R4 AND R5 RESPECTIVELY HYDROGEN ATOMS OR C1-C3 ALKYL GROUPS; R6 IS A HYDROGEN ATOM, A HYDROXYL GROUP, A C1-C3 ALKYL GROUP OR A C1-C3 ALKOXY GROUP, WHICH PROCESS COMPRISES CONTACTING WITH A MIXTURE OF PHOSPHORIC ACID AND PHOSPHORUS PENTIOXIDE, THE RATIO OF PHOSPHORUS PENTOXIDE TO PHOSPHORIC ACID BEING 0.2 TO 2.0 ON THE BASE OF WEIGHT, A 1-SUBSTITUTED 1,2,5,6-TETRAHYDROPYRIDINE DERIVATIVE, OR A SALT THEREOF, REPRESENTED BY THE GENERAL FORMULA,

1-(R4-C(-R5)=C(-R3)-CH2-),3-R2,4-R1,2-((4-R6-PHENYL)-CH2-)

1,2,5,6-TETRAHYDROPYRIMIDINE

WHEREIN R1, R2, R3, R4, R5, AND R6 ARE AS DEFINED ABOVE, THE CYCLISATION REACTION BEING CONDUCTED IN AN ANHYDROUS STATE. THE BENZOMORPHAN DERIVATIVES ARE USEFUL AS ANALGESICS.

8. 发明授权

US3535326A Certain tetrahydro carboline derivatives 失效
标题翻译：某些四氯化碳衍生物
公开(公告)号：US3535326A
公开(公告)日：1970-10-20
申请号：US3535326D
申请日：1967-03-06
申请人： SUMITOMO CHEMICAL CO
发明人： YAMAMOTO HISAO , NAKAMURA YASUSHI , NAKAO MASARU , ATSUMI TOSHIO , KOBAYASHI TSUYOSHI
IPC分类号： C07D209/94 , C07D401/06 , C07D471/04 , C07D31/44
CPC分类号： C07D401/06 , C07D209/94 , C07D471/04

9. 发明专利

DE3476800D1 1,2,4-TRIAZOLYLPROPANOLS, AND THEIR PRODUCTION AND USE 未知
公开(公告)号：DE3476800D1
公开(公告)日：1989-03-30
申请号：DE3476800
申请日：1984-09-25
申请人： SUMITOMO CHEMICAL CO
发明人： SAJI IKUTARO , OHUCHI RENZO , ICHISE KATSUAKI , TANIO TOMOHARU , OKUDA TAKAO , ATSUMI TOSHIO
IPC分类号： A01N43/653 , C07D249/08 , C07D521/00 , A61K31/41

10. 发明专利

CA1232909A 1,2,4-TRIAZOLYLPROPANOLS, AND THEIR PRODUCTION AND USE 未知
公开(公告)号：CA1232909A
公开(公告)日：1988-02-16
申请号：CA463382
申请日：1984-09-17
申请人： SUMITOMO CHEMICAL CO
发明人： SAJI IKUTARO , OHUCHI RENZO , ICHISE KATSUAKI , TANIO TOMOHARU , OKUDA TADAO , ATSUMI TOSHIO
IPC分类号： A01N43/653 , C07D249/08 , C07D521/00
摘要： 1,2,4-TRIAZOLYLPROPANOLS, AND THEIR PRODUCTION AND USE A 1,2,4-triazolylpropanol of the formula: (I) wherein R is a straight or branched C5 alkyl group, and an acid addition salt thereof, which is useful as an antifungal agent.

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