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1. 发明授权

EP0143994B1 Thermoplastic resin-silicone composite shaped article 无效
标题翻译：热塑性树脂 - 硅胶复合材料
公开(公告)号：EP0143994B1
公开(公告)日：1992-01-02
申请号：EP84113150.1
申请日：1984-10-31
申请人： SUMITOMO BAKELITE COMPANY LIMITED , FUJI SYSTEMS CORPORATION
发明人： Onohara, Masayuki , Kawai, Kenji , Shibata, Masaru , Igarashi, Akira , Kawaguchi, Nobuhisa
IPC分类号： C08J7/04 , C08J5/12 , B32B27/08 , A61L33/00
CPC分类号： B32B27/08 , A61L33/068 , B32B27/283 , B32B27/322 , B32B38/0008 , B32B2305/72 , C08J7/047 , C08J2483/00 , C08L83/04

2. 发明公开

EP0143994A2 Thermoplastic resin-silicone composite shaped article 无效
标题翻译： Geformter Verbundstoff aus thermoplastischen Harzen und Silikonen。
公开(公告)号：EP0143994A2
公开(公告)日：1985-06-12
申请号：EP84113150.1
申请日：1984-10-31
申请人： SUMITOMO BAKELITE COMPANY LIMITED , FUJI SYSTEMS CORPORATION
发明人： Onohara, Masayuki , Kawai, Kenji , Shibata, Masaru , Igarashi, Akira , Kawaguchi, Nobuhisa
IPC分类号： C08J7/04 , C08J5/12 , B32B27/08 , A61L33/00
CPC分类号： B32B27/08 , A61L33/068 , B32B27/283 , B32B27/322 , B32B38/0008 , B32B2305/72 , C08J7/047 , C08J2483/00 , C08L83/04
摘要： A thermoplastic resin-silicone composite shaped article comprising (a) a shaped article of a thermoplastic resin selected from the group consisting of soft vinyl chloride resins, olefin resins, urethane resins and styrene resins and (b) a cured layer of an addition polymerization type silicone composition adhering to the one or both surfaces of the shaped article of a thermoplastic resin. To the surface of the above shaped article of a thermoplastic resin to which the above cured layer of an addition polymerization type silicone composition does not adhere, there may adhere another cured layer of the above addition polymerization type silicone composition. To either or both of these cured layers, there may further adhere a layer of the above thermoplastic resin, other thermoplastic resin, a silicone rubber, a silicone resin, glass, ceramics or a metal.
摘要翻译：一种热塑性树脂硅酮复合成形制品，其包括（a）选自软氯乙烯树脂，烯烃树脂，聚氨酯树脂和苯乙烯树脂的热塑性树脂的成型制品和（b）加成聚合型固化层硅酮组合物粘附在热塑性树脂的成形制品的一个或两个表面上。在加成聚合型有机硅组合物的上述固化层不粘合的热塑性树脂的上述成形体的表面上，可以附着上述加成聚合型有机硅组合物的另一固化层。对于这些固化层中的任一种或两者，可以进一步粘附上述热塑性树脂，其它热塑性树脂，硅橡胶，硅树脂，玻璃，陶瓷或金属的层。

3. 发明公开

EP0143994A3 Thermoplastic resin-silicone composite shaped article 无效
标题翻译：热塑性树脂 - 硅胶复合材料
公开(公告)号：EP0143994A3
公开(公告)日：1986-08-27
申请号：EP84113150
申请日：1984-10-31
申请人： SUMITOMO BAKELITE COMPANY LIMITED , FUJI SYSTEMS CORPORATION
发明人： Onohara, Masayuki , Kawai, Kenji , Shibata, Masaru , Igarashi, Akira , Kawaguchi, Nobuhisa
IPC分类号： C08J07/04 , C08J05/12 , B32B27/08 , A61L33/00
CPC分类号： B32B27/08 , A61L33/068 , B32B27/283 , B32B27/322 , B32B38/0008 , B32B2305/72 , C08J7/047 , C08J2483/00 , C08L83/04
摘要： A thermoplastic resin-silicone composite shaped article comprising (a) a shaped article of a thermoplastic resin selected from the group consisting of soft vinyl chloride resins, olefin resins, urethane resins and styrene resins and (b) a cured layer of an addition polymerization type silicone composition adhering to the one or both surfaces of the shaped article of a thermoplastic resin. To the surface of the above shaped article of a thermoplastic resin to which the above cured layer of an addition polymerization type silicone composition does not adhere, there may adhere another cured layer of the above addition polymerization type silicone composition. To either or both of these cured layers, there may further adhere a layer of the above thermoplastic resin, other thermoplastic resin, a silicone rubber, a silicone resin, glass, ceramics or a metal.

4. 发明授权

EP0168755B1 Container and method for storing blood 失效
标题翻译：容器和储存血液的方法
公开(公告)号：EP0168755B1
公开(公告)日：1991-04-17
申请号：EP85108529.0
申请日：1985-07-09
申请人： SUMITOMO BAKELITE COMPANY LIMITED , Sato, Toru
发明人： Sato, Toru , Matsuda, Atsuya , Shibata, Masaru , Onohara, Masayuki
IPC分类号： A61J1/05
CPC分类号： B32B25/08 , A61J1/10 , B32B3/266 , B32B25/20 , B32B2307/31 , B32B2307/54 , B32B2307/724 , B32B2439/80 , Y10T428/1334 , Y10T428/1386 , Y10T428/31663

5. 发明公开

EP0168755A3 Container and method for storing blood 失效
标题翻译：容器和储存血液的方法
公开(公告)号：EP0168755A3
公开(公告)日：1987-06-16
申请号：EP85108529
申请日：1985-07-09
申请人： SUMITOMO BAKELITE COMPANY LIMITED , Sato, Toru
发明人： Sato, Toru , Matsuda, Atsuya , Shibata, Masaru , Onohara, Masayuki
IPC分类号： A61J01/00
CPC分类号： B32B25/08 , A61J1/10 , B32B3/266 , B32B25/20 , B32B2307/31 , B32B2307/54 , B32B2307/724 , B32B2439/80 , Y10T428/1334 , Y10T428/1386 , Y10T428/31663
摘要： This invention relates to container and method for storing blood and blood concentrates preparations such as whole blood, packed red cells, platelet concentrates and the like (hereinafter referred to as blood). This invention aims at extending the possible storage period of blood by using a material having a high permeability to carbon dioxide gas as a synthetic resin film constituting the container for storing blood. According to this invention, by using a film composed of, besides a single layer of synthetic resin, a laminate film produced by integrally combining two or more kinds of thermoplastic synthetic resin layers or integrally combining a thermoplastic synthetic resin film and an addition polymerization type silicone rubber layer, there can be obtained a practically usable container for storing blood the constitutive layers or film of which mutually make up for the defects of a single layer of each resin, and which is hence excellent in permeability to carbon dioxide gas and blood-storing ability, and moreover is well balanced among physical properties other than them such as heat resistance, mechanical strength and the like. Concretely, said container and method are a container for storing blood made of a synthetic resin film which has a permeability to carbon dioxide gas of 5,000 ml/m 2 · 24' hr atm or higher at 25°C for storage of whole blood or a packed red cells, has an excellent fitness for blood of its surface to be contacted with blood, has a rigidity of 5 kg/cm width or less in terms of tensile strength, permits easy handling of the storage container, and has a strength of seal by heat seal or adhesion working of 1.5 kg/cm width or more, so that the film is excellent in bag-forming property; and a method for storing blood using said container which comprises maintaining the partial pressure of carbon dioxide gas after storage of blood for more than 1 week at 85 mmHg or less, and storing blood at not higher than 6°C and not lower than 0°C so that even after storage for 2 weeks, the concentration of 2,3-DPG is 2.0 µmol/ml of erythrocytes or more and the pH is 6.7 or more. Here, the values, of the partial pressure of carbon dioxide gas and the pH are those measured after storing blood containing CPD at a low temperature, followed by raising the temperature to 37°C while keeping airtightness for gas pressure measurements. For platelets, a storage container composed of a laminate film prepared by integrally combining a thermoplastic synthetic resin film and an addition polymer type silicone rubber layer which container has a permeability to carbon dioxide gas of 2,000 to 9,000 ml/ m 2. 24 hr atm, is effective.

6. 发明公开

EP0168755A2 Container and method for storing blood 失效
标题翻译： Behälterund Verfahren zur Aufbewahrung von Blut。
公开(公告)号：EP0168755A2
公开(公告)日：1986-01-22
申请号：EP85108529.0
申请日：1985-07-09
申请人： SUMITOMO BAKELITE COMPANY LIMITED , Sato, Toru
发明人： Sato, Toru , Matsuda, Atsuya , Shibata, Masaru , Onohara, Masayuki
IPC分类号： A61J1/05
CPC分类号： B32B25/08 , A61J1/10 , B32B3/266 , B32B25/20 , B32B2307/31 , B32B2307/54 , B32B2307/724 , B32B2439/80 , Y10T428/1334 , Y10T428/1386 , Y10T428/31663
摘要： This invention relates to container and method for storing blood and blood concentrates preparations such as whole blood, packed red cells, platelet concentrates and the like (hereinafter referred to as blood). This invention aims at extending the possible storage period of blood by using a material having a high permeability to carbon dioxide gas as a synthetic resin film constituting the container for storing blood. According to this invention, by using a film composed of, besides a single layer of synthetic resin, a laminate film produced by integrally combining two or more kinds of thermoplastic synthetic resin layers or integrally combining a thermoplastic synthetic resin film and an addition polymerization type silicone rubber layer, there can be obtained a practically usable container for storing blood the constitutive layers or film of which mutually make up for the defects of a single layer of each resin, and which is hence excellent in permeability to carbon dioxide gas and blood-storing ability, and moreover is well balanced among physical properties other than them such as heat resistance, mechanical strength and the like. Concretely, said container and method are a container for storing blood made of a synthetic resin film which has a permeability to carbon dioxide gas of 5,000 ml/m 2 · 24' hr atm or higher at 25°C for storage of whole blood or a packed red cells, has an excellent fitness for blood of its surface to be contacted with blood, has a rigidity of 5 kg/cm width or less in terms of tensile strength, permits easy handling of the storage container, and has a strength of seal by heat seal or adhesion working of 1.5 kg/cm width or more, so that the film is excellent in bag-forming property; and a method for storing blood using said container which comprises maintaining the partial pressure of carbon dioxide gas after storage of blood for more than 1 week at 85 mmHg or less, and storing blood at not higher than 6°C and not lower than 0°C so that even after storage for 2 weeks, the concentration of 2,3-DPG is 2.0 µmol/ml of erythrocytes or more and the pH is 6.7 or more. Here, the values, of the partial pressure of carbon dioxide gas and the pH are those measured after storing blood containing CPD at a low temperature, followed by raising the temperature to 37°C while keeping airtightness for gas pressure measurements. For platelets, a storage container composed of a laminate film prepared by integrally combining a thermoplastic synthetic resin film and an addition polymer type silicone rubber layer which container has a permeability to carbon dioxide gas of 2,000 to 9,000 ml/ m 2. 24 hr atm, is effective.
摘要翻译：本发明涉及用于储存血液和血液浓缩物制剂如全血，包装红细胞，血小板浓缩物等（以下称为血液）的容器和方法。本发明旨在通过使用构成用于储存血液的容器的合成树脂膜，通过使用对二氧化碳气体具有高渗透性的材料来延长血液的可能储存期。根据本发明，通过使用由单层合成树脂构成的膜，通过一体地组合两种以上的热塑性合成树脂层或者一体地组合热塑性合成树脂膜和加成聚合型硅氧烷橡胶层，可以获得用于存储血液的实际可用的容器，其中构成层或膜相互弥补每个树脂的单层的缺陷，因此具有优异的二氧化碳气体和血液储存的渗透性能力，而且除了耐热性，机械强度等之外的物理性能之间是均衡的。具体地说，所述容器和方法是一种用于储存由二氧化碳气体的渗透性为5000ml / m 2的合成树脂薄膜制成的容器，25℃时为24小时以上，以保存全血或填充的红细胞，其表面与血液接触的血液具有优异的适应性，拉伸强度方面的刚度为5kg / cm以下，容易处理储存容器，具有强度的密封或密封加工1.5kg / cm以上的宽度或更大，使膜成型性优异; 以及使用所述容器保存血液的方法，其包括在血液储存1周以上时保持二氧化碳气体的分压为85mmHg以下，并且将血液保存在不高于6℃且不低于0℃ 因此，即使在保存2周后，2,3-DPG的浓度为2.0μmol/ ml以上的红细胞以上，pH为6.7以上。这里，二氧化碳气体的分压值和pH值是在储存含有CPD的血液在低温下测量的值，然后将温度升高至37℃，同时保持气体压力测量的气密性。对于血小板，由通过将热塑性合成树脂膜和加成聚合物型硅橡胶层整体结合而制备的层压膜构成的储存容器，该容器对二氧化碳气体的渗透性为2,000〜9,000ml / m 2 .24hr.atm ，是有效的。

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