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1. 发明申请

US20160281135A1 Biological Detection System and Method of Use 审中-公开
标题翻译：生物检测系统及其使用方法
公开(公告)号：US20160281135A1
公开(公告)日：2016-09-29
申请号：US15055311
申请日：2016-02-26
申请人： STOKES BIO LIMITED
发明人： Mauro Aguanno , Brian T. Chawke , Kieran Curran , Tara Dalton , Mark Davies , Xiaona Hou , David Kinahan , Mark Korenke , David McGuire , Michael Sayers , Noel Sirr , Ryan J. Talbot , Brian Barrett , Damian Curtin , Damien King , Conor McCarthy
IPC分类号： C12Q1/68 , G01N21/64 , G01N35/00 , B01L7/00 , B01L3/00
CPC分类号： C12Q1/686 , B01F13/0005 , B01F13/0071 , B01F15/00214 , B01L3/502715 , B01L3/502784 , B01L7/52 , B01L7/525 , B01L2200/143 , B01L2300/06 , B01L2300/0654 , B01L2300/0867 , G01N21/6428 , G01N35/00623 , G01N2021/6439 , G01N2021/6441 , G01N2035/00465 , G01N2201/062
摘要： Provided herein is a biological detection system and method of use wherein the biological detection system comprises at least one mixer or liquid bridge for combining at least two liquid droplets and an error correction system for detecting whether or not proper mixing or combining of the two component droplets have occurred.
摘要翻译：本文提供了一种生物检测系统和使用方法，其中生物检测系统包括用于组合至少两个液滴的至少一个混合器或液体桥，以及用于检测是否适当混合或组合两个组分液滴的误差校正系统已经发生

2. 发明授权

US10513729B2 Biological detection system and method of use 有权
公开(公告)号：US10513729B2
公开(公告)日：2019-12-24
申请号：US15055311
申请日：2016-02-26
申请人： STOKES BIO LIMITED
发明人： Mauro Aguanno , Brian T. Chawke , Kieran Curran , Tara Dalton , Mark Davies , Xiaona Hou , David Kinahan , Mark Korenke , David McGuire , Michael Sayers , Noel Sirr , Ryan J. Talbot , Brian Barrett , Damian Curtin , Damien King , Conor McCarthy
IPC分类号： B01L3/00 , C12Q1/686 , B01F13/00 , B01F15/00 , G01N21/64 , B01L7/00 , G01N35/00
摘要： Provided herein is a biological detection system and method of use wherein the biological detection system comprises at least one mixer or liquid bridge for combining at least two liquid droplets and an error correction system for detecting whether or not proper mixing or combining of the two component droplets have occurred.

3. 发明授权

US09789484B2 System and method for charging fluids 有权
公开(公告)号：US09789484B2
公开(公告)日：2017-10-17
申请号：US15048812
申请日：2016-02-19
申请人： STOKES BIO LIMITED
发明人： Brian Chawke , Kieran Curran , David McGuire , Michael Sayers , Noel Sirr
IPC分类号： B05B5/053 , B01L3/00 , B01F13/00 , G01N1/38 , B01J19/08 , B05B5/035 , C12Q1/68 , G01N1/40
CPC分类号： B01L3/50273 , B01F13/0071 , B01F13/0076 , B01J19/087 , B01L3/502715 , B01L3/502784 , B01L3/52 , B01L3/56 , B01L2200/0673 , B01L2300/0867 , B01L2400/0406 , B01L2400/0415 , B05B5/035 , C12Q1/686 , G01N1/38 , G01N2001/4038
摘要： Devices, systems, and methods for charging fluids are disclosed. The charging of fluids improves the mixing of fluids in microfluidic systems. The charging is performed by producing an ion field between an ionizing electrode and an opposed ground electrode. A fluid-containing vessel is positioned between the opposed electrodes and the ion field charges the fluid in the vessel.

4. 发明授权

US09387472B2 Sampling device 有权
标题翻译：取样装置
公开(公告)号：US09387472B2
公开(公告)日：2016-07-12
申请号：US14295223
申请日：2014-06-03
申请人： STOKES BIO LIMITED
发明人： Mark Davies , Tara Dalton , Michael Sayers , Brian T. Chawke
IPC分类号： B01L3/02 , B01L7/00
CPC分类号： B01L3/021 , B01L3/0293 , B01L7/52 , B01L2200/0642 , B01L2200/0673 , Y10T436/25 , Y10T436/25625
摘要： The present invention generally relates to devices, systems, and methods for acquiring and/or dispensing a sample without introducing a gas into a microfluidic system, such as a liquid bridge system. An exemplary embodiment provides a sampling device including an outer sheath; a plurality of tubes within the sheath, in which at least one of the tubes acquires a sample, and at least one of the tubes expels a fluid that is immiscible with the sample, in which the at least one tube that acquires the sample is extendable beyond a distal end of the sheath and retractable to within the sheath; and a valve connected to a distal portion of the sheath, in which the valve opens when the tube extends beyond the distal end and closes when the tube retracts to within the sheath.
摘要翻译：本发明一般涉及用于获取和/或分配样品而不将气体引入诸如液体桥系统的微流体系统中的装置，系统和方法。示例性实施例提供了一种包括外护套的取样装置; 鞘内的多个管，其中至少一个管获取样品，并且至少一个管排出与样品不混溶的流体，其中获取样品的至少一个管可扩展超出护套的远端并伸缩到护套内; 以及连接到所述护套的远端部分的阀，当所述管延伸超过所述远端时所述阀打开，并且当所述管缩回到所述护套内时所述阀闭合。

5. 发明申请

US20160271606A1 SYSTEM AND METHOD FOR CHARGING FLUIDS 有权
标题翻译：充气流体的系统和方法
公开(公告)号：US20160271606A1
公开(公告)日：2016-09-22
申请号：US15048812
申请日：2016-02-19
申请人： STOKES BIO LIMITED
发明人： Brian Chawke , Kieran Curran , David McGuire , Michael Sayers , Noel Sirr
IPC分类号： B01L3/00 , B05B5/035 , C12Q1/68 , B01J19/08
CPC分类号： B01L3/50273 , B01F13/0071 , B01F13/0076 , B01J19/087 , B01L3/502715 , B01L3/502784 , B01L3/52 , B01L3/56 , B01L2200/0673 , B01L2300/0867 , B01L2400/0406 , B01L2400/0415 , B05B5/035 , C12Q1/686 , G01N1/38 , G01N2001/4038
摘要： Devices, systems, and methods for charging fluids are disclosed. The charging of fluids improves the mixing of fluids in microfluidic systems. The charging is performed by producing an ion field between an ionizing electrode and an opposed ground electrode. A fluid-containing vessel is positioned between the opposed electrodes and the ion field charges the fluid in the vessel.
摘要翻译：公开了用于充液的装置，系统和方法。流体充液改善了微流体系统中流体的混合。通过在电离电极和相对的接地电极之间产生离子场来进行充电。含流体的容器位于相对的电极之间，并且离子场对容器中的流体进行充电。

6. 发明申请

US20140349387A1 Sampling Device 审中-公开
标题翻译：取样装置
公开(公告)号：US20140349387A1
公开(公告)日：2014-11-27
申请号：US14295223
申请日：2014-06-03
申请人： STOKES BIO LIMITED
发明人： Mark Davies , Tara Dalton , Michael Sayers , Brian T. Chawke
IPC分类号： B01L3/02
CPC分类号： B01L3/021 , B01L3/0293 , B01L7/52 , B01L2200/0642 , B01L2200/0673 , Y10T436/25 , Y10T436/25625
摘要： The present invention generally relates to devices, systems, and methods for acquiring and/or dispensing a sample without introducing a gas into a microfluidic system, such as a liquid bridge system. An exemplary embodiment provides a sampling device including an outer sheath; a plurality of tubes within the sheath, in which at least one of the tubes acquires a sample, and at least one of the tubes expels a fluid that is immiscible with the sample, in which the at least one tube that acquires the sample is extendable beyond a distal end of the sheath and retractable to within the sheath; and a valve connected to a distal portion of the sheath, in which the valve opens when the tube extends beyond the distal end and closes when the tube retracts to within the sheath.
摘要翻译：本发明一般涉及用于获取和/或分配样品而不将气体引入诸如液体桥系统的微流体系统中的装置，系统和方法。示例性实施例提供了一种包括外护套的取样装置; 鞘内的多个管，其中至少一个管获取样品，并且至少一个管排出与样品不混溶的流体，其中获取样品的至少一个管可扩展超出护套的远端并伸缩到护套内; 以及连接到所述护套的远端部分的阀，当所述管延伸超过所述远端时所述阀打开，并且当所述管缩回到所述护套内时所述阀闭合。

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