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    • 6. 发明申请
    • IMPROVED ANTIPERSPIRANT FORMULATIONS
    • 改进的抗尖端配方
    • WO9213516A3
    • 1992-11-26
    • PCT/US9105225
    • 1991-07-24
    • STEPAN CO
    • SHAPIRO IRENESAJIC BRANKO
    • A61K8/00A61K20060101A61K8/25A61K8/26A61K8/27A61K8/28A61K8/41A61K8/42A61K8/44A61K8/49A61K8/89A61K8/891A61K9/10A61K31/19A61Q15/00C07F20060101A61K7/32
    • A61Q15/00A61K8/445Y10S424/05Y10S514/938
    • Anhydrous and water-in-oil antiperspirant formulations are disclosed comprising effective suspending amounts of a compound of formula (A), wherein R1 and R2 are independently selected from the group consisting essentially of H or C1 - C40 linear or branched, substituted or unsubstituted alkyl, cycloalkyl, alkylene, alkaryl, aryl or R3-O-R4 groups, with R3 and R4 being independently selected from the group consisting essentially of C1 - C22 linear or branched, substituted or unsubstituted alkyl, cycloalkyl, alkylene, alkaryl and aryl groups; y is an integer of a value satisfying the valency of M; and M is a cation, preferably selected from the groups comprising H?+, Na+, K+, Ba++, Ca++, Mg++, Al+++, Ti+++, Zn++, NH¿4+, R5R6R7N+H wherein R¿5?, R6, and R7 are the same or different and are selected from the groups comprised of H, C1 - C20 linear or branched, substituted or unsubstituted alkyl, alkylene, aryl straight or branched chain alkyl or alkylene C1 - C40 groups or R8-O-R9 groups with R8 and R9 being independently selected from the groups comprised of C1 - C22 linear or branched, substituted or unsubstituted alkyl, cycloalkyl, alkylene, alkaryl and aryl groups, and mixtures thereof. Methods are also disclosed for preparing anhydrous and water-in-oil antiperspirant formulations.
    • 公开了包含有效悬浮量的式(A)化合物的无水和油包水止汗剂制剂,其中R 1和R 2独立地选自H或C 1 -C 40直链或支链,取代或未取代的烷基 烷基,烷芳基,芳基或R 3 -O-R 4基团,其中R 3和R 4独立地选自基本上由C 1 -C 22直链或支链,取代或未取代的烷基,环烷基,亚烷基,烷芳基和芳基组成的组; y是满足M的化合价的值的整数; 并且M是阳离子,优选选自H +,Na +,K +,Ba ++,Ca ++,Mg ++,Al +++,Ti +++,Zn ++,NH 4 +,4+,R 5 R 6 R 7 N + H,其中R 5,R 6和R 7 是相同或不同的并且选自H,C1-C20直链或支链,取代或未取代的烷基,亚烷基,芳基直链或支链烷基或亚烷基C1-C40基团或R8-O-R9基团与R8 和R9独立地选自由C1-C22直链或支链,取代或未取代的烷基,环烷基,亚烷基,烷芳基和芳基以及它们的混合物组成的组。 还公开了制备无水和油包水止汗剂制剂的方法。