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1. 发明申请

WO2012106354A1 ADJUSTABLE PROSTHETIC ANATOMICAL DEVICE HOLDER AND HANDLE FOR THE IMPLANTATION OF AN ANNULOPLASTY RING 审中-公开
标题翻译：可调节的前置解剖设备支架和手柄用于植入ANNULOPLASTY环
公开(公告)号：WO2012106354A1
公开(公告)日：2012-08-09
申请号：PCT/US2012/023359
申请日：2012-01-31
申请人： ST. JUDE MEDICAL, INC. , KOVACH, Melinda K. , CLEGG, Susan E. , MORRIS, Benjamin E. , FURNISH, Gregory R. , BIELEFELD, Eric E. , FURNISH, Simon M.
发明人： KOVACH, Melinda K. , CLEGG, Susan E. , MORRIS, Benjamin E. , FURNISH, Gregory R. , BIELEFELD, Eric E. , FURNISH, Simon M.
IPC分类号： A61F2/24
CPC分类号： A61F2/2466 , A61B5/1076 , A61F2/2445 , A61F2/2448 , A61F2/2496 , A61F2250/001 , A61F2250/006 , A61F2250/0065 , A61F2250/0089 , A61F2250/0097 , B25B15/02 , B25B23/142 , B25G1/046 , B25G3/18
摘要： An adjustable prosthetic anatomical holder system is disclosed. The system is adaptable for use in cardiac surgery and may include an adjustable annuloplasty ring, a ring holder, and a positioning handle. The adjustable annuloplasty ring holder facilitates placement and adjustment of the annuloplasty ring during a cardiac surgical procedure. An optional positioning handle holds the adjustable annuloplasty ring during placement and suturing of the ring. The ring holder is constructed from two members that are slidably fit together in telescopic arrangement to accommodate adjustment of the ring size.
摘要翻译：公开了一种可调节的假体解剖支架系统。该系统适用于心脏手术，并且可以包括可调环形成形术环，环保持器和定位手柄。可调节瓣环成形术环座在心脏外科手术过程中有利于瓣环成形术环的放置和调整。可选的定位手柄在环的放置和缝合期间保持可调节瓣环成形术环。环形支架由两个构件构成，这两个构件可伸缩地可滑动地配合在一起以适应环尺寸的调节。

2. 发明申请

WO2012177441A1 APPARATUS AND METHOD FOR HEART VALVE REPAIR 审中-公开
标题翻译：用于心脏瓣膜修复的装置和方法
公开(公告)号：WO2012177441A1
公开(公告)日：2012-12-27
申请号：PCT/US2012/042063
申请日：2012-06-12
申请人： ST. JUDE MEDICAL, INC. , GRIFFIN, Mark , MORRIS, Benjamin E. , BIELEFELD, Eric E. , FURNISH, Gregory R. , JOHNSON, Wayne A.
发明人： GRIFFIN, Mark , MORRIS, Benjamin E. , BIELEFELD, Eric E. , FURNISH, Gregory R. , JOHNSON, Wayne A.
IPC分类号： A61B17/064 , A61B17/29 , A61B17/068
CPC分类号： A61F2/2487 , A61B17/064 , A61B17/068 , A61B17/29 , A61B2017/00243 , A61B2017/00429 , A61B2017/0647 , A61B2017/2926
摘要： A device 10 for repairing mitral valve leaflets 2, 3 includes a jaw mechanism 15 that may be positioned adjacent a mitral valve leaflet 2, 3. The jaw mechanism 15 may move between an open position and a closed position by pivoting a first jaw relative 16 to a second jaw 18. The first jaw 16 may include a rivet 28 that may move from a stored position to an application position projecting away from the first jaw 16 when the jaw mechanism 15 is moved from the closed to the open position. Closing the jaws 16, 18 about a valve leaflet 2, 3 causes the rivet 28 to pierce the leaflet. The jaw mechanism 15 may then be rotated to wind the leaflet 2, 3 thereabout and again pierce the leaflet. The rivet 28 may then be released from the jaw mechanism 25 and the device 10 removed from the patient.
摘要翻译：用于修复二尖瓣小叶2,3的装置10包括钳口机构15，其可以邻近二尖瓣小叶2,3定位。钳口机构15可以通过使第一钳口相对于16枢转而在打开位置和关闭位置之间移动第二钳口16可以包括铆钉28，当夹爪机构15从关闭位置移动到打开位置时，铆钉28可以从存储位置移动到远离第一钳口16伸出的施加位置。关闭阀瓣16,18关于阀传单2,3使得铆钉28刺穿传单。然后可以将钳口机构15旋转以在其周围缠绕小叶2,3，并再次刺穿小叶。铆钉28然后可以从钳口机构25释放，并且装置10从患者身上移开。

3. 发明申请

WO2012106344A1 ADJUSTMENT ASSEMBLY FOR AN ADJUSTABLE PROSTHETIC VALVE DEVICE 审中-公开
标题翻译：调整装置用于可调节的前置阀装置
公开(公告)号：WO2012106344A1
公开(公告)日：2012-08-09
申请号：PCT/US2012/023333
申请日：2012-01-31
申请人： ST. JUDE MEDICAL, INC. , FURNISH, Gregory R. , WELLS, Brian K. , BETHARDS, Christopher , WEIR, Bruce R. , KOVACH, Melinda K.
发明人： FURNISH, Gregory R. , WELLS, Brian K. , BETHARDS, Christopher , WEIR, Bruce R. , KOVACH, Melinda K.
IPC分类号： A61F2/24
CPC分类号： A61F2/2466 , A61F2/0036 , A61F2/2445 , A61F2/2448 , A61F2250/0007 , A61F2250/001
摘要： An adjustment assembly for an adjustable prosthetic valve device includes a gearbox housing formed from two gearbox shells coupled to one another and held together by two gearbox sleeves each having an internal cavity adapted to accommodate respective lateral portions of the gearbox shells when the gearbox shells are coupled to one another. A gear assembly, including a center gear and two driven gears, is supported within the gearbox housing. Gear teeth of each of the driven gears engage gear teeth of the center gear such that rotation of the center gear causes rotation of the driven gears. At least one of the driven gears is adapted to engage a transmission mechanism that transmits the rotation thereof to another part of the adjustable prosthetic valve device to accomplish an adjustment to the size and/or shape of the adjustable prosthetic valve device.
摘要翻译：用于可调节人造瓣膜装置的调节组件包括由两个齿轮箱壳体形成的齿轮箱壳体，两个齿轮箱壳体彼此联接并由两个齿轮箱套筒保持在一起，每个齿轮箱套筒具有适于在齿轮箱壳体联接时适于容纳齿轮箱壳体的相应侧部的内部空腔彼此。包括中心齿轮和两个从动齿轮的齿轮组件被支撑在齿轮箱壳体内。每个从动齿轮的齿轮啮合中心齿轮的齿轮齿，使得中心齿轮的旋转引起从动齿轮的旋转。从动齿轮中的至少一个适于接合将其旋转传递到可调节的人造瓣膜装置的另一部分的传动机构，以完成对可调节的人造瓣膜装置的尺寸和/或形状的调整。

4. 发明申请

WO2012106328A1 ANTI-ROTATION LOCKING FEATURE 审中-公开
标题翻译：防旋转锁定功能
公开(公告)号：WO2012106328A1
公开(公告)日：2012-08-09
申请号：PCT/US2012/023309
申请日：2012-01-31
申请人： ST. JUDE MEDICAL, INC. , BIELEFELD, Eric E. , FURNISH, Gregory R. , BETHARDS, Christopher
发明人： BIELEFELD, Eric E. , FURNISH, Gregory R. , BETHARDS, Christopher
IPC分类号： A61F2/24 , B25B23/142 , B25B15/02 , B25G1/04 , B25B15/00
CPC分类号： A61F2/2466 , A61B5/1076 , A61F2/2445 , A61F2/2496 , A61F2250/001 , A61F2250/006 , A61F2250/0065 , A61F2250/0089 , A61F2250/0097 , B25B15/02 , B25B23/0064 , B25G1/046 , B25G3/18
摘要： An adjustment tool enables manipulation of a prosthetic anatomical device such as an annuloplasty ring. The tool includes a compression member which is operative for retarding rotation of the adjustment shaft to preclude inadvertent rotation thereof during use of the tool by the surgeon. A locking device is associated with the adjustment tool to enable the releasable attachment of the tool to the anatomical device during its adjustment by manipulation of the tool. The locking device is oriented into operative and inoperative positions by the engagement and disengagement of locking elements. A scale may be provided on the adjustment tool to assist a surgeon in determining the size or amount of adjustment to the size of the anatomical device during its adjustment.
摘要翻译：调节工具能够操作假体解剖装置，例如瓣环成形术环。该工具包括压缩构件，该压缩构件用于在外科医生使用该工具期间阻止调节轴的旋转以防止其意外旋转。锁定装置与调节工具相关联，以便在通过操纵工具进行调节期间使得工具能够可释放地附接到解剖装置。通过锁定元件的接合和分离，锁定装置被定位成操作和不工作的位置。可以在调节工具上提供刻度，以帮助外科医生确定在其调节期间对解剖装置的尺寸的调整的尺寸或量。

5. 发明申请

WO2011022246A1 MULTIFUNCTIONAL CORE FOR TWO-PIECE HEMOSTASIS CLIP 审中-公开
标题翻译：多功能核心用于双层HEMOSTASIS夹
公开(公告)号：WO2011022246A1
公开(公告)日：2011-02-24
申请号：PCT/US2010/044971
申请日：2010-08-10
申请人： BOSTON SCIENTIFIC SCIMED, INC. , COHEN, Adam L. , MORRIS, Benjamin E. , MISER, John , FURNISH, Gregory R. , JORDAN, Gary A.
发明人： COHEN, Adam L. , MORRIS, Benjamin E. , MISER, John , FURNISH, Gregory R. , JORDAN, Gary A.
IPC分类号： A61B17/122 , A61B17/128
CPC分类号： A61B17/1227 , A61B17/122 , A61B17/1285 , A61B2017/00473 , A61B2017/12004 , A61B2090/034 , A61B2090/037 , A61B2090/038
摘要： A device (100) includes a clip (104) including first and second arms (106) distal ends (112) of which are biased apart and a core member (102) including first and second portions connected to one another via a frangible link. The first portion includes a first protrusion (134) for engaging a cut-out in the first arm (106). The frangible link is fractured when subjected to a load of at least a predetermined level deploying the clip (104). The device (100) also includes a capsule (108) slidably housing the core member (102) and a proximal portion of the clip (104).
摘要翻译：装置（100）包括夹子（104），该夹子包括第一和第二臂（106），其远端（112）被偏压分开，并且芯构件（102）包括经由易碎连杆彼此连接的第一和第二部分。第一部分包括用于接合第一臂（106）中的切口的第一突起（134）。当受到部署夹子（104）的至少预定水平的载荷时，易碎链节断裂。装置（100）还包括可滑动地容纳芯构件（102）和夹子（104）的近侧部分的胶囊（108）。

6. 发明申请

WO2014022457A1 APPARATUS AND METHOD FOR HEART VALVE REPAIR 审中-公开
标题翻译：用于心脏瓣膜修复的装置和方法
公开(公告)号：WO2014022457A1
公开(公告)日：2014-02-06
申请号：PCT/US2013/052822
申请日：2013-07-31
申请人： ST. JUDE MEDICAL, INC.
发明人： MORRIS, Benjamin E. , MISER, John , FURNISH, Gregory R. , JOHNSON, Wayne A. , GRIFFIN, Mark
IPC分类号： A61B17/00 , A61B17/064
CPC分类号： A61B17/22031 , A61B17/00234 , A61B17/0218 , A61B17/0467 , A61B17/0644 , A61B17/083 , A61B17/12013 , A61B2017/00243 , A61B2017/00349 , A61B2017/00353 , A61B2017/00783 , A61B2017/00867 , A61B2017/0645 , A61B2017/0649 , A61F2/2454 , A61F2/2466
摘要： A device for transcatheter gathering of tissue of a heart valve leaflet may include an elongated tube (12) extending in a longitudinal direction and a capture tool (24) moveable in the elongated tube between a retracted position and an extended position. The elongated tube may have at least one slot (52, 252) extending generally in the longitudinal direction from a distal end of the elongated tube. The at least one slot may have an open end at the distal end of the elongated tube and a closed end remote therefrom. The capture tool may be operable to gather tissue of the heart valve leaflet into the at least one slot. The gathered tissue may have a pleated configuration.
摘要翻译：用于心脏瓣膜小叶的组织的经导管收集的装置可以包括沿纵向方向延伸的细长管（12）和捕获工具（24），其可在缩回位置和延伸位置之间在细长管中移动。细长管可以具有从细长管的远端大致沿纵向方向延伸的至少一个槽（52,252）。至少一个狭槽可以在细长管的远端处具有开口端，并且远离其的封闭端部。捕获工具可操作以将心脏瓣膜小叶的组织收集到至少一个狭槽中。聚集的组织可能具有打褶结构。

7. 发明申请

WO2013166356A2 DEVICES AND METHODS FOR TRANSCATHETER HEART VALVE DELIVERY 审中-公开
标题翻译：用于输送心脏瓣膜输送的装置和方法
公开(公告)号：WO2013166356A2
公开(公告)日：2013-11-07
申请号：PCT/US2013/039407
申请日：2013-05-03
申请人： ST. JUDE MEDICAL, INC. , ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
发明人： MORRIS, Benjamin E. , FURNISH, Gregory R. , BIELEFELD, Eric E. , THOMAS, Ralph J. , LE, Khoi A. , GLAZIER, Valerie J. , KNIPPEL, Bradley C.
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/962 , A61F2002/9517
摘要： A delivery device for a collapsible prosthetic heart valve includes an operating handle and a catheter assembly. The operating handle may include a housing defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, a deployment actuator coupled to the housing and rotatable relative to the housing, and a coupling assembly rotationally fixed to the deployment actuator. The catheter assembly may include a first shaft around which a compartment is defined and a distal sheath operatively connected to the carriage assembly. Movement of the carriage assembly in the longitudinal direction in the movement space may move the distal sheath between the closed condition and the open condition. The coupling assembly may have an engaged position in which rotation of the deployment actuator moves the carriage assembly, and a disengaged position in which rotation of the deployment actuator does not move the carriage assembly.
摘要翻译：用于可折叠假体心脏瓣膜的递送装置包括操作手柄和导管组件。操作手柄可以包括限定其中的移动空间的壳体，可在移动空间内沿纵向方向移动的滑架组件，联接到壳体并相对于壳体可旋转的展开致动器，以及旋转地固定到展开致动器。导管组件可以包括第一轴，围绕所述第一轴限定隔室，远侧护套可操作地连接到托架组件。滑架组件在运动空间中的纵向移动可以使远侧护套在关闭状态和打开状态之间移动。联接组件可以具有接合位置，其中展开致动器的旋转使托架组件移动，并且分离位置，其中展开致动器的旋转不移动托架组件。

8. 发明公开

EP2670352A1 ANTI-ROTATION LOCKING FEATURE 有权
标题翻译： LOCK用旋转保护
公开(公告)号：EP2670352A1
公开(公告)日：2013-12-11
申请号：EP12703394.2
申请日：2012-01-31
申请人： St. Jude Medical, Inc.
发明人： BIELEFELD, Eric E. , FURNISH, Gregory R. , BETHARDS, Christopher
IPC分类号： A61F2/24 , B25B23/142 , B25B15/02 , B25G1/04 , B25B15/00
CPC分类号： A61F2/2427 , A61F2/2466 , A61F2250/001 , B25B15/02 , B25B23/0064 , B25G1/04 , B25G3/18
摘要： An adjustment tool enables manipulation of a prosthetic anatomical device such as an annuloplasty ring. The tool includes a compression member which is operative for retarding rotation of the adjustment shaft to preclude inadvertent rotation thereof during use of the tool by the surgeon. A locking device is associated with the adjustment tool to enable the releasable attachment of the tool to the anatomical device during its adjustment by manipulation of the tool. The locking device is oriented into operative and inoperative positions by the engagement and disengagement of locking elements. A scale may be provided on the adjustment tool to assist a surgeon in determining the size or amount of adjustment to the size of the anatomical device during its adjustment.

9. 发明授权

EP2670352B1 ANTI-ROTATION LOCKING FEATURE 有权
标题翻译： LOCK用旋转保护
公开(公告)号：EP2670352B1
公开(公告)日：2016-08-10
申请号：EP12703394.2
申请日：2012-01-31
申请人： St. Jude Medical, Inc.
发明人： BIELEFELD, Eric E. , FURNISH, Gregory R. , BETHARDS, Christopher
IPC分类号： A61F2/24 , B25G1/04 , B25G3/18 , B25B15/02 , B25B23/00
CPC分类号： A61F2/2427 , A61F2/2466 , A61F2250/001 , B25B15/02 , B25B23/0064 , B25G1/04 , B25G3/18
摘要： An adjustment tool enables manipulation of a prosthetic anatomical device such as an annuloplasty ring. The tool includes a compression member which is operative for retarding rotation of the adjustment shaft to preclude inadvertent rotation thereof during use of the tool by the surgeon. A locking device is associated with the adjustment tool to enable the releasable attachment of the tool to the anatomical device during its adjustment by manipulation of the tool. The locking device is oriented into operative and inoperative positions by the engagement and disengagement of locking elements. A scale may be provided on the adjustment tool to assist a surgeon in determining the size or amount of adjustment to the size of the anatomical device during its adjustment.

10. 发明公开

EP3106131A1 ADJUSTABLE ANNULOPLASTY RING, ADJUSTMENT AND POSITIONING TOOL AND HOLDER 审中-公开
标题翻译： EINSTELLBARER ANNULOPLASTISCHER环，EINSTELL- UNDEINFÜHRRORRICHTUNGSOWIE HALTER
公开(公告)号：EP3106131A1
公开(公告)日：2016-12-21
申请号：EP16181026.2
申请日：2012-01-31
申请人： St. Jude Medical, Inc.
发明人： KOVACH, Melinda K. , CLEGG, Susan E. , MORRIS, Benjamin E. , FURNISH, Gregory R. , BIELEFELD, Eric E. , FURNISH, Simon M.
IPC分类号： A61F2/24 , B25B23/142 , B25B15/02 , B25G1/04 , B25G3/18
CPC分类号： A61F2/2466 , A61B5/1076 , A61F2/2445 , A61F2/2448 , A61F2/2496 , A61F2250/001 , A61F2250/006 , A61F2250/0065 , A61F2250/0089 , A61F2250/0097 , B25B15/02 , B25B23/142 , B25G1/046 , B25G3/18
摘要： An adjustable prosthetic anatomical holder system is disclosed. The system is adaptable for use in cardiac surgery and may include an adjustable annuloplasty ring, a ring holder, and a positioning handle. The adjustable annuloplasty ring holder facilitates placement and adjustment of the annuloplasty ring during a cardiac surgical procedure. An optional positioning handle holds the adjustable annuloplasty ring during placement and suturing of the ring. The ring holder is constructed from two members that are slidably fit together in telescopic arrangement to accommodate adjustment of the ring size.
摘要翻译：公开了一种可调节的假体解剖支架系统。该系统适用于心脏手术，并且可以包括可调环形成形术环，环保持器和定位手柄。可调环形成形术环支架有助于心脏外科手术期间环形成形术环的放置和调整。可选的定位手柄在环的放置和缝合期间保持可调节瓣环成形术环。环形支架由两个构件构成，两个构件可伸缩地可滑动地配合在一起以适应环尺寸的调节。

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