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1. 发明申请

WO2008098101A3 DEVICE AND METHOD FOR HIGH INTENSITY FOCUSED ULTRASOUND ABLATION WITH ACOUSTIC LENS 审中-公开
标题翻译：高强度聚焦超声波吸收与声学透镜的装置和方法
公开(公告)号：WO2008098101A3
公开(公告)日：2008-11-20
申请号：PCT/US2008053263
申请日：2008-02-07
申请人： ST JUDE MEDICAL ATRIAL FIBRILL , SLIWA JOHN W , GOETZ JOHN P , MA ZHENYI , CALLAGHAN FRANK , CICIARELLI TIMOTHY E , TENG JENNIFER , MORSE STEPHEN A
发明人： SLIWA JOHN W , GOETZ JOHN P , MA ZHENYI , CALLAGHAN FRANK , CICIARELLI TIMOTHY E , TENG JENNIFER , MORSE STEPHEN A
IPC分类号： A61B8/14
CPC分类号： A61N7/02 , A61N2007/0056 , A61N2007/006 , A61N2007/0078
摘要： A high intensity focused ultrasound transducer (10) includes an ultrasonic emitter (12) having a surface (16) that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens (14) acoustically coupled to surface (16) in the beam path of the ultrasonic energy, such that the lens can direct ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf (30), a heat sink, or an acoustic matching layer (28), to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, surface (16) is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.
摘要翻译：高强度聚焦超声换能器（10）包括具有沿着光束路径发射超声波能量的表面（16）的超声波发射器（12），至少一个声学耦合到表面（16）的低衰减聚合物超声波透镜（14）超声能量的光束路径，使得透镜可以在至少一个方向上引导超声波能量，以及至少一个应力消除特征，例如切口（30），散热器或声匹配层（28），以减轻换能器内的热膨胀失配应力。为了简化制造，表面（16）通常是平坦的或单调的曲线。透镜可以采取各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。预期至少一个超声波透镜相对于超声发射器的任何取向和定位。通过模制，铸造或热成型镜片进一步简化制造。

2. 发明申请

WO2008098099A3 HIGH INTENSITY FOCUSED ULTRASOUND TRANSDUCER WITH ACOUSTIC LENS 审中-公开
标题翻译：高强度聚焦超声波传感器与声学镜头
公开(公告)号：WO2008098099A3
公开(公告)日：2008-11-20
申请号：PCT/US2008053260
申请日：2008-02-07
申请人： ST JUDE MEDICAL ATRIAL FIBRILL , SLIWA JOHN W , GOETZ JOHN P , MA ZHENYI , TENG JENNIFER , MORSE STEPHEN A , CALLAGHAN FRANK , CICIARELLI TIMOTHY E
发明人： SLIWA JOHN W , GOETZ JOHN P , MA ZHENYI , TENG JENNIFER , MORSE STEPHEN A , CALLAGHAN FRANK , CICIARELLI TIMOTHY E
IPC分类号： A61B8/14
CPC分类号： A61N7/02 , A61B8/4272 , A61B17/2251
摘要： A high intensity focused ultrasound transducer (10) includes an ultrasonic emitter (12) having a surface (16) that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens (14) acoustically coupled to surface (16) in the beam path of the ultrasonic energy, such that the lens can direct ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf (30), a heat sink, or an acoustic matching layer (28), to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, surface (16) is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.
摘要翻译：高强度聚焦超声波换能器（10）包括具有沿着光束路径发射超声波能量的表面（16）的超声波发射器（12），至少一个声学耦合到表面（16）的低衰减聚合物超声波透镜（14）超声能量的光束路径，使得透镜可以在至少一个方向上引导超声波能量，以及至少一个应力消除特征，例如切口（30），散热器或声匹配层（28），以减轻换能器内的热膨胀失配应力。为了制造简单，表面（16）通常是平坦的或单调的曲线。透镜可以采用各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。预期至少一个超声波透镜相对于超声发射器的任何取向和定位。通过模制，铸造或热成型镜片进一步简化制造。

3. 发明申请

WO2009085485A2 TEMPLATE SYSTEM AND METHODS 审中-公开
标题翻译：模式系统和方法
公开(公告)号：WO2009085485A2
公开(公告)日：2009-07-09
申请号：PCT/US2008084557
申请日：2008-11-24
申请人： ST JUDE MEDICAL ATRIAL FIBRILL , SLIWA JOHN W , EBY THOMAS B
发明人： SLIWA JOHN W , EBY THOMAS B
IPC分类号： A61B18/14
CPC分类号： A61B18/18 , A61B8/12 , A61B8/4209 , A61B8/4236 , A61B8/4245 , A61B8/4281 , A61B8/445 , A61B18/148 , A61B18/1815 , A61B18/20 , A61B2017/00867 , A61B2018/00011 , A61B2018/00273 , A61B2018/00291 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2090/378 , A61B2218/002 , C08L2201/12
摘要： Template systems and methods for various procedures (e.g., tissue ablation procedures) are disclosed. An exemplary template system (10) comprises a track (12) having at least one suction port (22). The at least one suction port (22) anchors the track (12) to a tissue after the track (12) is positioned adjacent a target area. The template system (10) may further comprise a transducer (14) operatively associated with the track (12). Exemplary transducers include imaging transducers and ablating transducers. The transducer (14) is guided by the track (12) adjacent the target area while the transducer (14) is moved along the track (12) for a procedure. One or more umbilical (16a, 16b) may provide a conduit to the track (12) and/or transducer (14) so that the template system (10) may be positioned in a patient's body (e.g., for a procedure on the patient's heart) and operated remotely by a physician or other user from outside of the patient's body.
摘要翻译：公开了用于各种程序（例如，组织消融程序）的模板系统和方法。示例性模板系统（10）包括具有至少一个吸入口（22）的轨道（12）。所述至少一个吸入口（22）在所述轨道（12）邻近目标区域定位之后将轨道（12）锚固到组织。模板系统（10）还可以包括与轨道（12）可操作地相关联的换能器（14）。示例性换能器包括成像换能器和消融换能器。传感器（14）由邻近目标区域的轨道（12）引导，同时换能器（14）沿着轨道（12）移动以用于过程。一个或多个脐带（16a，16b）可以向轨道（12）和/或换能器（14）提供导管，使得模板系统（10）可以定位在患者体内（例如，用于患者的身体上的程序心脏），并由医生或其他用户从患者身体外部远程操作。

4. 发明申请

WO2008083043A3 MEDICAL DEVICE HAVING A BIMATERIAL VALVE 审中-公开
标题翻译：医疗设备有一个双气门
公开(公告)号：WO2008083043A3
公开(公告)日：2008-08-28
申请号：PCT/US2007088424
申请日：2007-12-20
申请人： ST JUDE MEDICAL ATRIAL FIBRILL , CROWE JOHN E , SLIWA JOHN W
发明人： CROWE JOHN E , SLIWA JOHN W
IPC分类号： A61B18/04
CPC分类号： A61N7/022 , A61B17/2202 , A61B18/02 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2018/00011 , A61B2018/00023 , A61B2018/00744 , A61B2018/00791 , A61N2007/0078
摘要： Medical devices using fluid or cooling fluids having one or more bimaterial valves positioned at each point of flow control to control the flow of a fluid in response to temperature changes. In particular, devices for ablating tissue having multiple ablation elements or cells include one or more bimaterial valves positioned within or near the ablation cells. The bimaterial valves respond to temperature changes by adjusting the flow rate of a fluid through the valve.
摘要翻译：使用流体或冷却流体的医疗设备具有位于每个流量控制点处的一个或多个双材料阀，以响应于温度变化来控制流体的流动。特别地，用于消融具有多个消融元件或细胞的组织的装置包括位于消融细胞内或附近的一个或多个双材料瓣膜。双材料阀通过调节通过阀的流体的流量来响应温度变化。

5. 发明公开

EP2445410A4 APPARATUS AND METHODS FOR ACOUSTIC MONITORING OF ABLATION PROCEDURES 审中-公开
标题翻译：装置及监测方法ACOUSTICABLATIONSVORGÄNGEN
公开(公告)号：EP2445410A4
公开(公告)日：2015-06-03
申请号：EP10838040
申请日：2010-09-16
申请人： ST JUDE MEDICAL ATRIAL FIBRILL
发明人： SLIWA JOHN W , MA ZHENYI , GOETZ JOHN P , MORSE STEPHEN A
IPC分类号： A61B8/00
CPC分类号： A61B18/1492 , A61B7/00 , A61B8/0833 , A61B8/0858 , A61B8/0883 , A61B8/12 , A61B8/4472 , A61B8/4483 , A61B8/462 , A61B8/463 , A61B8/5215 , A61B2017/00106 , A61B2018/00577 , A61B2018/00791 , A61B2018/00839 , A61B2018/1861 , A61B2090/065

6. 发明公开

EP2445421A4 SELF-AIMING DIRECTABLE ACOUSTIC TRANSDUCER ASSEMBLY FOR INVASIVE MEDICAL DEVICE APPLICATIONS 失效
标题翻译： SELBSTABZIELENDE AUSRICHTBARE AKUSTISCHE TRANSDUCER-ANORDNUNGFÜRINVASIVE MEDIZINVORRICHTUNGSANWENDUNGEN
公开(公告)号：EP2445421A4
公开(公告)日：2015-06-03
申请号：EP10838041
申请日：2010-09-16
申请人： ST JUDE MEDICAL ATRIAL FIBRILL
发明人： SLIWA JOHN W , MORSE STEPHEN
IPC分类号： A61B17/22 , A61B8/00 , A61N7/00
CPC分类号： A61B8/12 , A61B5/6885 , A61B8/085 , A61B8/4254 , A61B8/429 , A61B8/445 , A61B18/1492 , A61B2090/378 , A61B2090/3784 , A61M37/0092 , H04R17/00
摘要： A directable acoustic transducer assembly is presented for use in a medical insertion device (MID). In an embodiment, the assembly aims an acoustic signal in response to a sensed or detected force or load imposed on the MID. The directable acoustic transducer assembly includes a switch array and a plurality of directional acoustic transducer elements. The switch array responds to the force or load and activates the directional acoustic transducer elements closest to the source of the force or load. The switch array may include a plurality of switches, at least one of which responses to a force or load and may activate directional acoustic transducer elements having a target tissue in the field of view. The assembly includes embodiments that are responsive to various loads. A directable acoustic transducer assembly may be part of a diagnostic and/or therapeutic system, such as an RF ablation system.
摘要翻译：呈现用于医疗插入装置（MID）的可直接声学换能器组件。在一个实施例中，组件响应于施加在MID上的感测或检测到的力或负载来瞄准声信号。可直接声换能器组件包括开关阵列和多个定向声换能器元件。开关阵列响应力或负载，并激活最靠近力或负载源的定向声换能器元件。开关阵列可以包括多个开关，其中至少一个响应于力或负载，并且可以激活在视场中具有目标组织的定向声换能器元件。组件包括响应于各种负载的实施例。可指示的声换能器组件可以是诊断和/或治疗系统的一部分，例如RF消融系统。

7. 发明公开

EP2459074A4 METHODS AND APPARATUS FOR DETECTING AND MAPPING TISSUE INTERFACES 有权转让
标题翻译：哥伦比亚革命联合会（VERFAHREN UND VORRICHTUNG ZUM ERFASSEN UND ABBILDEN VON GEWEBESCHNITTSTELLEN
公开(公告)号：EP2459074A4
公开(公告)日：2013-05-15
申请号：EP10805129
申请日：2010-07-30
申请人： ST JUDE MEDICAL ATRIAL FIBRILL
发明人： SHAQUER CEM , SLIWA JOHN W , MA ZHENYI , DANDO JEREMY D
IPC分类号： A61B8/14
CPC分类号： A61B8/12 , A61B6/503 , A61B6/541 , A61B8/0883 , A61B8/4245 , A61B8/445 , A61B8/543 , A61B18/1492 , A61B2017/00106 , A61B2018/00357 , A61B2018/00577 , A61B2034/2051 , A61N7/022
摘要： A device for measuring a spatial location of a tissue surface, such as the interface between different types of tissues or between tissue and body fluids, generally includes an elongate catheter body having a distal end portion, a plurality of localization elements carried by the distal end portion, and at least one pulse-echo acoustic element carried by the distal end portion. The localization elements allow the catheter to be localized (e.g., position and/or orientation) within a localization field, while the acoustic element allows for the detection of tissue surfaces where incoming acoustic energy will reflect towards the acoustic element. A suitable controller can determine the location of the detected tissue surface from the localization of the distal end portion of the catheter body. Tissue thicknesses can be derived from the detected locations of multiple (e.g., near and far) tissue surfaces. Maps and models of tissue thickness can also be generated.
摘要翻译：用于测量组织表面（例如不同类型的组织之间或组织与体液之间的界面）的空间位置的装置通常包括具有远端部分的细长导管主体，多个定位元件由远端以及至少一个由远端部分携带的脉冲 - 回声声学元件。定位元件允许导管在定位区域内定位（例如，位置和/或取向），而声学元件允许检测组织表面，其中进入的声能将朝着声学元件反射。合适的控制器可以根据导管主体的远端部分的定位来确定检测到的组织表面的位置。组织厚度可以从多个（例如，近和远）组织表面的检测位置导出。还可以生成组织厚度的地图和模型。

8. 发明公开

EP2112906A4 DEVICE AND METHOD FOR HIGH INTENSITY FOCUSED ULTRASOUND ABLATION WITH ACOUSTIC LENS 有权
标题翻译：装置和方法具有高强度聚焦超声消融使用声透镜
公开(公告)号：EP2112906A4
公开(公告)日：2011-03-30
申请号：EP08729243
申请日：2008-02-07
申请人： ST JUDE MEDICAL ATRIAL FIBRILL
发明人： SLIWA JOHN W , GOETZ JOHN P , MA ZHENYI , CALLAGHAN FRANK , CICIARELLI TIMOTHY E , TENG JENNIFER , MORSE STEPHEN A
IPC分类号： A61B8/14
CPC分类号： A61N7/02 , A61N2007/0056 , A61N2007/006 , A61N2007/0078

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