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1. 发明申请

WO2012023979A2 A DEVICE FOR COLLAPSING AND LOADING A HEART VALVE INTO A MINIMALLY INVASIVE DELIVERY SYSTEM 审中-公开
标题翻译：用于将心脏瓣膜收集并装载到最小的自动递送系统中的装置
公开(公告)号：WO2012023979A2
公开(公告)日：2012-02-23
申请号：PCT/US2011001445
申请日：2011-08-17
申请人： ST JUDE MEDICAL , DALE THEODORE P , CHALEKIAN AARON J , GLAZIER VALERIE J , WANG HUISUN
发明人： DALE THEODORE P , CHALEKIAN AARON J , GLAZIER VALERIE J , WANG HUISUN
IPC分类号： A61F2/84
CPC分类号： A61F2/2427 , A61F2/2418 , A61F2002/9522 , Y10T29/49927 , Y10T29/53657 , Y10T29/53796 , Y10T29/53843 , Y10T29/53852 , Y10T29/539
摘要： A device is provided for collapsing a stented bioprosthetic valve, including first section and second sections, each spanning between first and second ends of the device. The second section of the device is associated with the first section to at least partially enclose an internal cavity formed by the first and second sections, the internal cavity tapering from an open insertion portion at a first end of the device to an open exit portion at a second end of the device. The insertion portion has a larger dimension than the exit portion. When the first section and second section are substantially enclosing the internal cavity, a stented bioprosthetic valve may be inserted into the insertion portion and collapsed as it is moved toward and through the exit portion. The valve may then be loaded on an apparatus for insertion into the body.
摘要翻译：提供了一种装置，用于折叠支架的生物假肢瓣膜，包括第一部分和第二部分，每个跨越装置的第一和第二端之间。该装置的第二部分与第一部分相关联，以至少部分地包围由第一和第二部分形成的内部空腔，内部空腔从装置的第一端处的开口插入部分逐渐变细到开放的出口部分设备的第二端。插入部分具有比出口部分更大的尺寸。当第一部分和第二部分基本上包围内部空腔时，支架的生物假体瓣膜可以插入插入部分中，并且当它朝向和穿过出口部分移动时收缩。然后可以将阀装载到用于插入体内的装置上。

2. 发明申请

WO2012036742A2 ASSEMBLY AND METHOD FOR LOADING A SELF-EXPANDING COLLAPSIBLE HEART VALVE 审中-公开
标题翻译：装载可自动扩张的心脏瓣膜的组装和方法
公开(公告)号：WO2012036742A2
公开(公告)日：2012-03-22
申请号：PCT/US2011001598
申请日：2011-09-16
申请人： ST JUDE MEDICAL CARDIOLOGY DIV , JOHNSON MICHAEL A , GLAZIER VALERIE J , WANG HUISUN , ST JUDE MEDICAL
发明人： JOHNSON MICHAEL A , GLAZIER VALERIE J , WANG HUISUN
IPC分类号： A61F2/24 , B23P19/00
CPC分类号： A61F2/2436 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2002/9522 , A61F2210/0014 , A61F2210/0028 , A61F2250/0039 , B23P11/025 , Y10T29/49863 , Y10T29/49865 , Y10T29/49927 , Y10T29/53909 , Y10T137/0402
摘要： An assembly for collapsing a prosthetic heart valve includes a compression member and a pusher member. The compression member has a first open end with a first diameter, a second open end with a second diameter less than the first diameter, and a tapered wall between the first open end and the second open end. The pusher member has a base adapted to engage an end of the valve. The pusher member and the compression member are movable relative to one another between an initial position in which the base of the pusher member is relatively far from the first open end of the compression member and an operative position in which the base of the pusher member is relatively close to the first open end of the compression member. Movement of the pusher and compression members from the initial position to the operative position radially compresses the valve.
摘要翻译：用于塌陷假体心脏瓣膜的组件包括压缩构件和推动构件。压缩构件具有第一直径的第一开口端，具有小于第一直径的第二直径的第二开口端以及第一开口端和第二开口端之间的锥形壁。推动器构件具有适于接合阀的端部的基座。推动器构件和压缩构件可以在其中推动器构件的基部相对于压缩构件的第一开口端相对较远的初始位置和推动构件的基座的操作位置之间相对于彼此移动相对靠近压缩构件的第一开口端。推动器和压缩构件从初始位置到操作位置的移动径向地压缩阀。

3. 发明申请

WO2012036740A3 RETAINERS FOR TRANSCATHETER HEART VALVE DELIVERY SYSTEMS 审中-公开
标题翻译： TRANSCATHETER心瓣输送系统的保持器
公开(公告)号：WO2012036740A3
公开(公告)日：2012-07-05
申请号：PCT/US2011001596
申请日：2011-09-16
申请人： ST JUDE MEDICAL CARDIOLOGY DIV , WANG HUISUN , GLAZIER VALERIE J , DALY JACOB J , ST JUDE MEDICAL
发明人： WANG HUISUN , GLAZIER VALERIE J , DALY JACOB J
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/966 , A61F2002/9665 , A61F2230/0054 , A61M2025/0681
摘要： A delivery device 10 for a collapsible prosthetic heart valve includes a catheter assembly 16 including a shaft 26 around which a compartment 23 is defined, the compartment 23 being adapted to receive the valve in an assembled condition, and a retainer 30 including a pusher 32 and a holder 34 adapted to retain a stent portion 106 of the valve. The catheter assembly 16 also includes a distal sheath 24 adapted to selectively cover and uncover the compartment 23 and the valve, the distal sheath 24 extending around the shaft 26 at least when the distal sheath 24 covers the compartment 23. The pusher 32 includes one or more recesses 40 in a retention edge 33 thereof, each recess 40 being adapted to receive a junction 107 at an end of the stent portion 106 of the valve. The holder 34 includes one or more elongated ribs 50, each rib 50 being adapted to fit into a cell opening 108 of the stent portion 106 of the valve.
摘要翻译：用于可折叠的假体心脏瓣膜的输送装置10包括导管组件16，导管组件16包括轴26，隔室23围绕该轴26被限定，隔间23适于在组装状态下容纳阀，以及保持器30，其包括推动器32和适于保持阀的支架部分106的保持器34。导管组件16还包括远端护套24，其适于选择性地覆盖和露出隔室23和瓣膜，至少当远端护套24覆盖隔室23时，远侧护套24围绕轴26延伸。推动器32包括一个或在其保持边缘33中具有更多的凹部40，每个凹部40适于在瓣膜的支架部分106的端部处容纳接合部107。保持器34包括一个或多个细长肋50，每个肋50适于装配到瓣膜的支架部分106的细胞开口108中。

4. 发明申请

WO2012023981A2 TIP FOR MEDICAL IMPLANT DELIVERY SYSTEM 审中-公开
标题翻译：医用植物输送系统提示
公开(公告)号：WO2012023981A2
公开(公告)日：2012-02-23
申请号：PCT/US2011001447
申请日：2011-08-17
申请人： ST JUDE MEDICAL , WANG HUISUN , GLAZIER VALERIE J
发明人： WANG HUISUN , GLAZIER VALERIE J
IPC分类号： A61F2/24 , A61F2/84
CPC分类号： A61F2/2436 , A61F2/2433 , A61F2/966 , A61F2250/0018 , A61F2250/0019
摘要： A delivery system for delivering and deploying a medical implant, such as a prosthetic heart valve, includes an elongated support member, a sheath, and a tip. The sheath is movable relative to the elongated support member between a distal position overlying the medical implant and a proximal position exposing the medical implant for release from the delivery system. The tip is attached to the elongated support member and is positioned at a distal end of the sheath when the sheath is in the distal position. The tip has a compressed condition and an expanded condition, and a maximum diameter in the expanded condition that is larger than the outer diameter of the sheath.
摘要翻译：用于递送和部署诸如假体心脏瓣膜的医疗植入物的递送系统包括细长的支撑构件，护套和尖端。护套可以在覆盖医疗植入物的远侧位置和暴露医疗植入物以远离输送系统的近端位置之间相对于细长支撑构件移动。当护套处于远侧位置时，尖端附接到细长的支撑构件并且定位在护套的远端。尖端具有压缩状态和膨胀状态，并且在膨胀状态下的最大直径大于护套的外径。

5. 发明申请

WO2012106491A8 SYSTEM AND METHOD FOR LOADING A COLLAPSIBLE HEART VALVE INTO A DELIVERY DEVICE 审中-公开
标题翻译：将可收缩心瓣装载到递送装置中的系统和方法
公开(公告)号：WO2012106491A8
公开(公告)日：2013-08-22
申请号：PCT/US2012023576
申请日：2012-02-02
申请人： ST JUDE MEDICAL , ALKHATIB YOUSEF F , DALY JACOB J , GLAZIER VALERIE J , HILLUKKA BRETT A , THOMAS RALPH J , WANG HUISUN
发明人： ALKHATIB YOUSEF F , DALY JACOB J , GLAZIER VALERIE J , HILLUKKA BRETT A , THOMAS RALPH J , WANG HUISUN
IPC分类号： A61F2/24 , A61F2/00 , A61F2/95 , A61F2/97
CPC分类号： A61F2/2427 , A61F2/0095 , A61F2/2412 , A61F2/2436 , A61F2/97 , A61F2002/9522 , A61F2250/0039 , Y10T29/49826 , Y10T29/53909 , Y10T29/53943
摘要： An assembly (200) for collapsing a self - expanding prosthetic heart valve includes a compression member (202) a support member (204) and a constricting member (300). The compression member has a tapered wall between its first open end and its second open end, the tapered wall defining an open space adapted to receive the valve. The support member has a base (220) and a recess (226) adapted to receive an end of the valve. The support member and the compression member are movable toward one another to compress the valve and push it through a relatively small aperture in the second open end of the compression member. The second end of the constricting member is sized to receive the compressed valve from the second open end of the compression member for loading into a delivery device.
摘要翻译：用于塌陷自膨胀假体心脏瓣膜的组件（200）包括压缩构件（202），支撑构件（204）和收缩构件（300）。压缩构件在其第一开口端和其第二开口端之间具有锥形壁，锥形壁限定适于接收阀的开放空间。支撑构件具有适于容纳阀的端部的底座（220）和凹部（226）。支撑构件和压缩构件可彼此移动以压缩阀并将其推压通过压缩构件的第二开口端中的相对小的孔。收缩构件的第二端的尺寸被设计成从压缩构件的第二开口端接收压缩的阀，以便装载到输送装置中。

6. 发明申请

WO2011025543A3 MONORAIL SYSTEM FOR VASCULAR CLOSURE DEVICE AND METHODS 审中-公开
标题翻译：用于血管闭合装置的MONORAIL系统和方法
公开(公告)号：WO2011025543A3
公开(公告)日：2011-04-21
申请号：PCT/US2010002375
申请日：2010-08-30
申请人： ST JUDE MEDICAL PUERTO RICO , PIPENHAGEN CATHERINE A , GLAZIER VALERIE J , KRAMER SCOTT A
发明人： PIPENHAGEN CATHERINE A , GLAZIER VALERIE J , KRAMER SCOTT A
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00654 , A61B2017/00672 , A61B2017/00778 , A61M2025/0183
摘要： A tissue puncture closure assembly including a wire assembly and first and second devices. The wire assembly includes a first wire member and a second wire member that each include a distal end portion and a proximal end portion. At least portions of the second wire member are arranged side-by-side with the first wire member. The distal end portion of the first wire member is connected to the distal end portion of the second wire member, and a proximal end portion of the first wire member is disconnected from the proximal end portion of the second wire member. The first device is operable to advance over the first wire member. The second device is operable to advance over the second wire member.
摘要翻译：一种组织穿刺闭合组件，包括线组件和第一和第二装置。线组件包括第一线构件和第二线构件，每个包括远端部分和近端部分。第二线构件的至少一部分与第一线构件并排配置。第一线构件的前端部与第二线构件的前端部连接，第一线构件的基端部与第二线构件的基端部分断开。第一装置可操作以在第一线构件上前进。第二装置可操作以在第二线构件上前进。

7. 发明申请

WO2013166356A3 DEVICES AND METHODS FOR TRANSCATHETER HEART VALVE DELIVERY 审中-公开
标题翻译：用于输送心脏瓣膜输送的装置和方法
公开(公告)号：WO2013166356A3
公开(公告)日：2014-03-27
申请号：PCT/US2013039407
申请日：2013-05-03
申请人： ST JUDE MEDICAL , ST JUDE MEDICAL CARDIOLOGY DIV
发明人： MORRIS BENJAMIN E , FURNISH GREGORY R , BIELEFELD ERIC E , THOMAS RALPH J , LE KHOI A , GLAZIER VALERIE J , KNIPPEL BRADLEY C
IPC分类号： A61F2/24 , A61F2/95 , A61F2/962
CPC分类号： A61F2/2436 , A61F2/962 , A61F2002/9517
摘要： A delivery device for a collapsible prosthetic heart valve includes an operating handle and a catheter assembly. The operating handle may include a housing defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, a deployment actuator coupled to the housing and rotatable relative to the housing, and a coupling assembly rotationally fixed to the deployment actuator. The catheter assembly may include a first shaft around which a compartment is defined and a distal sheath operatively connected to the carriage assembly. Movement of the carriage assembly in the longitudinal direction in the movement space may move the distal sheath between the closed condition and the open condition. The coupling assembly may have an engaged position in which rotation of the deployment actuator moves the carriage assembly, and a disengaged position in which rotation of the deployment actuator does not move the carriage assembly.
摘要翻译：用于可折叠假体心脏瓣膜的递送装置包括操作手柄和导管组件。操作手柄可以包括限定其中的移动空间的壳体，可在移动空间内沿纵向方向移动的滑架组件，联接到壳体并相对于壳体可旋转的展开致动器，以及旋转地固定到展开致动器。导管组件可以包括第一轴，围绕所述第一轴限定隔室，远侧护套可操作地连接到托架组件。滑架组件在运动空间中的纵向移动可以使远侧护套在关闭状态和打开状态之间移动。联接组件可以具有接合位置，其中展开致动器的旋转使托架组件移动，并且分离位置，其中展开致动器的旋转不移动托架组件。

8. 发明专利

BR112013003610A2 sistema de colocação para colocar e implantar um implante médico 未知
公开(公告)号：BR112013003610A2
公开(公告)日：2016-08-16
申请号：BR112013003610
申请日：2011-08-17
申请人： ST JUDE MEDICAL
发明人： WANG HUISUN , GLAZIER VALERIE J
IPC分类号： A61F2/24
摘要： sistema de colocação para colocar e implantar um implante médico. um sistema de colocação para colocar e implantar um implante médico, tal como uma válvula cardíaca protética, incluindo um membro de suporte alongado, um envoltório e uma ponta. o envoltório é móvel em relação ao membro de suporte alongado, entre uma posição distal sobrepondo-se ao implante médico, e uma posição proximal, expondo o implante médico a liberação do sistema de colocação. a ponta é fixada ao membro de suporte alongado e é posicionada em uma extremidade distal do envoltório, quando o envoltório está na posição distal. a ponta tem uma condição comprimida e uma condição expandida, e um diâmetro máximo na condição expandida, que é maior do que o diâmetro externo do envoltório.

9. 发明专利

AU2012212188A1 System and method for loading a collapsile heart valve into a delivery device 未知
公开(公告)号：AU2012212188A1
公开(公告)日：2013-08-29
申请号：AU2012212188
申请日：2012-02-02
申请人： ST JUDE MEDICAL
发明人： ALKHATIB YOUSEF F , DALY JACOB J , GLAZIER VALERIE J , HILLUKKA BRETT A , THOMAS RALPH J , WANG HUISUN
IPC分类号： A61F2/24 , A61F2/00 , A61F2/95 , A61F2/97
摘要： An assembly (200) for collapsing a self - expanding prosthetic heart valve includes a compression member (202) a support member (204) and a constricting member (300). The compression member has a tapered wall between its first open end and its second open end, the tapered wall defining an open space adapted to receive the valve. The support member has a base (220) and a recess (226) adapted to receive an end of the valve. The support member and the compression member are movable toward one another to compress the valve and push it through a relatively small aperture in the second open end of the compression member. The second end of the constricting member is sized to receive the compressed valve from the second open end of the compression member for loading into a delivery device.

10. 发明专利

CA2842074A1 SYSTEM FOR LOADING A COLLAPSIBLE HEART VALVE 未知
公开(公告)号：CA2842074A1
公开(公告)日：2013-01-31
申请号：CA2842074
申请日：2012-07-26
申请人： ST JUDE MEDICAL CARDIOLOGY DIV
发明人： HILLUKKA BRETT A , LE KHOI A , THOMAS RALPH J , GLAZIER VALERIE J
IPC分类号： A61F2/24 , A61F2/00
摘要： An assembly (200) for collapsing a self-expanding prosthetic heart valve (100) includes a compression member (202), a support member (204), a constricting member (300), and a spacer (270) which may be used for smaller sized heart valves. The compression member has a tapered wall (206) between its first open end and its second open end, the tapered wall defining an open space adapted to receive the heart valve. The support member has a base (220) and a recess (226) adapted to receive an end of the heart valve. The support member and the compression member are movable toward one another to compress the heart valve and push it through a relatively small aperture (218) in the second open end of the compression member. The second end (306) of the constricting member is sized to receive the compressed heart valve from the second open end of the compression member for loading into a delivery device (10).

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