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1. 发明申请

WO2003099123A1 SYSTEM AND METHOD FOR THE EXTRACTION AND MONITORING OF A BIOLOGICAL FLUID 审中-公开
标题翻译：用于提取和监测生物流体的系统和方法
公开(公告)号：WO2003099123A1
公开(公告)日：2003-12-04
申请号：PCT/US2003/016315
申请日：2003-05-22
申请人： SPECTRX, INC. , FAUPEL, Mark , LINCOLN, Danny
发明人： FAUPEL, Mark , LINCOLN, Danny
IPC分类号： A61B5/15
CPC分类号： A61B5/155 , A61B5/14514 , A61B5/150022 , A61B5/150099 , A61B5/150213 , A61B5/150229 , A61B5/150343 , A61B5/150358 , A61B5/150969 , A61B10/0045 , A61B2010/008
摘要： Systems and methods use extraction devices for extracting and monitoring biological fluids of patients. The systems and methods involve creating an opening in the biological tissue of the patient and placing a sampling aperture of the extraction device over the opening. The sampling aperture is defined in a contact surface of the extraction device that is placed into contact with the tissue of the patient. A pump of the extraction device such as a depressible bulb sealed to the body is charged to create a vacuum between the pump through a sampling channel to the sampling aperture, and the vacuum draws the biological fluid from the tissue opening into the sampling channel. An access point is exposed to the sampling channel, and the sample of fluid may be accessed from the access point. The access point may be an extraction opening covered by an access door, and the access door is opened to access the sample. Alternatively, the access point may be electrodes extending into the sampling channel where the electrodes are connectable to a fluid analyzer device.
摘要翻译：系统和方法使用提取装置来提取和监测患者的生物液体。所述系统和方法涉及在患者的生物组织中产生开口并将提取装置的采样孔放置在开口上。取样孔限定在提取装置的与患者组织接触的接触表面中。对诸如密封到身体的可压迫的灯泡的提取装置的泵进行充电以在泵通过采样通道到采样孔之间产生真空，并且真空将生物流体从组织开口吸入采样通道。接入点暴露于采样通道，可以从接入点访问流体样本。接入点可以是由进入门覆盖的提取开口，并且访问门被打开以访问样本。或者，接入点可以是延伸到采样通道中的电极，其中电极可连接到流体分析器装置。

2. 发明申请

WO2008157351A2 PROGRESSIVE CAVITY PROPAGATION PUMP 审中-公开
标题翻译：渐进式传播泵
公开(公告)号：WO2008157351A2
公开(公告)日：2008-12-24
申请号：PCT/US2008/066914
申请日：2008-06-13
申请人： SMITHS MEDICAL ASD, INC. , AMLEY, Joseph , LACROSS, Steven , LINCOLN, Danny , MACK, Stanley, Paul , VICK, Stephen, L. , PATZER, Charles, R.
发明人： AMLEY, Joseph , LACROSS, Steven , LINCOLN, Danny , MACK, Stanley, Paul , VICK, Stephen, L. , PATZER, Charles, R.
IPC分类号： A61M5/142 , F04B43/00 , F04B43/02 , F04B43/08 , F04B43/12
CPC分类号： A61M5/14228 , A61M5/14232 , F04B43/12
摘要： A pump (50) is provided that includes a body (52) made at least partially of an elastomeric material and an inlet port (62) and an outlet port (64), with each port (62, 64) being coupled to the body (52). The pump (50) further includes a flow passage (66) formed in the body (52) and extending between the inlet port (62) and the outlet port (64), with at least a portion of the flow passage (66) being normally closed and with the inlet port (62) being fluidicly uncoupled with the outlet port (64) when the pump (50) is in a free-state condition. An actuating device (76) is coupled to the body (52) and is operable for sequentially deforming the body (52) to create a cavity (88a) within the normally closed portion of the flow passage (66), the cavity (66) being in fluid communication with the iniet port (62), thereby drawing a packet of fluid (90a) from the inlet port (62) into the cavity and propagating the cavity and the packet of fluid contained therein toward the outlet port (64).
摘要翻译：提供了一种泵（50），其包括至少部分地由弹性体材料制成的主体（52）和入口（62）和出口（64），每个端口（62,64）联接到主体（52）。泵（50）还包括形成在主体（52）中并在入口（62）和出口（64）之间延伸的流动通道（66），流动通道（66）的至少一部分是当泵（50）处于自由状态时，通常关闭并且入口（62）与出口（64）流体地分离。致动装置（76）联接到主体（52）并且可操作以使主体（52）顺序变形，以在流动通道（66）的常闭部分内形成空腔（88a），空腔（66）与所述入口端口（62）流体连通，从而从所述入口端口（62）将一包流体（90a）从所述空腔中拉出并且将所述空腔和包含在其中的流体包向所述出口（64）传播。

3. 发明公开

EP1181582A2 METHOD FOR PROTECTING A FIBER OPTIC PROBE AND THE RESULTING FIBER OPTIC PROBE 审中-公开
标题翻译：光纤末端与保护方法
公开(公告)号：EP1181582A2
公开(公告)日：2002-02-27
申请号：EP99974262.0
申请日：1999-11-02
申请人： SPECTRX, Inc.
发明人： LINCOLN, Danny , HARRELL, Tim , KUMAR, Krishna , PAPP, Joseph , FARQUHAR, David
IPC分类号： G02B1/00
CPC分类号： G02B6/04 , A61B2018/2211
摘要： A fiber optic probe (110) is provided that includes a housing (160), at least one optical fiber (120) disposed within the housing, one end of each of the at least one optical fiber being disposed adjacent an opening in the housing forming a probe face, a binding agent (130) that binds the at least one optical fiber within the housing, and a protective coating (150) sealingly covering the probe face to prevent contaminants from contacting the at least one optical fiber. A method for protecting a fiber optic probe having a housing, at least one optical fiber being disposed adjacent an opening in the housing forming a probe face, and a binding agent that binds the at least one optical fiber within the housing, includes polishing the probe face to create a substantially flat probe face, cleaning the probe face after polishing the probe face and sealing the probe face with a protective coating.

4. 发明公开

EP1513448A1 SYSTEM AND METHOD FOR THE EXTRACTION AND MONITORING OF A BIOLOGICAL FLUID 审中-公开
标题翻译：系统和方法提取和监测的生物流体
公开(公告)号：EP1513448A1
公开(公告)日：2005-03-16
申请号：EP03755455.7
申请日：2003-05-22
申请人： SPECTRX, Inc.
发明人： FAUPEL, Mark , LINCOLN, Danny
IPC分类号： A61B5/15
CPC分类号： A61B5/155 , A61B5/14514 , A61B5/150022 , A61B5/150099 , A61B5/150213 , A61B5/150229 , A61B5/150343 , A61B5/150358 , A61B5/150969 , A61B10/0045 , A61B2010/008
摘要： Systems and methods use extraction devices for extracting and monitoring biological fluids of patients. The systems and methods involve creating an opening in the biological tissue of the patient and placing a sampling aperture of the extraction device over the opening. The sampling aperture is defined in a contact surface of the extraction device that is placed into contact with the tissue of the patient. A pump of the extraction device such as a depressible bulb sealed to the body is charged to create a vacuum between the pump through a sampling channel to the sampling aperture, and the vacuum draws the biological fluid from the tissue opening into the sampling channel. An access point is exposed to the sampling channel, and the sample of fluid may be accessed from the access point. The access point may be an extraction opening covered by an access door, and the access door is opened to access the sample. Alternatively, the access point may be electrodes extending into the sampling channel where the electrodes are connectable to a fluid analyzer device.

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