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    • 2. 发明申请
    • RADIOACTIVE-EMISSION-MEASUREMENT OPTIMIZATION TO SPECIFIC BODY STRUCTURES
    • 放射性排放测量优化到特定体系结构
    • WO2005119025A3
    • 2007-07-05
    • PCT/IL2005000575
    • 2005-06-01
    • SPECTRUM DYNAMICS LLCNAGLER MICHAELDICHTERMAN ELIZILBERSTEIN YOELRAVHON RANZIV OMERROUSSO BENNYBEN-HAIM SHLOMO
    • NAGLER MICHAELDICHTERMAN ELIZILBERSTEIN YOELRAVHON RANZIV OMERROUSSO BENNYBEN-HAIM SHLOMO
    • G06K9/00C08F210/00F02B1/00G01T1/164
    • A61B6/481A61B6/00A61B6/02A61B6/06A61B6/4258A61B6/4266A61B6/54G01T1/1642G01T1/1644G06T7/0012G06T2207/10072
    • Systems, methods, and probes are provided for functional imaging by radioactive-emission-measurements, specfic to body structures, such as the prostate, the esophagus, the cervix, the uterus, the ovaries, the heart, the breast, the brain, and the whole body, and other body structures (fig. 5c element 206). The nuclear imaging may be performed alone, or together with structural imaging, for example, by x-rays, ultrasound, or MRI. Preferably, the radioactive-emission-measuring probes include detectors, which are adapted for individual motions with respect to the probe housings, to generate views from different orientations and to change their view orientations (fig. 5c element 207). These motions are optimized with respect to functional information gained about the body structure, by identifying preferred sets of views for measurements, based on models of the body structures abd information theoretic measures (fig. 5c element 208). A second iteration, for identifying preferred sets of views for measurements of a portion of body structure, based on models of a location of a pathology that has been identified, makes it possible, in effect, to zoom in on a suspected pathology. The systems are programmed to provide these motions automatically.
    • 提供了系统,方法和探针,用于通过放射性发射测量进行功能成像,特异性的身体结构,例如前列腺,食管,子宫颈,子宫,卵巢,心脏,乳房,大脑和 全身和其他身体结构(图5c元件206)。 核成像可以单独进行,或者与结构成像一起进行,例如通过X射线,超声或MRI进行。 优选地,放射性发射测量探针包括适于相对于探针壳体的单独运动的检测器,以从不同取向产生视图并改变其视点取向(图5c元件207)。 通过基于身体结构abd信息理论测量的模型(图5c元件208),通过识别用于测量的优选视图集合,关于关于身体结构获得的功能信息优化这些运动。 基于已经识别的病理学位置的模型,第二次迭代用于识别用于体部结构的一部分的测量的优选视图组,使得实际上可以放大可疑的病理学。 系统被编程为自动提供这些运动。
    • 4. 发明申请
    • RECONSTRUCTION STABILIZER AND ACTIVE VISION
    • 重建稳定器和主动愿景
    • WO2007010537A2
    • 2007-01-25
    • PCT/IL2006000840
    • 2006-07-19
    • SPECTRUM DYNAMICS LLCROUSSO BENNYDICHTERMAN ELIZIV OMERBEN-HAIM SHLOMO
    • ROUSSO BENNYDICHTERMAN ELIZIV OMERBEN-HAIM SHLOMO
    • G06T5/10
    • A61K51/02A61B5/02755A61B5/06A61B5/415A61B5/418A61K51/04A61K51/0402A61K51/0476A61K51/0478A61K51/048A61K51/0489A61K51/0491A61K51/1203
    • A method for stabilizing the reconstruction of an imaged volume is presented. The method includes the steps of performing an analysis of the reliability of reconstruction of a radioactive-emission density distribution of the volume from radiation detected over a specified set of views, and defining modifications to the reconstruction process and/or data collection process to improve the reliability of reconstruction, in accordance with the analysis. Additionally, a method is described for performing radioactive-emission measurements of a body structure. The method is dynamically defining further views for measurements, based on an analysis measurements results obtained during the current emission measurement procedure. The definition of the further views is performed without terminating the current measurement process. The preferred sets of views may then be applied immediately to the body structure. The method may be performed iteratively, to zoom in on a region of interest. The dynamically-defined views may be provided as the modifications defined by the method to improve the reliability of reconstruction.
    • 呈现稳定成像体重建的方法。 该方法包括以下步骤:对在特定视图中检测到的放射线对体积的放射性发射密度分布进行重建的可靠性进行分析,并且对重建过程和/或数据收集过程进行修改以改进 可靠性重建,按照分析。 另外,描述了一种用于进行身体结构的放射性发射测量的方法。 该方法基于在当前排放测量程序期间获得的分析测量结果动态地定义测量的进一步视图。 在不终止当前测量过程的情况下执行进一步视图的定义。 然后可以将优选的视图集合立即应用于身体结构。 可以迭代地执行该方法,以放大感兴趣的区域。 可以提供动态定义的视图作为由该方法定义的改进以提高重建的可靠性。
    • 5. 发明申请
    • DYNAMIC SPECT CAMERA
    • 动态SPECT摄像机
    • WO2007054935A3
    • 2007-11-22
    • PCT/IL2006001291
    • 2006-11-09
    • SPECTRUM DYNAMICS LLCROUSSO BENNYZIV OMERNAGLER MICHAELBEN-HAIM SHLOMO
    • ROUSSO BENNYZIV OMERNAGLER MICHAELBEN-HAIM SHLOMO
    • G01T1/161G01T1/166G01T1/29
    • G01T1/161A61B6/037G01T1/166G01T1/2985
    • A dynamic SPECT camera is provided, comprising, a plurality of single-pixel detectors, a timing mechanism, in communication with each single-pixel detector, configured for enabling time-binning of the radioactive emissions impinging upon each single-pixel detector to time periods not greater than substantially 30 seconds, and a position-tracker, configured for providing information on the position and orientation of each detecting unit, with respect to the overall structure, substantially at all times, during the individual motion, the dynamic SPECT camera being configured for acquiring a tomographic reconstruction image of a region of interest of about 15 X 15 X 15 cubic centimeters, during an acquisition time of 30 seconds, at a spatial resolution of at least 10 X 10 X 10 cubic millimeter. The dynamic camera is configured for very short damping time, and may further acquire images in a stationary mode, with no motion. It is further configured for time binning at dynamically varying time-bin lengths,dynamically determining a spectral energy bin for each detecting unit, and employing an anatomic construction of voxels in the imaging and reconstruction.
    • 提供动态SPECT照相机,其包括多个单像素检测器以及与每个单像素检测器通信的定时机构,该定时机构被配置为使得撞击在每个单像素检测器上的放射性发射的时间组合到时间段 不大于大致30秒;以及位置跟踪器,其被配置用于在个体运动期间基本上在所有时间相对于整体结构提供关于每个检测单元的位置和方向的信息,动态SPECT相机被配置 用于在30秒的采集时间期间以至少10 X 10 X 10立方毫米的空间分辨率获取约15 X 15 X 15立方厘米的感兴趣区域的层析X射线重建图像。 动态摄像机配置的阻尼时间非常短,并且可以进一步采用静止模式获取图像,而无需移动。 它还被配置用于在动态变化的时间段长度上进行时间分级,动态地确定每个检测单元的频谱能量仓,并且在成像和重建中采用体素的解剖结构。