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1. 发明申请

WO2014131160A1 MULTI-CHANNEL OPTICAL TRANSMITTER ASSEMBLY AND METHODS OF MAKING AND USING THE SAME 审中-公开
标题翻译：多通道光学发射器组件及其制造和使用方法
公开(公告)号：WO2014131160A1
公开(公告)日：2014-09-04
申请号：PCT/CN2013/071928
申请日：2013-02-27
申请人： SOURCE PHOTONICS (CHENGDU) CO., LTD. , ZHANG, Sheng , MARGALIT, Near , HEIMBUCH, Mark
发明人： ZHANG, Sheng , MARGALIT, Near , HEIMBUCH, Mark
IPC分类号： H04J14/02 , G02B27/28
CPC分类号： H04J14/06 , G02B5/3083 , G02B27/141 , G02B27/28 , G02B27/283 , G02F1/093 , H04B10/40 , H04B10/503 , H04J14/02
摘要： An optical multiplexer and methods of making and using the same are disclosed. The multiplexer generally includes a beam splitter and a polarization beam splitter. The beam splitter is generally configured to combine first and second polarized optical signals by reflecting a first polarized optical signal towards a first target and allowing a second polarized optical signal to pass through towards the first target. The polarization beam splitter is generally configured to combine the first and second polarized optical signals with a third polarized optical signal by either (i) reflecting the third polarized optical signal towards a second target and allowing the first and second polarized optical signals to pass through towards the second target, or (ii) reflecting the first and second polarized optical signals towards the second target and allowing the third polarized optical signal to pass through towards the second target.
摘要翻译：公开了一种光复用器及其制作和使用方法。复用器通常包括分束器和偏振分束器。分束器通常被配置为通过向第一目标反射第一偏振光信号并允许第二偏振光信号朝向第一目标通过来组合第一和第二偏振光信号。偏振分束器通常被配置为通过以下方式（i）将第三偏振光信号反射向第二目标并使第一和第二偏振光信号通过朝向第二目标，或者（ii）朝向第二目标反射第一和第二偏振光信号，并允许第三偏振光信号朝向第二目标通过。

2. 发明公开

EP2773566A2 APPLICATORS FOR STORING, STERILIZING, AND DISPENSING AN ADHESIVE 审中-公开
标题翻译：涂抹储存，灭菌和拘留问题所作
公开(公告)号：EP2773566A2
公开(公告)日：2014-09-10
申请号：EP12846036.7
申请日：2012-11-01
申请人： Adhezion Biomedical, LLC , Ruiz, Rafael, Sr. , Zhang, Sheng , Krauss, Martin
发明人： RUIZ, Rafael, Sr. , ZHANG, Sheng , KRAUSS, Martin
IPC分类号： B65D25/40
CPC分类号： A61B17/00491 , A46B11/0075 , A61B2090/0813 , A61M35/003 , A61M35/006 , B05C17/00586 , B65D35/36 , B65D51/225
摘要： Applicators for storing, sterilizing, and dispensing adhesives. The applicators comprise a porous tip, a body, and a container containing a polymerizable cyanoacrylate monomer adhesive. The applicators are sterilized by radiation, and following sterilization, the adhesive remains substantially unpolymerized for about twenty four months.

3. 发明申请

WO2014172519A1 PACKAGE SYSTEM FOR STERILIZING AND STORING CYANOACRYLATE ADHESIVE COMPOSITIONS 审中-公开
标题翻译：用于灭菌和储存氰基丙烯酸酯胶粘剂组合物的包装系统
公开(公告)号：WO2014172519A1
公开(公告)日：2014-10-23
申请号：PCT/US2014/034449
申请日：2014-04-17
申请人： ADHEZION BIOMEDICAL, LLC , ZHANG, Sheng , RUIZ, Rafael, Sr.
发明人： ZHANG, Sheng , RUIZ, Rafael, Sr.
IPC分类号： A61L2/08 , A61L2/20 , A61L2/00 , B65B55/16
CPC分类号： A61J1/067 , A61L2/0029 , A61L2/08 , A61L2/206
摘要： Package systems that provide for prolonged shelf stability of sterilized cyanoacrylate compositions are provided. The package systems include an ampoule made from a material that is substantially impervious to gas and moisture penetration that includes a frangible foil seal, and an overpack. The ampoule contains a stabilized cyanoacrylate monomer composition, and may be sterilized by irradiation without substantially altering the viscosity of the composition. The package may be sterilized by ethylene oxide without substantially further altering the viscosity of the composition. The sterilized composition, when contained within the package system, is shelf-stable for a period of at least 24 months.
摘要翻译：提供了提供灭菌的氰基丙烯酸酯组合物的长期贮存稳定性的包装系统。包装系统包括由基本上不透气体和水分渗透的材料制成的安瓿，其包括易碎箔密封件和外包装。安瓿含有稳定的氰基丙烯酸酯单体组合物，并且可以通过辐射灭菌而基本上不改变组合物的粘度。包装可以被环氧乙烷灭菌，而基本上不会进一步改变组合物的粘度。灭菌的组合物当包装在包装系统内时，是至少24个月的货架稳定的。

4. 发明申请

WO2013067127A2 APPLICATORS FOR STORING, STERILIZING, AND DISPENSING AN ADHESIVE 审中-公开
标题翻译：用于储存，灭菌和分配粘合剂的施加者
公开(公告)号：WO2013067127A2
公开(公告)日：2013-05-10
申请号：PCT/US2012/062976
申请日：2012-11-01
申请人： ADHEZION BIOMEDICAL, LLC , RUIZ, Rafael, Sr. , ZHANG, Sheng , KRAUSS, Martin
发明人： RUIZ, Rafael, Sr. , ZHANG, Sheng , KRAUSS, Martin
IPC分类号： B65D25/40
CPC分类号： A61B17/00491 , A46B11/0075 , A61B2090/0813 , A61M35/003 , A61M35/006 , B05C17/00586 , B65D35/36 , B65D51/225
摘要： Applicators for storing, sterilizing, and dispensing adhesives are provided. The applicators comprise a porous tip, a body, and a container containing a polymerizable cyanoacrylate monomer adhesive. The applicators are sterilized by radiation, and following sterilization, the adhesive remains substantially unpolymerized for about twenty four months.
摘要翻译：提供了用于存储，消毒和分散粘合剂的涂布器。施用器包括多孔尖端，主体和容纳可聚合的氰基丙烯酸酯单体粘合剂的容器。施用器通过辐射灭菌，并且在灭菌后，粘合剂基本上未聚合约二十四个月。

5. 发明申请

WO2012021521A1 WOUND HEALING COMPOSITIONS BASED ON CYANOACRYLATES AND 5,5-DISUBSTITUTEDHYDANTOINS, INCLUDING PHENYTOIN 审中-公开
标题翻译：基于氰基丙烯酸酯和5,5-DISUBSTITUTEDHYDANTOINS的包裹苯并噻唑的组合物
公开(公告)号：WO2012021521A1
公开(公告)日：2012-02-16
申请号：PCT/US2011/047090
申请日：2011-08-09
申请人： ADHEZION BIOMEDICAL, LLC , ZHANG, Sheng , RUIZ, Rafael, Sr.
发明人： ZHANG, Sheng , RUIZ, Rafael, Sr.
IPC分类号： C08K5/05
CPC分类号： A61L26/0066 , A61K31/4166 , A61K31/785 , A61L24/0015 , A61L24/0021 , A61L24/02 , A61L24/06 , A61L26/0004 , A61L26/0014 , A61L26/0071 , A61L2300/404 , A61L2300/412 , C08F22/32 , C08L35/04
摘要： A monomeric adhesive composition includes a stabilized polymerizable monomer, such as a 1, 1 -disubstituted monomer, including a cyanoacrylate, and a wound healing agent, wherein the wound healing agent is 5,5-disubstitutedhydantoin, including phenytoin; and a method for making said composition.
摘要翻译：单体粘合剂组合物包括稳定的可聚合单体，例如包括氰基丙烯酸酯的1,1-取代单体和伤口愈合剂，其中伤口愈合剂是5,5-二取代的乙内酰脲，包括苯妥英; 和制备所述组合物的方法。

6. 发明申请

WO2012040031A1 APPLICATORS FOR DISPENSING ADHESIVE OR SEALANT MATERIAL 审中-公开
标题翻译：用于调配粘合剂或密封材料的应用者
公开(公告)号：WO2012040031A1
公开(公告)日：2012-03-29
申请号：PCT/US2011/051762
申请日：2011-09-15
申请人： ADHEZION BIOMEDICAL, LLC , RUIZ, Rafael, Sr. , ZHANG, Sheng , KRAUSS, Martin
发明人： RUIZ, Rafael, Sr. , ZHANG, Sheng , KRAUSS, Martin
IPC分类号： A61B17/00
CPC分类号： A61B17/00491
摘要： An applicator device (180) for storing and dispensing an adhesive or sealant material, which are compatible with irradiation sterilization techniques, the applicator comprising: an applicator body (130) comprising a cutting portion (104) to break a frangible seal (108) of a container (120) for the adhesive, and a grasping and squeezing portion (118) for controlling the flow rate of the adhesive; the container for the adhesive material that is movable relative to the applicator body and is made of materials with high barrier property; and a porous applicator tip (110) that is secured to or frictionally fits into the applicator body.
摘要翻译：一种用于储存和分配粘合剂或密封剂材料的涂抹器装置（180），其与辐射灭菌技术相容，所述涂抹器包括：施加器主体（130），包括切割部分（104），以将破裂密封件（108）用于粘合剂的容器（120）以及用于控制粘合剂流速的把持和挤压部分（118）用于粘合剂材料的容器，其相对于涂抹器主体可移动并且由具有高阻隔性的材料制成; 以及固定到摩擦配合到施用器主体中的多孔施用器尖端（110）。

7. 发明申请

WO2010118241A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES 审中-公开
标题翻译：蛋白酪氨酸磷酸酶抑制剂
公开(公告)号：WO2010118241A2
公开(公告)日：2010-10-14
申请号：PCT/US2010/030409
申请日：2010-04-08
申请人： INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION , ZHANG, Zhong-yin , ZHANG, Sheng
发明人： ZHANG, Zhong-yin , ZHANG, Sheng
IPC分类号： A61K38/06
CPC分类号： C07K5/0812 , A61K38/00 , C07K5/06078 , C12Q1/42 , G01N33/505 , G01N2333/916
摘要： Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC- PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.
摘要翻译：本文公开了选择性抑制PTP家族成员的化合物。合成化合物显示TC-PTP的选择性抑制。还提供了使用含有化合物的化合物和制剂的方法。还描述了荧光标记的组合文库合成和筛选方法。以及使用这些化合物在细胞和体外都能够影响酶活性的方法以及使用这些化合物治疗人和动物疾病的方法。

8. 发明申请

WO2010008822A3 CYANOACRYLATE TISSUE ADHESIVES WITH DESIRABLE PERMEABILITY AND TENSILE STRENGTH 审中-公开
公开(公告)号：WO2010008822A3
公开(公告)日：2010-01-21
申请号：PCT/US2009/048234
申请日：2009-06-23
申请人： ADHEZION BIOMEDICAL, LLC , ZHANG, Sheng , RUIZ, Rafael
发明人： ZHANG, Sheng , RUIZ, Rafael
IPC分类号： A61L24/06 , C09J4/00
摘要： A sterilized cyanoacrylate adhesive composition including a cyanoacrylate composition and a cure speed enhancer, wherein said sterilized cyanoacrylate adhesive composition does not cure upon sterilization, and wherein the composition when cured to form a film on a patient's tissue has water vapor transmission rate from about 950 to about 3000g/m 2 /day.

9. 发明申请

WO2009003017A1 CURING ACCELERATOR AND METHOD OF MAKING 审中-公开
标题翻译：固化加速器和制造方法
公开(公告)号：WO2009003017A1
公开(公告)日：2008-12-31
申请号：PCT/US2008/068152
申请日：2008-06-25
申请人： ADHEZION BIOMEDICAL , ZHANG, Sheng
发明人： ZHANG, Sheng
IPC分类号： A61K31/74 , B32B5/02
CPC分类号： A61L24/06 , A61L24/0015 , A61L26/0014 , A61L26/0066 , A61L2300/602 , A61L2300/624 , C08L35/06
摘要： A sterilized cyanoacrylate adhesive composition including a cyanoacrylate composition and a cure speed enhancer, wherein the sterilized cyanoacrylate adhesive composition does not cure upon sterilization. A kit for applying the sterilized cyanoacrylate adhesive composition, including the cyanoacrylate adhesive composition and an applicator. A method of making the sterilized cyanoacrylate adhesive composition, by adding a cure speed enhancer to a cyanoacrylate adhesive composition and sterilizing the composition. A method of applying the sterilized cyanoacrylate adhesive composition to tissue by applying the sterilized cyanoacrylate adhesive composition as a liquid, and quickly curing the sterilized cyanoacrylate adhesive composition. A method of sealing tissue by applying the sterilized cyanoacrylate adhesive composition as a liquid to tissue to be sealed, quickly curing the sterilized cyanoacrylate adhesive composition, and sealing the tissue.
摘要翻译：一种灭菌的氰基丙烯酸酯粘合剂组合物，其包含氰基丙烯酸酯组合物和固化速度增强剂，其中灭菌的氰基丙烯酸酯粘合剂组合物在灭菌时不固化。一种用于施用灭菌的氰基丙烯酸酯粘合剂组合物的试剂盒，包括氰基丙烯酸酯粘合剂组合物和涂布器。通过向氰基丙烯酸酯粘合剂组合物中加入固化速度增强剂并对组合物进行灭菌来制备灭菌的氰基丙烯酸酯粘合剂组合物的方法。通过将灭菌的氰基丙烯酸酯粘合剂组合物作为液体施用灭菌的氰基丙烯酸酯粘合剂组合物并快速固化灭菌的氰基丙烯酸酯粘合剂组合物的方法。通过将灭菌的氰基丙烯酸酯粘合剂组合物作为液体施加到待密封的组织上，快速固化灭菌的氰基丙烯酸酯粘合剂组合物并密封组织来密封组织的方法。

10. 发明申请

WO2019060213A1 OLED VOLTAGE DRIVER WITH CURRENT-VOLTAGE COMPENSATION 审中-公开
公开(公告)号：WO2019060213A1
公开(公告)日：2019-03-28
申请号：PCT/US2018/051023
申请日：2018-09-14
申请人： APPLE INC. , ZHANG, Sheng , LE, Chengrui , BAE, Hopil , BAROUGHI, Mahdi Farrokh , LUM, David W. , ADJIWIBAWA, Adam , WANG, Chaohao , SACCHETTO, Paolo , YAO, Wei H. , DORJGOTOV, Enkhamgalan , SLOOTSKY, Michael , CARBONE, Giovanni , SHAEFFER, Derek K. , JEN, Henry C. , HATANAKA, Shingo , AKYOL, Hasan
发明人： ZHANG, Sheng , LE, Chengrui , BAE, Hopil , BAROUGHI, Mahdi Farrokh , LUM, David W. , ADJIWIBAWA, Adam , WANG, Chaohao , SACCHETTO, Paolo , YAO, Wei H. , DORJGOTOV, Enkhamgalan , SLOOTSKY, Michael , CARBONE, Giovanni , SHAEFFER, Derek K. , JEN, Henry C. , HATANAKA, Shingo , AKYOL, Hasan
IPC分类号： G09G3/3208 , G09G3/3233
摘要： An electronic device includes a display having a reference array that includes a first pixel. The display also includes a first emission power supply coupled to the first pixel. The display further includes an active array having a second pixel. The display also includes a second emission power supply coupled to the second pixel.

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