专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2004018478A3 SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO, ANALOGUES AND USES THEREOF 审中-公开
标题翻译：爱宕素的合成，中间体，类似物及其用途
公开(公告)号：WO2004018478A3
公开(公告)日：2004-12-09
申请号：PCT/US0326367
申请日：2003-08-22
申请人： SLOAN KETTERING INST CANCER , DANISHEFSKY SAMUEL J , RIVKIN ALEXEY , YOSHIMURA FUMIHIKO , GABARDA ORTEGA ANA ESTHER , CHO YOUNG SHIN , CHOU TING-CHAO , DONGM HUAJIN
发明人： DANISHEFSKY SAMUEL J , RIVKIN ALEXEY , YOSHIMURA FUMIHIKO , GABARDA ORTEGA ANA ESTHER , CHO YOUNG SHIN , CHOU TING-CHAO , DONGM HUAJIN
IPC分类号： C07D417/06 , C07D493/04 , C07D419/06 , A61K31/425 , C07D303/00 , C07D313/00 , C07D413/06
CPC分类号： C07D417/06 , C07D493/04
摘要： The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).
摘要翻译：本发明提供了式（I）的化合物：如通常和本文的类别和亚类中所述。本发明另外提供了包含式（I）化合物的药物组合物并且提供了治疗癌症的方法，其包括施用式（I）化合物。

2. 发明申请

WO2005084222A3 SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO, ANALOGUES AND USES THEREOF 审中-公开
公开(公告)号：WO2005084222A3
公开(公告)日：2005-11-24
申请号：PCT/US2005006051
申请日：2005-02-28
申请人： SLOAN KETTERING INST CANCER , DANISHEFSKY SAMUEL J , RIVKIN ALEXEY , YOSHIMURA FUMIHIKO , CHOU TING-CHAO , GABARDA ORTEGA ANA ESTHER , DONG HUAJIN , WU KAIDA , MOORE MALCOLM A S , DORN DAVID
发明人： DANISHEFSKY SAMUEL J , RIVKIN ALEXEY , YOSHIMURA FUMIHIKO , CHOU TING-CHAO , GABARDA ORTEGA ANA ESTHER , DONG HUAJIN , WU KAIDA , MOORE MALCOLM A S , DORN DAVID
IPC分类号： A61K31/426 , C07D277/20 , C07D417/06 , C07D493/04
CPC分类号： C07D417/06 , C07D413/06 , C07D493/04
摘要： The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).

3. 发明公开

EP1722791A4 SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO, ANALOGUES AND USES THEREOF 审中-公开
标题翻译：埃博霉素的合成，中间物，类似物及其用途
公开(公告)号：EP1722791A4
公开(公告)日：2010-06-09
申请号：EP05723768
申请日：2005-02-28
申请人： SLOAN KETTERING INST CANCER
发明人： DANISHEFSKY SAMUEL J , RIVKIN ALEXEY , YOSHIMURA FUMIHIKO , CHOU TING-CHAO , GABARDA ORTEGA ANA ESTHER , DONG HUAJIN , WU KAIDA , MOORE MALCOLM A S , DORN DAVID
IPC分类号： A61K31/426 , A61P35/00 , C07D277/20 , C07D413/06 , C07D417/06 , C07D493/04
CPC分类号： C07D417/06 , C07D413/06 , C07D493/04

4. 发明专利

AU2011202835A1 Synthesis of epothilones, intermediates thereto, analogues and uses thereof 未知
公开(公告)号：AU2011202835A1
公开(公告)日：2011-07-07
申请号：AU2011202835
申请日：2011-06-14
申请人： SLOAN KETTERING INST CANCER RES
发明人： DANISHEFSKY SAMUEL J , RIVKIN ALEXEY , YOSHIMURA FUMIHIKO , CHOU TING-CHAO , GABARDA ORTEGA ANA ESTHER , DONG HUAJIN , WU KAIDA , MOORE MALCOLM A S , DORN DAVID
IPC分类号： C07D277/20 , A61K31/426 , A61P35/00
摘要： The present invention provides compounds of formula (1): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (1) and provides methods of treating cancer comprising administering a compound of formula (1).

5. 发明专利

DE60310916D1 未知
公开(公告)号：DE60310916D1
公开(公告)日：2007-02-15
申请号：DE60310916
申请日：2003-08-22
申请人： SLOAN KETTERING INST CANCER
发明人： DANISHEFSKY J , RIVKIN ALEXEY , YOSHIMURA FUMIHIKO , GABARDA ORTEGA ANA ESTHER , CHO SHIN , CHOU TING-CHAO , DONG HUAJIN
IPC分类号： C07D493/00 , C07D417/06 , C07D493/04
摘要： The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).

6. 发明专利

AU2005218308A1 Synthesis of epothilones, intermediates thereto, analogues and uses thereof 未知
公开(公告)号：AU2005218308A1
公开(公告)日：2005-09-15
申请号：AU2005218308
申请日：2005-02-28
申请人： SLOAN KETTERING INST CANCER RES
发明人： MOORE MALCOLM A S , ORTEGA ANA ESTHER GABARDA , DONG HUAJIN , CHOU TING-CHAO , RIVKIN ALEXEY , DORN DAVID , WU KAIDA , YOSHIMURA FUMIHIKO , DANISHEFSKY SAMUEL J
IPC分类号： A61K31/426 , C07D277/20 , C07D417/06 , C07D493/04
摘要： The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).

7. 发明专利

AU2003260002B2 Synthesis of epothilones, intermediates thereto, analogues and uses thereof 未知
公开(公告)号：AU2003260002B2
公开(公告)日：2010-03-18
申请号：AU2003260002
申请日：2003-08-22
申请人： SLOAN KETTERING INST CANCER RES
发明人： YOSHIMURA FUMIHIKO , ORTEGA ANA ESTHER GABARDA , CHOU TING-CHAO , RIVKIN ALEXEY , DANISHEFSKY SAMUEL J , DONGM HUAJIN , CHO YOUNG SHIN
IPC分类号： C07D417/06 , C07D493/04
摘要： The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).

8. 发明专利

CA2496477A1 SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO, ANALOGUES AND USES THEREOF 未知
公开(公告)号：CA2496477A1
公开(公告)日：2004-03-04
申请号：CA2496477
申请日：2003-08-22
申请人： SLOAN KETTERING INST CANCER
发明人： YOSHIMURA FUMIHIKO , RIVKIN ALEXEY , DANISHEFSKY SAMUEL J , CHO YOUNG SHIN , CHOU TING-CHAO , GABARDA ORTEGA ANA ESTHER , DONG HUAJIN
IPC分类号： C07D417/06 , C07D493/04 , C07D419/06 , C07D277/00 , C07D303/00 , C07D313/00 , C07D413/06 , A61K31/425
摘要： The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).

9. 发明专利

CA2496477C SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO, ANALOGUES AND USES THEREOF 未知
公开(公告)号：CA2496477C
公开(公告)日：2012-10-16
申请号：CA2496477
申请日：2003-08-22
申请人： SLOAN KETTERING INST CANCER
发明人： DANISHEFSKY SAMUEL J , RIVKIN ALEXEY , YOSHIMURA FUMIHIKO , GABARDA ORTEGA ANA ESTHER , CHO YOUNG SHIN , CHOU TING-CHAO , DONG HUAJIN
IPC分类号： C07D419/06 , A61K31/425 , C07D277/00 , C07D303/00 , C07D313/00 , C07D413/06 , C07D417/06 , C07D493/04
摘要： The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).

10. 发明专利

ES2336937T3 SINTESIS DE EPOTILONAS, SUS INTERMEDIOS, ANALOGOS Y USOS. 未知
公开(公告)号：ES2336937T3
公开(公告)日：2010-04-19
申请号：ES06026750
申请日：2003-08-22
申请人： SLOAN KETTERING INST CANCER
发明人： DANISHEFSKY SAMUEL J , RIVKIN ALEXEY , YOSHIMURA FUMIHIKO , GABARDA ORTEGA ANA ESTHER , CHO YOUNG SHIN , CHOU TING-CHAO
IPC分类号： C07D419/06 , A61K31/425 , C07D277/00 , C07D303/00 , C07D313/00 , C07D413/06 , C07D417/06 , C07D493/04
摘要： Un procedimiento para preparar un compuesto de fórmula: **(Ver fórmula)** en la que R1 es hidrógeno o alquilo inferior C1-6; R2 es un resto arilo C3-14, heteroarilo C3-14, aril C3-14-alquilo C1-20 o heteroaril C3-14-alquilo C1-20 sustituido o sin sustituir; cada uno de R5 y R6 es independientemente hidrógeno o un grupo protector; X es O, S, C(R7)2 o NR7, donde cada vez que aparece R7 es independientemente hidrógeno o alquilo inferior C1-6; RB es, independientemente en cada caso, hidrógeno; halógeno; -ORB''; -SRB''; -N(RB'')2; -CY3, -CHY2, -CH2Y, donde Y es F, Br, Cl, I, ORB'', NHRB'', N(RB'')2 o SRB''; -C(O)ORB''; -C(O)R B''; -CON-HRB''; -O(C=O)RB''; -O(C=O) ORB''; -NRB''(C=O)RB''; N3; N2R B''; acetal cíclico; o arilo C3-14 o heteroarilo C3-14 alifático C1-20, heteroalifático C1-20 cíclico o acíclico, lineal o ramificado, opcionalmente sustituido con uno o más de hidrógeno; halógeno; -ORB''; -SRB''; -N(RB'')2; -C(O)ORB''; -C(O)R B''; -CONHRB''; -O(C=O)RB''; -O(C-O)ORB''; -NRB''(C=O)RB''; N3; N2RB''; acetal cíclico; o un resto arilo C3-14 o heteroarilo C3-14 alifático C1-20, heteroalifáctico C1-20 cíclico o acíclico, lineal o ramificado sustituido o sin sustituir; o es una epotilona, desoxiepotilona o análogos de las mismas; o es un polimero; carbohidrato; marcador de fotoafinidad; o radiomarcador; donde cada vez que aparece RB'' es independientemente hidrógeno; un grupo protector; C1-20 alifático, hetero C1-20 alifático, un resto arilo C3-14, heteroarilo C3-14, aril C3-14-alquilo C1-20, aril C3-14-alquenilo C1-20, aril C3-14-alquinilo C1-20, heteroaril C3-14-alquilo C1-20, heteroaril C3-14-alquenilo C1-20 o heteroaril C3-14-alquinilo C1-20 alifático C1-20, heteroalifático C1-20 cíclico o acíclico; y m es 1, 2, 3 ó 4, comprendiendo el procedimiento las etapas de: someter un compuesto de la fórmula: **(Ver fórmula)** a condiciones de una reacción de metátesis con cierre de anillo.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式