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1. 发明申请

WO2018129169A1 MAGNETIC BIOSENSOR DESIGN FOR MANUFACTURING 审中-公开
公开(公告)号：WO2018129169A1
公开(公告)日：2018-07-12
申请号：PCT/US2018/012357
申请日：2018-01-04
申请人： SILICON BIODEVICES, INC.
发明人： IZYUMIN, Igor , FLORESCU, Octavian
IPC分类号： G01N27/74 , G01N27/72 , G01N33/53 , H01R12/72 , H01R12/70 , H05K1/02 , H05K1/14
摘要： A stand-alone assay system for POC IVD that is fast, easy to use, inexpensive and delivers laboratory quality results for one or more target analytes from a small volume of unprocessed aqueous sample is disclosed. The stand-alone assay system is a disposable digital device. The stand-alone assay system integrates a sampling system that relies on users swiping a lanced finger containing an unprocessed aqueous sample such as whole blood across a sample inlet to transfer or deposit the unprocessed aqueous sample on to a membrane filter or into a capillary. The system can have a planarized testing surface on which retained magnetic particles are sensed.

2. 发明申请

WO2011059512A1 FILTRATION DEVICE FOR ASSAYS 审中-公开
标题翻译：用于测定的过滤装置
公开(公告)号：WO2011059512A1
公开(公告)日：2011-05-19
申请号：PCT/US2010/002994
申请日：2010-11-16
申请人： SILICON BIODEVICES, INC. , FLORESCU, Octavian
发明人： FLORESCU, Octavian
IPC分类号： G01N33/553
CPC分类号： G01N33/54333 , B01L3/502753 , B01L2200/0647 , B01L2200/12 , B01L2300/0636 , B01L2300/0681 , B01L2300/0874 , B01L2400/043 , G01N33/54326 , G01N33/54386 , G01N2458/00 , Y10T137/8013 , Y10T436/25375
摘要： A device and method for filtering blood is disclosed herein. The device can filter blood and attach analytes within the blood to magnetic particles. The analytes can then be strongly bound to an analyzing device by a magnetic force. The analytes can then be counted by the analyzing device and the result can be displayed.
摘要翻译：本文公开了一种用于过滤血液的装置和方法。该装置可以过滤血液并将血液内的分析物附着到磁性颗粒上。然后，分析物可以通过磁力强烈地结合到分析装置。然后可以通过分析装置对分析物进行计数，并且可以显示结果。

3. 发明申请

WO2014189624A1 DIGITAL CONTROL OF ON-CHIP MAGNETIC PARTICLE ASSAY 审中-公开
标题翻译：片上磁性粒子测定数字控制
公开(公告)号：WO2014189624A1
公开(公告)日：2014-11-27
申请号：PCT/US2014/033607
申请日：2014-04-10
申请人： SILICON BIODEVICES, INC.
发明人： FLORESCU, Octavian , WONG, Daniel , MARTIN, Tracie , YAMASAKI, Duane , CROMER, Remy
IPC分类号： G01N21/82
CPC分类号： G01N33/54326 , B01L3/502761 , B01L3/561 , B01L2200/0605 , B01L2200/0668 , B01L2200/148 , B01L2200/16 , B01L2300/023 , B01L2300/027 , B01L2300/0636 , B01L2300/0838 , B01L2300/0874 , B01L2300/12 , B01L2400/0406 , B01L2400/043 , C12Q1/686 , G01N21/255 , G01N21/82 , G01N27/745 , G01N2201/061 , G01N2201/068 , G06F21/602 , G06K19/06028 , G06K19/06037 , G16H50/20 , Y02A90/26
摘要： An assay system and method for use in the field of chemical testing is disclosed. The assay system can be used for filtering whole blood for testing on an integrated circuit containing digital control functionality.
摘要翻译：公开了用于化学测试领域的测定系统和方法。该测定系统可用于过滤全血以在包含数字控制功能的集成电路上进行测试。

4. 发明申请

WO2012048288A1 MAGNETIC PARTICLE BASED BIOSENSOR 审中-公开
标题翻译：基于磁性颗粒的生物传感器
公开(公告)号：WO2012048288A1
公开(公告)日：2012-04-12
申请号：PCT/US2011/055467
申请日：2011-10-07
申请人： SILICON BIODEVICES, INC. , FLORESCU, Octavian
发明人： FLORESCU, Octavian
IPC分类号： G01N21/00
CPC分类号： G01N33/54366 , G01N15/1436 , G01N21/17 , G01N21/253 , G01N21/274 , G01N21/78 , G01N33/54326 , G01N2201/062 , G01V8/20
摘要： A biosensor system and method of its use for detecting particles on the surface of an integrated circuit is disclosed. The system can include a light source and a plurality of optical sensors formed on an integrated circuit. The particles can be positioned the surface of the integrated circuit whereby the particles can cast a shadow or shadows that reduces the amount of light transmitted from the light source to the optical sensors. The surface of the integrated circuit can include one or more optical sensing areas whereby the presence of one or more particles may significantly or measurably reduce the amount of light incident on one or more optical sensor.
摘要翻译：公开了一种用于检测集成电路表面上的颗粒的生物传感器系统及其方法。该系统可以包括形成在集成电路上的光源和多个光学传感器。颗粒可以定位在集成电路的表面上，由此颗粒可以投射阴影或阴影，从而将从光源传输的光量减少到光学传感器。集成电路的表面可以包括一个或多个光学感测区域，由此一个或多个颗粒的存在可以显着或可测量地减少入射在一个或多个光学传感器上的光量。

5. 发明申请

WO2017062991A1 INDUSTRIAL DESIGN OF STAND-ALONE ASSAY SYSTEM 审中-公开
标题翻译：独立测试系统的工业设计
公开(公告)号：WO2017062991A1
公开(公告)日：2017-04-13
申请号：PCT/US2016/056464
申请日：2016-10-11
申请人： SILICON BIODEVICES, INC.
发明人： FLORESCU, Octavian , WONG, Daniel , IZYUMIN, Igor
IPC分类号： G01N27/26 , G01N27/416 , G01N33/50 , G01N33/53 , G01N33/543
CPC分类号： G01N33/5302 , B01L3/502761 , B01L2200/0605 , B01L2200/0631 , B01L2200/0668 , B01L2200/10 , B01L2300/0636 , B01L2300/0681 , B01L2400/0406 , B01L2400/043 , G01N27/745
摘要： A stand-alone assay system for POC IVD that is fast, easy to use, inexpensive and delivers laboratory quality results for one or more target analytes from a small volume of unprocessed aqueous sample is disclosed. The stand-alone assay system is a disposable digital device. The stand-alone assay system integrates a sampling system that relies on users swiping a lanced finger containing an unprocessed aqueous sample such as whole blood across a sample inlet to transfer or deposit the unprocessed aqueous sample on to a membrane filter or into a capillary. The stand-alone assays system may have one or more wireless modules for wirelessly transmitting assay information. The wireless modules can receive or transmit user information like patient ID or assay information like time, location or calibration values. The stand-alone assay system can display and transmit the assay information simultaneously. The stand-alone assays system can transmit the assay information through more than one wireless modules simultaneously.
摘要翻译：公开了一种用于POC IVD的独立测定系统，其快速，易于使用，廉价并且为来自少量未处理的水样品的一种或多种目标分析物提供实验室质量结果。独立测定系统是一次性数字设备。独立测定系统集成了一个取样系统，该系统依赖于用户在整个样品入口上滑动含有未处理的含水样品（例如全血）的穿透指纹，以将未处理的水样品转移或沉积到膜过滤器或毛细管中。独立测定系统可以具有用于无线传送测定信息的一个或多个无线模块。无线模块可以接收或发送用户信息，如患者ID或测定信息，如时间，位置或校准值。独立测定系统可以同时显示和传输测定信息。独立测定系统可以通过多个无线模块同时传输测定信息。

6. 发明公开

EP2625504A1 MAGNETIC PARTICLE BASED BIOSENSOR 有权转让
标题翻译： ON磁粉生物传感器
公开(公告)号：EP2625504A1
公开(公告)日：2013-08-14
申请号：EP11831722.1
申请日：2011-10-07
申请人： Silicon Biodevices, Inc.
发明人： FLORESCU, Octavian
IPC分类号： G01N21/00
CPC分类号： G01N33/54366 , G01N15/1436 , G01N21/17 , G01N21/253 , G01N21/274 , G01N21/78 , G01N33/54326 , G01N2201/062 , G01V8/20
摘要： A biosensor system and method of its use for detecting particles on the surface of an integrated circuit is disclosed. The system can include a light source and a plurality of optical sensors formed on an integrate circuit. The particles can be positioned the surface of the integrated circuit whereby the particles can cast a shadow or shadows that reduces the amount of light transmitted from the light source to the optical sensors. The surface of the integrated circuit can include one or more optical sensing areas whereby the presence of one or more particles may significantly or measurably reduce the amount of light incident on one or more optical sensor.

7. 发明授权

EP2502075B1 FILTRATION DEVICE FOR ASSAYS 有权
标题翻译：滤波ASSAYS
公开(公告)号：EP2502075B1
公开(公告)日：2015-07-15
申请号：EP10830336.3
申请日：2010-11-16
申请人： Silicon Biodevices, Inc.
发明人： FLORESCU, Octavian
IPC分类号： G01N33/543 , G01N33/553
CPC分类号： G01N33/54333 , B01L3/502753 , B01L2200/0647 , B01L2200/12 , B01L2300/0636 , B01L2300/0681 , B01L2300/0874 , B01L2400/043 , G01N33/54326 , G01N33/54386 , G01N2458/00 , Y10T137/8013 , Y10T436/25375

8. 发明公开

EP2502075A1 FILTRATION DEVICE FOR ASSAYS 有权
标题翻译：滤波ASSAYS
公开(公告)号：EP2502075A1
公开(公告)日：2012-09-26
申请号：EP10830336.3
申请日：2010-11-16
申请人： Silicon Biodevices, Inc.
发明人： FLORESCU, Octavian
IPC分类号： G01N33/553
CPC分类号： G01N33/54333 , B01L3/502753 , B01L2200/0647 , B01L2200/12 , B01L2300/0636 , B01L2300/0681 , B01L2300/0874 , B01L2400/043 , G01N33/54326 , G01N33/54386 , G01N2458/00 , Y10T137/8013 , Y10T436/25375
摘要： A device and method for filtering blood is disclosed herein. The device can filter blood and attach analytes within the blood to magnetic particles. The analytes can then be strongly bound to an analyzing device by a magnetic force. The analytes can then be counted by the analyzing device and the result can be displayed.

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