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1. 发明申请

WO03009204A3 PHARMACEUTICAL PATIENT INFORMATION SYSTEM 审中-公开
标题翻译：中药病人信息系统
公开(公告)号：WO03009204A3
公开(公告)日：2003-10-09
申请号：PCT/DE0202452
申请日：2002-07-04
申请人： SIEMENS AG , ABRAHAM-FUCHS KLAUS , BIEGER JOHANNES , EISERMANN UWE , HENGERER ARNE , RUMPEL EVA , SCHMIDT KAI-UWE , TIETZE DANIEL
发明人： ABRAHAM-FUCHS KLAUS , BIEGER JOHANNES , EISERMANN UWE , HENGERER ARNE , RUMPEL EVA , SCHMIDT KAI-UWE , TIETZE DANIEL
IPC分类号： A61J3/00 , A61G12/00 , G06F17/30 , G06F19/00 , G06Q50/22
CPC分类号： G06Q50/22 , G06F19/326 , G06F19/3456 , G16H50/20
摘要： Patient information system for the provision of individual-specific information on the effects and risks of a medicament with an expert system, in which relevant data on the medicament, for example, compositions, application area, contra-indications, mode of action, risks and side-effects are stored. Said expert system is embodied such that, on a user inquiry about a particular medicament by inputting particular personal status data about the user, an individual user information reply, which matches the personal status data including the education and the knowledge state of the user - (a personalised enclosure) is generated comprising all relevant data, excluding only that data on the medicament which need not be introduced according to the special requirements of the user.
摘要翻译：用于创建personenspe患者信息系统 - 关于效果和药物的风险与专家系统的特定信息，在药物的相关大个，如组合物，应用，禁忌症，的作用，风险和副作用模式的字段被存储，其中所述专家系统以这样的方式构造包括教育和用户的知识 - - 用户请求到特定的药，说明用户，个人，对个人电流条件数据的具体的个人状态数据时创建基于用户信息（个性化说明手册），全重 - 相关包含数据并仅排除特定请求用户的无关紧要的数据。

2. 发明专利

JP2004358244A Detection method and apparatus of at least one substance in metabolism process of organism 审中-公开
公开(公告)号：JP2004358244A
公开(公告)日：2004-12-24
申请号：JP2004157548
申请日：2004-05-27
申请人： Siemens Ag , シーメンスアクチエンゲゼルシヤフトSiemens Aktiengesellschaft
发明人： ABRAHAM-FUCHS KLAUS , GAREUS RALPH , HENGERER ARNE , SIEBER HEIKE
IPC分类号： A61B10/00 , A61B5/00 , A61B5/07 , A61K49/00 , A61K51/00
CPC分类号： A61B5/14556 , A61B5/07 , A61B5/14532 , A61B5/1455 , A61B5/14552 , A61B5/415 , A61B5/418 , A61B5/681 , A61B5/6816 , A61B5/6817
摘要： PROBLEM TO BE SOLVED: To provide an improved method and apparatus for detection of at least one substance in a metabolism process of organisms capable of especially detecting substances which it is difficult to detect in organisms. SOLUTION: In the detection method of at least one substance in the metabolism process, a molecular enhancer with which an organism is administered capable of enhancing the substance is continuously detected on time in at least one part of the organism. COPYRIGHT: (C)2005,JPO&NCIPI

3. 发明专利

JP2008179637A Magnetic resonance contrast agent comprising iron-binding protein 审中-公开
标题翻译：包含铁结合蛋白的磁共振对比剂
公开(公告)号：JP2008179637A
公开(公告)日：2008-08-07
申请号：JP2008010553
申请日：2008-01-21
申请人： Siemens Ag , シーメンスアクチエンゲゼルシヤフトSiemens Aktiengesellschaft
发明人： HENGERER ARNE
IPC分类号： A61K49/00 , A61B5/055 , G01R33/28
CPC分类号： C07K14/22 , A61K49/14 , A61K49/186 , A61K49/1863 , A61K49/1866 , B82Y5/00 , C07K14/285 , C07K2319/01
摘要： PROBLEM TO BE SOLVED: To provide a magnetic resonance contrast agent that is suitable for specifically bonding to a biological structure, particularly bonding to iron effectively. SOLUTION: The magnetic resonance contrast agent can bond to a biological structure in the body of a mammal through a bonding component, where the bonding component comprises an isolated polypeptide, where the polypeptide comprises a first amino acid sequence of a bacterial iron-binding protein or a derivative thereof, where the bacterial iron-binding protein or a derivative thereof exhibits iron-binding activities. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供适合于特异性结合生物结构的磁共振造影剂，特别是有效地与铁结合。解决方案：磁共振造影剂可以通过粘合成分与哺乳动物体内的生物结构结合，其中结合成分包含分离的多肽，其中多肽包含细菌铁载体的第一氨基酸序列，结合蛋白或其衍生物，其中细菌铁结合蛋白或其衍生物显示出铁结合活性。版权所有（C）2008，JPO＆INPIT

4. 发明专利

JP2002312477A NETWORKED EXPERT SYSTEM FOR AUTOMATED EVALUATION AND QUALITY CONTROL OF MEDICAL POINT OF CARE LABORATORY MEASUREMENT DATA 审中-公开
公开(公告)号：JP2002312477A
公开(公告)日：2002-10-25
申请号：JP2002033294
申请日：2002-02-12
申请人： SIEMENS AG
发明人： ABRAHAM-FUCHS KLAUS , HENGERER ARNE
IPC分类号： G06F19/00 , G06Q50/24 , G16H10/60 , G06F17/60
摘要： PROBLEM TO BE SOLVED: To allow a center diagnosis and laboratory to favorably provide expertise for patients without carrying a specimen. SOLUTION: This network expert system(ES) for automated evaluation and quality control of medical point of care laboratory measurement data is used for connecting measurement devices in the practice for medical activities of treating doctors to a center ES via data lines or network. The ES works as a data collection and diagnosis system for virtual laboratory to permit the treating doctors to evaluate and judge the medial point of care data and make medical plans complemented by networking between a storage system having latest medical expertise and an electronic data bank for patient data if there are implemented rules and insurance.

5. 发明专利

JP2006176512A Method for selecting contrast medium for carrying out imaging examination of patient and contrast medium 审中-公开
标题翻译：选择对照中心进行成像检查和对比中介的方法
公开(公告)号：JP2006176512A
公开(公告)日：2006-07-06
申请号：JP2005364492
申请日：2005-12-19
申请人： Siemens Ag , シーメンスアクチエンゲゼルシヤフトSiemens Aktiengesellschaft
发明人： HENGERER ARNE
IPC分类号： A61K49/00 , A61B5/055 , A61K45/00 , A61K47/46 , G01N21/64 , G01R33/28 , G01R33/30 , G01R33/465 , G01R33/48
CPC分类号： G01N33/58 , A61K49/0002
摘要： PROBLEM TO BE SOLVED: To provide the use of a molecular imaging contrast medium in diagnosis by a method for selecting a suitable contrast medium and to provide improved utilization of molecular imaging for therapy planning and therapy monitoring.
SOLUTION: A tissue sample is collected from a patient (18) and the tissue sample is divided into a plurality of individual samples. The contrast medium (22) binding to a specific target structure (20) in the tissue is added to each individual sample. Furthermore, the individual sample is then examined by a method for examination in order to determine the suitability of the various contrast media for the imaging examination of the patient.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：通过选择合适的造影剂的方法提供分子成像造影剂在诊断中的应用，并提供用于治疗计划和治疗监测的分子成像的改进的利用。解决方案：从患者（18）收集组织样品，并将组织样品分成多个单个样品。将结合到组织中的特定目标结构（20）的造影剂（22）添加到每个单独的样品中。此外，然后通过用于检查的方法检查单个样品，以便确定用于患者的成像检查的各种造影剂的适合性。版权所有（C）2006，JPO＆NCIPI

6. 发明专利

JP2003232736A METHOD AND APPARATUS FOR FORMING OPTICAL IMAGE 审中-公开
公开(公告)号：JP2003232736A
公开(公告)日：2003-08-22
申请号：JP2003009235
申请日：2003-01-17
申请人： SIEMENS AG
发明人： ARNDT FRANK , HENGERER ARNE , MERTELMEIER THOMAS DR , PFISTER MARCUS
IPC分类号： A61B5/00 , G01N21/64 , G01N21/78 , G03B15/03
摘要： PROBLEM TO BE SOLVED: To generate radiation necessary to excite luminescence light at low cost and nevertheless to gain a sufficient illumination intensity for desired luminescence inspection. SOLUTION: The method for forming an optical image particularly for small animals enables an inspecting object (3) to be given a contrast medium capable of being optically activated, and to be irradiated by a plurality of LEDs. Luminescence light (L) excited by the irradiation is detected by a detector (27). The LEDs (D1, D2,..., D12) have particularly different emission wavelengths. In particular, there is a combination of different spectral filters (K1, K2, K3) including in structural units thereof each one excitation filter (15) selecting an excitation wavelength from a light beam (S) emitted by an excitation source (9), each one luminescence filter (23) removing wavelengths residing away from an emission maximum the luminescence light (L) expects. COPYRIGHT: (C)2003,JPO

7. 发明申请

WO02064826A2 NETWORK FOR EVALUATING DATA OBTAINED IN A BIOCHIP MEASUREMENT DEVICE 审中-公开
标题翻译：用于评估生物测量设备中获得的数据的网络
公开(公告)号：WO02064826A2
公开(公告)日：2002-08-22
申请号：PCT/EP0201565
申请日：2002-02-14
申请人： SIEMENS AG , NANOGEN INC
发明人： ABRAHAM-FUCHS KLAUS , HENGERER ARNE , GALLAHUE KIERAN T , GOSCH GREG , O'CONNELL JAMES P , WINDHAB NORBERT
IPC分类号： G01N37/00 , G06F19/00 , G06F19/24 , G06F19/28 , G06Q50/00 , C12Q1/68
CPC分类号： G06F19/28 , G06F19/24 , G16H10/20
摘要： In a method and a network for evaluating medical data in a cli-nical study, biochips containing patient samples with multiple biomolecular markers are tested in a number of point of care test devices respectively at point of care sites. Each test of each biochip sample produces a diagnostic result, which is entered into the electronic patient record for the patient who produced the sample. A follow-up examination is subsequently conducted for each patient, and the results of the follow-up examination are also entered into that patient's electronic patient record. The follow-up results indicate whether the diagnostic test result was a false positive, a false negative or correct. The follow-up data and the original diagnostic results from all point of care sites are electroni-cally transmitted to a remote server, which has access to an expert system which uses the test results and the follow-up data to automatically devise a measurement protocol for a selected pathology.
摘要翻译：在社区研究中用于评估医学数据的方法和网络中，分别在护理部位的许多点护理测试装置中测试含有具有多个生物分子标记的患者样品的生物芯片。每个生物芯片样品的每个测试产生诊断结果，其被输入到生产样品的患者的电子病人记录中。随后对每名患者进行随访检查，随访检查结果也纳入该患者的电子病历。随访结果表明诊断检查结果是假阳性，假阴性或正确。来自所有点护理站点的后续数据和原始诊断结果被电子传输到远程服务器，该远程服务器可以访问使用测试结果的专家系统和后续数据来自动设计测量协议用于选定的病理学。

8. 发明申请

WO02064038A3 SYSTEM FOR EVALUATING DATA OBTAINED IN A BIOCHIP MEASUREMENT DEVICE 审中-公开
标题翻译：用于评估在生物测量装置中获得的数据的系统
公开(公告)号：WO02064038A3
公开(公告)日：2003-02-13
申请号：PCT/EP0201580
申请日：2002-02-14
申请人： SIEMENS AG , NANOGEN INC
发明人： ABRAHAM-FUCHS KLAUS , GALLAHUE KIERAN T , GOSCH GREG , HENGERER ARNE , O'CONNELL JAMES P , WINDHAB NORBERT
IPC分类号： A61B5/00 , A61B10/00 , B01J19/00 , G01N33/48 , G06F3/00 , G06F19/00 , G06F19/20
CPC分类号： G16H10/40 , G06F19/20 , G16H50/20
摘要： A disposable biochip is provided which contains a patient sample with multiple biomolecular markers, as well as a biochip identifier which characterizes the biochip. The biochip is inserted into a point of care test device, which reads the biochip identifier. The point of care test device is in communication with a remote server, and transmits the data characterizing the biochip to the remote server. The remote server selects one of the measurement protocols for testing the sample based on the transmitted data characterizing the biochip. The measurement protocol is transmitted back to the point of care test device via the data link, and the test device conducts testing of the sample using the measurement protocol. The test results are evaluated in an expert system, and a diagnostic result is displayed at the point of care test device.
摘要翻译：提供了一次性生物芯片，其包含具有多个生物分子标记的患者样品，以及表征生物芯片的生物芯片标识符。将生物芯片插入护理测试装置，读取生物芯片标识符。护理测试装置与远程服务器通信，并将表征生物芯片的数据发送到远程服务器。远程服务器根据表征生物芯片的传输数据，选择测试协议之一进行测试。测量协议通过数据链路传送回护理测试设备，测试设备使用测量协议对样本进行测试。测试结果在专家系统中进行评估，诊断结果显示在护理测试设备的位置。

9. 发明专利

DE102014218445A1 Vorrichtung und Verfahren zur Positionsbestimmung eines medizinischen Instrumentes 未知
公开(公告)号：DE102014218445A1
公开(公告)日：2016-03-17
申请号：DE102014218445
申请日：2014-09-15
申请人： SIEMENS AG
发明人： GRODZKI DAVID , HAUSOTTE ANNEMARIE , HEISMANN BJÖRN , SCHMIDT SEBASTIAN , HENGERER ARNE , KELLER-REICHENBECHER MARK-ALEKSI
IPC分类号： A61B34/20 , A61B5/055 , G01R33/02 , G01R33/07 , G01R33/28
摘要： Die vorliegende Erfindung beschreibt eine Vorrichtung (1) zur Positionsbestimmung eines medizinischen Instrumentes (50) innerhalb eines Patientenaufnahmeraumes (14) eines Magnetresonanztomografiegerätes (10), wobei die Vorrichtung (1) ein Sensormittel (52) und ein Rechen- und Steuermittel (70) umfasst, wobei das Sensormittel (52) an oder in dem medizinischen Instrument (50) angeordnet ist, wenigstens einen Magnetfeldsensor (54) zur Gewinnung von Messwerten einer magnetischen Flussdichte umfasst und mit dem Rechen- und Steuermittel (70) zur Datenübermittlung verbindbar ist und wobei das Rechen und Steuermittel (70) zur Steuerung von Magnetfeldern des Magnetresonanztomografiegerätes (10) und zur Positionsbestimmung des medizinischen Instrumentes (50) ausgeführt ist, wobei in die Positionsbestimmung des medizinischen Instrumentes (50) die Messwerte des wenigstens einen Magnetfeldsensors (54) und Steuersignale zur Steuerung der Magnetfelder des Magnetresonanztomografiegerätes (10) eingehen. Weiter beschreibt die Erfindung ein entsprechendes Verfahren zur Positionsbestimmung eines medizinischen Instrumentes (50) innerhalb eines Patientenaufnahmeraumes (14) eines Magnetresonanztomografiegerätes (10).

10. 发明专利

DE102007004283B4 Magnetresonanz-Kontrastmittel mit eisenbindendem Protein 未知
公开(公告)号：DE102007004283B4
公开(公告)日：2011-03-03
申请号：DE102007004283
申请日：2007-01-23
申请人： SIEMENS AG
发明人： HENGERER ARNE
IPC分类号： A61K49/14 , C07K14/195 , C07K14/22 , C07K14/285 , C12N15/62

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