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1. 发明申请

WO2016175337A1 METHOD OF REMOVING PROTEIN AGGREGATE 审中-公开
标题翻译：去除蛋白质聚集体的方法
公开(公告)号：WO2016175337A1
公开(公告)日：2016-11-03
申请号：PCT/JP2016/063937
申请日：2016-04-28
申请人： SHOWA DENKO K.K.
发明人： KOKIDO Yuzuru , MATSUI Natsuno , AOKI Hirobumi , YONEDA Tadashi
IPC分类号： C07K1/18 , C07K16/00
CPC分类号： C07K1/18 , A61K39/39591 , C07K16/00 , C07K16/065
摘要： Provided is a method of removing a protein aggregate which can obtain a useful protein monomer in a high yield and a high purity as a raw material of a pharmaceutical product or the like. The method of removing a protein aggregate includes: a step of making the monomer of a protein and the aggregate of proteins adsorb to the column by making a solution containing a monomer of a protein and an aggregate of proteins pass through a column containing a hard porous polymer self-supporting structure to which a strong cation exchange group is fixed; and a step of making a mobile phase consisting of a mixed solution of a buffer solution and an ionic buffer solution pass through the column to which the monomer of a protein and the aggregate of proteins are adsorbed, to selectively elute the monomer of a protein.
摘要翻译：提供一种去除可以以高产率和高纯度获得有用的蛋白质单体作为药物等的原料的蛋白质聚集体的方法。去除蛋白质聚集体的方法包括：通过制备含有蛋白质单体和蛋白质聚集体的溶液通过含有硬质多孔体的柱子，使蛋白质的单体和蛋白质的聚集体吸附到塔的步骤强阳离子交换基团固定的聚合物自支撑结构; 并且使由缓冲溶液和离子缓冲溶液的混合溶液组成的流动相通过蛋白质的单体和蛋白质聚集体所吸附的柱的步骤，以选择性地洗脱蛋白质的单体。

2. 发明公开

EP2952573A1 METHOD FOR PROMOTING GROWTH OF GREEN ALGAE 有权
标题翻译：促进绿藻生长的方法
公开(公告)号：EP2952573A1
公开(公告)日：2015-12-09
申请号：EP14745336.9
申请日：2014-02-04
申请人： Showa Denko K.K.
发明人： OHTAKE Noriko , YONEDA Tadashi
IPC分类号： C12N1/12
CPC分类号： C12N1/12 , C12N13/00 , C12P23/00
摘要： Provided is a method of culturing green algae which promotes the growth of the green algae which is in a state of being a green swarm cell by irradiating the green algae that accumulate astaxanthin with an artificial light, in which the green algae are grown in a liquid medium while maintaining a state in which the color of a culture solution of the green algae is green or brown by intermittently radiating a red illumination light while continuously radiating a blue illumination light.
摘要翻译：本发明提供一种绿藻类的培养方法，该绿藻类通过对蓄积有虾青素的绿藻进行照射，并使绿藻在液体中生长而成的人造光来促进作为绿群细胞的绿藻的生长同时通过间歇地照射红色照明光同时保持其中绿藻培养液的颜色为绿色或棕色的状态，同时连续地照射蓝色照明光。

3. 发明公开

EP3395324A1 ANTI-AGING AGENT AND ANTI-AGING COMPOSITION FOR SKIN 审中-公开
公开(公告)号：EP3395324A1
公开(公告)日：2018-10-31
申请号：EP16878146.6
申请日：2016-10-28
申请人： Showa Denko K.K.
发明人： NAKAGAMI Yuko , YAMAKI Shinji , FUJITA Ichiro , YONEDA Tadashi
IPC分类号： A61K8/60 , A61Q19/08
CPC分类号： A61K8/60 , A61K8/73 , A61K31/7016 , A61K31/702 , A61Q19/08
摘要： Provided is an anti-aging agent for skin which contains, as an active component, an inositol derivative in which a monosaccharide or an oligosaccharide is bonded to inositol, in which a total amount of the monosaccharide or the oligosaccharide bonded to one inositol molecule is 2 or greater in terms of monosaccharide unit.

4. 发明授权

EP2952575B1 METHOD FOR PROMOTING GROWTH OF GREEN ALGAE 有权
标题翻译：促进绿藻生长的方法
公开(公告)号：EP2952575B1
公开(公告)日：2018-04-04
申请号：EP14746315.2
申请日：2014-02-04
申请人： Showa Denko K.K.
发明人： OHTAKE Noriko , YONEDA Tadashi
IPC分类号： C12N1/12 , C12N13/00 , C12P23/00
CPC分类号： C12N1/12 , C12N13/00 , C12P23/00
摘要： Provided is a method of culturing green algae which promotes the growth of the green algae which is in a state of being a green swarm cell by irradiating the green algae that accumulate astaxanthin with an artificial light, in which the green algae are grown in a liquid medium while maintaining a state in which the color of a culture solution of the green algae is green or brown by intermittently radiating a blue illumination light while continuously radiating a red illumination light.

5. 发明公开

EP2952575A1 METHOD FOR PROMOTING GROWTH OF GREEN ALGAE 有权
标题翻译：促进绿藻生长的方法
公开(公告)号：EP2952575A1
公开(公告)日：2015-12-09
申请号：EP14746315.2
申请日：2014-02-04
申请人： Showa Denko K.K.
发明人： OHTAKE Noriko , YONEDA Tadashi
IPC分类号： C12N1/12
CPC分类号： C12N1/12 , C12N13/00 , C12P23/00
摘要： Provided is a method of culturing green algae which promotes the growth of the green algae which is in a state of being a green swarm cell by irradiating the green algae that accumulate astaxanthin with an artificial light, in which the green algae are grown in a liquid medium while maintaining a state in which the color of a culture solution of the green algae is green or brown by intermittently radiating a blue illumination light while continuously radiating a red illumination light.
摘要翻译：本发明提供一种绿藻类的培养方法，该绿藻类通过对蓄积有虾青素的绿藻进行照射，并使绿藻在液体中生长而成的人造光来促进作为绿群细胞的绿藻的生长同时通过间歇地照射蓝色照明光同时保持其中绿藻的培养液的颜色为绿色或棕色的状态，同时连续照射红色照明光。

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