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1. 发明专利

DE602006014089D1 PROBENINJEKTOR, PROBENINJEKTIONSVERFAHREN UND VORRICHTUNG ZUR FLÜSSIGKEITSCHROMATOGRAPHIE 未知
公开(公告)号：DE602006014089D1
公开(公告)日：2010-06-17
申请号：DE602006014089
申请日：2006-01-20
申请人： SHISEIDO CO LTD
发明人： HIRAYAMA AYA , SHIROTA OSAMU
IPC分类号： G01N30/16 , G01N30/24

2. 发明公开

EP2362214A4 SAMPLE INJECTION DEVICE, SAMPLE INJECTION METHOD, AND LIQUID CHROMATOGRAPHY DEVICE 有权
标题翻译：样装置，对于液体样品注射的方法和装置
公开(公告)号：EP2362214A4
公开(公告)日：2011-11-16
申请号：EP09802941
申请日：2009-07-28
申请人： SHISEIDO CO LTD
发明人： HIRAYAMA AYA , SHIROTA OSAMU , MITA MASASHI , MIBAYASHI KAZUHIKO
IPC分类号： G01N30/16 , F16K11/00 , G01N30/20 , G01N30/24 , G01N35/10
CPC分类号： G01N30/20 , G01N30/16 , G01N30/24 , G01N35/1004 , G01N35/1097

3. 发明公开

EP2444477A4 CONTAINER FOR FORMATION OF AGGREGATED CELL MASS, AND METHOD FOR FORMATION OF AGGREGATED CELL MASS 审中-公开
标题翻译：容器聚合小区MASS和方法用于编队聚合小区质量的形成
公开(公告)号：EP2444477A4
公开(公告)日：2013-01-09
申请号：EP10789497
申请日：2010-06-15
申请人： SHISEIDO CO LTD
发明人： FUJIWARA SHIGEYOSHI , TAKEI KEIGO , HIRAYAMA AYA , SUDA YUKIMITSU
IPC分类号： C12M1/00 , C08J7/04 , C08J7/12 , C09D133/14 , C12M3/00 , C12N5/07
CPC分类号： C12M23/20 , C12N5/062 , C12N5/0667 , C12N5/0671 , C12N5/0693 , C12N2533/30 , G01N33/5082
摘要： A container for forming a cell aggregate is provided in which a group represented by a general formula of: (in the formula, each of R 1 , R 2 , and R 3 is independently a an alkyl group with a carbon number of 1 or more and 6 or less and m is an integer of 2 or more and 6 or less.) and at least one of an amino group, a carboxyl group, and a hydroxyl group are present near a surface thereof.

4. 发明公开

EP1843153A4 SAMPLE INJECTOR, SAMPLE INJECTING METHOD AND LIQUID CHROMATOGRAPHY EQUIPMENT 有权
标题翻译：进样器，进样的方法和设备用于液相色谱
公开(公告)号：EP1843153A4
公开(公告)日：2009-09-02
申请号：EP06712112
申请日：2006-01-20
申请人： SHISEIDO CO LTD
发明人： HIRAYAMA AYA , SHIROTA OSAMU
IPC分类号： G01N30/16 , G01N30/24
CPC分类号： G01N30/20 , G01N30/24
摘要： A sample injector, a sample injecting method and liquid chromatography equipment which control the flow of a moving phase using a selector valve. The sample injector comprises a port connected with a separation column, a pump for feeding a moving phase, a pair of sample injection needles, a syringe, and a valve for connecting one sample injection needle with any one of the pump and the syringe selectively and using the other sample injection needle as a pump. When one sample injection needle is fixed to the port by operating the valve, that sample injection needle is connected with the pump. When the other sample injection needle is fixed to the port, one sample injection needle is connected with the syringe and the other sample injection needle is connected with the pump.

5. 发明专利

JP2009229209A Surface modification method, surface modifying material and analytical method 审中-公开
标题翻译：表面改性方法，表面改性材料和分析方法
公开(公告)号：JP2009229209A
公开(公告)日：2009-10-08
申请号：JP2008074287
申请日：2008-03-21
申请人： Shiseido Co Ltd , 株式会社資生堂
发明人： HIRAYAMA AYA , MIYAZAWA KAZUYUKI
IPC分类号： G01N33/543
摘要： PROBLEM TO BE SOLVED: To provide a surface modification method capable of uniformly introducing a phosphorylcholine analogous group into a gold substrate.
SOLUTION: The surface modification method comprises the steps of: forming a self-assembled monolayer of a thiol having a reactive functional group via a gold-thiol bond on the surface of the gold substrate; allowing a surface modifier having a functional group represented by the general formula to bond with the self-assembled monolayer linked to the surface of the gold substrate by reacting the surface modifier with the self-assembled monolayer linked to the surface of the gold substrate. In the formula, R1, R2, and R3 individually represent a 1-6C alkyl group; m represents an integer of 2 to 6; and n is 1 or 2.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供能够将磷酰胆碱类似基团均匀地引入金基底中的表面改性方法。解决方案：表面改性方法包括以下步骤：通过金基底表面上的金 - 硫醇键形成具有反应性官能团的硫醇的自组装单层; 允许具有由通式表示的官能团的表面改性剂通过使表面改性剂与连接到金基底的表面的自组装单层反应而与与金基底的表面连接的自组装单层结合。在该式中，R 1，R 2和R 3各自表示1-6C烷基; m表示2〜6的整数，并且n为1或2.版权所有（C）2010，JPO＆INPIT

6. 发明专利

JP2007119643A Method for treating the surface of material 有权
标题翻译：用于处理材料表面的方法
公开(公告)号：JP2007119643A
公开(公告)日：2007-05-17
申请号：JP2005315102
申请日：2005-10-28
申请人： Shiseido Co Ltd , 株式会社資生堂
发明人： MIYAZAWA KAZUYUKI , HIRAYAMA AYA
IPC分类号： C09K3/00 , C04B41/89 , C23C28/00 , D06M11/44 , D06M11/79 , D06M13/513
摘要： PROBLEM TO BE SOLVED: To provide a method for readily introducing a phosphorylcholine group in very good efficiency to an arbitrary material, the surface treatment of which by using a conventional silane coupler has been difficult, by reacting the surface with a specific phosphorylcholine group-containing silane coupler.
SOLUTION: The method for treating the surface of the material comprises subjecting the surface of the material to vapor deposition of a metal oxide or silica, and treating the deposited surface with a phosphorylcholine-containing compound represented by formula (1) (wherein, m is 2-6; n is 1-4; X
1 , X
2 and X
3 are each independently a methoxy group, an ethoxy group or a halogen, with the proviso that up to two of the X
1 , X
2 and X
3 can be any of a methyl group, an ethyl group, a propyl group, an isopropyl group, a butyl group and an isobutyl group).
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：为了提供容易地将磷酸胆碱基团以非常好的效率引入任意材料的方法，通过使用常规的硅烷偶联剂进行表面处理是困难的，通过使表面与特定的磷酸胆碱含硅基团的硅烷偶联剂。解决方案：用于处理材料表面的方法包括对材料的表面进行气相沉积金属氧化物或二氧化硅，并用由式（1）表示的含磷酰胆碱的化合物处理沉积的表面（其中，m为2-6; n为1-4; X 1 ，X 2 和X 3 各自为甲氧基，乙氧基或卤素，条件是至多两个X 1，X SP 3，X 3，SP 3可以是任何甲基基，乙基，丙基，异丙基，丁基和异丁基）。版权所有（C）2007，JPO＆INPIT

7. 发明专利

JP2012078346A Method for producing filler, filler, and column 有权
标题翻译：生产填料，填料和柱的方法
公开(公告)号：JP2012078346A
公开(公告)日：2012-04-19
申请号：JP2011158820
申请日：2011-07-20
申请人： Shiseido Co Ltd , 株式会社資生堂
发明人： HIROE YOSHIHISA , HIRAYAMA AYA
IPC分类号： G01N30/88 , B01J20/281 , B01J20/30
CPC分类号： B01J20/282 , B01J20/283 , B01J20/3204 , B01J20/3219 , B01J20/3259
摘要： PROBLEM TO BE SOLVED: To provide a method for producing a filler having high endurance, reducing a residual amount of a hydroxyl group, and capable of introducing an ion-exchange group; to provide the filler produced using the method for producing the filler; and to provide a column filled with the filler.SOLUTION: A method for producing a filler, includes: a first step of reacting inorganic particles each having a hydroxyl group with a silane coupling agent comprising a silane coupling having an alkenyl group having 2 to 8 inclusive of carbon atoms and/or an alkynyl group having 2 to 7 inclusive of carbon atoms; a second step of reacting the inorganic particles that have been reacted with the silane coupling agent with a compound having a hydrosilyl group and a primary amino group protected by a protecting group; and a third step of deprotecting the inorganic particles which have been reacted with the compound having the hydrosilyl group and the primary amino group protected by the protecting group to produce a primary amino group.
摘要翻译：待解决的问题：提供一种制备具有高耐久性，减少残留量的羟基并能够引入离子交换基团的填料的方法; 以提供使用生产填料的方法生产的填料; 并提供填充有填料的柱。解决方案：一种制备填料的方法，包括：使具有羟基的无机颗粒与包含具有2至8个含有碳原子的烯基的硅烷偶联的硅烷偶联剂反应的第一步骤和/或具有2〜7个碳原子的炔基; 使已与硅烷偶联剂反应的无机粒子与具有氢保护基保护的氢甲硅烷基和伯氨基的化合物反应的第二工序; 以及与已经与具有氢化甲硅烷基的化合物和被保护基保护的伯氨基反应产生伯氨基的无机颗粒脱保护的第三步骤。版权所有（C）2012，JPO＆INPIT

8. 发明专利

JP2011257570A Anti-fogging lens 有权
标题翻译：防透镜
公开(公告)号：JP2011257570A
公开(公告)日：2011-12-22
申请号：JP2010131588
申请日：2010-06-09
申请人： Shiseido Co Ltd , Tokai Kogaku Kk , 東海光学株式会社 , 株式会社資生堂
发明人： KATO ATSUSHI , HASE KANAME , TAKEI KEIGO , HIRAYAMA AYA
IPC分类号： G02B3/00 , C03C17/30 , C09D5/00 , C09D7/12 , C09D143/00 , C09D143/02 , C09D143/04 , C09D171/02 , C09D183/04 , C09D183/08 , G02B1/10
摘要： PROBLEM TO BE SOLVED: To provide anti-fogging lens having high persistence of anti-fogging performance and facilitating wiping dirt adhered thereto.SOLUTION: On an oxide surface of a substrate, a low friction anti-fogging film having a dynamic friction coefficient of less than 0.5 is formed whose main component is a composition where the below-described hydrophilic substance having a silane reactive group to chemically bond a phosphorylcholine group with the substrate is mixed with a coupling agent selected from a metal alkoxide and a silane compound. Thus, anti-fogging lens having high persistence of anti-fogging performance and facilitating wiping dirt adhered thereto can be provided.
摘要翻译：要解决的问题：提供具有高防雾性能的防雾透镜，并且便于擦拭粘附在其上的污垢。解决方案：在基材的氧化物表面上，形成动摩擦系数小于0.5的低摩擦防雾膜，其主要成分是将具有硅烷反应性基团的下述亲水性物质与将磷酰胆碱基团与底物化学键合与选自金属醇盐和硅烷化合物的偶联剂混合。因此，可以提供具有高的持久性防雾性能并且便于擦拭附着的污垢的防雾透镜。版权所有（C）2012，JPO＆INPIT

9. 发明专利

JP2006201121A Sample injection device, sample injection method, and liquid chromatography unit 有权
标题翻译：样品注射装置，样品注射方法和液相色谱仪
公开(公告)号：JP2006201121A
公开(公告)日：2006-08-03
申请号：JP2005015583
申请日：2005-01-24
申请人： Shiseido Co Ltd , 株式会社資生堂
发明人： HIRAYAMA AYA , SHIROTA OSAMU
IPC分类号： G01N30/16 , G01N30/26
CPC分类号： G01N30/20 , G01N30/24
摘要： PROBLEM TO BE SOLVED: To surely reduce a carrying-over in the present invention, as to a sample injection device, a sample injection method and a liquid chromatography unit capable of controlling a flow of a mobile phase using a change-over valve.
SOLUTION: This device/method/unit has a port 19 connected to a separation column 35, a pump 33 for supplying the mobile phase, a pair of sample injection needles 10A, 10B, a syringe 11, and the valve 15 for connecting the sample injection needle 10A selectively to the pump 33 or the syringe 11, and for connecting the sample injection needle 10B to the pump 33. The sample injection needle 10A is connected to the pump 33 by operating the valve 15, when the sample injection needle 10A is attached to the port 19. The sample injection needle 10A is connected to the syringe 11, and the other side sample injection needle 10B is connected to the pump 33, when the the other side sample injection needle 10B is attached to the port 19.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题为了确保本发明中的携带，对于样品注射装置，可以使用转换来控制流动相的流动的样品注射方法和液相色谱单元阀。解决方案：该装置/方法/单元具有连接到分离柱35的端口19，用于供应流动相的泵33，一对注射针10A，10B，注射器11以及用于将样品注射针10A选择性地连接到泵33或注射器11，并将样品注射针10B连接到泵33.样品注射针10A通过操作阀15连接到泵33，当样品注射针10A连接到端口19.样品注射针10A连接到注射器11，另一侧样品注射针10B连接到泵33，另一侧样品注射针10B连接到端口 19.版权所有（C）2006，JPO＆NCIPI

10. 发明专利

JPH08262004A COLUMN FILLER AND ITS PREPARATION 失效
公开(公告)号：JPH08262004A
公开(公告)日：1996-10-11
申请号：JP9299495
申请日：1995-03-27
申请人： SHISEIDO CO LTD
发明人： HIRAYAMA AYA , KANDA TAKETOSHI , OTSU YUTAKA , YAMAGUCHI MICHIHIRO
IPC分类号： B01J20/283 , B01J20/285 , G01N30/88 , G01N30/48
摘要： PURPOSE: To obtain a filler which is not affected by a mobile phase and whose durability is excellent by a method wherein a hydrophobic sulfone group is bonded to a silicone polymer with which a porous carrier has been coated wholly. CONSTITUTION: As a porous carrier, spherical silica gel which has a pore of 60 to 80Å and which has a particle size of 3 to 50μm is especially preferable. In addition, as a coated silicone polymer, a hydrophobic sulfone group R-X (where R represents a hydrophobic group and X represents a sulfone group) which comprises a double bond is bonded to an -Si-H group so as to form an -Si-R-X group. When this silicone compound is brought into contact with the porous carrier in a gas phase state or a liquid phase state, the silicone compound advances into the inside of every pore of the carrier. Then, the silicone compound is stuck to the substantially whole surface of a pulverulent body so as to be polymerized, and an extremely thin (3 to 30Å) film of the silicone polymer is formed on the carrier. Consequently, it is possible to obtain a filler which is not affected by a polar group (e.g. a furanol group of silica gel) by the pulverulent body, whose infouence on the root of a hydrophobic chemical correction froup due to a mobile phase is small and whose stability and durability are excellent.

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