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1. 发明专利

AU2012244074B2 Methods and compositions for intranasal delivery 未知
公开(公告)号：AU2012244074B2
公开(公告)日：2015-01-15
申请号：AU2012244074
申请日：2012-10-19
申请人： KM BIOLOGICS CO LTD , SHIN NIPPON BIOMEDICAL LABORATORIES LTD
发明人： NAGATA RYOICHI , HARUTA SHUNJI
IPC分类号： A61K39/145 , A61K35/74 , A61K35/76 , A61K39/00 , A61K47/26 , A61K47/38 , A61P31/04 , A61P31/12 , A61P31/16
摘要： Provided herein are methods for generating dry vaccine powder formulations. Dry vaccine powder formulations can be used for intranasal delivery. Also provided are methods for stimulating local mucosal and systemic immunity by intranasal vaccine delivery. See also Figure 17B.

2. 发明专利

ES2874817T3 Procedimiento para generar una formulación de vacuna en polvo seco para suministro intranasal 未知
公开(公告)号：ES2874817T3
公开(公告)日：2021-11-05
申请号：ES13189570
申请日：2011-04-15
申请人： SHIN NIPPON BIOMEDICAL LABORATORIES LTD , KM BIOLOGICS CO LTD
发明人： NAGATA RYOICHI , HARUTA SHUNJI
IPC分类号： A61K39/145 , A61K9/19 , A61K35/74 , A61K35/76 , A61K39/00 , A61K39/05 , A61K39/08 , A61K47/26 , A61K47/38 , A61P31/04 , A61P31/12 , A61P31/16 , H04W4/90
摘要： Un procedimiento para generar una formulación intranasal de vacuna en polvo seco, que comprende: a. preparar una formulación líquida que comprende uno o más antígenos; b. congelar rápidamente la formulación líquida para formar una muestra secada por congelación, en la que la congelación rápida no comprende la congelación por pulverización y en la que la muestra secada por congelación no comprende un adyuvante; y, c. mezclar la muestra secada por congelación con uno o más excipientes para generar la formulación de vacuna intranasal en polvo seco.

3. 发明专利

CA2796593C METHODS AND COMPOSITIONS FOR INTRANASAL DELIVERY 未知
公开(公告)号：CA2796593C
公开(公告)日：2020-12-15
申请号：CA2796593
申请日：2011-04-15
申请人： SHIN NIPPON BIOMEDICAL LABORATORIES LTD
发明人： NAGATA RYOICHI , HARUTA SHUNJI
IPC分类号： A61K47/38 , A61K9/14 , A61K39/00 , A61K39/05 , A61K39/08 , A61K39/145 , A61K47/26 , A61P31/04 , A61P31/12 , A61P31/16 , A61P37/04 , C12N1/20 , C12N7/00 , H04W4/90
摘要： Provided herein are methods for generating dry vaccine powder formulations. Dry vaccine powder formulations can be used for intranasal delivery. Also provided are methods for stimulating local mucosal and systemic immunity by intranasal vaccine delivery.

4. 发明专利

CA2978050C MICRO-ENCAPSULATED AQUACULTURE FEED 未知
公开(公告)号：CA2978050C
公开(公告)日：2019-10-15
申请号：CA2978050
申请日：2016-01-22
申请人： SHIN NIPPON BIOMEDICAL LABORATORIES LTD
发明人： NAGATA RYOICHI , KAWAKAMI YUTAKA
IPC分类号： A23K20/147 , A23K20/00 , A23K40/30 , A23K50/80
摘要： To provide a feed that does not pollute rearing water, improves the immunity activity of leptocephalus larvae, is capable of directly feeding eel leptocephalus, and is capable of effectively inducing the growth of said larvae into glass eels. [Solution] This micro-encapsulated aquaculture feed includes. an oil phase 11 having an oil-soluble nutrient component; a water phase 13 which is present inside the oil phase 11, and which includes a water-soluble nutrient component; and a film 15 which includes the oil phase 11 and the water phase 13. The water-soluble nutrient component includes at least one hydrolysate from among hydrolysates of amino acids, oligopeptides, and proteins.

5. 发明专利

CA2769858C PRIMATE RESTRAINT DEVICE 未知
公开(公告)号：CA2769858C
公开(公告)日：2018-03-13
申请号：CA2769858
申请日：2010-08-06
申请人： SHIN NIPPON BIOMEDICAL LABORATORIES LTD
发明人： NAGATA RYOICHI
IPC分类号： A01K15/04 , A01K1/03 , A01K67/00 , A61D3/00
摘要： A primate restraint device capable of restricting the movement of a monkey and, particularly, capable of facilitating injection or blood collection. A primate restraint device comprising: a containing body having both side surfaces, a top surface, and a bottom surface; a door provided to the rear surface side of the containing body and capable of opening and closing the rear surface side of the containing body by sliding up and down; and a partition wall which is formed so as to close the inside of the containing body from the front surface side and to be movable forward and backward within the containing body and which is configured to be able to be affixed at a desired position within the containing body. The partition wall has provided therein hind-limb protrusion openings from which the hind limbs of the contained primate are caused to protrude to the outside.

6. 发明专利

CA2993242A1 METHODS AND COMPOSITIONS FOR INTRANASAL DELIVERY 未知
公开(公告)号：CA2993242A1
公开(公告)日：2011-10-20
申请号：CA2993242
申请日：2011-04-15
申请人： SHIN NIPPON BIOMEDICAL LABORATORIES LTD
发明人： NAGATA RYOICHI , HARUTA SHUNJI
IPC分类号： A61K9/19 , A61K39/00 , A61K39/05 , A61K39/08 , A61K39/145 , A61P31/04 , A61P31/16 , A61P37/04 , C12N1/20 , C12N7/00 , H04W4/90
摘要： Provided herein are methods for generating dry vaccine powder formulations. Dry vaccine powder formulations can be used for intranasal delivery. Also provided are methods for stimulating local mucosal and systemic immunity by intranasal vaccine delivery.

7. 发明专利

PH12019501711A1 BREEDING WATER FOR ANGUILLIFORMES AND METHOD FOR REARING ANGUILLIFORMES 未知
公开(公告)号：PH12019501711A1
公开(公告)日：2020-06-01
申请号：PH12019501711
申请日：2019-07-25
申请人： SHIN NIPPON BIOMEDICAL LABORATORIES LTD
发明人： NAGATA RYOICHI , KAWAKAMI YUTAKA
IPC分类号： A01K61/10 , A23K20/174 , A23K20/184 , A23K50/80
摘要： [Problem] To provide breeding water for anguilliformes, and a method for rearing anguilliformes using the breeding water, in order to artificially control the transformation of glass eels and the like and produce glass eels and the like in the same size and form with a shorter period until birth. [Solution] Anguilliformes breeding water containing a thyroid hormone such as thyroxine, and a method for rearing anguilliformes including a step for administering a thyroid hormone such as thyroxine, wherein the amount of the thyroid hormone to be administered changes as the anguilliforme fingerling changes from a transformation start phase (stage 1) to a transformation final phase (stage 2), and the amount of the thyroid hormone to be administered in the transformation final phase (stage 2) is less than the amount of the thyroid hormone to be administered in the transformation start phase (stage 1).

8. 发明专利

CA2769856C PRIMATE RESTRAINT DEVICE 未知
公开(公告)号：CA2769856C
公开(公告)日：2017-04-18
申请号：CA2769856
申请日：2010-08-06
申请人： SHIN NIPPON BIOMEDICAL LABORATORIES LTD
发明人： NAGATA RYOICHI
IPC分类号： A01K15/04 , A01K1/03 , A01K67/00 , A61D3/00
摘要： A primate retaining device capable of restraining the movement of a monkey and, particularly, capable of facilitating transnasal administration into the stomach or oral administration. A primate retaining device comprising: a containing body having both side surfaces, a top surface, and a bottom surface; a door provided to the rear surface side of the containing body and capable of opening and closing the rear surface side of the containing body by sliding up and down; and a partition wall which is formed so as to close the inside of the containing body from the front surface side and to be movable forward and backward within the containing body and which is configured to be able to be affixed at a desired position within the containing body. Both the side surfaces are each formed by combining vertical bar members and horizontal bar members into a grid pattern, and at least some of the horizontal bar members of the side surface are curved downward to form chin support sections on which the chin of the contained primate is supported.

9. 发明专利

CA2978050A1 MICRO-ENCAPSULATED AQUACULTURE FEED 未知
公开(公告)号：CA2978050A1
公开(公告)日：2016-07-28
申请号：CA2978050
申请日：2016-01-22
申请人： SHIN NIPPON BIOMEDICAL LABORATORIES LTD
发明人： NAGATA RYOICHI , KAWAKAMI YUTAKA
IPC分类号： A23K20/147 , A23K20/00 , A23K40/30 , A23K50/80
摘要： [Problem] To provide a feed that does not pollute rearing water, improves the immunity activity of leptocephalus larvae, is capable of directly feeding eel leptocephalus, and is capable of effectively inducing the growth of said larvae into glass eels. [Solution] This micro-encapsulated aquaculture feed includes: an oil phase 11 having an oil-soluble nutrient component; a water phase 13 which is present inside the oil phase 11, and which includes a water-soluble nutrient component; and a film 15 which includes the oil phase 11 and the water phase 13. The water-soluble nutrient component includes at least one hydrolysate from among hydrolysates of amino acids, oligopeptides, and proteins.

10. 发明专利

PH12014502610B1 PRIMATE RESTRAINT DEVICE 未知
公开(公告)号：PH12014502610B1
公开(公告)日：2015-01-21
申请号：PH12014502610
申请日：2014-11-21
申请人： SHIN NIPPON BIOMEDICAL LABORATORIES LTD
发明人： NAGATA RYOICHI , KASHIMA MASATOSHI , MAGOTANI HIROAKI
IPC分类号： A01K15/04 , A01K67/00
摘要： When a primate is t restrained by a movable partition wall, friction with vertical bars of a lattice of the partition wall causing damages on roots of limbs of the primate is alleviated to reduce or solve such damages. In a primate restraint device 10 comprising a containing body 20 having both side surfaces, a top surface and a bottom surface, a rear surface door 50 capable of opening and shutting the rear surface side of the containing body 20, and a partition wall 30 formed movably frontward and rearward in the containing body 20 and capable of being fixed at a desired position in the containing body 20, some sites among vertical bar members 31 of the partition wall 30, with which roots of limbs of the primate are brought into contact while the limbs are forced to protrude frontward and restrained, are covered with protective cylinders 33 which are rotatable with respect to the vertical bar members 31.

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