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1. 发明申请

WO2006017400A8 BIOPSY DEVICE WITH SELECTABLE TISSUE RECEIVING APERTURE ORIENTATION AND SITE ILLUMINATION 审中-公开
标题翻译：具有选择性组织的生物装置接收孔径方位和场地照明
公开(公告)号：WO2006017400A8
公开(公告)日：2006-10-05
申请号：PCT/US2005027071
申请日：2005-07-29
申请人： SENORX INC , SHABAZ MARTIN V , QUICK RICHARD L , LOUW FRANK R , LUBOCK PAUL , SAFABASH JASON H
发明人： SHABAZ MARTIN V , QUICK RICHARD L , LOUW FRANK R , LUBOCK PAUL , SAFABASH JASON H
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B17/32 , A61B17/34
CPC分类号： A61B10/0275 , A61B10/0266 , A61B10/0283 , A61B17/32002 , A61B17/3417 , A61B90/30 , A61B2010/0208 , A61B2010/0225 , A61B2017/00473 , A61B2017/00486 , A61B2017/3405 , A61B2090/3908 , A61B2090/3987
摘要： The invention is directed to a system and device for separating and collecting a tissue specimen from a patient target site. The device includes a probe component (11) with an elongated tubular section (15), a penetrating distal tip (16) and a tissue receiving aperture (17) in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member (20) which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device has a driver component (12) to which the probe component is releasably secured. The driver has a drive member (22,23) for adjusting the orientation of the tubular section and one or more drive members (30) for moving the tissue cutting member within the tubular section to sever a tissue specimen. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational.
摘要翻译：本发明涉及一种用于从患者靶位置分离和收集组织标本的系统和装置。该装置包括具有细长管状部分（15）的探针部件（11），远侧末端的管状部分的远端中的穿透远端（16）和组织接收孔（17），以及组织切割构件（20），其可滑动地设置在所述探针构件内，以通过对所述组织切割构件的内腔施加真空来切割通过所述孔被拉入所述装置的内部的组织样本。该装置具有驱动器部件（12），探头部件可释放地固定到该部件上。驱动器具有用于调节管状部分的取向的驱动构件（22,23）和用于移动管状部分内的组织切割构件以切断组织样本的一个或多个驱动构件（30）。赋予组织切割器的运动至少是纵向的，并且优选地也是振动和/或旋转。

2. 发明申请

WO2006017400A3 BIOPSY DEVICE WITH SELECTABLE TISSUE RECEIVING APERTURE ORIENTATION AND SITE ILLUMINATION 审中-公开
标题翻译：具有选择性组织的生物装置接收孔径方位和场地照明
公开(公告)号：WO2006017400A3
公开(公告)日：2006-05-18
申请号：PCT/US2005027071
申请日：2005-07-29
申请人： SENORX INC , SHABAZ MARTIN V , QUICK RICHARD L , LOUW FRANK R , LUBOCK PAUL , SAFABASH JASON H
发明人： SHABAZ MARTIN V , QUICK RICHARD L , LOUW FRANK R , LUBOCK PAUL , SAFABASH JASON H
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B17/32 , A61B17/34
CPC分类号： A61B10/0275 , A61B10/0266 , A61B10/0283 , A61B17/32002 , A61B17/3417 , A61B90/30 , A61B2010/0208 , A61B2010/0225 , A61B2017/00473 , A61B2017/00486 , A61B2017/3405 , A61B2090/3908 , A61B2090/3987
摘要： The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component (11) with an elongated tubular section (15), a penetrating distal tip (16) and a tissue receiving aperture (17) in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member (20) which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component (12) to which the probe component is releasably secured. The driver has a drive member (22,23) for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members (30) for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational to effectively separate a tissue specimen from tissue extending through the aperture in the tubular section.
摘要翻译：本发明涉及一种用于从患者内的目标部位分离和收集组织标本的系统和装置。该装置包括具有细长管状部分（15）的探针部件（11），远侧末端的管状部分的远端中的穿透远侧末端（16）和组织接收孔（17），以及组织切割构件（20），其可滑动地设置在所述探针构件内，以通过对所述组织切割构件的内腔施加真空来切割通过所述孔被拉入所述装置的内部的组织样本。该装置还具有驱动器部件（12），探针部件可释放地固定到该部件上。驱动器具有用于调节管状部分的取向并因此调节其中的孔的驱动构件（22,23）和一个或多个驱动构件（30），用于移动管状区段内的组织切割构件以从组织切断组织样本通过孔延伸到管状部分的内部。赋予组织切割器的运动至少是纵向的，并且优选地也是振动和/或旋转以有效地将组织样本与延伸穿过管状部分中的孔的组织分离。

3. 发明申请

WO2008063638A3 MRI DETECTABLE OBTURATOR 审中-公开
标题翻译： MRI检测器
公开(公告)号：WO2008063638A3
公开(公告)日：2008-09-18
申请号：PCT/US2007024255
申请日：2007-11-20
申请人： SENORX INC , LUBOCK PAUL , JONES MICHAEL L , BROADAWAY ETHAN , LOUW FRANK R
发明人： LUBOCK PAUL , JONES MICHAEL L , BROADAWAY ETHAN , LOUW FRANK R
IPC分类号： A61B17/34 , A61B17/00 , A61B19/00
CPC分类号： A61B17/32 , A61B17/3417 , A61B17/3431 , A61B17/3468 , A61B17/3496 , A61B17/3498 , A61B90/39 , A61B2017/00477 , A61B2017/00911 , A61B2090/062 , A61B2090/3908 , A61B2090/3954 , A61B2090/3987
摘要： An obturator (10) with an elongated shaft (11), a proximal end
摘要翻译：具有细长轴（11），近端<12），基本上封闭的远端（14）和MRI可检测的远端轴部分（15）的闭塞器（10），其不干扰组织的磁共振成像于此。优选地，远侧轴部分具有有效的MRI检测质量，以便在磁共振成像时在远侧轴部分的轮廓内提供清晰的，Tl加权的图像。

4. 发明申请

WO2008008089A3 ASYMMETRICAL IRRADIATION OF A BODY CAVITY 审中-公开
标题翻译：身体不对称辐射
公开(公告)号：WO2008008089A3
公开(公告)日：2008-03-06
申请号：PCT/US2006044067
申请日：2006-11-13
申请人： SENORX INC , LUBOCK PAUL , JONES MICHAEL L , LOUW FRANK R
发明人： LUBOCK PAUL , JONES MICHAEL L , LOUW FRANK R
IPC分类号： A61N5/10 , A61M36/04
CPC分类号： A61N5/1014 , A61N5/1002 , A61N5/1015 , A61N2005/1003 , A61N2005/1004 , A61N2005/1005 , A61N2005/1018 , A61N2005/1024
摘要： The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.
摘要翻译：本公开描述了用于在体腔或部位的不对称照射的装置和方法，例如在去除组织之后，例如，活检或癌症。一个装置包括从纵向轴线偏移或不可固定的内腔，以增加围绕体腔的第一组织部分从辐射源接收的辐射的强度，并且减少或最小化由第二组织部分接收的辐射（例如健康组织）。

5. 发明申请

WO2009058186A2 SOFT BODY CATHETER WITH LOW FRICTION LUMEN 审中-公开
标题翻译：柔软的身体导管与低摩擦的温度
公开(公告)号：WO2009058186A2
公开(公告)日：2009-05-07
申请号：PCT/US2008011435
申请日：2008-10-03
申请人： SENORX INC , JONES MICHAEL L , LOUW FRANK R
发明人： JONES MICHAEL L , LOUW FRANK R
IPC分类号： A61L29/06 , A61L29/14
CPC分类号： A61L29/18 , A61L29/06 , A61L29/085 , A61L29/14 , A61L2420/06 , C08L75/04
摘要： The disclosure is directed to radiation catheter devices, methods for controlled application of irradiation to tissue at a body site, such as a cavity formed after removal of tissue, e.g. cancer, using such radiation catheter devices, solutions for forming a more lubricious luminal surface and method for lining lumens of such devices to improve the frictional characteristics thereof. The catheter device includes a flexible elongated shaft which is formed of low durometer polymeric material, which can be readily folded or coiled for securing the shaft to or under the skin of the patient and a radiation lumen lined with high durometer polymeric material and finely divided particulate to improve the frictional characteristics. The elongated shaft has at least one inner lumen for receiving a radiation source which has a layer of high durometer polymeric material that provides lower surface friction to facilitate advancement of a radiation source therein.
摘要翻译：本公开涉及辐射导管装置，用于受控地应用照射到身体部位的组织的方法，例如在去除组织后形成的空腔，例如，癌症，使用这种辐射导管装置，用于形成更加光滑的腔表面的解决方案和用于衬里这些装置的流明以提高其摩擦特性的方法。导管装置包括柔性细长轴，其由低硬度聚合物材料形成，其可以容易地折叠或卷绕以将轴固定到患者的皮肤上或皮下，并且内衬有高硬度聚合物材料和细碎颗粒以提高摩擦特性。细长轴具有用于接收辐射源的至少一个内腔，辐射源具有提供较低表面摩擦以便促进其中的辐射源的高硬度聚合材料层。

6. 发明申请

WO2004075719A3 BIOPSY DEVICE WITH INNER CUTTING MEMBER 审中-公开
标题翻译：具有内切刀的生物装置
公开(公告)号：WO2004075719A3
公开(公告)日：2007-03-01
申请号：PCT/US2004005023
申请日：2004-02-20
申请人： SENORX INC
发明人： QUICK RICHARD L , LOUW FRANK R , LUBOCK PAUL , SHABAZ MARTIN V , SAFABASH JASON
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B17/32 , A61B17/34
CPC分类号： A61B10/0275 , A61B17/32002 , A61B17/3417 , A61B2010/0208 , A61B2010/0225 , A61B2017/0046 , A61B2017/00473 , A61B2017/3405 , A61B2017/3454 , A61B2090/0811
摘要： The invention is directed to devices and methods for separating and collecting a tissue specimen form a patient's target site. The device includes a probe member and a penetrating distal tip and a tissue receiving aperture, and a tissue cutting member which is rotatable disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture. The longitudinal edges of the aperture are preferably sharpened to engage the cutting edges of the tissue cutting member. Vacuum may be provided in the inner lumen of the cutting member to transport the tissue therethrough. Rotation, rotational oscillation and/or longitudinal reciprocation of the tissue cutting member is effective to separate a tissue specimen from surrounding tissue. An accessing cannula having a tissue receiving aperture may be concentrically disposed within the probe member and about the tissue cutting member.
摘要翻译：本发明涉及用于从患者的目标部位分离和收集组织标本的装置和方法。该装置包括探针构件和穿透远侧末端和组织接收孔，以及组织切割构件，其可旋转地设置在探针构件内，以通过孔切割被拉入装置内部的组织样本。孔的纵向边缘优选地被锐化以接合组织切割构件的切割边缘。可以在切割构件的内腔中设置真空以将组织输送通过其中。组织切割构件的旋转，旋转振动和/或纵向往复运动有效地将组织标本与周围组织分开。具有组织接收孔的进入套管可以同心地设置在探针构件内并且围绕组织切割构件。

7. 发明专利

CA2617582C BIOPSY DEVICE WITH FLUID DELIVERY TO TISSUE SPECIMENS 未知
公开(公告)号：CA2617582C
公开(公告)日：2016-09-13
申请号：CA2617582
申请日：2006-08-04
申请人： SENORX INC
发明人： QUICK RICHARD L , SHABAZ MARTIN V , LOUW FRANK R , LUBOCK PAUL , SAFABASH JASON H
IPC分类号： A61B10/02 , A61B17/00 , A61B17/32
摘要： The invention is directed to a system and method for separating and collecting one or more tissue specimens from a target site within a patient and flushing the specimen to remove blood, debris and the like before the specimen is removed from the biopsy device. The flow of flushing fluid to the tissue collector is preferably controlled to coincide with delivery of one or more specimens to the collecting tray or basket of the device or after the receipt of the specimen within the tissue collector to ensure that the fluid (16) is applied to a fresh specimen. The tissue tray or basket within the tissue collector (14) has an open or foraminous portion to facilitate removal of fluid, such as the applied fluid and blood, and other debris from the tissue specimens on the tray. Vacuum (22) is provided within the tissue collector, preferably under the tray to remove fluid and debris from the collector interior.

8. 发明专利

ES2557586T3 Dispositivo de biopsia con orientación seleccionable de la abertura de recepción de tejidos e iluminación del sitio 未知
公开(公告)号：ES2557586T3
公开(公告)日：2016-01-27
申请号：ES11184498
申请日：2005-07-29
申请人： SENORX INC
发明人： SHABAZ MARTIN V , QUICK RICHARD L , LOUW FRANK R , LUBOCK PAUL , SAFABASH JASON H
IPC分类号： A61B10/02 , A61B10/00 , A61B17/00 , A61B17/32 , A61B17/34
摘要： Un componente (12) de accionamiento para un sistema de biopsia de tejido para acceder a y recoger una o más muestras de tejido de un sitio objetivo de un paciente, incluyendo el sistema de biopsia de tejido un componente de sonda alargado desechable, estando el componente de accionamiento configurado para recibir en una relación operativa una porción proximal del componente de sonda, en el que el componente de accionamiento presenta un primer motor de accionamiento configurado para hacer rotar una sección tubular del componente de sonda para orientar una abertura de recepción de tejido en el extremo distal de una sección tubular y un segundo motor de accionamiento configurado para accionar un miembro de corte de tejido longitudinalmente dentro de la sección tubular para cortar el tejido que se extiende por dentro de la sección tubular a través de su abertura de recepción de tejido, caracterizado porque el componente de accionamiento presenta al menos un elemento (66, 67) de iluminación en una porción distal del mismo.

9. 发明专利

ES2557584T3 Componente de accionamiento con elemento de iluminación en la porción distal del mismo 未知
公开(公告)号：ES2557584T3
公开(公告)日：2016-01-27
申请号：ES11175597
申请日：2004-12-20
申请人： SENORX INC
发明人： SHABAZ MARTIN V , QUICK RICHARD L , LOUW FRANK R , LUBOCK PAUL , SAFABASH JASON H
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B17/32 , A61B17/34 , A61B19/00
摘要： Un dispositivo para acceder y recoger tejido de un sitio diana en el interior de un paciente, que comprende: a. una sonda alargada (11) que tiene un eje longitudinal, que tiene un extremo proximal configurado para ser asegurado a un accionamiento, que tiene un lumen interior que se extiende en su interior, que tiene un extremo distal y que tiene una abertura (17) proximal al extremo distal configurada para recibir el tejido desde el sitio diana; y b. una punta de penetración (16) en el tejido en el extremo distal que tiene i. una base proximal (70) asegurada al extremo distal de la sonda alargada, ii. una punta afilada distal (71), que es distal a una base proximal, el dispositivo se caracteriza porque la citada punta de penetración en el tejido tiene iii. una primera superficie cóncava (72) que tiene una línea central que se extiende desde la base hasta la punta distal afilada, iv. una segunda superficie cóncava (73) que tiene una línea central que se extiende desde la base hasta la punta distal afilada y que intersecta la primera superficie cóncava formando con la misma un primer filo de corte curvado (75) que conduce a la punta distal afilada, y v. una tercera superficie cóncava (74) que tiene una línea central que se extiende desde la base hasta la punta distal afilada y que intersecta la primera superficie cóncava formando con la misma un segundo filo de corte curvado (77) que conduce hasta el punta distal afilado y que intersecta la segunda superficie cóncava formando con la misma un tercer filo de corte curvado (76) que conduce hasta la punta distal afilada; y un medio de corte de tejido que está dispuesto dentro del miembro de sonda alargada y que está configurado para cortar un espécimen de tejido a partir de tejido que se extiende dentro de la abertura de recepción de tejido de la sonda alargada de corte.

10. 发明专利

CA2516663C BIOPSY DEVICE WITH INNER CUTTING MEMBER 未知
公开(公告)号：CA2516663C
公开(公告)日：2012-09-18
申请号：CA2516663
申请日：2004-02-20
申请人： SENORX INC
发明人： QUICK RICHARD L , LOUW FRANK R , LUBOCK PAUL , SHABAZ MARTIN V , SAFABASH JASON
IPC分类号： A61B10/02 , A61B10/00 , A61B17/00 , A61B17/32 , A61B17/34
摘要： The invention is directed to devices and methods for separating and collecting a tissue specimen from a patient~s target site. The device includes a probe member with a penetrating distal tip and a tissue receiving aperture, and a tissue cutting member which is rotatable disposed within the prove member to cut a tissue specimen drawn into the interior of the device through the aperture. The longitudinal edges of the aperture are preferably sharpened to engage the cutting edges of the tissue cutting member. Vacuum may be provided in the inner lumen of the cutting member to transport tissue therethrough. Rotation, rotational oscillation and/or longitudinal reciprocation of the tissue cutting member is effective to separate a tissue specimen from surrounding tissue. An accessing cannula having an tissue receiving aperture may be concentrically disposed within the probe member and about the tissue cutting member. The tissue cutting edge of the tissue cutting member preferably is longitudinally oriented and may have a cutting angle less than 90~ with respect to the longitudinal axis of the tissue cutting member.

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