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1. 发明申请

WO2005087731A8 SULFUR COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE 审中-公开
标题翻译：作为乙型肝炎病毒NS3丝氨酸蛋白酶抑制剂的硫化合物
公开(公告)号：WO2005087731A8
公开(公告)日：2006-06-22
申请号：PCT/US2005005795
申请日：2005-02-24
申请人： SCHERING CORP , BENNETT FRANK , LOVEY RAYMOND G , HUANG YUHUA , HENDRATA SISKA , SAKSENA ANIL K , BOGEN STEPHANE L , LIU YI-TSUNG , NJOROGE F GEORGE , VENKATRAMAN SRIKANTH , CHEN KEVIN X , SANNIGRAHI MOUSUMI , ARASAPPAN ASHOK , GIRIJAVALLABHAN VIYYOOR M , VELAZQUEZ FRANCISCO , NAIR LATHA
发明人： BENNETT FRANK , LOVEY RAYMOND G , HUANG YUHUA , HENDRATA SISKA , SAKSENA ANIL K , BOGEN STEPHANE L , LIU YI-TSUNG , NJOROGE F GEORGE , VENKATRAMAN SRIKANTH , CHEN KEVIN X , SANNIGRAHI MOUSUMI , ARASAPPAN ASHOK , GIRIJAVALLABHAN VIYYOOR M , VELAZQUEZ FRANCISCO , NAIR LATHA
IPC分类号： C07D209/52 , C07D209/56 , C07D491/04 , C07K5/08 , C07K7/02
CPC分类号： C07D209/52 , A61K38/00 , C07D207/16 , C07D209/56 , C07D405/12 , C07D409/12 , C07D411/12 , C07D491/04 , C07K5/0202
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
摘要翻译：本发明公开了具有HCV蛋白酶抑制活性的新型化合物及其制备方法。在另一个实施方案中，本发明公开了包含这些化合物的药物组合物以及使用它们来治疗与HCV蛋白酶相关的病症的方法。

2. 发明公开

EP2781420A4 QUICK BRAKING ASSEMBLY 审中-公开
标题翻译： FAST制动系统
公开(公告)号：EP2781420A4
公开(公告)日：2016-06-29
申请号：EP12849320
申请日：2012-07-27
申请人： LI ZHONGHUA , HUANG YUHUA
发明人： LI ZHONGHUA , HUANG YUHUA
IPC分类号： B60T13/02 , B60T1/08 , B60T1/14 , B60T1/16 , B61C15/10 , B61H7/00 , B61H7/06 , B62L1/00 , B64C25/32 , E01H8/10
CPC分类号： B61H11/14 , B60T1/14 , B60T1/16 , B61H7/06 , B62L1/00 , E01H8/10

3. 发明申请

WO2013071686A3 QUICK BRAKING ASSEMBLY 审中-公开
标题翻译：快速制动总成
公开(公告)号：WO2013071686A3
公开(公告)日：2013-07-04
申请号：PCT/CN2012001011
申请日：2012-07-27
申请人： LI ZHONGHUA , HUANG YUHUA
发明人： LI ZHONGHUA , HUANG YUHUA
IPC分类号： B60T13/02 , B60T1/08 , B61H7/00 , B64C25/32
CPC分类号： B61H11/14 , B60T1/14 , B60T1/16 , B61H7/06 , B62L1/00 , E01H8/10
摘要： The present invention relates to the technical field of vehicle braking of high speed trains, high speed automobiles, high speed aircraft, high speed motorcycles and the like. Disclosed is a quick braking assembly. In order to overcome the defect of deficient braking capability of vehicles such as high speed trains, high speed automobiles, high speed aircraft, high speed motorcycles and the like, a braking track device is designed to be installed at proper positions at the bottom of a high speed train and a high speed automobile. Adopted are a specialized braking material and a serrated occlusal surface, and a windscreen braking device designed to be installed at the tail and two wings of a high speed train and a high speed automobile. A pressure spray gun with braking material is installed underneath a vehicle. Also adopted are a specialized braking material and a serrated occlusal surface, and a braking track device designed to be installed underneath the body of a high speed aircraft. A windscreen brake device is designed to be installed at the tail of a motorcycle.
摘要翻译：本发明涉及高速列车，高速汽车，高速飞机，高速摩托车等的车辆制动技术领域。公开了一种快速制动组件。为了克服高速列车，高速汽车，高速飞机，高速摩托车等车辆制动能力不足的缺陷，制动轨道装置被设计成安装在底部的适当位置高速列车和高速汽车。采用专门的制动材料和锯齿状咬合面，以及设计用于安装在高速列车和高速汽车的尾翼和两翼的挡风玻璃制动装置。具有制动材料的压力喷枪安装在车辆下方。还采用专门的制动材料和锯齿状咬合面，以及设计成安装在高速飞机身体下方的制动轨道装置。挡风玻璃制动装置被设计成安装在摩托车尾部。

4. 发明专利

JP2009051860A New peptide as ns3-serine protease inhibitor of hepatitis c virus 审中-公开
标题翻译：新型肽作为丙型肝炎病毒的NS3-丝氨酸蛋白酶抑制剂
公开(公告)号：JP2009051860A
公开(公告)日：2009-03-12
申请号：JP2008275159
申请日：2008-10-27
申请人： Dendreon Corp , Schering Corp , シェーリングコーポレイションSchering Corporation , デンドレオンコーポレイション
发明人： SAKSENA ANIL K , GIRIJAVALLABHAN VIYYOOR MOOPIL , LOVEY RAYMOND G , JAO EDWIN E , BENNETT FRANK , MCCORMICK JINPING L , WANG HAIYAN , PIKE RUSSELL E , BOGEN STEPHANE L , CHAN TIN-YAU , LIU YI-TSUNG , ZHU ZHAONING , NJOROGE F GEORGE , ARASAPPAN ASHOK , PAREKH TEJAL N , GANGULY ASHIT K , CHEN KEVIN X , VENKATRAMAN SRIKANTH , VACCARO HENRY A , PINTO PATRICK A , SANTHANAM BAMA , WU WANLI , SISKA HENDRATA , HUANG YUHUA , SCOTT JEFFREY KEMP , ODILE ESTHER LEVY , LIM-WILBY MARGUERITA , TAMURA SUSAN Y
IPC分类号： A61K45/00 , C07K14/81 , A61K31/7052 , A61K31/7056 , A61K38/00 , A61K38/21 , A61K38/55 , A61P1/16 , A61P31/12 , A61P31/14 , A61P43/00 , C07K5/02 , C07K5/062 , C07K5/065 , C07K5/08 , C07K5/087 , C07K7/02
CPC分类号： C07K5/0202 , A61K38/00 , C07K5/0812 , C07K5/0827 , C07K7/02
摘要： PROBLEM TO BE SOLVED: To provide a novel hepatitis C virus (HCV) protease inhibitor, a pharmaceutical composition comprising at least one such inhibitor, a production method of the inhibitor and a method of using the inhibitor for treating hepatitis C and disorders associated therewith. SOLUTION: A new peptide compound is useful as an HCV NS3/NS4a serine protease inhibitor. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：待解决的问题：提供一种新型丙型肝炎病毒（HCV）蛋白酶抑制剂，包含至少一种这样的抑制剂的药物组合物，抑制剂的制备方法和使用该抑制剂治疗丙型肝炎和病症的方法相关联。解决方案：新的肽化合物可用作HCV NS3 / NS4a丝氨酸蛋白酶抑制剂。版权所有（C）2009，JPO＆INPIT

5. 发明专利

CY1111212T1 ΘΕΙΙΚΕΣ ΕΝΩΣΕΙΣ ΩΣ ΑΝΑΣΤΟΛΕΙΣ ΤΗΣ ΠΡΩΤΕΑΣΗΣ ΣΕΡΙΝΗΣ NS3 ΤΟΥ ΙΟΥ ΤΗΣ ΗΠΑΤΙΤΙΔΑΣ Γ 未知
公开(公告)号：CY1111212T1
公开(公告)日：2015-06-11
申请号：CY101100796
申请日：2010-09-01
申请人： SCHERING CORP
发明人： BENNETT FRANK , LOVEY RAYMOND G , HUANG YUHUA , HENDRATA SISKA , SAKSENA ANIL K , BOGEN STEPHANE L , LIU YI-TSUNG , NJOROGE F GEORGE , VENKATRAMAN SRIKANTH , CHEN KEVIN X , SANNIGRAHI MOUSUMI , ARASAPPAN ASHOK , GIRIJAVALLABHAN VIYYOOR M , VELAZQUEZ FRANCISCO , NAIR LATHA
IPC分类号： C07D209/52 , A61K31/403 , A61K31/407 , A61P31/12 , C07D209/56 , C07D491/04 , C07K5/02 , C07K5/08 , C07K7/02
摘要： Ηπαρούσαεφεύρεσηαποκαλύπτεινέεςενώσειςοιοποίεςέχουνανασταλτικήδραστηριότητατηςπρωτεάσηςτου HCV καθώςεπίσηςμεθόδουςγιατηνΠαρασκευήτέτοιωνενώσεων. Σεμιαάλληπραγματοποίηση, ηεφεύρεσηαποκαλύπτειφαρμακευτικέςσυνθέσειςπουπεριλαμβάνουντέτοιεςενώσειςκαθώςεπίσηςμεθόδουςχρήσηςτουςγιαθεραπείαδιαταραχώνπουσχετίζονταιμετηνπρωτεάσητου HCV.

6. 发明专利

CA2557495C SULFUR COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE 未知
公开(公告)号：CA2557495C
公开(公告)日：2014-04-15
申请号：CA2557495
申请日：2005-02-24
申请人： SCHERING CORP
发明人： BENNETT FRANK , LOVEY RAYMOND G , HUANG YUHUA , HENDRATA SISKA , SAKSENA ANIL K , BOGEN STEPHANE L , LIU YI-TSUNG , NJOROGE F GEORGE , VENKATRAMAN SRIKANTH , CHEN KEVIN X , SANNIGRAHI MOUSUMI , ARASAPPAN ASHOK , GIRIJAVALLABHAN VIYYOOR M , VELAZQUEZ FRANCISCO , NAIR LATHA
IPC分类号： C07D209/52 , C07D209/56 , C07D491/04 , C07K5/08 , C07K7/02
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

7. 发明专利

AT470660T 未知
公开(公告)号：AT470660T
公开(公告)日：2010-06-15
申请号：AT05723607
申请日：2005-02-24
申请人： SCHERING CORP
发明人： BENNETT FRANK , LOVEY RAYMOND G , HUANG YUHUA , HENDRATA SISKA , SAKSENA ANIL , BOGEN STEPHANE , LIU YI-TSUNG , NJOROGE F , VENKATRAMAN SRIKANTH , CHEN KEVIN , SANNIGRAHI MOUSUMI , ARASAPPAN ASHOK , GIRIJAVALLABHAN VIYYOOR , VELAZQUEZ FRANCISCO , NAIR LATHA
IPC分类号： C07D209/52 , A61K31/403 , A61K31/407 , A61P31/12 , C07D209/56 , C07D491/04 , C07K5/02 , C07K5/08 , C07K7/02
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

8. 发明专利

AT469914T 未知
公开(公告)号：AT469914T
公开(公告)日：2010-06-15
申请号：AT03731956
申请日：2003-01-16
申请人： SCHERING CORP , DENDREON CORP
发明人： SAKSENA ANIL , GIRIJAVALLABHN VIYYOOR , LOVEY RAYMOND , JAO EDWIN , BENNETT FRANK , MC CORMICK JINPING , WANG HAIYAN , PIKE RUSSELL , BOGEN STEPHANE , CHAN TIN-YAU , LIU YI-TSUNG , ZHU ZHAONING , NJOROGE GEORGE , ARASAPPAN ASHOK , PAREKH TEJAL , GANGULY ASHIT , CHEN KEVIN , VENKATRAMAN SRIKANTH , VACCARO HENRY , PINTO PATRICK A , SANTHANAM BAMA , KEMP SCOTT JEFFREY , LEVY ODILE ESTHER , LIM-WILBY MARGUERITA , TAMURA SUSAN Y , WU WANLI , HENDRATA SISKA , HUANG YUHUA , WONG JESSE K , NAIR LATHA G
IPC分类号： C07K5/062 , C12N9/99 , A61K31/70 , A61K38/00 , A61K38/21 , A61K38/55 , A61P1/16 , A61P31/14 , A61P43/00 , C07K5/02 , C07K5/023 , C07K5/065 , C07K7/02
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

9. 发明专利

HK1095819A1 SULFUR COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE 未知
公开(公告)号：HK1095819A1
公开(公告)日：2007-07-27
申请号：HK07102951
申请日：2007-03-19
申请人： SCHERING CORP
发明人： BENNETT FRANK , LOVEY RAYMOND G , HUANG YUHUA , HENDRATA SISKA , SAKSENA ANIL K , BOGEN STEPHANE L , LIU YI-TSUNG , NJOROGE F GEORGE , VENKATRAMAN SRIKANTH , CHEN KEVIN X , SANNIGRAHI MOUSUMI , ARASAPPAN ASHOK , GIRIJAVALLABHAN VIYYOOR M , VELAZQUEZ FRANCISCO , NAIR LATHA
IPC分类号： A61K20060101 , A61P20060101 , C07D20060101 , C07D209/52 , C07D209/56 , C07D491/04 , C07K20060101 , C07K5/08 , C07K7/02
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

10. 发明专利

NO20064358L 未知
公开(公告)号：NO20064358L
公开(公告)日：2006-11-24
申请号：NO20064358
申请日：2006-09-26
申请人： SCHERING CORP
发明人： GIRIJAVALLABHAN VIYYOOR MOOPIL , SAKSENA ANIL K , LIU YI-TSUNG , NJOROGE F GEORGE , BOGEN STEPHANE L , HUANG YUHUA , CHEN KEVIN X , HENDRATA SISKA , NAIR LATHA G , VENKATRAMAN SRIKANTH , SANNIGRAHI MOUSUMI , ARASAPPAN ASHOK , BENNETT FRANK , LOVEY RAYMOND , VELAZQUEZ FRANCISCO
IPC分类号： C07D209/52 , A61K31/403 , A61P31/14 , C07D209/56 , C07D409/04 , C07D491/04 , C07K5/08 , C07K7/02
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

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