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1. 发明申请

WO2007097983A3 SYSTEMS AND METHODS FOR DELIVERING A MEDICAL IMPLANT 审中-公开
标题翻译：用于输送医疗植入物的系统和方法
公开(公告)号：WO2007097983A3
公开(公告)日：2008-03-06
申请号：PCT/US2007003992
申请日：2007-02-14
申请人： SADRA MEDICAL INC , SALAHIEH AMR , DUERI JEAN-PIERRE , VALENCIA HANS F , HILDEBRAND DANIEL , BRANDT BRIAN D , MOREJOHN DWIGHT P , ARGENTO CLAUDIO , SAUL TOM , HAUG ULRICH R
发明人： SALAHIEH AMR , DUERI JEAN-PIERRE , VALENCIA HANS F , HILDEBRAND DANIEL , BRANDT BRIAN D , MOREJOHN DWIGHT P , ARGENTO CLAUDIO , SAUL TOM , HAUG ULRICH R
IPC分类号： A61F2/24 , A61F2/90
CPC分类号： A61F2/2427 , A61B17/0644 , A61B17/068 , A61B17/221 , A61B2017/22035 , A61B2017/2215 , A61F2/2409 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2/90 , A61F2002/9534 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0078 , A61F2230/008 , A61F2250/001
摘要： The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system.
摘要翻译：本发明涉及用于在患者的天然心脏瓣膜内和/或穿过患者的天然心脏瓣膜内血管内递送和释放假体（例如主动脉假体）的装置和方法，以下称为替换患者的心脏瓣膜。在一些实施例中，递送系统包括多个第一致动元件，其适于以第一构造接合多个第二元件以在输送系统内捕获植入物，并且其中多个第一可致动元件适于接合多个第二可动元件元件处于第二配置并且从输送系统释放植入物。

2. 发明申请

WO2007053243A2 METHODS AND APPARATUS FOR ENDOVASCULAR HEART VALVE REPLACEMENT COMPRISING TISSUE GRASPING ELEMENTS 审中-公开
标题翻译：用于包裹组织成像元件的内部心脏瓣膜替换的方法和装置
公开(公告)号：WO2007053243A2
公开(公告)日：2007-05-10
申请号：PCT/US2006036286
申请日：2006-09-18
申请人： SADRA MEDICAL INC , SALAHIEH AMR , HILDEBRAND DANIEL , SAUL TOM
发明人： SALAHIEH AMR , HILDEBRAND DANIEL , SAUL TOM
IPC分类号： A61F2/24 , A61F2/90
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2439 , A61F2/848 , A61F2/90 , A61F2220/0016 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0078
摘要： The present invention provides an apparatus for endovascularly replacing a patient's heart valve. In some embodiments, the apparatus includes an expandable anchor supporting a replacement valve, the anchor and replacement valve being adapted for percutaneous delivery and deployment to replace the patient's heart valve, the anchor having a braid having atraumatic grasping elements adapted to grasp tissue in a vicinity of the patient's heart valve.
摘要翻译：本发明提供一种用于血管内替换患者心脏瓣膜的装置。在一些实施例中，该装置包括支撑更换瓣膜的可膨胀锚固件，所述锚固件和替换阀适用于经皮输送和展开以替换患者的心脏瓣膜，所述锚具具有编织物，所述编织物具有适合于抓住附近的组织的无创伤的抓握元件的病人的心脏瓣膜。

3. 发明申请

WO2007035471A2 MEDICAL DEVICE DELIVERY SHEATH 审中-公开
标题翻译：医疗器械输送管
公开(公告)号：WO2007035471A2
公开(公告)日：2007-03-29
申请号：PCT/US2006036001
申请日：2006-09-14
申请人： SADRA MEDICAL INC , SALAHIEH AMR , LEUNG EMMA , HILDEBRAND DANIEL , LEPAK JONAH , HAUG ULRICH R , MOREJOHN DWIGHT P , SAUL TOM
发明人： SALAHIEH AMR , LEUNG EMMA , HILDEBRAND DANIEL , LEPAK JONAH , HAUG ULRICH R , MOREJOHN DWIGHT P , SAUL TOM
IPC分类号： A61M25/09
CPC分类号： A61M25/0662 , A61F2/2436 , A61F2002/9528 , A61F2002/9534 , A61M25/0045 , A61M25/0051 , A61M25/0053 , A61M25/0054 , A61M25/0074 , A61M25/008 , A61M25/0138
摘要： A support member for a catheter sheath is disclosed. The support member has a series of ribs with a distal member having integrated fingers for providing radial compliance. The support member provides sufficient axial stiffness to provide a desired pushability of a minimally invasive device for replacing a heart valve. Various alternative embodiments are also described.
摘要翻译：公开了用于导管护套的支撑构件。支撑构件具有一系列肋，其具有具有用于提供径向顺应性的集成指状物的远端构件。支撑构件提供足够的轴向刚度以提供用于更换心脏瓣膜的微创装置的期望推进性。还描述了各种替代实施例。

4. 发明申请

WO2007058847A3 MEDICAL IMPLANT DEPLOYMENT TOOL 审中-公开
标题翻译：医用植物部署工具
公开(公告)号：WO2007058847A3
公开(公告)日：2009-04-30
申请号：PCT/US2006043484
申请日：2006-11-08
申请人： SADRA MEDICAL INC , SALAHIEH AMR , HAUG ULRICH R , ARGENTO CLAUDIO , MOREJOHN DWIGHT , HILDEBRAND DANIEL , SAUL TOM
发明人： SALAHIEH AMR , HAUG ULRICH R , ARGENTO CLAUDIO , MOREJOHN DWIGHT , HILDEBRAND DANIEL , SAUL TOM
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2439 , A61F2002/9517 , A61F2230/0054 , A61M25/0136 , A61M25/0144 , A61M25/0147
摘要： A medical implant deployment tool and deployment method are disclosed. One aspect of the invention provides an implant system including an implant adapted for endovascular delivery and deployment; and a deployment tool adapted to deploy the implant, with the deployment tool having an actuation controller; a pluralit of actuation elements adapted to apply forces to one or more implant deployment mechanisms and each adapted to extend along an actuation element path within a patient's vasculature; and an actuation element compensation mechanism adapted to compensate for differences in length between the actuation element paths. Another aspect the invention provides a method of deploying an implant including the steps of endovascularly delivering an impla and implant deployment mechanisms to an implant site and applying an actuation force to the implant deployment mechanisms through actuation elements extending through the patient's vasculature while compensating for differences in length between actuation element path lengths to deploy the implant.
摘要翻译：公开了一种医用植入物部署工具和部署方法。本发明的一个方面提供一种植入系统，其包括适于血管内递送和展开的植入物; 以及适于部署所述植入物的展开工具，所述展开工具具有致动控制器; 多个致动元件，其适于将力施加到一个或多个植入物展开机构，并且每个适于沿着患者的脉管系统内的致动元件路径延伸; 以及致动元件补偿机构，其适于补偿致动元件路径之间的长度差异。本发明的另一方面提供了一种部署植入物的方法，包括以下步骤：血管内递送植入物和植入部署机构到植入部位，并且通过延伸穿过患者脉管系统的致动元件向植入物展开机构施加致动力，同时补偿致动元件路径长度以部署植入物之间的长度。

5. 发明申请

WO2007033093A3 TWO-PART PACKAGE FOR MEDICAL IMPLANT 审中-公开
标题翻译：医疗植物的两部分包装
公开(公告)号：WO2007033093A3
公开(公告)日：2008-01-17
申请号：PCT/US2006035345
申请日：2006-09-11
申请人： SADRA MEDICAL INC , SALAHIEH AMR , SAUL TOM , GESHLIDER ROBERT , JOHNSON ANDREA , MOREJOHN DWIGHT , HILDEBRAND DANIEL , DUERI JEAN-PAUL
发明人： SALAHIEH AMR , SAUL TOM , GESHLIDER ROBERT , JOHNSON ANDREA , MOREJOHN DWIGHT , HILDEBRAND DANIEL , DUERI JEAN-PAUL
IPC分类号： A61F2/06
CPC分类号： B65D25/04 , A61F2/0095 , A61F2/2427 , A61F2002/9517 , B65B5/04 , B65B55/16 , B65D41/04 , B65D81/22
摘要： The invention provides a two-part package and method of use for a pre-attached medical implant and delivery tool system. The package includes a wet compartment and a dry compartment and allows a pre-attached implant and delivery tool system to be at least partially stored immersed in a fluid in the wet compartment and at least partially stored in the dry compartment. In one embodiment the implant comprises a replacement heart valve, and the heart valve is stored inside the wet compartment while the heart valve delivery tool remains dry in the dry compartment.
摘要翻译：本发明提供了用于预附接的医疗植入物和递送工具系统的两部分包装和使用方法。该包装包括湿室和干燥室，并且允许将预先附着的植入物和递送工具系统至少部分地储存在浸入湿室中的流体中并且至少部分储存在干燥室中。在一个实施例中，植入物包括置换心脏瓣膜，并且心脏瓣膜储存在湿室内，而心脏瓣膜递送工具在干燥室中保持干燥。

6. 发明申请

WO2007044285A2 METHODS AND APPARATUS FOR PERFORMING VALVULOPLASTY 审中-公开
标题翻译：用于实施戊型肝炎的方法和装置
公开(公告)号：WO2007044285A2
公开(公告)日：2007-04-19
申请号：PCT/US2006038352
申请日：2006-10-02
申请人： SADRA MEDICAL INC , SALAHIEH AMR , MOREJOHN DWIGHT P , HILDEBRAND DANIEL , SAUL TOM
发明人： SALAHIEH AMR , MOREJOHN DWIGHT P , HILDEBRAND DANIEL , SAUL TOM
IPC分类号： A61M29/00
CPC分类号： A61F2/2418 , A61B2017/00783 , A61F2/2412 , A61F2/2439 , A61F2002/9517 , A61F2250/0097
摘要： The present invention relates to apparatus and methods for performing valvuloplasty. In some embodiments, the apparatus includes an expandable braid valvuloplasty device. In some embodiments, the method and apparatus may be used as an adjunct to percutaneous heart valve replacement. In some embodiments, the apparatus and methods may provide a medical practitioner with feedback, monitoring or measurement information, e.g., information relevant to percutaneous transcatheter heart valve replacement.
摘要翻译：本发明涉及进行瓣膜成形术的装置和方法。在一些实施例中，该装置包括可扩张的编织瓣膜成形术装置。在一些实施例中，该方法和装置可以用作经皮心脏瓣膜置换的辅助装置。在一些实施例中，该装置和方法可以向医务人员提供反馈，监测或测量信息，例如与经皮经导管心脏瓣膜置换相关的信息。

7. 发明申请

WO2010042950A3 MEDICAL DEVICES AND DELIVERY SYSTEMS FOR DELIVERING MEDICAL DEVICES 审中-公开
标题翻译：用于输送医疗设备的医疗设备和输送系统
公开(公告)号：WO2010042950A3
公开(公告)日：2010-07-15
申请号：PCT/US2009060531
申请日：2009-10-13
申请人： SADRA MEDICAL INC , PAUL DAVID , SUTTON BENJAMIN , MCCOLLUM BRIAN , BRANDT BRIAN D , LEUNG EMMA , MARTIN KENNETH M , SALAHIEH AMR , HILDEBRAND DANIEL
发明人： PAUL DAVID , SUTTON BENJAMIN , MCCOLLUM BRIAN , BRANDT BRIAN D , LEUNG EMMA , MARTIN KENNETH M , SALAHIEH AMR , HILDEBRAND DANIEL
IPC分类号： A61M25/088 , A61F2/90 , A61M25/04
CPC分类号： A61F2/2427 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2/90 , A61F2/95 , A61F2/954 , A61F2/962 , A61F2/966 , A61F2/97 , A61F2002/9517 , A61F2002/9528 , A61F2002/9534 , A61F2220/0041 , A61F2220/0075 , A61F2230/0067 , A61F2250/006
摘要： Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system.
摘要翻译：用于将医疗设备输送到受试者内的目标位置的医疗设备和输送系统。在一些实施例中，医疗设备可以被锁定在完全展开和锁定的配置中。在一些实施例中，递送系统配置有单个致动器以控制递送系统的多个部件的移动。在一些实施例中，致动器控制输送系统的多个部件的独立且相关的运动。

8. 发明专利

JP2012005846A Repositionable heart valve 有权
标题翻译：可重复使用的心脏瓣膜
公开(公告)号：JP2012005846A
公开(公告)日：2012-01-12
申请号：JP2011171159
申请日：2011-08-04
申请人： Sadra Medical Inc , サドラ・メディカル・インコーポレーテッド
发明人： SALAHIEH AMR , BRANDT BRIAN D , MOREJOHN DWIGHT P , HAUG ULRICH R , DUERI JEAN-PIERRE , VALENCIA HANS F , GESHLIDER ROBERT A , KROLIK JEFF , SAUL TOM , ARGENTO CLAUDIO , HILDEBRAND DANIEL
IPC分类号： A61B17/00 , A61F2/01 , A61F2/24 , A61F2/90
CPC分类号： A61F2/013 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2230/0054 , A61F2250/006
摘要： PROBLEM TO BE SOLVED: To provide an apparatus for replacing a heart valve with a replacement valve in a blood vessel using an expandable and retrievable anchor.SOLUTION: The apparatus is an engagement member including: an expandable anchor 300 having a collapsed delivery configuration and a deployed configuration; the replacement valve attached to the expandable anchor 300; a first engagement member that is associated with a first anchor region and that forms a hole 306; and a second engagement member 308 that is associated with a second anchor region and that forms the hole 312 and includes a tab 310 extending into the hole 312. In the deployed configuration, the apparatus includes: the engagement member where the first engagement member engaged with the tab; and a replacement heart valve.
摘要翻译：要解决的问题：提供一种用于使用可扩张和可回收的锚来在血管中用替换瓣膜替换心脏瓣膜的装置。解决方案：该装置是一种接合构件，包括：可膨胀锚固件300，其具有折叠的输送构型和展开构型; 附接到可扩张锚300的替换阀; 第一接合构件，其与第一锚定区域相关联并且形成孔306; 以及第二接合构件308，其与第二锚固区域相关联并且形成孔312并且包括延伸到孔312中的突出部310.在展开构造中，该装置包括：接合构件，其中第一接合构件与标签和替换心脏瓣膜。版权所有（C）2012，JPO＆INPIT

9. 发明专利

ES2418106T3 Válvula cardíaca reposicionable 未知
公开(公告)号：ES2418106T3
公开(公告)日：2013-08-12
申请号：ES12179049
申请日：2004-12-22
申请人： SADRA MEDICAL INC , SADRA MEDICAL INC
发明人： SALAHIEH AMR , BRANDT BRIAN , MOREJOHN DWIGHT , HAUG ULRICH , DUERI JEAN-PIERRE , VALENCIA HANS , GESHLIDER ROBERT , KROLIK JEFF , SAUL TOM , ARGENTO CLAUDIO , HILDEBRAND DANIEL
IPC分类号： A61F2/24 , A61F2/01 , A61F2/90
摘要： Aparatos (10, 10', 10'', 450) para reemplazar una válvula aórtica original, comprendiendo el aparato (10, 10', 10'',450): un ancla (30, 30', 300, 350, 470) que comprende una brida expandible con extremos cerrados, estando adaptada elancla (30, 30', 300, 350, 470) colocada por vía endovascular y asegurada en un sitio de ancla dentro de la válvulaaórtica original, y una válvula de reemplazo (20, 354, 460) configurada para ser asegurada dentro del ancla (30, 30',300, 350, 470), en donde el ancla (30, 30', 300, 350, 470) comprende una interfase del sistema de despliegue proximal en un extremoproximal del ancla (30, 30', 300, 350, 470), estando adaptado a la interfase del sistema de despliegue proximal parapermitir que un sistema de despliegue aplique una fuerza dirigida distalmente sobre el extremo proximal del ancla (30,30', 300, 350, 470), y en donde la interfase del sistema de despliegue proximal está adaptada adicionalmente para expandirse radialmentedurante la aplicación de una fuerza dirigida distalmente sobre el extremo proximal del ancla (30, 30', 300, 350, 470).

10. 发明专利

CA2622430C TWO-PART PACKAGE FOR MEDICAL IMPLANT 未知
公开(公告)号：CA2622430C
公开(公告)日：2014-10-28
申请号：CA2622430
申请日：2006-09-11
申请人： SADRA MEDICAL INC
发明人： SALAHIEH AMR , SAUL TOM , GESHLIDER ROBERT , JOHNSON ANDREA , MOREJOHN DWIGHT , HILDEBRAND DANIEL , DUERI JEAN-PIERRE
IPC分类号： A61B19/02 , A61F2/24 , A61F2/95
摘要： The invention provides a two-part package and method of use for a pre-attached medical implant and delivery tool system. The package includes a wet compartment and a dry compartment and allows a pre-attached implant and delivery tool system to be at least partially stored immersed in a fluid in the wet compartment and at least partially stored in the dry compartment. In one embodiment the implant comprises a replacement heart valve, and the heart valve is stored inside the wet compartment while the heart valve delivery tool remains dry in the dry compartment.

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