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1. 发明申请

US20060099700A1 Halohydrin dehalogenases and related polynucleotides 有权
公开(公告)号：US20060099700A1
公开(公告)日：2006-05-11
申请号：US11266747
申请日：2005-11-02
申请人： S. Davis , Richard Fox , Gjalt Huisman , Vesna Gavrilovic , Emily Mundorff , Lisa Newman
发明人： S. Davis , Richard Fox , Gjalt Huisman , Vesna Gavrilovic , Emily Mundorff , Lisa Newman
IPC分类号： C07H21/04 , C12P21/06 , C12N9/88
CPC分类号： C12N9/14 , C12N9/88
摘要： The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.

2. 发明申请

US20050153417A1 Halohydrin dehalogenases and related polynucleotides 有权
标题翻译：卤代醇脱卤素酶和相关多核苷酸
公开(公告)号：US20050153417A1
公开(公告)日：2005-07-14
申请号：US10917179
申请日：2004-08-11
申请人： S. Davis , Richard Fox , Gjalt Huisman , Vesna Gavrilovic , Lisa Newman
发明人： S. Davis , Richard Fox , Gjalt Huisman , Vesna Gavrilovic , Lisa Newman
IPC分类号： C07H21/04 , C12N1/21 , C12N9/04 , C12N9/14 , C12N9/88 , C12N15/60 , C12N15/74 , C12Q1/68
CPC分类号： C12N9/88 , C12N9/14
摘要： The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
摘要翻译：本发明涉及新型卤代醇脱卤素酶多肽和编码它们的多核苷酸。这些多肽可用于制备4-取代-3-丁酸衍生物和连位氰基羟基取代的羧酸酯。本发明还提供相关载体，宿主细胞和方法。

3. 发明申请

US20050272064A1 Halohydrin dehalogenases and related polynucleotides 有权
公开(公告)号：US20050272064A1
公开(公告)日：2005-12-08
申请号：US11067323
申请日：2005-02-23
申请人： S. Davis , Richard Fox , Gjalt Huisman , Vesna Gavrilovic , Lisa Newman
发明人： S. Davis , Richard Fox , Gjalt Huisman , Vesna Gavrilovic , Lisa Newman
IPC分类号： C07H21/04 , C12N1/21 , C12N9/04 , C12N9/14 , C12N9/88 , C12N15/74 , C12Q1/68
CPC分类号： C12N9/14 , C12N9/88
摘要： The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.

4. 发明申请

US20060205003A1 Methods, systems, and software for identifying functional biomolecules 有权
标题翻译：用于鉴定功能性生物分子的方法，系统和软件
公开(公告)号：US20060205003A1
公开(公告)日：2006-09-14
申请号：US11429628
申请日：2006-05-05
申请人： Claes Gustafsson , Sridhar Govindarajan , Robin Emig , Richard Fox , Ajoy Roy , Jeremy Minshull , S. Davis , Anthony Cox , Phillip Patten , Linda Castle , Daniel Siehl , Rebecca Gorton , Teddy Chen
发明人： Claes Gustafsson , Sridhar Govindarajan , Robin Emig , Richard Fox , Ajoy Roy , Jeremy Minshull , S. Davis , Anthony Cox , Phillip Patten , Linda Castle , Daniel Siehl , Rebecca Gorton , Teddy Chen
IPC分类号： C40B40/08 , C40B50/02 , C40B30/02
CPC分类号： G06F19/18 , C40B30/02 , C40B50/02 , G06F19/22 , G06F19/24
摘要： The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.
摘要翻译：本发明一般涉及快速有效地搜索生物相关数据空间的方法。更具体地，本发明包括从复杂的生物分子文库或这些文库集合鉴定具有所需性质或最适合于获得这些性质的生物分子的方法。本发明还提供了对序列活性关系建模的方法。由于许多方法是计算机实现的，本发明另外提供用于执行这些方法的数字系统和软件。

5. 发明授权

US08264315B2 Linear variable differential transformers 有权
标题翻译：线性可变差动变压器
公开(公告)号：US08264315B2
公开(公告)日：2012-09-11
申请号：US12849659
申请日：2010-08-03
申请人： Richard Fox , Gene Holden , Robert Franconi
发明人： Richard Fox , Gene Holden , Robert Franconi
IPC分类号： H01F21/06
CPC分类号： H01F21/06 , G01D5/2291 , H01F2003/106
摘要： Linear variable differential transformers include a core comprising a non-ferromagnetic material and a ferromagnetic material, and a coil assembly including an axial bore within which the core is disposed and through which the core axially translates.
摘要翻译：线性可变差动变压器包括包含非铁磁材料和铁磁材料的芯，以及包括轴向孔的线圈组件，其中所述芯设置在该轴向孔中，并且芯轴线通过该轴线平移。

6. 发明申请

US20060205544A1 DYNAMIC TOY WITH INFLATABLE BLADDER 审中-公开
标题翻译：动感玩具与可充气刮刀
公开(公告)号：US20060205544A1
公开(公告)日：2006-09-14
申请号：US11276616
申请日：2006-03-08
申请人： Daniel Wyner , Richard Fox , Roger LaFlamme
发明人： Daniel Wyner , Richard Fox , Roger LaFlamme
IPC分类号： A63B43/00 , A63B67/14 , A63B41/12 , A63B43/04
CPC分类号： A63B43/04 , A63B41/00 , A63B41/12 , A63H27/10 , A63H33/18 , A63H2027/1033 , A63H2027/1075
摘要： An object with a dynamically changeable configuration is provided. The outer surface configuration and/or the weight displacement configuration can be dynamically changed to alter the characteristics of the object, which can be a toy, such as a football, baseball or flying disc. To change the outer configuration of the object, a cover having an outer surface and at least one aperture therethrough is provided. A surface changing member, such as a bladder, is urgable into the at least one aperture to dynamically change the outer surface of the object. To change the weight displacement of the object, the main body includes a first chamber and a second chamber therein where fluid, such as gas or liquid, can flow therebetween. The positioning of the fluid within the first chamber and the second chamber is controlled by a pump and valve system. As a result, the weight displacement of the object is dynamically changeable.
摘要翻译：提供了具有动态可变配置的对象。可以动态地改变外表面构型和/或重量位移构造以改变物体的特征，该物体可以是诸如足球，棒球或飞盘之类的玩具。为了改变物体的外部结构，提供了具有外表面和穿过其中的至少一个孔的盖。诸如膀胱的表面改变构件可以紧紧地插入到至少一个孔中以动态地改变物体的外表面。为了改变物体的重量位移，主体包括第一室和第二室，其中诸如气体或液体的流体可以在其间流动。流体在第一室和第二室内的定位由泵和阀系统控制。因此，物体的重量位移是动态变化的。

7. 发明申请

US20050183575A1 Adapter for low volume air sampler 失效
标题翻译：适用于低容量空气取样器
公开(公告)号：US20050183575A1
公开(公告)日：2005-08-25
申请号：US10788090
申请日：2004-02-25
申请人： Richard Fox
发明人： Richard Fox
IPC分类号： G01N1/24 , B01D46/00
CPC分类号： G01N1/24
摘要： An adapter for use with a low volume PUF sampler is described. The adapter is affixed over the open end of a PUF (polyurethane foam) sample cartridge. Sample tubing is affixed to an aperture in the adapter, and the free end of the sample tubing is then positioned at a desired sample location such as within an aircraft interior. As a vacuum is applied to the PUF cartridge, the adapter allows air collected at the sample point to pass through the tubing and through the interior of the PUF cartridge while preventing air surrounding the PUF cartridge from being drawn into the PUF cartridge except through the sample tubing. In this manner the sample point of a desired air sample can be selected at a point remote from the PUF cartridge. Additionally, use of multiple PUF cartridges and adapters allows the simultaneous collection of separate air samples.
摘要翻译：描述了一种用于低体积PUF取样器的适配器。适配器固定在PUF（聚氨酯泡沫）样品盒的开口端上。样品管固定在适配器的孔中，然后将样品管的自由端定位在所需的样品位置，例如飞机内部。当真空被施加到PUF筒时，适配器允许在样品点处收集的空气通过管道并穿过PUF筒的内部，同时防止PUF筒周围的空气被吸入PUF筒中，除了通过样品管道。以这种方式，可以在远离PUF盒的点处选择所需空气样品的采样点。此外，使用多个PUF墨盒和适配器可以同时收集单独的空气样品。

8. 发明授权

US5192265A Adjustable-resistance anti-siphon device 失效
标题翻译：可调电阻防虹吸装置
公开(公告)号：US5192265A
公开(公告)日：1993-03-09
申请号：US625268
申请日：1990-12-10
申请人： James M. Drake , Richard Fox , Andre Bahoric
发明人： James M. Drake , Richard Fox , Andre Bahoric
IPC分类号： A61M27/00
CPC分类号： A61M27/006
摘要： An adjustable-resistance anti-siphon device for a cerebrospinal fluid shunt is provided. The device has a substantially rigid housing having an internal cavity which contains a first chamber and a second chamber, the first chamber having at least one flexible wall, an inlet port and an outlet port, the ports passing through apertures in the housing; the second chamber being gas-filled and being in pressure communication with at least a portion of the at least one flexible wall of the first chamber; and gas pressure control means connected to said gas-filled chamber whereby the pressure in said gas-filled chamber may be adjusted.
摘要翻译：提供了一种用于脑脊液分流的可调电阻抗虹吸装置。该装置具有基本刚性的壳体，其具有包含第一腔室和第二腔室的内腔，第一腔室具有至少一个柔性壁，入口端口和出口端口，所述孔口穿过壳体中的孔; 所述第二室被充气并且与所述第一室的所述至少一个柔性壁的至少一部分压力连通; 以及连接到所述充气室的气体压力控制装置，由此可以调节所述充气室中的压力。

9. 发明授权

US09120151B2 Methods for manufacturing titanium aluminide components from articles formed by consolidation processes 有权
标题翻译：从固结过程形成的制品中制备铝化铝组分的方法
公开(公告)号：US09120151B2
公开(公告)日：2015-09-01
申请号：US13564656
申请日：2012-08-01
申请人： Donald G. Godfrey , Mark C. Morris , George Reimer , William F. Hehmann , Daira Legzdina , Richard Fox , Yiping Hu , Harry Lester Kington
发明人： Donald G. Godfrey , Mark C. Morris , George Reimer , William F. Hehmann , Daira Legzdina , Richard Fox , Yiping Hu , Harry Lester Kington
IPC分类号： C23C16/06 , C23C16/48 , B05D3/12 , B05D7/14 , B22F3/12 , B22F3/15 , C23C10/48 , C23C10/60 , C22C1/04 , C23C14/16 , B22F3/105
CPC分类号： B22F3/1266 , B22F3/1055 , B22F3/15 , B33Y70/00 , B33Y80/00 , C22C1/0491 , C23C10/48 , C23C10/60 , C23C14/16 , Y02P10/295 , Y10T428/12764
摘要： Substantially defect-free titanium aluminide components and methods are provided for manufacturing the same from articles formed by consolidation processes. The method includes providing an intermediate article comprised of a titanium aluminide alloy and formed by a consolidation process. The intermediate article is encapsulated with an aluminum-containing encapsulation layer. The intermediate article is compacted after the encapsulation step. A substantially defect-free titanium aluminide component comprises a compacted three-dimensional article comprised of titanium aluminide and formed by a consolidation process and an aluminum-containing encapsulation layer on at least one surface of the compacted three-dimensional article. The aluminum-containing encapsulation layer comprises an aluminide material, MCrAlY wherein M is cobalt, nickel, or a combination of cobalt and nickel, or TiAlCr.
摘要翻译：提供了基本上无缺陷的钛铝化合物组分和方法，用于通过固化方法形成的制品来制造它们。该方法包括提供由钛化铝合金构成的中间制品，并通过固结方法形成。中间制品用含铝封装层包封。中间制品在封装步骤之后被压实。基本上无缺陷的钛铝化物组分包括由铝化钛组成的压实的三维制品，并且通过固结方法形成，并且在压实的三维制品的至少一个表面上包含含铝封装层。含铝封装层包括铝化物材料MCrAlY，其中M是钴，镍或钴和镍的组合，或TiAlCr。

10. 发明申请

US20130285777A1 HIGH TEMPERATURE ELECTROMAGNETIC COIL ASSEMBLIES INCLUDING BRAIDED LEAD WIRES AND METHODS FOR THE FABRICATION THEREOF 有权
标题翻译：高温电磁线圈组件，其中包括布线引线及其制造方法
公开(公告)号：US20130285777A1
公开(公告)日：2013-10-31
申请号：US13460460
申请日：2012-04-30
申请人： James Piascik , Jacob Harding , Eric Passman , Robert Franconi , Richard Fox
发明人： James Piascik , Jacob Harding , Eric Passman , Robert Franconi , Richard Fox
IPC分类号： H01F5/00 , H01F41/10
CPC分类号： H01F5/04 , H01F27/327 , H01F41/10 , H01F41/127 , Y10T29/49071
摘要： Embodiments of an electromagnetic coil assembly are provided, as are methods for the manufacture of an electromagnetic coil assembly. In one embodiment, the electromagnetic coil assembly includes coiled magnet wire and a braided lead wire, which has a first end segment electrically coupled to the coiled magnet wire and having a second end segment. The electromagnetic coil assembly further includes an electrically-conductive member to which the second end segment of the braided lead wire is crimped.
摘要翻译：提供电磁线圈组件的实施例，以及用于制造电磁线圈组件的方法。在一个实施例中，电磁线圈组件包括线圈电磁线和编织引线，其具有电耦合到线圈电磁线并具有第二端段的第一端段。电磁线圈组件还包括导电构件，编织引线的第二端段被压接到该导电构件。

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