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    • 5. 发明授权
    • Process for production of 5-arylpentanols
    • 5-芳基戊醇的制备方法
    • US06600079B2
    • 2003-07-29
    • US10254661
    • 2002-09-26
    • Akira UmadaShigeyoshi Tanaka
    • Akira UmadaShigeyoshi Tanaka
    • C07C2700
    • C07C29/17C07C33/20
    • A process for producing a 5-arylpentanol of formula (2): wherein R1 represents an aryl group which may be substituted with one or two or more of an alkyl or alkoxy group and has 6 to 12 carbon atoms in total, R3 represents a hydrogen atom, or an alkyl or alkenyl group of 1 to 6 carbon atoms, and R4 represents R2 defined below when R2 is a monovalent group or represents R2H when R2 is a divalent group, which comprises effecting hydrogenolysis of a pyran compound of formula (1): wherein, R1 and R3 are as defined above, R2 represents a hydrogen atom, an alkyl or alkenyl group of 1 to 6 carbon atoms, or an alkylidene or alkenylidene group of 1 to 6 carbon atoms, and a dotted line represents a possible bond and any one of the three bonds represented by dotted lines and solid lines is a double bond, in the presence of one or more catalysts selected from (a) a catalyst carrying two or more elements selected from noble metals in Group VIII in the periodic table and (b) an acid type palladium-supporting catalyst. 5-arylpentanols can be prepared in a high yield with low production of hydrocarbons without causing a problem with regard to corrosion of process equipment.
    • 一种制备式(2)的5-芳基戊醇的方法:其中R 1表示可被一个或两个或多个烷基或烷氧基取代并且总共具有6至12个碳原子的芳基,R 3表示氢 原子或1〜6个碳原子的烷基或烯基,R4表示当R2为一价基团时定义的R2,或R2表示二价基团时为R2H,其包括使式(1)的吡喃化合物进行氢解, 其中,R 1和R 3如上定义,R 2表示氢原子,1〜6个碳原子的烷基或链烯基或碳原子数为1〜6的亚烷基或亚链烯基,虚线表示可能的键 并且在一种或多种催化剂的存在下,由虚线和实线表示的三个键中的任一个是双键,所述催化剂选自(a)载有选自元素周期表中第Ⅷ族中的贵金属的两种或更多种元素的催化剂 和(b)酸型钯 - 移植催化剂。 5-芳基戊醇可以以高产率制备,低产烃量,而不会对工艺设备的腐蚀造成问题。