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1. 发明授权

US5079959A Analyzing system using sheath flow of sample 失效
标题翻译：使用样品的流动分析系统
公开(公告)号：US5079959A
公开(公告)日：1992-01-14
申请号：US404559
申请日：1989-09-08
申请人： Ryo Miyake , Hiroshi Ohki , Isao Yamazaki , Toshio Kaneko , Hideyuki Horiuchi , Shinichi Sakuraba , Kaori Yasuda
发明人： Ryo Miyake , Hiroshi Ohki , Isao Yamazaki , Toshio Kaneko , Hideyuki Horiuchi , Shinichi Sakuraba , Kaori Yasuda
IPC分类号： G01N15/12 , G01N15/14 , G01N35/10
CPC分类号： G01N35/1083 , G01N15/1404 , G01N2035/1086 , G01N35/1004
摘要： Particles contained in a liquid sample are analyzed by moving the particles along a detection passage past a detector using a liquid flow in the detection passage. To reduce the time required for analysis of each sample, the sample is delivered at an input location at the upstream end of the detection passage by movement of a movable container carrying the sample to the input location. Immediately after the commencement of the delivery of the liquid sample, liquid flow is caused to occur in the detection passage. Washing liquid is supplied to the input location by a liquid supplier different from the movable container which carries the sample.

2. 发明申请

US20130059341A1 METHOD FOR PRODUCING GLUCURONIC ACID CONJUGATE USING SACCHAROMYCES CEREVISIAE 有权
标题翻译：使用细菌培养基生产葡萄糖酸的方法
公开(公告)号：US20130059341A1
公开(公告)日：2013-03-07
申请号：US13580316
申请日：2011-02-14
申请人： Shinichi Ikushiro , Toshiyuki Sakaki , Kaori Yasuda
发明人： Shinichi Ikushiro , Toshiyuki Sakaki , Kaori Yasuda
IPC分类号： C12P19/60 , C12N15/81 , C12P19/44 , C12N1/19
CPC分类号： C12N15/81 , C12N9/0006 , C12N9/1051 , C12P19/44
摘要： Provided is a new method for producing a glucuronide, having excellent productivity and being replaceable with a method using Saccharomyces pombe, and to provide a new means used in this production method. Disclosed are: a transformed Saccharomyces cerevisiae wherein a gene coding for a UDP-glucose dehydrogenase and a gene coding for a UDP-glucose transferase are inserted in a manner such that said genes can be expressed; a transformed Saccharomyces cerevisiae wherein a gene coding for a cytochrome P450 gene is further inserted in a manner such that said gene can be expressed; and a method for producing a glucaronide that includes culturing transformed Saccharomyces cerevisiae in the presence of glucose and a substance to be conjugated, generating the glucuronide of the aforementioned substance to be conjugated.
摘要翻译：提供一种生产葡萄糖醛酸苷的新方法，具有优异的生产率并且可以用使用酿酒酵母的方法替代，并提供在该生产方法中使用的新方法。公开了：转化的酿酒酵母，其中以可以表达所述基因的方式插入编码UDP-葡萄糖脱氢酶的基因和编码UDP-葡萄糖转移酶的基因; 转化的酿酒酵母，其中编码细胞色素P450基因的基因进一步以能够表达所述基因的方式插入; 以及一种生产葡糖多糖的方法，其包括在葡萄糖和待共轭物质的存在下培养转化的酿酒酵母，产生待共轭的上述物质的葡糖苷酸。

3. 发明授权

US08741602B2 Method for producing glucuronic acid conjugate using Saccharomyces cerevisiae 有权
标题翻译：使用酿酒酵母生产葡萄糖醛酸结合物的方法
公开(公告)号：US08741602B2
公开(公告)日：2014-06-03
申请号：US13580316
申请日：2011-02-14
申请人： Shinichi Ikushiro , Toshiyuki Sakaki , Kaori Yasuda
发明人： Shinichi Ikushiro , Toshiyuki Sakaki , Kaori Yasuda
IPC分类号： C12N15/81
CPC分类号： C12N15/81 , C12N9/0006 , C12N9/1051 , C12P19/44
摘要： Provided is a new method for producing a glucuronide, having excellent productivity and being replaceable with a method using Saccharomyces pombe, and to provide a new means used in this production method. Disclosed are: a transformed Saccharomyces cerevisiae wherein a gene coding for a UDP-glucose dehydrogenase and a gene coding for a UDP-glucose transferase are inserted in a manner such that said genes can be expressed; a transformed Saccharomyces cerevisiae wherein a gene coding for a cytochrome P450 gene is further inserted in a manner such that said gene can be expressed; and a method for producing a glucaronide that includes culturing transformed Saccharomyces cerevisiae in the presence of glucose and a substance to be conjugated, generating the glucuronide of the aforementioned substance to be conjugated.
摘要翻译：提供一种生产葡萄糖醛酸苷的新方法，具有优异的生产率并且可以用使用酿酒酵母的方法替代，并提供在该生产方法中使用的新方法。公开了：转化的酿酒酵母，其中以可以表达所述基因的方式插入编码UDP-葡萄糖脱氢酶的基因和编码UDP-葡萄糖转移酶的基因; 转化的酿酒酵母，其中编码细胞色素P450基因的基因进一步以能够表达所述基因的方式插入; 以及一种生产葡糖多糖的方法，其包括在葡萄糖和待共轭物质的存在下培养转化的酿酒酵母，产生待共轭的上述物质的葡糖苷酸。

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