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1. 发明申请

US20110054172A1 PYRIDYLAMINOACETIC ACID COMPOUND 有权
标题翻译：吡啶酰胺酸化合物
公开(公告)号：US20110054172A1
公开(公告)日：2011-03-03
申请号：US12922028
申请日：2009-03-12
申请人： Ryo Iwamura , Masayuki Tanaka , Tetsushi Katsube , Manabu Shigetomi , Eiji Okanari , Yasunori Tokunaga , Hiroshi Fujiwara
发明人： Ryo Iwamura , Masayuki Tanaka , Tetsushi Katsube , Manabu Shigetomi , Eiji Okanari , Yasunori Tokunaga , Hiroshi Fujiwara
IPC分类号： C07D401/14 , C07D417/14 , C07D401/12 , C07D405/14 , C07D417/12
CPC分类号： C07D417/14 , A61K9/0053 , A61K9/2018 , A61K9/4858 , C07D213/74 , C07D401/14 , C07D405/14 , C07D409/14 , C07D417/12
摘要： The present invention provides a novel pyridylaminoacetic acid compound represented by the following formula (1): (wherein R1, R2, R3, Y and Z are as defined in the description and claims), or a pharmacologically acceptable salt thereof. The pyridylaminoacetic acid compound has EP2 agonistic action and is therefore useful as a therapeutic and/or prophylactic agent for respiratory diseases such as asthma or chronic obstructive pulmonary disease.
摘要翻译：本发明提供由下式（1）表示的新颖的吡啶基氨基乙酸化合物或其药学上可接受的盐，其中R1，R2，R3，Y和Z如说明书和权利要求中所定义。吡啶基氨基乙酸化合物具有EP2激动作用，因此可用作呼吸系统疾病如哮喘或慢性阻塞性肺疾病的治疗和/或预防剂。

2. 发明申请

US20120259123A1 AMINOPYRIDINE COMPOUND 审中-公开
标题翻译：氨基吡啶化合物
公开(公告)号：US20120259123A1
公开(公告)日：2012-10-11
申请号：US13518824
申请日：2010-12-24
申请人： Ryo Iwamura , Masayuki Tanaka , Tetsushi Katsube , Nobuhiko Shibakawa , Manabu Shigetomi , Eiji Okanari , Tomoko Kanda , Yasunori Tokunaga , Hiroshi Fujiwara
发明人： Ryo Iwamura , Masayuki Tanaka , Tetsushi Katsube , Nobuhiko Shibakawa , Manabu Shigetomi , Eiji Okanari , Tomoko Kanda , Yasunori Tokunaga , Hiroshi Fujiwara
IPC分类号： C07D213/72 , C07D409/12 , C07D401/02 , C07D409/14
CPC分类号： C07D213/74 , C07D401/12 , C07D405/12 , C07D409/12 , C07D409/14 , C07D417/12
摘要： The present invention relates to a compound represented by the formula (I): or a pharmaceutically acceptable salt thereof, a medical composition containing the same, and a medical composition for the treatment or prophylaxis of respiratory diseases or glaucoma.
摘要翻译：本发明涉及由式（I）表示的化合物或其药学上可接受的盐，含有该化合物的医药组合物和用于治疗或预防呼吸系统疾病或青光眼的医药组合物。

3. 发明授权

US08648097B2 Pyridylaminoacetic acid compound 有权
标题翻译：吡啶基氨基乙酸化合物
公开(公告)号：US08648097B2
公开(公告)日：2014-02-11
申请号：US12922028
申请日：2009-03-12
申请人： Ryo Iwamura , Masayuki Tanaka , Tetsushi Katsube , Manabu Shigetomi , Eiji Okanari , Yasunori Tokunaga , Hiroshi Fujiwara
发明人： Ryo Iwamura , Masayuki Tanaka , Tetsushi Katsube , Manabu Shigetomi , Eiji Okanari , Yasunori Tokunaga , Hiroshi Fujiwara
IPC分类号： A61K31/4439 , C07D401/14
CPC分类号： C07D417/14 , A61K9/0053 , A61K9/2018 , A61K9/4858 , C07D213/74 , C07D401/14 , C07D405/14 , C07D409/14 , C07D417/12
摘要： The present invention provides a novel pyridylaminoacetic acid compound represented by the following formula (1): (wherein R1, R2, R3, Y and Z are as defined in the description and claims), or a pharmacologically acceptable salt thereof. The pyridylaminoacetic acid compound has EP2 agonistic action and is therefore useful as a therapeutic and/or prophylactic agent for respiratory diseases such as asthma or chronic obstructive pulmonary disease.
摘要翻译：本发明提供由下式（1）表示的新颖的吡啶基氨基乙酸化合物或其药学上可接受的盐，其中R1，R2，R3，Y和Z如说明书和权利要求中所定义。吡啶基氨基乙酸化合物具有EP2激动作用，因此可用作呼吸系统疾病如哮喘或慢性阻塞性肺疾病的治疗和/或预防剂。

4. 发明授权

US07309718B2 Dibenzocycloheptene compound 失效
标题翻译：二苯并环庚烯化合物
公开(公告)号：US07309718B2
公开(公告)日：2007-12-18
申请号：US10481752
申请日：2002-06-27
申请人： Yoshiaki Kuroki , Hitoshi Ueno , Tetsushi Katsube , Tetsuo Kawaguchi , Eiji Okanari , Ichiro Tanaka , Masayuki Tanaka , Masahiko Hagihara
发明人： Yoshiaki Kuroki , Hitoshi Ueno , Tetsushi Katsube , Tetsuo Kawaguchi , Eiji Okanari , Ichiro Tanaka , Masayuki Tanaka , Masahiko Hagihara
IPC分类号： A61K31/19 , C07C61/00 , C07C63/00
CPC分类号： C07D215/18 , C07D215/12
摘要： The present invention discloses a dibenzocycloheptene compound represented by the formula (I): wherein R1: hydrogen atom, halogen atom, etc., R2: hydrogen atom, halogen atom, etc., A: 5-membered or 6-membered heteroaromatic ring group containing 1 to 3 hetero atom(s) selected from the group consisting of nitrogen atom, oxygen atom and sulfur atom, and the heteroaromatic ring group, etc. may have halogen atom, nitrogen atom, etc. as substituent(s), B: formula; —CH═CH—, formula; —CH2O—, etc., Y: C1-C10 alkylene group which may have halogen atom, etc. as substituent(s), etc., Z: carboxyl group which may be protected, etc., m: an integer of 1 to 4, n: an integer of 1 to 3, represents a single bond or a double bond, or a pharmaceutically acceptable salt thereof and a medical composition containing the same as an effective ingredient which has leukotriene C4 antagonistic action and leukotriene E4 antagonistic action in addition to potent leukotriene D4 antagonistic action, and useful as antiasthmatic agent, antiallergic agent and anti-inflammatory agent.
摘要翻译：本发明公开了式（I）表示的二苯并环庚烯化合物：其中R 1：氢原子，卤素原子等，R 2：氢原子，卤素原子等，含有1〜3个选自氮原子，氧原子和硫原子的杂原子的5元或6元杂芳族环基和杂芳环基等可以具有卤素原子，氮原子等作为取代基，B：式; -CH-CH-，式 -CH 2 O - 等，Y：C 1 -C 10亚烷基，其可以具有卤素原子等作为取代基（ s）等，Z：可被保护的羧基等，m：1〜4的整数，n：1〜3的整数，表示单键或双键，或其药学上可接受的盐和含有与有效成分相同的药物组合物，除了有效的白三烯外，还具有白三烯C 4拮抗作用和白三烯E 4拮抗作用 D 4拮抗作用，可用作止喘剂，抗过敏剂和抗炎剂。

5. 发明申请

US20090036453A1 Pyrrolopyridazinone Compound 失效
公开(公告)号：US20090036453A1
公开(公告)日：2009-02-05
申请号：US12087864
申请日：2007-01-16
申请人： Masahiko Hagihara , Masayuki Tanaka , Tetsushi Katsube , Makoto Okudo , Noriaki Iwase , Manabu Shigetomi , Tomoko Kanda , Takayuki Nakanishi
发明人： Masahiko Hagihara , Masayuki Tanaka , Tetsushi Katsube , Makoto Okudo , Noriaki Iwase , Manabu Shigetomi , Tomoko Kanda , Takayuki Nakanishi
IPC分类号： A61K31/5025 , C07D487/02 , A61P11/00 , A61P9/00 , A61P37/00
CPC分类号： C07D487/04
摘要： The present invention discloses a pyrrolopyridazinone compound represented by the formula (1): wherein R1 represents C1-C2 alkyl group or halogeno C1-C2 alkyl group, R2 repersents C3-C5 cycloalkyl group, (C3-C5 cycloalkyl)C1-C2 alkyl group or C1-C3 alkyl group, R3 represents hydrogen atom, or methylene group or cis-vinylene group for forming substituted oxygen-containing hetero ring in combination with group —O—R2, R4 represents hydrogen atom, halogen atom, C1-C8 alkyl group, C2-C6 alkenyl group, C2-C6 alkynyl group, hydroxy C3-C6 alkenyl group, hydroxy C3-C6 alkynyl group, C1-C6 alkyl group substituted by substituent(s) selected from Substituent group (a), C3-C6 cycloalkyl group which may be substituted by substituent(s) selected from Substituent group (b), “C1-C3 alkyl group which is substituted by C3-C6 cycloalkyl group which may be substituted by substituent(s) selected from Substituent group (b), and which may be substituted by a hydroxy group”, an aromatic ring group or heteroaromatic ring group each of which may be substituted by a substituent(s) selected from Substituent group (c) or “C1-C2 alkyl group which is substituted by aromatic ring group or heteroaromatic ring group each of which may be substituted by group(s) selected from Substituent group (c), and which may be substituted by a hydroxy group”, Substituent group (a) represents a halogen atom, hydroxy group, cyano group, carboxy group, C1-C5 alkoxy group, halogeno C1-C4 alkoxy group, C3-C6 cycloalkoxy group, (C3-C6 cycloalkyl)C1-C2 alkoxy group, C1-C4 alkoxycarbonyl group, C2-C4 alkanoyl group, C2-C4 alkanoyloxy group or C1-C4 alkyl-substituted amino group, Substituent group (b) represents a hydroxy group or a halogen atom, Substituent group (c) represents a halogen atom, a hydroxy group, a cyano group, a nitro group, a carboxy group, C1-C5 alkoxy group, C1-C4 alkoxycarbonyl group, C2-C4 alkanoyloxy group, C1-C4 alkyl-substituted amino group or a C1-C4 alkyl group which may be substituted by a substituent(s) selected from the group consisting of (a halogen atom, a hydroxy group and a carboxy group), or a pharmaceutically acceptable salt thereof.

6. 发明授权

US08450319B2 Pyrrolopyridazinone compound 失效
标题翻译：吡咯并哒嗪酮化合物
公开(公告)号：US08450319B2
公开(公告)日：2013-05-28
申请号：US12087864
申请日：2007-01-16
申请人： Masahiko Hagihara , Masayuki Tanaka , Tetsushi Katsube , Makoto Okudo , Noriaki Iwase , Manabu Shigetomi , Tomoko Kanda , Takayuki Nakanishi
发明人： Masahiko Hagihara , Masayuki Tanaka , Tetsushi Katsube , Makoto Okudo , Noriaki Iwase , Manabu Shigetomi , Tomoko Kanda , Takayuki Nakanishi
IPC分类号： C07D487/04 , A61K31/5025 , A61P29/00
CPC分类号： C07D487/04
摘要： The present invention discloses a pyrrolopyridazinone compound represented by the formula (1): useful, for example, as an anti-inflammatory agent or an inhibitor of respiratory tract contraction.
摘要翻译：本发明公开了由式（1）表示的吡咯并哒嗪酮化合物：例如可用作抗炎剂或呼吸道收缩抑制剂。

7. 发明授权

US08791521B2 Semiconductor device and method of manufacturing the same 有权
标题翻译：半导体装置及其制造方法
公开(公告)号：US08791521B2
公开(公告)日：2014-07-29
申请号：US13423664
申请日：2012-03-19
申请人： Koji Nakahara , Kazuhiro Matsuo , Masayuki Tanaka , Hirofumi Iikawa
发明人： Koji Nakahara , Kazuhiro Matsuo , Masayuki Tanaka , Hirofumi Iikawa
IPC分类号： H01L29/788
CPC分类号： H01L27/11521 , H01L29/42324 , H01L29/7881
摘要： A semiconductor device includes an interelectrode insulating film formed between a charge storage layer and a control electrode layer. The interelectrode insulating film is formed in a first region above an upper surface of an element isolation insulating film, a second region along a sidewall of the charge storage layer, and a third region above an upper surface of the charge storage layer. The interelectrode insulating film includes a first stack including a first silicon nitride film or a high dielectric constant film interposed between a first and a second silicon oxide film or a second stack including a second high dielectric constant film and a third silicon oxide film, and a second silicon nitride film formed between the control electrode layer and the first or the second stack. The second silicon nitride film is relatively thinner in the third region than in the first region.
摘要翻译：半导体器件包括在电荷存储层和控制电极层之间形成的电极间绝缘膜。电极间绝缘膜形成在元件隔离绝缘膜的上表面上方的第一区域，沿着电荷存储层的侧壁的第二区域和电荷存储层的上表面上方的第三区域。电极间绝缘膜包括：第一堆叠，其包括介于第一和第二氧化硅膜之间的第一氮化硅膜或高介电常数膜，或包括第二高介电常数膜和第三氧化硅膜的第二堆叠，形成在控制电极层和第一或第二堆叠之间的第二氮化硅膜。在第三区域中，第二氮化硅膜比第一区域相对薄。

8. 发明授权

US08525252B2 Nonvolatile semiconductor memory device and method of fabricating the same 有权
公开(公告)号：US08525252B2
公开(公告)日：2013-09-03
申请号：US13233788
申请日：2011-09-15
申请人： Kenichiro Toratani , Masayuki Tanaka , Kazuhiro Matsuo
发明人： Kenichiro Toratani , Masayuki Tanaka , Kazuhiro Matsuo
IPC分类号： H01L29/792
CPC分类号： H01L29/792 , G11C16/0466 , H01L21/28282 , H01L27/11568 , H01L27/11582 , H01L29/4234 , H01L29/66833 , H01L29/7926
摘要： According to one embodiment, a nonvolatile semiconductor memory device includes a semiconductor region, a tunnel insulator provided above the semiconductor region, a charge storage insulator provided above the tunnel insulator, a block insulator provided above the charge storage insulator, a control gate electrode provided above the block insulator, and an interface region including a metal element, the interface region being provided at one interface selected from between the semiconductor region and the tunnel insulator, the tunnel insulator and the charge storage insulator, the charge storage insulator and the block insulator, and the block insulator and the control gate electrode.

9. 发明申请

US20130119531A1 SEMICONDUCTOR DEVICE AND METHOD FOR MANUFACTURING THE SAME 有权
标题翻译：半导体器件及其制造方法
公开(公告)号：US20130119531A1
公开(公告)日：2013-05-16
申请号：US13423818
申请日：2012-03-19
申请人： Masayuki Tanaka , Kenichiro Toratani
发明人： Masayuki Tanaka , Kenichiro Toratani
IPC分类号： H01L23/48 , H01L21/283
CPC分类号： H01L27/11578 , H01L21/02164 , H01L21/02271 , H01L21/02304 , H01L21/28273 , H01L21/28282 , H01L27/11521 , H01L27/11568 , H01L27/11582 , H01L29/94
摘要： According to one embodiment, a method for manufacturing a semiconductor device includes: forming an underlayer film that contains atoms selected from the group consisting of aluminum, boron and alkaline earth metal; and forming a silicon oxide film on the underlayer film by a CVD method or an ALD method by use of a silicon source containing at least one of an ethoxy group, a halogen group, an alkyl group and an amino group, or a silicon source of a siloxane system.
摘要翻译：根据一个实施例，制造半导体器件的方法包括：形成含有选自铝，硼和碱土金属的原子的底层膜; 或通过使用含有乙氧基，卤素基团，烷基和氨基中的至少一个的硅源或硅源的硅源，通过CVD法或ALD法在下层膜上形成氧化硅膜硅氧烷体系。

10. 发明申请

US20130084027A1 IMAGE PROCESSING APPARATUS 有权
标题翻译：图像处理设备
公开(公告)号：US20130084027A1
公开(公告)日：2013-04-04
申请号：US13578542
申请日：2011-02-10
申请人： Shunichi Koga , Masayuki Tanaka , Masatoshi Okutomi
发明人： Shunichi Koga , Masayuki Tanaka , Masatoshi Okutomi
IPC分类号： G06K9/32
CPC分类号： G06K9/32 , G06T3/4053 , H04N1/3871 , H04N5/232
摘要： [Problem]An object of the present invention is to provide an image processing apparatus used for acquisition assistance of optimal low-resolution image set for super-resolution processing.[Means for solving the problem]The image processing apparatus of the present invention comprises a processing unit for computing displacement amounts between a basis image and each reference image, a processing unit for generating a plurality of deformed images based on the displacement amounts, the basis image and a plurality of reference images, a processing unit for setting a threshold of a parameter used at the time of image information selection, a processing unit for selecting image information used in the super-resolution processing from the reference image by using the threshold of the parameter, a processing unit for generating composed images and weighted images based on the basis image, the displacement amounts and the image information, a processing unit for generating high-resolution grid images by dividing the composed image by the weighted image, a processing unit for generating simplified interpolation images based on high-resolution grid images, a processing unit for generating assistance images, a display unit for displaying the assistance images, and a control unit that respectively controls a processing concerning the image input, a processing concerning the basis image selection, a processing concerning the reference image selection and a processing concerning the threshold setting of the parameter as necessary.
摘要翻译：本发明的目的是提供一种用于超分辨率处理的最佳低分辨率图像集的获取辅助的图像处理装置。解决问题的手段本发明的图像处理装置包括：处理单元，用于计算基础图像和每个参考图像之间的位移量;处理单元，用于基于位移量产生多个变形图像;基础图像和多个参考图像，用于设置在图像信息选择时使用的参数的阈值的处理单元，用于从参考图像中选择用于超分辨率处理的图像信息的处理单元，所述参数，用于基于所述基础图像生成合成图像和加权图像的处理单元，所述位移量和所述图像信息，用于通过将所述合成图像除以所述加权图像来生成高分辨率网格图像的处理单元，处理单元用于生成基于高分辨率网格图像的简化插值图像的处理单元生成辅助图像，用于显示辅助图像的显示单元和分别控制与图像输入有关的处理的控制单元，关于基础图像选择的处理，关于参考图像选择的处理以及关于阈值设置的处理必要的参数。

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