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1. 发明申请

US20110009940A1 VASCULAR AND BODILY DUCT TREATMENT DEVICES AND METHODS 有权
标题翻译：血管和体液治疗装置及方法
公开(公告)号：US20110009940A1
公开(公告)日：2011-01-13
申请号：US12573676
申请日：2009-10-05
申请人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Emily Vu , Kirk L. Pedersen , Craig L. Bonsignore , Elliot H. Sanders
发明人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Emily Vu , Kirk L. Pedersen , Craig L. Bonsignore , Elliot H. Sanders
IPC分类号： A61F2/06
CPC分类号： A61F2/90 , A61F2/91 , A61F2230/0008
摘要： A device including a self-expandable member having a proximal end portion, a main body portion and a distal end portion. Each of the self-expandable portions consists of a plurality of cell structures formed by intersecting strut members. In one implementation, at least one proximal cell structure in the proximal end portion has one or more struts that have a width and/or thickness greater than the width and/or thickness of the majority of strut members in the main body and distal end portions of the expandable member. Attached to at least one of the proximal-most cell structures in the proximal end portion is a proximally extending flexible wire having sufficient length and flexibility to navigate the tortuous vasculature of a patient. In another implementation, the device is delivered to the treatment site through the lumen of a delivery catheter.
摘要翻译：一种装置，包括具有近端部分，主体部分和远端部分的自扩张部件。每个自展开部分由通过相交的支柱构件形成的多个单元结构组成。在一个实施方案中，近端部分中的至少一个近端细胞结构具有一个或多个支柱，其具有大于主体中的大多数支柱构件的宽度和/或厚度的宽度和/或厚度，并且远端部分的可扩张构件。近端部分中的至少一个最近端的细胞结构附着有近端延伸的柔性丝，其具有足够的长度和柔性以导航患者的弯曲脉管系统。在另一实施方案中，该装置通过输送导管的内腔被输送到治疗部位。

2. 发明授权

US08795317B2 Embolic obstruction retrieval devices and methods 有权
标题翻译：栓塞梗阻检索装置及方法
公开(公告)号：US08795317B2
公开(公告)日：2014-08-05
申请号：US12499713
申请日：2009-07-08
申请人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Emily Vu , Kirk L. Pedersen , Craig L. Bonsignore , Elliot H. Sanders
发明人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Emily Vu , Kirk L. Pedersen , Craig L. Bonsignore , Elliot H. Sanders
IPC分类号： A61F2/01 , A61B17/22
CPC分类号： A61B17/221 , A61B2017/00867 , A61B2017/2215 , A61B2017/2217
摘要： An embolic obstruction retrieval device including a self-expandable member having a proximal end portion, a main body portion and a distal end portion. Each of the self-expandable portions consists of a plurality of cell structures formed by intersecting strut members. At least one proximal cell structure in the proximal end portion has one or more struts that have a width and/or thickness greater than the width and/or thickness of the majority of strut members in the main body and distal end portions of the expandable member. Attached to at least one of the proximal-most cell structures in the proximal end portion is a proximally extending flexible wire having sufficient length and flexibility to navigate the tortuous vasculature and access the embolic obstruction. In one implementation, the embolic obstruction retrieval device is delivered to the embolic obstruction through the lumen of a delivery catheter.
摘要翻译：一种栓塞性梗塞取出装置，其包括具有近端部分，主体部分和远端部分的自扩张部件。每个自展开部分由通过相交的支柱构件形成的多个单元结构组成。近端部分中的至少一个近端细胞结构具有一个或多个支柱，该支柱的宽度和/或厚度大于主体中的大多数支柱构件的宽度和/或厚度以及可扩张构件的远端部分。附近到近端部分中的最近端的细胞结构中的至少一个是具有足够的长度和灵活性的近端延伸的柔性线，用于导航曲折的脉管系统并且进入栓塞阻塞。在一个实施方案中，栓塞阻塞物检索装置通过输送导管的内腔被输送到栓塞阻塞物。

3. 发明授权

US08795345B2 Vascular and bodily duct treatment devices and methods 有权
标题翻译：血管和体管治疗装置及方法
公开(公告)号：US08795345B2
公开(公告)日：2014-08-05
申请号：US12573676
申请日：2009-10-05
申请人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Emily Vu , Kirk L. Pedersen , Craig L. Bonsignore , Elliot H. Sanders
发明人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Emily Vu , Kirk L. Pedersen , Craig L. Bonsignore , Elliot H. Sanders
IPC分类号： A61F2/06 , A61M29/00
CPC分类号： A61F2/90 , A61F2/91 , A61F2230/0008
摘要： A device including a self-expandable member having a proximal end portion, a main body portion and a distal end portion. Each of the self-expandable portions consists of a plurality of cell structures formed by intersecting strut members. In one implementation, at least one proximal cell structure in the proximal end portion has one or more struts that have a width and/or thickness greater than the width and/or thickness of the majority of strut members in the main body and distal end portions of the expandable member. Attached to at least one of the proximal-most cell structures in the proximal end portion is a proximally extending flexible wire having sufficient length and flexibility to navigate the tortuous vasculature of a patient. In another implementation, the device is delivered to the treatment site through the lumen of a delivery catheter.
摘要翻译：一种装置，包括具有近端部分，主体部分和远端部分的自扩张部件。每个自展开部分由通过相交的支柱构件形成的多个单元结构组成。在一个实施方案中，近端部分中的至少一个近端细胞结构具有一个或多个支柱，其具有大于主体中的大多数支柱构件的宽度和/或厚度的宽度和/或厚度，并且远端部分的可扩张构件。近端部分中的至少一个最近端的细胞结构附着有近端延伸的柔性丝，其具有足够的长度和柔性以导航患者的弯曲脉管系统。在另一个实施方案中，该装置通过输送导管的内腔被输送到治疗部位。

4. 发明申请

US20110009950A1 VASCULAR AND BODILY DUCT TREATMENT DEVICES AND METHODS 有权
标题翻译：血管和体液治疗装置及方法
公开(公告)号：US20110009950A1
公开(公告)日：2011-01-13
申请号：US12832857
申请日：2010-07-08
申请人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Emily Vu , Kirk L. Pedersen , Craig L. Bonsignore , Elliot H. Sanders
发明人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Emily Vu , Kirk L. Pedersen , Craig L. Bonsignore , Elliot H. Sanders
IPC分类号： A61F2/88 , A61F2/82
CPC分类号： A61F2/91 , A61B17/320725 , A61B17/32075 , A61B2017/22045 , A61B2017/320716 , A61F2/88 , A61F2/915 , A61F2/95 , A61F2002/91558 , A61F2220/005 , A61F2220/0058 , A61F2230/0008 , A61F2250/0059
摘要： A device including a self-expandable member having a proximal end portion and a main body portion. The self-expandable member is movable from a first delivery position to a second placement position, in the first delivery position the expandable member being in an unexpanded position and having a nominal first diameter and in the second position the expandable member being in a radially expanded position and having a second nominal diameter greater than the first nominal diameter for deployment within a vessel or duct of a patient. The expandable member includes a plurality of cell structures with the cell structures in the main body portion extending circumferentially around a longitudinal axis of the expandable member and the cell structures in the proximal end portion extending less than circumferentially around the longitudinal axis of the expandable member. In one implementation the cell structures have dimensional and material characteristics that result in about a −1.5N to a about a −3.5N overall reduction in radial force along the length of the expandable member per millimeter of expansion during about an initial 0.50 mm diametric range of expansion from the nominal diameter and that results in about a −0.10N to about a −0.50N overall reduction in radial force along the length of the expandable member per millimeter of expansion during subsequent diametric ranges of expansion.
摘要翻译：一种装置，包括具有近端部分和主体部分的自扩张部件。自膨胀构件可从第一输送位置移动到第二放置位置，在第一输送位置，可膨胀构件处于未膨胀位置并具有标称第一直径，并且在第二位置，可膨胀构件处于径向扩张并且具有大于第一公称直径的第二公称直径以用于部署在患者的血管或管道内。可扩张构件包括多个单元结构，其中主体部分中的单元结构围绕可扩展构件的纵向轴线周向延伸，并且近端部分中的单元结构沿着可扩展构件的纵向轴线周向延伸。在一个实施方案中，电池结构具有尺寸和材料特性，其在大约初始的0.50mm直径范围内导致沿着可膨胀元件的长度的每毫米膨胀的约-1.5N至约-3.5N的总体减小的径向力从公称直径膨胀，并且在随后的膨胀范围内，每毫米膨胀的沿着可膨胀构件的长度的整体减小约-0.10N至约-0.50N。

5. 发明申请

US20110009941A1 VASCULAR AND BODILY DUCT TREATMENT DEVICES AND METHODS 审中-公开
标题翻译：血管和体液治疗装置及方法
公开(公告)号：US20110009941A1
公开(公告)日：2011-01-13
申请号：US12643942
申请日：2009-12-21
申请人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Emily Vu , Kirk L. Pedersen , Craig L. Bonsignore , Elliot H. Sanders
发明人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Emily Vu , Kirk L. Pedersen , Craig L. Bonsignore , Elliot H. Sanders
IPC分类号： A61F2/84 , A61F2/82
CPC分类号： A61F2/915 , A61F2/01 , A61F2/013 , A61F2/88 , A61F2/91 , A61F2/95 , A61F2002/018 , A61F2002/825 , A61F2002/9528 , A61F2002/9534 , A61F2220/005 , A61F2220/0058 , A61F2230/0008 , A61F2250/0039
摘要： A device including a self-expandable member having a proximal end portion and a main body portion. Each of the self-expandable portions consists of a plurality of cell structures formed by intersecting strut members. In one implementation, at least one proximal cell structure in the proximal end portion has one or more struts that have a width and/or thickness greater than the width and/or thickness of the majority of strut members in the main body of the expandable member. In another implementation at least some of the intersecting strut members have a thickness to width ratio of greater than one. Attached to at least one of the proximal-most cell structures in the proximal end portion is a proximally extending flexible wire having sufficient length and flexibility to navigate the tortuous vasculature of a patient. In another implementation, the device is delivered to the treatment site through the lumen of a delivery catheter.
摘要翻译：一种装置，包括具有近端部分和主体部分的自扩张部件。每个自展开部分由通过相交的支柱构件形成的多个单元结构组成。在一个实施方案中，近端部分中的至少一个近端细胞结构具有一个或多个支柱，其具有大于可扩张构件主体中大部分支柱构件的宽度和/或厚度的宽度和/或厚度。在另一实施方式中，至少一些交叉支柱构件的厚度与宽度之比大于1。近端部分中的至少一个最近端的细胞结构附着有近端延伸的柔性丝，其具有足够的长度和柔性以导航患者的弯曲脉管系统。在另一个实施方案中，该装置通过输送导管的内腔被输送到治疗部位。

6. 发明申请

US20110009875A1 EMBOLIC OBSTRUCTION RETRIEVAL DEVICES AND METHODS 有权
标题翻译： EMBOLIC OBECT检索设备和方法
公开(公告)号：US20110009875A1
公开(公告)日：2011-01-13
申请号：US12499713
申请日：2009-07-08
申请人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Emily Vu , Kirk L. Pedersen , Craig L. Bonsignore , Elliot H. Sanders
发明人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Emily Vu , Kirk L. Pedersen , Craig L. Bonsignore , Elliot H. Sanders
IPC分类号： A61B17/22
CPC分类号： A61B17/221 , A61B2017/00867 , A61B2017/2215 , A61B2017/2217
摘要： An embolic obstruction retrieval device including a self-expandable member having a proximal end portion, a main body portion and a distal end portion. Each of the self-expandable portions consists of a plurality of cell structures formed by intersecting strut members. At least one proximal cell structure in the proximal end portion has one or more struts that have a width and/or thickness greater than the width and/or thickness of the majority of strut members in the main body and distal end portions of the expandable member. Attached to at least one of the proximal-most cell structures in the proximal end portion is a proximally extending flexible wire having sufficient length and flexibility to navigate the tortuous vasculature and access the embolic obstruction. In one implementation, the embolic obstruction retrieval device is delivered to the embolic obstruction through the lumen of a delivery catheter.
摘要翻译：一种栓塞性梗塞取出装置，其包括具有近端部分，主体部分和远端部分的自扩张部件。每个自展开部分由通过相交的支柱构件形成的多个单元结构组成。近端部分中的至少一个近端细胞结构具有一个或多个支柱，其具有大于主体中的大多数支柱构件的宽度和/或厚度的宽度和/或厚度，以及可扩张构件的远端部分。附近到近端部分中的最近端的细胞结构中的至少一个是具有足够的长度和灵活性的近端延伸的柔性线，用于导航曲折的脉管系统并且进入栓塞阻塞。在一个实施方案中，栓塞阻塞物检索装置通过输送导管的内腔被输送到栓塞阻塞物。

7. 发明授权

US08357178B2 Vascular and bodily duct treatment devices and methods 有权
标题翻译：血管和体管治疗装置及方法
公开(公告)号：US08357178B2
公开(公告)日：2013-01-22
申请号：US12832857
申请日：2010-07-08
申请人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Emily Vu , Kirk L. Pedersen , Craig L. Bonsignore , Elliot H. Sanders
发明人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Emily Vu , Kirk L. Pedersen , Craig L. Bonsignore , Elliot H. Sanders
IPC分类号： A61B17/22
CPC分类号： A61F2/91 , A61B17/320725 , A61B17/32075 , A61B2017/22045 , A61B2017/320716 , A61F2/88 , A61F2/915 , A61F2/95 , A61F2002/91558 , A61F2220/005 , A61F2220/0058 , A61F2230/0008 , A61F2250/0059
摘要： A clot retrieval device including a self-expandable member having a proximal end portion and a main body portion. The self-expandable member is expandable from a first delivery position to a second placement position. In the first delivery position the expandable member has a first overall diameter In one implementation the cell structures that form the self-expandable member have dimensional and material characteristics that result in about a −1.0N to about a −1.7N overall reduction in radial force along the length of the expandable member per millimeter of expansion during about an initial 0.50 mm diametric range of expansion from the first overall diameter and that results in about a −0.10N to about a −0.35N overall reduction in radial force along the length of the expandable member per millimeter of expansion during subsequent diametric ranges of expansion.
摘要翻译：一种凝块取回装置，包括具有近端部分和主体部分的自扩张部件。自膨胀构件可从第一输送位置扩展到第二放置位置。在第一输送位置，可膨胀构件具有第一总直径。在一个实施方式中，形成自膨胀构件的孔结构具有导致约-1.0N至约-1.7N的径向力的总体减小的尺寸和材料特性沿着可膨胀构件的每一毫米膨胀的长度，在从第一整体直径开始的约0.50mm的直径范围的大约初始的0.50mm范围内，并且导致约-0.10N至约-0.35N的沿径向力的总体减小在随后的膨胀范围内，可膨胀构件每毫米膨胀。

8. 发明申请

US20110184456A1 VASCULAR AND BODILY DUCT TREATMENT DEVICES AND METHODS 有权
标题翻译：血管和体液治疗装置及方法
公开(公告)号：US20110184456A1
公开(公告)日：2011-07-28
申请号：US13021364
申请日：2011-02-04
申请人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Elliot H. Sanders
发明人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Elliot H. Sanders
IPC分类号： A61F2/01
CPC分类号： A61B17/320725 , A61B17/32075 , A61B2017/22045 , A61B2017/320064 , A61B2017/320716 , A61F2/013 , A61F2/88 , A61F2/95 , A61F2002/91558 , A61F2250/0059
摘要： Devices including a self-expandable member having a proximal end portion and a main body portion. The self-expandable member is movable from a first delivery position to a second placement position, in the first delivery position the expandable member being in an unexpanded position and having a nominal first diameter and in the second position the expandable member being in a radially expanded position and having a second nominal diameter greater than the first nominal diameter for deployment within a vessel or duct of a patient. The expandable member includes a plurality of cell structures with the cell structures in the main body portion extending circumferentially around a longitudinal axis of the expandable member and the cell structures in the proximal end portion extending less than circumferentially around the longitudinal axis of the expandable member to form first and second peripheral rails that vary in width along their lengths.
摘要翻译：包括具有近端部分和主体部分的自扩张部件的装置。自膨胀构件可从第一输送位置移动到第二放置位置，在第一输送位置，可膨胀构件处于未膨胀位置并具有标称第一直径，并且在第二位置，可膨胀构件处于径向扩张并且具有大于第一公称直径的第二公称直径以用于部署在患者的血管或管道内。可扩张构件包括多个单元结构，其中主体部分中的单元结构围绕可扩展构件的纵向轴线周向延伸，并且近端部分中的单元结构沿着可扩展构件的纵向轴线的周向延伸至形成沿其长度宽度变化的第一和第二周边轨道。

9. 发明授权

US08357179B2 Vascular and bodily duct treatment devices and methods 有权
标题翻译：血管和体管治疗装置及方法
公开(公告)号：US08357179B2
公开(公告)日：2013-01-22
申请号：US13021364
申请日：2011-02-04
申请人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Elliot H. Sanders
发明人： Ryan M. Grandfield , Scott D. Wilson , John H. Miller , Elliot H. Sanders
IPC分类号： A61B17/22
CPC分类号： A61B17/320725 , A61B17/32075 , A61B2017/22045 , A61B2017/320064 , A61B2017/320716 , A61F2/013 , A61F2/88 , A61F2/95 , A61F2002/91558 , A61F2250/0059
摘要： Devices including a self-expandable member having a proximal end portion and a main body portion. The self-expandable member is movable from a first delivery position to a second placement position, in the first delivery position the expandable member being in an unexpanded position and having a nominal first diameter and in the second position the expandable member being in a radially expanded position and having a second nominal diameter greater than the first nominal diameter for deployment within a vessel or duct of a patient. The expandable member includes a plurality of cell structures with the cell structures in the main body portion extending circumferentially around a longitudinal axis of the expandable member and the cell structures in the proximal end portion extending less than circumferentially around the longitudinal axis of the expandable member to form first and second peripheral rails that vary in width along their lengths.
摘要翻译：包括具有近端部分和主体部分的自扩张部件的装置。自膨胀构件可从第一输送位置移动到第二放置位置，在第一输送位置，可膨胀构件处于未膨胀位置并具有标称第一直径，并且在第二位置，可膨胀构件处于径向扩张并且具有大于第一公称直径的第二公称直径以用于部署在患者的血管或管道内。可扩张构件包括多个单元结构，其中主体部分中的单元结构围绕可扩展构件的纵向轴线周向延伸，并且近端部分中的单元结构沿着可扩展构件的纵向轴线周向延伸，形成沿其长度宽度变化的第一和第二周边轨道。

10. 发明授权

US08529596B2 Vascular and bodily duct treatment devices and methods 有权
公开(公告)号：US08529596B2
公开(公告)日：2013-09-10
申请号：US13303890
申请日：2011-11-23
申请人： Ryan M. Grandfield , Scott D. Wilson , Elliot H. Sanders
发明人： Ryan M. Grandfield , Scott D. Wilson , Elliot H. Sanders
IPC分类号： A61B17/22
CPC分类号： A61B17/320725 , A61B17/32075 , A61B2017/22045 , A61B2017/2215 , A61B2017/320716 , A61F2/013 , A61F2002/91558
摘要： Devices including, but not limited to, a self-expandable member having a proximal end portion and a main body portion. The self-expandable member is movable from a first delivery position to a second placement position, in the first delivery position the expandable member being in an unexpanded position and having a nominal first diameter and in the second position the expandable member being in a radially expanded position and having a second nominal diameter greater than the first nominal diameter for deployment within a vessel or duct of a patient. The expandable member includes a plurality of cell structures with the cell structures in the main body portion extending circumferentially around a longitudinal axis of the expandable member and the cell structures in the proximal end portion extending less than circumferentially around the longitudinal axis of the expandable member to form first and second peripheral rails that vary in width along their lengths.

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