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1. 发明申请

US20050010093A1 Formulation and manipulation of databases of analyte and associated values 有权
标题翻译：分析物和相关值的数据库的制备和操作
公开(公告)号：US20050010093A1
公开(公告)日：2005-01-13
申请号：US10821055
申请日：2004-04-08
申请人： Russell Ford , Matthew Lesho , Russell Potts , Michael Tierney , Charles Wei
发明人： Russell Ford , Matthew Lesho , Russell Potts , Michael Tierney , Charles Wei
IPC分类号： G06F19/00 , A61B5/00
CPC分类号： G16H10/40 , G06F19/00 , G06F19/3456 , G16H10/60 , G16H40/63 , Y10S707/99945 , Y10S707/99948
摘要： The present invention relates to methods of formulating analyte data databases, the databases themselves, and methods of manipulating the same. In one aspect the present invention includes the formulation of analyte data points, derived data, and data attributes databases comprising data points collected using an analyte monitoring device capable of frequent monitoring of analyte concentrations or amounts. Such data points may comprise acquired data (e.g., values corresponding to analyte concentrations or amounts as measured by said analyte monitoring device). These data points are then associated with one or more relevant data attributes. The resulting databases may be manipulated to determine relationships among the components of the database.
摘要翻译：本发明涉及配制分析物数据数据库的方法，数据库本身及其操作方法。一方面，本发明包括分析物数据点，派生数据和数据属性数据库的配方，其包括使用能够频繁地监测分析物浓度或量的分析物监测装置收集的数据点。这样的数据点可以包括获取的数据（例如，对应于由所述分析物监测装置测量的分析物浓度或量的值）。然后将这些数据点与一个或多个相关数据属性相关联。可以操纵生成的数据库以确定数据库的组件之间的关系。

2. 发明申请

US20050049473A1 Methods for estimating analyte-related signals, microprocessors comprising programming to control performance of the methods, and analyte monitoring devices employing the methods 有权
标题翻译：用于估计分析物相关信号的方法，包括用于控制方法性能的编程的微处理器以及采用该方法的分析物监测装置
公开(公告)号：US20050049473A1
公开(公告)日：2005-03-03
申请号：US10963853
申请日：2004-10-13
申请人： Shashi Desai , Timothy Dunn , Matthew Lesho , Russell Potts , Janet Tamada , Charles Wei
发明人： Shashi Desai , Timothy Dunn , Matthew Lesho , Russell Potts , Janet Tamada , Charles Wei
IPC分类号： A61B5/00 , A61N1/30 , A61B5/05
CPC分类号： A61B5/1486 , A61B5/14532 , A61B5/1477 , A61N1/30
摘要： The present invention relates to methods to increase the number of analyte-related signals used to provide analyte measurement values, e.g., when two or more analyte-related signals are used to obtain a single analyte measurement value a “rolling” value based on the two or more signals can be employed. In another aspect, interpolation and/or extrapolation methods are used to estimate unusable, missing or error-associated analyte-related signals. Further, interpolation and extrapolation of values are employed in another aspect of the invention that reduces the incident of failed calibrations. Further, the invention relates to methods, which employ gradients and/or predictive algorithms, to provide an alert related to analyte values exceeding predetermined thresholds. The invention includes the above-described methods, one or more microprocessors programmed to execute the methods, one or more microprocessors programmed to execute the methods and control at least one sensing and/or sampling device, and monitoring systems employing the methods described herein.
摘要翻译：本发明涉及增加用于提供分析物测量值的分析物相关信号的数量的方法，例如当使用两个或更多个与分析物相关的信号来获得单个分析物测量值时，基于两个分析物相关信号的“滚动”值或更多的信号。在另一方面，内插和/或外插方法用于估计不可用，缺失或与误差相关的分析物相关信号。此外，在本发明的另一方面，采用了内插和外推值来减少校准失败的事件。此外，本发明涉及采用梯度和/或预测算法来提供与超过预定阈值的分析物值相关的警报的方法。本发明包括上述方法，被编程为执行方法的一个或多个微处理器，被编程为执行方法和控制至少一个感测和/或采样装置的一个或多个微处理器，以及采用本文描述的方法的监视系统。

3. 发明申请

US20100198196A1 Therapy Delivery Device Programming Tool 审中-公开
标题翻译：治疗传递设备编程工具
公开(公告)号：US20100198196A1
公开(公告)日：2010-08-05
申请号：US12363715
申请日：2009-01-30
申请人： Charles Wei
发明人： Charles Wei
IPC分类号： A61M5/172
CPC分类号： A61M5/14244 , A61M5/1723 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/52 , G06F19/3468 , G16H40/40 , G16H50/20
摘要： Methods and devices for providing programming tool for programming the initial and on-going operation of a therapy delivery device is provided. Embodiments include generating empirical rules for determining initial operating settings, applying the final empirical rules to a patient population, detecting a connection to a therapy delivery device, identifying the connected delivery device, receiving data download request from the delivery device. retrieving updated data associated with the connected delivery device; visualizing changes to the settings data of the device, and automatically transmitting the retrieved updated data to the delivery device.
摘要翻译：提供了用于提供用于编程治疗递送装置的初始和持续操作的编程工具的方法和装置。实施例包括生成用于确定初始操作设置的经验规则，将最终经验规则应用于患者群体，检测到治疗递送装置的连接，识别所连接的递送装置，从递送装置接收数据下载请求。检索与所连接的传送设备相关联的更新数据; 可视化对设备的设置数据的改变，并且将检索到的更新的数据自动发送到传送设备。

4. 发明授权

US09198623B2 Devices, systems, and methods related to analyte monitoring and management 有权
标题翻译：与分析物监测和管理相关的设备，系统和方法
公开(公告)号：US09198623B2
公开(公告)日：2015-12-01
申请号：US13091557
申请日：2011-04-21
申请人： Jonathan Fern , Mark P. Jesser , Lynn Dixon , Jai Karan , Charles Wei , Matthew T. Vogel , Tim S. Gasperak , Kim Cullen , Kim Ladin , Marc B. Taub , Gary A. Hayter
发明人： Jonathan Fern , Mark P. Jesser , Lynn Dixon , Jai Karan , Charles Wei , Matthew T. Vogel , Tim S. Gasperak , Kim Cullen , Kim Ladin , Marc B. Taub , Gary A. Hayter
IPC分类号： C12M1/34 , A61B5/00 , A61B5/145
CPC分类号： A61B5/14532 , A61B5/0022 , A61B5/14546 , A61B5/150358 , A61B5/72 , A61B5/742 , A61B5/743 , A61B5/7435 , A61B5/746 , A61B5/7475 , A61B2560/0295 , A61B2560/045 , G06F19/00 , G16H40/67
摘要： Analyte monitoring devices, systems, and methods are provided that relate to: enabling different application features on a data processing device for analyte monitoring devices with different analyte monitoring features; programming analyte monitoring devices in advance; personalizing an analyte monitoring device; graphically representing a remaining insulin level in a user body; and graphically representing analyte measurement related data for on-demand readings; protecting access to feature of an analyte monitoring device.
摘要翻译：提供了分析物监测装置，系统和方法，其涉及：在具有不同分析物监测特征的分析物监测装置的数据处理装置上实现不同的应用特征; 提前编程分析物监测装置; 个性化分析物监测装置; 以图形方式表示用户身体中的剩余胰岛素水平; 并以图形方式表示用于按需读数的分析物测量相关数据; 保护对分析物监测装置的特征的访问。

5. 发明授权

US08597274B2 Usability features for integrated insulin delivery system 有权
标题翻译：综合胰岛素输送系统的可用性特征
公开(公告)号：US08597274B2
公开(公告)日：2013-12-03
申请号：US12785144
申请日：2010-05-21
申请人： Mark Sloan , Marc B. Taub , Gary A. Hayter , Wesley Scott Harper , Erwin S. Budiman , Charles Wei
发明人： Mark Sloan , Marc B. Taub , Gary A. Hayter , Wesley Scott Harper , Erwin S. Budiman , Charles Wei
IPC分类号： A61M31/00
CPC分类号： A61M5/1723 , A61B5/14532 , A61B5/4839 , A61B5/746 , A61M5/142 , A61M2005/14296 , A61M2205/18 , A61M2205/3569 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3418 , G06F19/3456 , G08B21/0453 , G08B21/182 , G16H50/50
摘要： Various systems and methods for improving the usability of continuous glucose monitors and drug delivery pumps are described.
摘要翻译：描述了用于改善连续葡萄糖监测器和药物输送泵的可用性的各种系统和方法。

6. 发明授权

US08560082B2 Computerized determination of insulin pump therapy parameters using real time and retrospective data processing 有权
标题翻译：使用实时和回顾性数据处理计算机测定胰岛素泵治疗参数
公开(公告)号：US08560082B2
公开(公告)日：2013-10-15
申请号：US12363714
申请日：2009-01-30
申请人： Charles Wei
发明人： Charles Wei
IPC分类号： A61N1/00
CPC分类号： A61M5/142 , A61M5/172 , A61M2205/35 , A61M2205/50 , G06F19/00 , G06F19/3418 , G06F19/3468 , G16H40/63
摘要： Methods and devices for providing computerized adjustment to therapy parameters using real time and retrospective data processing is provided. Embodiments include receiving a respective data set from an infusion device and an analyte monitoring device for a predetermined time duration, user notification and reminder of the predetermined time duration, time synchronizing the received respective data set, detecting one or more marked data from the one or more respective data set received, establishing one or more filtering criteria to filter of retrospective or historical data based on certain condition, performing automated data analysis based on the detected one or more marked data or the data achieving certain predetermined condition to generate a modification to a therapy profile, generating and modifying rules for profile modification, and providing the generated modification to the therapy profile for reporting and transmission.
摘要翻译：提供了使用实时和回顾性数据处理为治疗参数提供计算机化调整的方法和装置。实施例包括在预定持续时间内从输注装置和分析物监测装置接收相应的数据集，用户通知和提醒预定持续时间，时间同步所接收的相应数据集，检测一个或多个标记的数据，建立一个或多个过滤标准以根据某些条件过滤回溯或历史数据，根据检测到的一个或多个标记数据执行自动数据分析，或者达到某一预定条件的数据，以生成对治疗简档，生成和修改配置文件修改规则，以及为治疗配置文件提供生成的修改以进行报告和传输。

7. 发明申请

US20110287528A1 Devices, Systems, and Methods Related to Analyte Monitoring and Management 有权
标题翻译：与分析物监测和管理相关的设备，系统和方法
公开(公告)号：US20110287528A1
公开(公告)日：2011-11-24
申请号：US13091557
申请日：2011-04-21
申请人： Jonathan Fern , Mark P. Jesser , Lynn Dixon , Jai Karan , Charles Wei , Matthew T. Vogel , Tim S. Gasperak , Kim Cullen , Kim Ladin , Marc B. Taub , Gary A. Hayter
发明人： Jonathan Fern , Mark P. Jesser , Lynn Dixon , Jai Karan , Charles Wei , Matthew T. Vogel , Tim S. Gasperak , Kim Cullen , Kim Ladin , Marc B. Taub , Gary A. Hayter
IPC分类号： C12M1/34
CPC分类号： A61B5/14532 , A61B5/0022 , A61B5/14546 , A61B5/150358 , A61B5/72 , A61B5/742 , A61B5/743 , A61B5/7435 , A61B5/746 , A61B5/7475 , A61B2560/0295 , A61B2560/045 , G06F19/00 , G16H40/67
摘要： Analyte monitoring devices, systems, and methods are provided that relate to: enabling different application features on a data processing device for analyte monitoring devices with different analyte monitoring features; programming analyte monitoring devices in advance; personalizing an analyte monitoring device; graphically representing a remaining insulin level in a user body; and graphically representing analyte measurement related data for on-demand readings; protecting access to feature of an analyte monitoring device.
摘要翻译：提供了分析物监测装置，系统和方法，其涉及：在具有不同分析物监测特征的分析物监测装置的数据处理装置上实现不同的应用特征; 提前编程分析物监测装置; 个性化分析物监测装置; 以图形方式表示用户身体中的剩余胰岛素水平; 并以图形方式表示用于按需读数的分析物测量相关数据; 保护对分析物监测装置的特征的访问。

8. 发明申请

US20110166875A1 SYSTEM AND METHOD FOR MANAGING MEDICAL DATA AND FACILITATING REIMBURSEMENT FOR HEALTH CARE 审中-公开
标题翻译：用于管理医疗数据和促进健康护理的系统和方法
公开(公告)号：US20110166875A1
公开(公告)日：2011-07-07
申请号：US12985233
申请日：2011-01-05
申请人： Gary A. Hayter , Charles Wei , Marc B. Taub
发明人： Gary A. Hayter , Charles Wei , Marc B. Taub
IPC分类号： G06Q50/00 , G06Q10/00
CPC分类号： G06Q50/22 , G06Q10/10
摘要： System and method receive medical data of a patient having a disease afflicted health condition for processing and analysis of that data. Software installed on a health care provider's computer for processing the medical data includes a GUI reimbursement window that informs the HCP of reimbursement possibilities for analysis of the data and counseling of the patient. The reimbursement window also includes hyperlinks and may also include codes for insurance claims. Lists of reimbursement entities, pre-authorization instructions, coding instructions, and contacts may all be included and may be personalized for a particular patient. In one case, a complete bill is created and submitted to an insurance entity. In another, a patient data base is created so that the reimbursement window can inform the HCP of patient analysis frequency, which may affect reimbursement.
摘要翻译：系统和方法接收具有疾病影响的健康状况的患者的医疗数据，用于处理和分析该数据。在医疗保健提供者的计算机上安装的用于处理医疗数据的软件包括GUI报销窗口，其向HCP通知用于分析患者的数据和咨询的可能性。报销窗口还包括超链接，还可能包括保险索赔代码。报销实体，预授权指令，编码说明和联系人的列表可以全部包括在内，并且可以针对特定患者进行个性化。在一种情况下，创建完整的帐单并提交给保险实体。另一方面，创建了一个病人数据库，以便报销窗口可以向HCP通知患者分析频率，这可能会影响报销。

9. 发明申请

US20110021898A1 REAL TIME MANAGEMENT OF DATA RELATING TO PHYSIOLOGICAL CONTROL OF GLUCOSE LEVELS 有权
标题翻译：关于葡萄糖水平生理控制的数据的实时管理
公开(公告)号：US20110021898A1
公开(公告)日：2011-01-27
申请号：US12842838
申请日：2010-07-23
申请人： Charles Wei , Gary A. Hayter
发明人： Charles Wei , Gary A. Hayter
IPC分类号： A61B5/145
CPC分类号： G06F17/30598 , A61B5/14532 , A61B5/746 , A61M5/1723 , A61M2005/14208 , A61M2205/3592 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3418 , G16H50/20 , G16H50/30 , G16H50/50
摘要： Continuous glucose monitoring (CGM) data and insulin delivery data are used to generate more reliable projected alarms related to a projected glucose levels. A memory stores endogenous data related to measurements of glucose level in a patient, and also stores exogenous data, such as insulin on board, both of which are used by a processor to create projected alarms. Profiles of CGM data are created for use in tuning patient-specific insulin data, such at basal rate, carb ratio, and insulin sensitivity. A processor searches for patterns in the data profiles and if found, recommended changes to patient-specific insulin data are provided to permit more accurate control over a patient's glucose levels.
摘要翻译：连续葡萄糖监测（CGM）数据和胰岛素输送数据用于产生与预计葡萄糖水平相关的更可靠的预测报警。存储器存储与患者中葡萄糖水平的测量相关的内源性数据，并且还存储外部数据，例如船上的胰岛素，两者均由处理器用于产生预测的报警。创建CGM数据的配置文件用于调整患者特异性胰岛素数据，例如基础速率，碳水化合物比例和胰岛素敏感性。处理器搜索数据简档中的模式，并且如果发现，则提供对患者特异性胰岛素数据的推荐改变以允许对患者的葡萄糖水平的更准确的控制。

10. 发明申请

US20100298765A1 SAFETY FEATURES FOR INTEGRATED INSULIN DELIVERY SYSTEM 有权
标题翻译：一体化胰岛素输送系统的安全性能
公开(公告)号：US20100298765A1
公开(公告)日：2010-11-25
申请号：US12785104
申请日：2010-05-21
申请人： Erwin S. Budiman , Gary A. Hayter , Nathan Crouther , Marc B. Taub , Wesley Scott Harper , Charles Wei
发明人： Erwin S. Budiman , Gary A. Hayter , Nathan Crouther , Marc B. Taub , Wesley Scott Harper , Charles Wei
IPC分类号： A61M5/168
CPC分类号： A61M5/1723 , A61B5/14532 , A61B5/1495 , A61B5/4839 , A61B2562/0295 , A61M2005/14208 , A61M2005/14296 , A61M2205/3569 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3468
摘要： Safety features are applied to an integrated insulin delivery system to enhance safety while accounting for glucose sensor bias and calibration errors. One safety feature includes comparisons of calibrations of the sensor to nominal sensitivity and taking action, such as limiting insulin delivery or taking a further calibration of the sensor. In another feature, an automatic resumption of a basal delivery rate is programmed into the delivery device to avoid the possibility of complete loss of delivery of insulin in the event that communication with the delivery device is disrupted. Other features include steps taken to avoid hypoglycemia in the event that the sensor is negatively biased.
摘要翻译：安全功能应用于集成的胰岛素输送系统，以增强安全性，同时考虑到葡萄糖传感器偏差和校准误差。一个安全特征包括将传感器的校准与标称灵敏度进行比较，并采取行动，例如限制胰岛素输送或进一步校准传感器。在另一特征中，将自动恢复基本递送速率编程到递送设备中，以避免在与递送设备的通信被中断的情况下胰岛素完全丢失的可能性。其他功能包括在传感器受到负偏压的情况下避免低血糖的步骤。

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