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1. 发明授权

US08140143B2 Washable wearable biosensor 有权
标题翻译：可洗涤可佩戴的生物传感器
公开(公告)号：US08140143B2
公开(公告)日：2012-03-20
申请号：US12386348
申请日：2009-04-16
申请人： Rosalind W. Picard , Clayton J. Williams , Richard Ribon Fletcher , Hoda Eydgahi , Ming-Zher Poh , Oliver Orion Wilder-Smith , Kyunghee Kim , Kelly Dobson , Jackie Chia-Hsun Lee
发明人： Rosalind W. Picard , Clayton J. Williams , Richard Ribon Fletcher , Hoda Eydgahi , Ming-Zher Poh , Oliver Orion Wilder-Smith , Kyunghee Kim , Kelly Dobson , Jackie Chia-Hsun Lee
IPC分类号： A61B5/04
CPC分类号： A61B5/0022 , A61B5/015 , A61B5/0531 , A61B5/1455 , A61B5/6804 , A61B5/6806 , A61B5/6807 , G06F19/00 , G16H40/67
摘要： A washable, wearable biosensor that can gather sensor data, communicate the sensed data by wireless protocols, and permits the analysis of sensed data in real-time as a person goes about their normal lifestyle activities. The biosensor can be worn in multiple positions, can be put on or removed quickly without having to apply or remove gels and adhesives, and provides a snug, comfortable fit to gather data with minimal motion artifacts. The textile, wearable device can support integrated photoplethysmography, skin conductance, motion, and temperature sensors in a small wearable package. The supported sensors may be coupled to utilization devices by channel-sharing wireless protocols to enable the transmission of data from multiple users and multiple sensors (e.g. both sides of body, wrists or hands and feet, or multiple people). An on-board processor, or the receiving utilization device, can map patterns of the physiological and motion data to signals or alerts such as a likely seizure, drug craving, or other states that the wearer may exhibit or experience. The sensor data may be sent by wireless transmission and received by a mobile phone or other personal digital device, a computer, a favorite toy, or another wearable device. The sensors may include multiple photoplethysmographs and/or one or more EDAs which perform a time-domain measurement of skin conductance.
摘要翻译：一种可洗涤，可穿戴的生物传感器，可以收集传感器数据，通过无线协议传达感测的数据，并允许实时分析感测数据，因为人们正视其正常的生活方式活动。生物传感器可以佩戴在多个位置，可以快速放置或取出，而无需使用或去除凝胶和粘合剂，并提供舒适，舒适的配合，以最少的运动伪影收集数据。纺织，可穿戴设备可以支持集成的光电体积描记术，皮肤电导，运动和温度传感器，在小型可穿戴包装中。支持的传感器可以通过信道共享无线协议耦合到利用装置，以便能够传输来自多个用户和多个传感器（例如身体，手腕或手，脚或多个人的两侧）的数据。车载处理器或接收利用装置可以将生理和运动数据的图案映射到诸如可能的发作，药物渴望或佩戴者可能展示或经历的其他状态的信号或警报。传感器数据可以通过无线传输发送并由移动电话或其他个人数字设备，计算机，喜爱的玩具或其他可穿戴设备接收。传感器可以包括执行皮肤电导的时域测量的多个光体积描记器和/或一个或多个EDA。

2. 发明申请

US20100268056A1 Washable wearable biosensor 有权
标题翻译：可洗涤可佩戴的生物传感器
公开(公告)号：US20100268056A1
公开(公告)日：2010-10-21
申请号：US12386348
申请日：2009-04-16
申请人： Rosalind W. Picard , Clayton J. Williams , Richard Ribon Fletcher , Hoda Eydgahi , Ming-Zher Poh , Oliver Orion Wilder-Smith , Kyunghee Kim , Kelly Dobson , Jackie Chia-Hsun Lee
发明人： Rosalind W. Picard , Clayton J. Williams , Richard Ribon Fletcher , Hoda Eydgahi , Ming-Zher Poh , Oliver Orion Wilder-Smith , Kyunghee Kim , Kelly Dobson , Jackie Chia-Hsun Lee
IPC分类号： A61B5/04 , A61B5/00
CPC分类号： A61B5/0022 , A61B5/015 , A61B5/0531 , A61B5/1455 , A61B5/6804 , A61B5/6806 , A61B5/6807 , G06F19/00 , G16H40/67
摘要： A washable, wearable biosensor that can gather sensor data, communicate the sensed data by wireless protocols, and permits the analysis of sensed data in real-time as a person goes about their normal lifestyle activities. The biosensor can be worn in multiple positions, can be put on or removed quickly without having to apply or remove gels and adhesives, and provides a snug, comfortable fit to gather data with minimal motion artifacts. The textile, wearable device can support integrated photoplethysmography, skin conductance, motion, and temperature sensors in a small wearable package. The supported sensors may be coupled to utilization devices by channel-sharing wireless protocols to enable the transmission of data from multiple users and multiple sensors (e.g. both sides of body, wrists or hands and feet, or multiple people). An on-board processor, or the receiving utilization device, can map patterns of the physiological and motion data to signals or alerts such as a likely seizure, drug craving, or other states that the wearer may exhibit or experience. The sensor data may be sent by wireless transmission and received by a mobile phone or other personal digital device, a computer, a favorite toy, or another wearable device. The sensors may include multiple photoplethysmographs and/or one or more EDAs which perform a time-domain measurement of skin conductance
摘要翻译：一种可洗涤，可穿戴的生物传感器，可以收集传感器数据，通过无线协议传达感测数据，并允许实时分析感测数据，因为人们正视其正常的生活方式活动。生物传感器可以佩戴在多个位置，可以快速放置或取出，而无需使用或去除凝胶和粘合剂，并提供舒适，舒适的配合，以最少的运动伪影收集数据。纺织，可穿戴设备可以支持集成的光电体积描记术，皮肤电导，运动和温度传感器，在小型可穿戴包装中。支持的传感器可以通过信道共享无线协议耦合到利用装置，以便能够传输来自多个用户和多个传感器（例如身体，手腕或手，脚或多个人的两侧）的数据。车载处理器或接收利用装置可以将生理和运动数据的图案映射到诸如可能的发作，药物渴望或佩戴者可能展示或经历的其他状态的信号或警报。传感器数据可以通过无线传输发送并由移动电话或其他个人数字设备，计算机，喜爱的玩具或其他可穿戴设备接收。传感器可以包括执行皮肤电导的时域测量的多个光体积描记器和/或一个或多个EDA

3. 发明申请

US20110251493A1 METHOD AND SYSTEM FOR MEASUREMENT OF PHYSIOLOGICAL PARAMETERS 审中-公开
标题翻译：生理参数测量方法与系统
公开(公告)号：US20110251493A1
公开(公告)日：2011-10-13
申请号：US13048965
申请日：2011-03-16
申请人： Ming-Zher Poh , Daniel J. McDuff , Rosalind W. Picard
发明人： Ming-Zher Poh , Daniel J. McDuff , Rosalind W. Picard
IPC分类号： A61B6/00 , G06K9/00
CPC分类号： G06K9/00255 , A61B5/0205 , A61B5/02405 , A61B2576/00 , G06K9/624
摘要： Method and system for measuring physiological parameters. The method includes capturing a sequence of images of a human face and identifying the location of the face in a frame of the video and establishing a region of interest including the face. Pixels are separated in the region of interest in a frame into at least two channel values forming raw traces over time. The raw traces are decomposed into at least two independent source signals. At least one of the source signals is processed to obtain a physiological parameter.
摘要翻译：测量生理参数的方法和系统。该方法包括捕获人脸图像的序列，并且识别在视频的帧中的脸部的位置并建立包括脸部的感兴趣区域。将像素在帧中的感兴趣区域中分离为形成随时间变化的原始迹线的至少两个通道值。原始轨迹分解为至少两个独立的源信号。处理至少一个源信号以获得生理参数。

4. 发明授权

US08795173B2 Methods and apparatus for assessment of atypical brain activity 有权
标题翻译：用于评估非典型脑活动的方法和装置
公开(公告)号：US08795173B2
公开(公告)日：2014-08-05
申请号：US13474704
申请日：2012-05-17
申请人： Ming-Zher Poh , Rosalind Picard
发明人： Ming-Zher Poh , Rosalind Picard
IPC分类号： A61B5/00 , A61B5/024 , A61B5/11 , A61B5/053
CPC分类号： A61B5/4094 , A61B5/02405 , A61B5/0533 , A61B5/1118 , A61B5/7275 , G06F19/00
摘要： In exemplary implementations of this invention, sensor measurements are taken before, during and after an epileptiform seizure of a human. The sensors measure electrodermal activity (EDA) and heart rate variability (HRV) of the human.The EDA and HRV measurements are used to assess sympathetic activity and parasympathetic activity, respectively. More particularly, in the case of HRV measurements, HF power is used to assess parasympathetic innervation of the heart. HF power is the power of the high frequency (e.g. 0.15 to 0.4 Hz) spectral component of the RRI signal.One or more processors analyze the sensor data to calculate the magnitude of a post-ictal autonomic disturbance. Based on that calculated magnitude, the processors assess the severity of the seizure.A wrist-worn sensor may take long-term, continuous EDA and motion measurements. The processors may analyze these measurements to detect the onset of a tonic-clonic seizure.
摘要翻译：在本发明的示例性实施方案中，在人的癫痫发作之前，期间和之后进行传感器测量。传感器测量人体的皮肤活性（EDA）和心率变异性（HRV）。 EDA和HRV测量分别用于评估交感神经活动和副交感神经活动。更特别地，在HRV测量的情况下，使用HF功率来评估心脏的副交感神经支配。 HF功率是RRI信号的高频（例如0.15至0.4Hz）频谱分量的功率。一个或多个处理器分析传感器数据以计算发明后自主神经障碍的大小。根据该计算的数量，处理者评估缉获的严重程度。手腕式传感器可以进行长期，连续的EDA和运动测量。处理器可以分析这些测量以检测强直阵挛发作的发作。

5. 发明申请

US20120296175A1 Methods and apparatus for assessment of atypical brain activity 有权
标题翻译：用于评估非典型脑活动的方法和装置
公开(公告)号：US20120296175A1
公开(公告)日：2012-11-22
申请号：US13474704
申请日：2012-05-17
申请人： Ming-Zher Poh , Rosalind Picard
发明人： Ming-Zher Poh , Rosalind Picard
IPC分类号： A61B5/0205 , A61B5/11 , A61B5/053
CPC分类号： A61B5/4094 , A61B5/02405 , A61B5/0533 , A61B5/1118 , A61B5/7275 , G06F19/00
摘要： In exemplary implementations of this invention, sensor measurements are taken before, during and after an epileptiform seizure of a human. The sensors measure electrodermal activity (EDA) and heart rate variability (HRV) of the human.The EDA and HRV measurements are used to assess sympathetic activity and parasympathetic activity, respectively. More particularly, in the case of HRV measurements, HF power is used to assess parasympathetic innervation of the heart. HF power is the power of the high frequency (e.g. 0.15 to 0.4 Hz) spectral component of the RRI signal.One or more processors analyze the sensor data to calculate the magnitude of a post-ictal autonomic disturbance. Based on that calculated magnitude, the processors assess the severity of the seizure.A wrist-worn sensor may take long-term, continuous EDA and motion measurements. The processors may analyze these measurements to detect the onset of a tonic-clonic seizure.
摘要翻译：在本发明的示例性实施方案中，在人的癫痫发作之前，期间和之后进行传感器测量。传感器测量人体的皮肤活性（EDA）和心率变异性（HRV）。 EDA和HRV测量分别用于评估交感神经活动和副交感神经活动。更特别地，在HRV测量的情况下，使用HF功率来评估心脏的副交感神经支配。 HF功率是RRI信号的高频（例如0.15至0.4Hz）频谱分量的功率。一个或多个处理器分析传感器数据以计算发明后自主神经障碍的大小。根据该计算的数量，处理者评估缉获的严重程度。手腕式传感器可以进行长期，连续的EDA和运动测量。处理器可以分析这些测量以检测强直阵挛发作的发作。

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