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1. 发明授权

US07717936B2 Device for loading an embolic protection filter into a catheter 有权
标题翻译：用于将栓塞保护过滤器装载到导管中的装置
公开(公告)号：US07717936B2
公开(公告)日：2010-05-18
申请号：US11408732
申请日：2006-04-18
申请人： Ronan Keating , David Vale , John Neilan
发明人： Ronan Keating , David Vale , John Neilan
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61F2002/011 , A61F2230/0006
摘要： A transvascular embolic protection system for safely capturing and retaining embolic material released during an interventional procedure comprises an embolic protection device (1) and a delivery catheter (2) for delivery of the embolic protection device (1) to a desired location in the vascular system. A pack (4) is provided to safely store and prepare the embolic protection system for use. The pack (4) comprises a tray (5) with a channel (6) extending in a looped configuration around the tray (5) for receiving the delivery catheter (2). A loading device (7) is mounted in the tray (5) adjacent to the delivery catheter (2). The embolic protection device (1) is mounted in an expanded configuration in a well (90) in the tray (5). A pushing device (8) for loading the collapsible embolic protection device (1) into the delivery catheter (2) is mounted in the tray (5) adjacent to the embolic protection device (1).
摘要翻译：一种用于安全捕获和保持在介入手术期间释放的栓塞物质的血管内栓塞保护系统，包括用于将栓塞保护装置（1）输送到血管系统中所需位置的栓塞保护装置（1）和输送导管（2）。提供一包（4）以安全地存储和准备使用的栓塞保护系统。所述包装盒（4）包括托盘（5），所述托盘（5）具有围绕所述托盘（5）以环形构造延伸的通道（6），用于接纳所述输送导管（2）。装载装置（7）安装在邻近输送导管（2）的托盘（5）中。栓塞保护装置（1）以扩展构造安装在托盘（5）中的井（90）中。用于将可折叠栓塞保护装置（1）装载到输送导管（2）中的推动装置（8）安装在邻近栓塞保护装置（1）的托盘（5）中。

2. 发明申请

US20060293705A1 Embolic protection device 有权
标题翻译：栓塞保护装置
公开(公告)号：US20060293705A1
公开(公告)日：2006-12-28
申请号：US11406822
申请日：2006-04-18
申请人： John Neilan , Ronan Keating , David Vale
发明人： John Neilan , Ronan Keating , David Vale
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61B2017/22051 , A61B2017/22067 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0067
摘要： An embolic protection device (2000) comprises a collapsible filter body (102), a filter support (103) for supporting the filter body (102), and a tubular member (108) to which the filter support (103) is mounted. The filter support (103) comprises two round wires (116). Each wire (116) has a “M”-shaped curve (120) in the wire (116) which acts as a strain distributing linking element. In an extended configuration, the concave portion of each curve (120) faces longitudinally in the distal direction. In a collapsed configuration, the concave portion faces radially inwardly towards the tubular member (108) and wraps around part of the tubular member (108) to define a compact, low-profile filter support (103). Tethers (500, 501) extend between the curves (120) and a sleeve (201) slidably mounted to the tubular member (108). The distal end of each tether (500, 501) is fixedly attached to the sleeve (201) and to the filter body (102). The sleeve (201) is slidable over the tubular member (108) between a pair of stops.
摘要翻译：栓塞保护装置（2000）包括可折叠过滤器主体（102），用于支撑过滤器本体（102）的过滤器支撑件（103）和安装过滤器支撑件（103）的管状构件（108）。过滤器支撑件（103）包括两根圆形线（116）。每根线（116）在线（116）中具有“M”形曲线（120），其作为应变分布连接元件。在延伸构造中，每个曲线（120）的凹部在远端方向上面向纵向。在折叠构造中，凹部朝向管状构件（108）径向向内，并且围绕管状构件（108）的一部分缠绕以限定紧凑的低轮廓过滤器支撑件（103）。系带（500,501）在曲线（120）和可滑动地安装到管状构件（108）的套筒（201）之间延伸。每个系绳（500,501）的远端固定地连接到套筒（201）和过滤器主体（102）上。套筒（201）可在一对止动件之间在管状构件（108）上滑动。

3. 发明授权

US08057505B2 Embolic protection device 有权
标题翻译：栓塞保护装置
公开(公告)号：US08057505B2
公开(公告)日：2011-11-15
申请号：US11406822
申请日：2006-04-18
申请人： John Neilan , Ronan Keating , David Vale
发明人： John Neilan , Ronan Keating , David Vale
IPC分类号： A61M29/00 , A61F2/06
CPC分类号： A61F2/013 , A61B2017/22051 , A61B2017/22067 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0067
摘要： An embolic protection device (2000) comprises a collapsible filter body (102), a filter support (103) for supporting the filter body (102), and a tubular member (108) to which the filter support (103) is mounted. The filter support (103) comprises two round wires (116). Each wire (116) has a “M”-shaped curve (120) in the wire (116) which acts as a strain distributing linking element. In an extended configuration, the concave portion of each curve (120) faces longitudinally in the distal direction. In a collapsed configuration, the concave portion faces radially inwardly towards the tubular member (108) and wraps around part of the tubular member (108) to define a compact, low-profile filter support (103). Tethers (500, 501) extend between the curves (120) and a sleeve (201) slidably mounted to the tubular member (108). The distal end of each tether (500, 501) is fixedly attached to the sleeve (201) and to the filter body (102). The sleeve (201) is slidable over the tubular member (108) between a pair of stops.
摘要翻译：栓塞保护装置（2000）包括可折叠过滤器主体（102），用于支撑过滤器本体（102）的过滤器支撑件（103）和安装过滤器支撑件（103）的管状构件（108）。过滤器支撑件（103）包括两根圆形线（116）。每根线（116）在线（116）中具有“M”形曲线（120），其作为应变分布连接元件。在延伸构造中，每个曲线（120）的凹部在远端方向上面向纵向。在折叠构造中，凹部朝向管状构件（108）径向向内，并且围绕管状构件（108）的一部分缠绕以限定紧凑的低轮廓过滤器支撑件（103）。系带（500,501）在曲线（120）和可滑动地安装到管状构件（108）的套筒（201）之间延伸。每个系绳（500,501）的远端固定地连接到套筒（201）和过滤器主体（102）上。套筒（201）可在一对止动件之间在管状构件（108）上滑动。

4. 发明申请

US20110034951A1 DEVICE FOR LOADING AN EMBOLIC PROTECTION FILTER INTO A CATHETER 审中-公开
标题翻译：用于将防爆过滤器装入导管的装置
公开(公告)号：US20110034951A1
公开(公告)日：2011-02-10
申请号：US12772463
申请日：2010-05-03
申请人： Ronan Keating , David Vale , John NEILAN
发明人： Ronan Keating , David Vale , John NEILAN
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61F2002/011 , A61F2230/0006
摘要： A device for loading an embolic protection filter into a catheter including a loading member for collapsing an embolic protection filter, wherein an outlet of the loading member is configured to be aligned with an inlet of a catheter extending along at least part of an exterior surface of the catheter for loading of the collapsed embolic protection filter into the catheter. The loading member may have a passageway extending therethrough, through which an embolic protection filter may be passed to collapse the embolic protection filter. The outlet of the loading member may include an outlet of the passageway that is at least partially funnel-shaped. The loading member may include a tubular part extendable along part of an exterior surface of a catheter, the outlet of the loading member being provided at an end of the tubular part.
摘要翻译：一种用于将栓塞保护过滤器装载到导管中的装置，包括用于塌陷栓塞保护过滤器的装载构件，其中装载构件的出口构造成与沿着至少部分外表面延伸的导管的入口对准用于将塌陷的栓塞保护过滤器装载到导管中的导管。装载构件可以具有穿过其中的通道，栓塞保护过滤器可以通过该通道通过以使栓塞保护过滤器收缩。装载构件的出口可以包括至少部分漏斗形的通道出口。装载构件可以包括可沿着导管的外表面的一部分延伸的管状部分，装载构件的出口设置在管状部分的端部。

5. 发明申请

US20070005102A1 Device for loading an embolic protection filter into a catheter 有权
标题翻译：用于将栓塞保护过滤器装载到导管中的装置
公开(公告)号：US20070005102A1
公开(公告)日：2007-01-04
申请号：US11408732
申请日：2006-04-18
申请人： Ronan Keating , David Vale , John Neilan
发明人： Ronan Keating , David Vale , John Neilan
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61F2002/011 , A61F2230/0006
摘要： A transvascular embolic protection system for safely capturing and retaining embolic material released during an interventional procedure comprises an embolic protection device (1) and a delivery catheter (2) for delivery of the embolic protection device (1) to a desired location in the vascular system. A pack (4) is provided to safely store and prepare the embolic protection system for use. The pack (4) comprises a tray (5) with a channel (6) extending in a looped configuration around the tray (5) for receiving the delivery catheter (2). A loading device (7) is mounted in the tray (5) adjacent to the delivery catheter (2). The embolic protection device (1) is mounted in an expanded configuration in a well (90) in the tray (5). A pushing device (8) for loading the collapsible embolic protection device (1) into the delivery catheter (2) is mounted in the tray (5) adjacent to the embolic protection device (1).
摘要翻译：一种用于安全捕获和保持在介入手术期间释放的栓塞物质的血管内栓塞保护系统，包括用于将栓塞保护装置（1）输送到血管系统中所需位置的栓塞保护装置（1）和输送导管（2）。提供一包（4）以安全地存储和准备使用的栓塞保护系统。所述包装盒（4）包括托盘（5），所述托盘（5）具有围绕所述托盘（5）以环形构造延伸的通道（6），用于接纳所述输送导管（2）。装载装置（7）安装在邻近输送导管（2）的托盘（5）中。栓塞保护装置（1）以扩展构造安装在托盘（5）中的井（90）中。用于将可折叠栓塞保护装置（1）装载到输送导管（2）中的推动装置（8）安装在邻近栓塞保护装置（1）的托盘（5）中。

6. 发明申请

US20070173883A1 Embolic protection system 审中-公开
标题翻译：栓塞保护系统
公开(公告)号：US20070173883A1
公开(公告)日：2007-07-26
申请号：US11508805
申请日：2006-08-23
申请人： Martin Keegan , Eamon Brady , Brendan Casey , David Vale , John Neilan , Morgan Tierney
发明人： Martin Keegan , Eamon Brady , Brendan Casey , David Vale , John Neilan , Morgan Tierney
IPC分类号： A61M29/00
CPC分类号： A61F2/0095 , A61B17/221 , A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2002/9522 , A61F2230/0006 , A61F2230/0067
摘要： An embolic protection filter for deployment in a vasculature, the filter having an inlet end and an outlet end, the inlet end having one or more inlet openings sized to allow blood and embolic material enter the filter, and the outlet end of the filter having a plurality of outlet openings sized to allow through passage of blood but to retain undesired embolic material within the filter. The filter is movable between a collapsed configuration for movement through a vasculature, and an outwardly extended configuration for deployment in a vasculature. The filter at least in the collapsed configuration was a guidewire lumen defined at least partially therethrough for passing the filter over a guidewire. The guidewire lumen is defined by a lumen-defining member which is spaced proximally of the distal end of the filter.
摘要翻译：一种用于部署在脉管系统中的栓塞保护过滤器，所述过滤器具有入口端和出口端，所述入口端具有一个或多个入口开口，其尺寸设计成允许血液和栓塞物质进入过滤器，并且所述过滤器的出口端具有多个出口开口尺寸允许通过血液通过，但是将不期望的栓塞材料保持在过滤器内。过滤器可在折叠构型之间移动，以便通过脉管系统移动，以及用于部署在脉管系统中的向外延伸的配置。至少在折叠构造中的过滤器是至少部分地穿过其中的导丝腔，用于使过滤器穿过导丝。导丝管腔由位于过滤器的远端的近端间隔开的内腔限定构件限定。

7. 发明授权

US07144408B2 Embolic protection system 有权
标题翻译：栓塞保护系统
公开(公告)号：US07144408B2
公开(公告)日：2006-12-05
申请号：US10379434
申请日：2003-03-05
申请人： Martin Keegan , Eamon Brady , Brendan Casey , David Vale , John Neilan , Morgan Tierney
发明人： Martin Keegan , Eamon Brady , Brendan Casey , David Vale , John Neilan , Morgan Tierney
IPC分类号： A61M29/00
CPC分类号： A61M25/104 , A61B17/221 , A61B2017/22035 , A61B2017/2212 , A61F2/01 , A61F2/013 , A61F2/958 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/0008 , A61F2230/0067 , A61F2230/008
摘要： An embolic protection filter system comprises a collapsible embolic protection filter 62 having a collapsed configuration for delivery of the filter, and a deployed configuration and a temporary lumen defining member 60. The lumen defining member 60 is used for loading a filter-containing delivery catheter 63 onto a guidewire 65. After loading, the member 60 can be removed by pulling on a tab 61.
摘要翻译：栓塞保护过滤器系统包括具有用于输送过滤器的折叠构造的可折叠栓塞保护过滤器62以及展开构造和临时腔室限定构件60。腔限定构件60用于将含过滤剂的输送导管63装载到导丝65上。装载后，可以通过拉动翼片61来移除构件60。

8. 发明申请

US20060122644A1 Support frame for an embolic protection device 有权
公开(公告)号：US20060122644A1
公开(公告)日：2006-06-08
申请号：US11166803
申请日：2005-06-27
申请人： Eamon Brady , David Vale , Ronald Kelly , John Neilan , Steven Horan , Gerard Rabitte , Gerry McCaffrey
发明人： Eamon Brady , David Vale , Ronald Kelly , John Neilan , Steven Horan , Gerard Rabitte , Gerry McCaffrey
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61B2017/2212 , A61B2017/2215 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0093
摘要： An embolic protection device comprises a collapsible filter body and a filter support for the filter body. The filter support comprises a support frame defined by at least two wire segments having terminations. The terminations of adjacent segments are fixed relative to one another and extend generally parallel in a bifilar manner for enhanced trackability and flexibility.

9. 发明授权

US06918921B2 Support frame for an embolic protection device 有权
标题翻译：用于栓塞保护装置的支撑框架
公开(公告)号：US06918921B2
公开(公告)日：2005-07-19
申请号：US10326891
申请日：2002-12-23
申请人： Eamon Brady , David Vale , Ronald Kelly , John Neilan , Steven Horan , Gerard Rabitte , Gerry McCaffrey
发明人： Eamon Brady , David Vale , Ronald Kelly , John Neilan , Steven Horan , Gerard Rabitte , Gerry McCaffrey
IPC分类号： A61F2/01 , A61M29/00
CPC分类号： A61F2/01 , A61B2017/2212 , A61B2017/2215 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0093
摘要： An embolic protection device comprises a collapsible filter element for delivery through a vascular system of a patient The filter element comprises a collapsible filter body 2 and a filter support 3 for the filter body. The filter body has an inlet end 4 and an outlet end 5, the inlet end 4 of the filter body has one or more inlet openings 6 sized to allow blood and embolic material enter the filter body 2 and the outlet end 5 of the filter body has a plurality of outlet openings 107 sized to allow through passage of blood but to retain undesired embolic material within the filter body 2. The filter support 3 is movable between a collapsed position for movement through the vascular system, and an extended outwardly projecting position to support the filter body in an expanded position The filter support 3 comprises a generally tubular support frame defined by at least one wire 16.
摘要翻译：栓塞保护装置包括用于通过患者的血管系统输送的可折叠过滤器元件。过滤元件包括可折叠过滤器主体2和用于过滤器主体的过滤器支撑件3。过滤器本体具有入口端4和出口端5，过滤体的入口端4具有一个或多个入口开口6，其尺寸允许血液和栓塞物质进入过滤体2和过滤体的出口端5 具有多个出口开口107，其尺寸允许通过血液通过，但是将不期望的栓塞材料保持在过滤器主体2内。过滤器支撑件3可在通过血管系统移动的折叠位置和延伸向外突出的位置之间移动，以将过滤器主体支撑在扩张位置。过滤器支撑件3包括由至少一根线16限定的大体上管状的支撑框架。

10. 发明授权

US08114115B2 Support frame for an embolic protection device 有权
标题翻译：用于栓塞保护装置的支撑框架
公开(公告)号：US08114115B2
公开(公告)日：2012-02-14
申请号：US11762259
申请日：2007-06-13
申请人： Eamon Brady , David Vale , Ronald Kelly , John Neilan , Steven Horan , Gerard Rabitte , Gerry McCaffrey
发明人： Eamon Brady , David Vale , Ronald Kelly , John Neilan , Steven Horan , Gerard Rabitte , Gerry McCaffrey
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61B2017/2212 , A61B2017/2215 , A61F2002/016 , A61F2002/018 , A61F2230/0067 , A61F2230/0093
摘要： A support 103 for an embolic protection device comprises round wires 116 which may form one or more support hoops for a filter body. The circumferential hoop formed by the wires 116 ensures that in the expanded position, the filter body 102 will be supported by the support frame 103 in circumferential apposition with the interior wall of the vasculature. The wires 116 may have a strain distributing linkage element in the form of a loop 120. The loop 120 acts as a diameter or circumference adjuster allowing an embolic protection device to adapt to different Bessel contours and sizes whilst maintaining apposition with the vessel wall. The strain relieving geometry of the loops enhances the compliance of the bend points without creating a weakened hinge point, thus ensuring that there is no discontinuity in the circumferential seal against the vessel wall.
摘要翻译：用于栓塞保护装置的支撑件103包括圆形线116，其可以形成用于过滤器主体的一个或多个支撑环。由导线116形成的圆周箍确保在扩展位置中，过滤器主体102将由支撑框架103与脉管系统的内壁周向配合地支撑。线116可以具有环形120形式的应变分布联动元件。回路120用作直径或周长调节器，允许栓塞保护装置适应不同的贝塞尔轮廓和尺寸，同时保持与血管壁的配合。环的应变消除几何增加弯曲点的顺应性，而不产生削弱的铰链点，从而确保在围绕血管壁的周向密封中不存在中断。

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