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    • 3. 发明申请
    • Treatment of Pain
    • 疼痛治疗
    • US20080021075A1
    • 2008-01-24
    • US11780088
    • 2007-07-19
    • Ronald RosenburgJeffrey Miller
    • Ronald RosenburgJeffrey Miller
    • A61K31/426A61P25/04A61P25/06
    • A61K31/197A61K31/416A61K2300/00
    • The invention relates to a new medicamentation for the treatment of pain, in particular fibromyalgia. The medicamentation comprises the administration of pramipexole in combination with an analgesic of the class of chemical compounds structurally related with gamma aminobutyric acid (GABA) selected from the group of pregabaline and gabapentine. The medicamentation is either a combination of pramipexole and pregabaline or a combination of pramipexole and gabapentine, both of which may be used in a fixed dose combination as well as in a free dose combination. The invention further is related to the manufacture of a medicament for the treatment of pain, in particular fibromyalgia comprising said medicamentation and a method of treatment of pain, in particular fibromyalgia comprising said medicamentation.
    • 本发明涉及用于治疗疼痛,特别是纤维肌痛的新药物。 所述药物包括将普拉克索与与选自普瑞卡班和加巴喷丁组的γ-氨基丁酸(GABA)结构相关的化学化合物类别的镇痛药组合施用。 药物化学是普拉克索和普瑞卡班的组合或普拉克索与加巴喷丁的组合,两者均可以固定剂量组合以及游离剂量组合使用。 本发明还涉及用于治疗疼痛的药物的制备,特别是包括所述药物的纤维肌痛和治疗疼痛的方法,特别是包含所述药物化学的纤维肌痛。