专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5626852A Composition containing body activated fragrance for contacting the skin and method of use 失效
标题翻译：含有身体活性香料的组合物，用于接触皮肤和使用方法
公开(公告)号：US5626852A
公开(公告)日：1997-05-06
申请号：US364927
申请日：1994-12-23
申请人： Robert Suffis , Morton L. Barr , Kenya Ishida , Kiyohito Sawano , Augustinus G. van Loveren , Tetsuo Nakatsu , Carter B. Green , Gary A. Reitz , Raphael K. L. Kang , Toshiya Sato, deceased
发明人： Robert Suffis , Morton L. Barr , Kenya Ishida , Kiyohito Sawano , Augustinus G. van Loveren , Tetsuo Nakatsu , Carter B. Green , Gary A. Reitz , Raphael K. L. Kang , Toshiya Sato, deceased
IPC分类号： A61K31/74 , A61K20060101 , A61K8/37 , A61Q13/00 , A61Q15/00 , A61K7/00 , A61K7/46
CPC分类号： A61Q15/00 , A61K8/0229 , A61K8/37 , A61Q13/00 , A61K2800/262 , Y10S424/05
摘要： Described is a fragrancing composition having fragrancing components that are not activated until, e.g., application to the skin of a human. The composition is alkaline or (if anhydrous) capable of producing an alkaline pH when in contact with water, prior to application, and includes (1) a vehicle such that when the composition is in contact with water, prior to application, the composition is at an alkaline pH; and (2) at least one potential fragrance that is at least one compound having little or no odor in the alkaline composition but which, e.g., is hydrolyzed in a lower pH environment to produce compounds having a relatively strong aroma. Upon application of the alkaline composition to the skin surface, the strong buffering capacity of the skin (the surface of which has a normal pH of 5.5-7.0) neutralizes alkalinity of the composition (lowers pH) so as to restore normal skin surface pH; the potential fragrance is then hydrolyzed at the lower pH to release the compound having relatively strong aroma. The potential fragrance can be incorporated as a component of a transparent (clear) deodorant stick composition for application to human axillary regions, the fragrance being released after application to the body.
摘要翻译：描述了一种具有芳香组分的芳香组合物，其直到例如施用于人的皮肤为止才被活化。该组合物是碱性的或（如果是无水的）能够在施用之前与水接触时产生碱性pH，并且包括（1）一种车辆，使得当组合物与水接触时，在施用之前，组合物是在碱性pH下; 和（2）至少一种潜在的香料，其是至少一种在碱性组合物中具有很少或没有气味的化合物，例如在较低pH环境中水解以产生具有较强香味的化合物。当将碱性组合物施用于皮肤表面时，皮肤（其表面的正常pH为5.5-7.0）的强缓冲能力中和组合物的碱度（降低pH），以恢复正常的皮肤表面pH; 然后将潜在的香料在较低pH下水解以释放具有较强香味的化合物。潜在香料可以作为透明（透明）除臭棒组合物的组分掺入到人类腋窝区域中，该香料在施用于身体后被释放。

2. 发明授权

US5378468A Composition containing body activated fragrance for contacting the skin and method of use 失效
标题翻译：含有身体活性香料的组合物，用于接触皮肤和使用方法
公开(公告)号：US5378468A
公开(公告)日：1995-01-03
申请号：US948510
申请日：1992-09-22
申请人： Robert Suffis , Morton L. Barr , Kenya Ishida , Kiyohito Sawano , Toshiya Sato , Augustinus G. van Loveren
发明人： Robert Suffis , Morton L. Barr , Kenya Ishida , Kiyohito Sawano , Toshiya Sato , Augustinus G. van Loveren
IPC分类号： A61K31/74 , A61K20060101 , A61K8/37 , A61Q13/00 , A61Q15/00 , A61K7/00 , A61K7/32
CPC分类号： A61Q15/00 , A61K8/0229 , A61K8/37 , A61Q13/00 , A61K2800/262 , Y10S424/05
摘要： Described is a fragrancing composition having fragrancing components that are not activated until, e.g., application to the skin of a human. The composition is alkaline or (if anhydrous) capable of producing an alkaline pH when in contact with water, prior to application, and includes (1) a vehicle for application of the composition, and (2) at least one potential fragrance that is at least one compound having little or no odor in the alkaline composition but which, e.g., is hydrolyzed in a lower pH environment to produce compounds having a relatively strong aroma. Upon application of the alkaline composition to the skin surface, the strong buffering capacity of the skin (the surface of which has a normal pH of 5.5-7.0) neutralizes alkalinity of the composition (lowers pH) so as to restore normal skin surface pH; the potential fragrance is then hydrolyzed at the lower pH to release the compound having relatively strong aroma. The potential fragrance can be incorporated as a component of a transparent (clear) deodorant stick composition for application to human axillary regions, the fragrance being released after application to the body.
摘要翻译：描述了一种具有芳香组分的芳香组合物，其直到例如施用于人的皮肤为止才被活化。该组合物是碱性的或（如果是无水的）能够在施用之前与水接触时产生碱性pH，并且包括（1）施用该组合物的载体，和（2）至少一种潜在的香料，至少一种在碱性组合物中具有很少或没有气味的化合物，例如在较低pH环境中水解，生成具有较强香味的化合物。当将碱性组合物施用于皮肤表面时，皮肤的强缓冲能力（其表面的正常pH为5.5-7.0）中和组合物的碱度（降低pH），以恢复正常的皮肤表面pH; 然后将潜在的香料在较低pH下水解以释放具有较强香味的化合物。潜在香料可以作为透明（透明）除臭棒组合物的组分掺入到人类腋窝区域中，该香料在施用于身体后被释放。

3. 发明授权

US5380763A Topical composition for treating acne vulgaris 失效
标题翻译：用于治疗寻常痤疮的局部组合物
公开(公告)号：US5380763A
公开(公告)日：1995-01-10
申请号：US154458
申请日：1993-11-19
申请人： Toshiya Sato, deceased , Kenya Ishida
发明人： Toshiya Sato, deceased , Kenya Ishida
IPC分类号： A61K8/30 , A61K8/00 , A61K8/34 , A61K31/00 , A61K31/045 , A61P17/00 , A61P17/10 , A61P31/04 , A61Q19/00
CPC分类号： A61K8/342 , A61K31/045 , A61Q19/00 , Y10S514/844 , Y10S514/859
摘要： A topical composition for treating acne vulgaris comprising 1-pentadecanol as an active ingredient and a carrier or diluent acceptable for topical composition is disclosed. The composition is highly effective on Propionibacterium acnes and of high safety.
摘要翻译：公开了一种用于治疗寻常痤疮的局部组合物，其包含1-十五烷醇作为活性成分和局部组合物可接受的载体或稀释剂。该组合物对痤疮丙酸杆菌高度安全有效。

4. 发明授权

US06528074B2 Lipid composition containing a liquid crystal structure 有权
公开(公告)号：US06528074B2
公开(公告)日：2003-03-04
申请号：US09874312
申请日：2001-06-06
申请人： Izumi Kawada , Kenya Ishida , Kiyohito Sawano , Toshimitsu Hagiwara
发明人： Izumi Kawada , Kenya Ishida , Kiyohito Sawano , Toshimitsu Hagiwara
IPC分类号： A61K700
CPC分类号： A61Q19/00 , A61K8/0295 , A61K8/63 , A61K8/68 , A61K9/1274 , A61Q1/08 , A61Q17/00
摘要： This invention relates to a novel lipid composition for use in cosmetics capable of increasing moisture-keeping ability or barrier function of the stratum corneum, protecting the skin and improving dry or rough skin, and to products which use the same, such as cosmetics and medicaments. Particularly, it relates to a lipid composition which comprises at least one component (A) selected from the group consisting of a 2-acylaminoalkane-1,3-diol and optically active compounds thereof, at least one component (B) selected from the group consisting of a 2-acylaminoalkane-1,3-diol in which at least one of the &agr;-position and &bgr;-position of the acyl group is substituted with hydroxyl group and optically active compounds thereof and at least one component (C) selected from sterols, wherein the components (A), (B) and (C) are mixed at a ratio that constructs a liquid crystal structure, and to products which contain the lipid composition, such as cosmetics and medicaments.

5. 发明授权

US5141921A Perfume composition 失效
标题翻译：香水组成
公开(公告)号：US5141921A
公开(公告)日：1992-08-25
申请号：US683911
申请日：1991-04-11
申请人： Kiyohito Sawano , Kenya Ishida , Akemi Shimada
发明人： Kiyohito Sawano , Kenya Ishida , Akemi Shimada
IPC分类号： A61K8/36 , A61Q13/00 , C07C57/03 , C11B9/00
CPC分类号： A61Q13/00 , A61K8/361 , C07C57/03 , C11B9/0019 , A61K2800/70
摘要： A perfume composition containing 3-methyl-2-hexenoic acid and/or 7-octenoic acid is disclosed. The perfume composition has a fresh and natural animal note and excellent diffusibility and tastiness. The perfume composition produces psychological effects on humans, such as an awakening effect and/or a sedative effect.
摘要翻译：公开了含有3-甲基-2-己烯酸和/或7-辛烯酸的香料组合物。香水组合物具有清新自然的动物笔记，具有优异的扩散性和口感性。香水组合物对人类产生心理影响，例如觉醒作用和/或镇静作用。

6. 发明授权

US08741958B2 Synthetic spilanthol and use thereof 有权
标题翻译：合成稀释剂及其用途
公开(公告)号：US08741958B2
公开(公告)日：2014-06-03
申请号：US12505283
申请日：2009-07-17
申请人： Louis Lombardo , Michael E. Lankin , Kenya Ishida , Shigeru Tanaka , Hideo Ujihara , Kenji Yagi , Jennifer B. Mei , Carter B. Green , Amrit S. Mankoo
发明人： Louis Lombardo , Michael E. Lankin , Kenya Ishida , Shigeru Tanaka , Hideo Ujihara , Kenji Yagi , Jennifer B. Mei , Carter B. Green , Amrit S. Mankoo
IPC分类号： A23L1/221
CPC分类号： A61K8/42 , A23G1/32 , A23G3/36 , A23G4/06 , A23L27/202 , A61Q5/00 , A61Q11/00 , A61Q15/00 , C07C43/303 , C07C45/41 , C07C57/66 , C07C231/12 , C07C233/09 , C07C235/28 , C07C309/66 , C12P13/02 , C07C47/21
摘要： The present application provides a synthetic spilanthol flavor composition that includes (2E,6Z,8E)-N-(2-methylpropyl)-2,6,8-decatrienamide. The synthetic spilanthol composition can also contain, and at least one of (2E,6E,8E)-N-(2-methylpropyl)-2,6,8-decatrienamide and (2E,6Z,8Z)-N-(2-methylpropyl)-2,6,8-decatrienamide, the (N-(2-methylpropyl)-2,6,8-decatrienamide being present in amounts effective to impart a salivating or tingle effect while reducing the perception of off notes, as compared to the off-notes perceived upon consumption of natural spilanthol (e.g. spilanthol obtained from jambu oleoresin). Methods of increasing salivation and/or providing a tingling sensation upon consuming an orally consumable product that include adding to the product a synthetic spilanthol flavor composition are also provided. Synthetic spilanthol flavor compositions can be added to orally consumed products, such as, but not limited to, foods, beverages, pharmaceuticals, nutraceuticals, or therapeutic compositions, oral personal care products, gums (e.g. chewing gum or bubble gum), candy or lozenges.
摘要翻译：本申请提供了包括（2E，6Z，8E）-N-（2-甲基丙基）-2,6,8-十一三烯酰胺的合成稀释剂风味组合物。（2E，6E，8E）-N-（2-甲基丙基）-2,6,8-十一三烯酰胺和（2E，6Z，8Z）-N-（2- 甲基丙基）-2,6,8-十一三烯酰胺，（N-（2-甲基丙基）-2,6,8-癸三酰胺以有效赋予唾液或叮咬效果同时减少脱落感觉的量存在，相比之下在消费口服消耗品时，增加唾液分泌和/或提供刺痛感的方法包括向产品中加入合成的稀释剂风味组合物的方法也是合成的稀释剂风味组合物可以添加到口服食品中，例如但不限于食品，饮料，药物，营养保健品或治疗组合物，口腔个人护理产品，牙龈（例如口香糖或泡泡糖），糖果或锭剂。

7. 发明申请

US20100184863A1 SYNTHETIC SPILANTHOL AND USE THEREOF 有权
标题翻译：合成螺旋体及其用途
公开(公告)号：US20100184863A1
公开(公告)日：2010-07-22
申请号：US12505283
申请日：2009-07-17
申请人： Louis Lombardo , Michael E. Lankin , Kenya Ishida , Shigeru Tanaka , Hideo Ujihara , Kenji Yagi , Jennifer B. Mei , Carter B. Green , Amrit S. Mankoo
发明人： Louis Lombardo , Michael E. Lankin , Kenya Ishida , Shigeru Tanaka , Hideo Ujihara , Kenji Yagi , Jennifer B. Mei , Carter B. Green , Amrit S. Mankoo
IPC分类号： A61K31/16 , C07C233/09 , A61P43/00
CPC分类号： A61K8/42 , A23G1/32 , A23G3/36 , A23G4/06 , A23L27/202 , A61Q5/00 , A61Q11/00 , A61Q15/00 , C07C43/303 , C07C45/41 , C07C57/66 , C07C231/12 , C07C233/09 , C07C235/28 , C07C309/66 , C12P13/02 , C07C47/21
摘要： The present application provides a synthetic spilanthol flavor composition that includes (2E,6Z,8E)-N-(2-methylpropyl)-2,6,8-decatrienamide. The synthetic spilanthol composition can also contain, and at least one of (2E, 6E, 8E)-N-(2-methylpropyl)-2,6,8-decatrienamide and (2E, 6Z, 8Z)-N-(2-methylpropyl)-2,6,8-decatrienamide, the (N-(2-methylpropyl)-2,6,8-decatrienamide being present in amounts effective to impart a salivating or tingle effect while reducing the perception of off notes, as compared to the off-notes perceived upon consumption of natural spilanthol (e.g. spilanthol obtained from jambu oleoresin). Methods of increasing salivation and/or providing a tingling sensation upon consuming an orally consumable product that include adding to the product a synthetic spilanthol flavor composition are also provided. Synthetic spilanthol flavor compositions can be added to orally consumed products, such as, but not limited to, foods, beverages, pharmaceuticals, nutraceuticals, or therapeutic compositions, oral personal care products, gums (e.g. chewing gum or bubble gum), candy or lozenges.
摘要翻译：本申请提供了包括（2E，6Z，8E）-N-（2-甲基丙基）-2,6,8-十一三烯酰胺的合成稀释剂风味组合物。（2E，6E，8E）-N-（2-甲基丙基）-2,6,8-十一三烯酰胺和（2E，6Z，8Z）-N-（2- 甲基丙基）-2,6,8-十一三烯酰胺，（N-（2-甲基丙基）-2,6,8-癸三酰胺以有效赋予唾液或叮咬效果同时减少脱落感觉的量存在，相比之下在消费口服消耗品时，增加唾液分泌和/或提供刺痛感的方法包括向产品中加入合成的稀释剂风味组合物的方法也是合成的稀释剂风味组合物可以添加到口服食品中，例如但不限于食品，饮料，药物，营养保健品或治疗组合物，口腔个人护理产品，牙龈（例如口香糖或泡泡糖），糖果或锭剂。

8. 发明授权

US08586009B2 Process for producing (3S)-I-menthyl 3-hydroxybutyrate and sensate composition 有权
标题翻译：（3S）-1-羟基丁酸薄荷酯的制备方法和感官组成
公开(公告)号：US08586009B2
公开(公告)日：2013-11-19
申请号：US13601434
申请日：2012-08-31
申请人： Kazuma Hojo , Takashi Aida , Kenya Ishida
发明人： Kazuma Hojo , Takashi Aida , Kenya Ishida
IPC分类号： A23L1/226 , A61K8/37 , A61Q19/00
CPC分类号： A61K8/37 , A23G4/06 , A23L27/203 , A23L27/88 , A61K2800/244 , A61Q5/02 , A61Q11/00 , A61Q19/00 , C07B2200/07 , C07C67/31 , C07C2601/14 , C11B9/0034 , C07C69/675
摘要： Disclosed is a method for producing (3S)-l-menthyl 3-hydroxybutyrate of the following formula (I) by subjecting l-menthyl acetoacetate to asymmetric hydrogenation. The compound may be used as a cooling component or sensate component which does not have undesirable stimulus feeling, bitterness and the like and is excellent in the persistence of refresh-feeling and cool-feeling.
摘要翻译：公开了通过使1-薄荷酰乙酰乙酸酯进行不对称氢化制备下式（I）的（3S）-1-薄荷基-3-羟基丁酸酯的方法。该化合物可以用作不具有不期望的刺激感，苦味等的冷却组分或感觉组分，并且具有优异的刷新感和凉爽感。

9. 发明授权

US08377458B2 Cooling sensation agent composition, sensory stimulation agent composition and use of the same 失效
标题翻译：冷却感觉剂组合物，感觉刺激剂组合物及其用途
公开(公告)号：US08377458B2
公开(公告)日：2013-02-19
申请号：US12898939
申请日：2010-10-06
申请人： Yasuhiro Komatsuki , Tomoko Yamamoto , Takashi Aida , Kenya Ishida
发明人： Yasuhiro Komatsuki , Tomoko Yamamoto , Takashi Aida , Kenya Ishida
IPC分类号： A61Q5/02 , A61Q15/00 , A61Q13/10
CPC分类号： C07C69/34 , A61K8/37 , A61K31/225 , A61K2800/244 , A61Q11/00 , A61Q13/00 , A61Q15/00 , A61Q19/00 , C07C69/40 , C07C69/42 , C07C2601/14
摘要： Disclosed is a cooling sensation agent composition or sensory stimulation agent composition which contains at least one of diester compounds of dicarboxylic acid represented by the formula (1) wherein A represents CH2 or CH═CH, n represents an integer of 0 to 4 when A is CH2, or 1 when A is CH═CH, B is an alcohol residue having 10 to 18 carbon atoms and containing a para-menthane skeleton, which may have a substituent, and C is an alcohol residue having 6 to 18 carbon atoms, which may have a substituent as well as a flavor or fragrance composition, a beverage, a food product, a perfume or cosmetic product, a toiletry product, daily utensil products or groceries, a fiber, a fiber product, clothes, clothing or a medicine, wherein the cooling sensation agent composition or the sensory stimulation agent composition is compounded.
摘要翻译：公开了一种冷却感觉剂组合物或感觉刺激剂组合物，其含有由式（1）表示的二羧酸二酯化合物中的至少一种，其中A表示CH 2或CH = CH，n表示0至4的整数，当A为 CH 2或1，当A为CH = CH时，B为具有10至18个碳原子的醇残基，并含有可具有取代基的对位薄荷烷骨架，C为具有6至18个碳原子的醇残基，可以具有取代基以及香料或香料组合物，饮料，食品，香料或化妆品，化妆品，日用具产品或杂货，纤维，纤维制品，衣服，衣服或药物，其中所述冷却感觉剂组合物或所述感觉刺激剂组合物复合。

10. 发明申请

US20110118500A1 METHOD FOR PRODUCING OPTICALLY ACTIVE a-IONONE 有权
标题翻译：用于生产光学活性α-离子的方法
公开(公告)号：US20110118500A1
公开(公告)日：2011-05-19
申请号：US13012199
申请日：2011-01-24
申请人： Tetsuya Yamamoto , Kenji Yagi , Kenya Ishida
发明人： Tetsuya Yamamoto , Kenji Yagi , Kenya Ishida
IPC分类号： C07C69/78 , C07C69/533 , C07C69/63 , C07C69/24 , C07C69/708
CPC分类号： C12P7/26 , A23L2/56 , A23L27/204 , A61K8/37 , A61Q11/00 , A61Q13/00 , C07B53/00 , C07B2200/07 , C07C403/08 , C07C403/12 , C07C403/14 , C07C2601/16 , C12G3/06 , C12P41/004
摘要： Provided that a method for inexpensively producing optically active α-ionone with a high yield and a high asymmetric yield and with good workability in a short process, and a perfume composition comprising the optically active α-ionone obtained by the aforementioned method. A method for producing optically active α-ionone, comprising allowing α-ionone as a mixture of optical isomers to react with an esterification agent, and hydrolyzing the obtained α-ionone enol ester; a method for producing optically active α-ionone comprising subjecting α-ionone as a mixture of optical isomers to an asymmetric reduction, allowing the obtained optically active α-ionol to react with an esterification agent to give an optically active α-ionol ester, hydrolyzing the obtained optically active α-ionol ester after purification as necessary, and then oxidizing the obtained optically active α-ionol; and a perfume composition comprising thus obtained optically active α-ionone.
摘要翻译：本发明提供了一种低成本地生产光学活性α-紫罗兰酮的方法，其具有高产率和高不对称产率，并且在短时间内具有良好的可加工性，以及包含通过上述方法获得的光学活性α-紫罗兰酮的香料组合物。一种光学活性α-紫罗兰酮的制造方法，其特征在于，使作为旋光异构体的混合物的α-紫罗烯酮与酯化反应，水解得到的α-紫罗烯酮烯醇酯; 一种光学活性α-紫罗兰酮的制造方法，其特征在于，将α-紫罗烯酮作为光学异构体的混合物进行不对称还原，使得所得光学活性α-离子酚与酯化反应，得到光学活性α-离子醇酯，水解根据需要纯化后得到的光学活性α-离子醇酯，然后氧化所得光学活性α-离子醇; 和包含这样得到的光学活性α-紫罗兰酮的香料组合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式