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1. 发明申请

US20080051736A1 Sterilizable indwelling catheters 有权
标题翻译：可消毒的留置导管
公开(公告)号：US20080051736A1
公开(公告)日：2008-02-28
申请号：US11879537
申请日：2007-07-18
申请人： Robert Rioux , Raymond Lareau , Kristian Dimatteo
发明人： Robert Rioux , Raymond Lareau , Kristian Dimatteo
IPC分类号： A61M25/00
CPC分类号： A61L2/08 , A61L2/084 , A61L2/085 , A61L2/10 , A61L29/04 , A61L29/08 , A61L29/14 , A61M25/0017 , A61M2025/0056
摘要： According to an aspect of the invention, an indwelling catheter is provided which comprises a catheter shaft. The catheter either comprises a light source or is adapted to receive light from a light source, and is configured such that light is transmitted from the light source into the catheter shaft. Moreover, the catheter shaft is formed of a polymeric material that transmits a quantity of light from the light source that is effective to inactivate microorganisms on a surface of the catheter shaft upon activation of the light source. For example, the light may inactivate the microorganisms directly or in conjunction with a photosensitizer. According to another aspect of the invention, a sterilization method is provided, which comprises activating the light source while the catheter is inserted in a subject.
摘要翻译：根据本发明的一个方面，提供了一种留置导管，其包括导管轴。导管包括光源或适于接收来自光源的光，并且被配置为使得光从光源传输到导管轴。此外，导管轴由聚合物材料形成，该聚合物材料在光源激活时透射来自光源的一定量的光，其有效地使导管轴表面上的微生物灭活。例如，光可以直接或与光敏剂结合灭活微生物。根据本发明的另一方面，提供一种杀菌方法，其包括在将导管插入受试者时激活光源。

2. 发明授权

US08556950B2 Sterilizable indwelling catheters 有权
标题翻译：可消毒的留置导管
公开(公告)号：US08556950B2
公开(公告)日：2013-10-15
申请号：US11879537
申请日：2007-07-18
申请人： Robert Rioux , Raymond Lareau , Kristian Dimatteo
发明人： Robert Rioux , Raymond Lareau , Kristian Dimatteo
IPC分类号： A61N5/06
CPC分类号： A61L2/08 , A61L2/084 , A61L2/085 , A61L2/10 , A61L29/04 , A61L29/08 , A61L29/14 , A61M25/0017 , A61M2025/0056
摘要： According to an aspect of the invention, an indwelling catheter is provided which comprises a catheter shaft. The catheter either comprises a light source or is adapted to receive light from a light source, and is configured such that light is transmitted from the light source into the catheter shaft. Moreover, the catheter shaft is formed of a polymeric material that transmits a quantity of light from the light source that is effective to inactivate microorganisms on a surface of the catheter shaft upon activation of the light source. For example, the light may inactivate the microorganisms directly or in conjunction with a photosensitizer. According to another aspect of the invention, a sterilization method is provided, which comprises activating the light source while the catheter is inserted in a subject.
摘要翻译：根据本发明的一个方面，提供了一种留置导管，其包括导管轴。导管包括光源或适于接收来自光源的光，并且被配置为使得光从光源传输到导管轴。此外，导管轴由聚合物材料形成，该聚合材料在光源激活时透过来自光源的一定量的光，其有效地使导管轴表面上的微生物灭活。例如，光可以直接或与光敏剂结合灭活微生物。根据本发明的另一方面，提供一种杀菌方法，其包括在将导管插入受试者时激活光源。

3. 发明申请

US20060020256A1 Reinforced venous access catheter 有权
标题翻译：强化静脉导管
公开(公告)号：US20060020256A1
公开(公告)日：2006-01-26
申请号：US10894992
申请日：2004-07-20
申请人： Barbara Bell , George Bourne , Raymond Lareau , Kristian Dimatteo
发明人： Barbara Bell , George Bourne , Raymond Lareau , Kristian Dimatteo
IPC分类号： A61M25/00
CPC分类号： A61M25/0045 , A61M25/0052 , A61M25/0069 , A61M2025/0031 , A61M2025/0037 , A61M2025/0059 , A61M2025/0063
摘要： A catheter for medical procedures comprises a shaft portion having a distal end insertable into a body lumen, the shaft portion having a wall defining a working lumen extending therewithin and a first strengthening element coupled to the wall to increase a burst pressure of the shaft portion, wherein the first strengthening element cooperates with a base material of the wall to define a flexible region of the shaft portion allowing the shaft portion to be atraumatically inserted into the body lumen.
摘要翻译：用于医疗程序的导管包括轴部分，其具有可插入体腔的远端，所述轴部分具有限定在其中延伸的工作腔的壁和连接到所述壁的第一加强元件，以增加所述轴部的爆裂压力，其中所述第一加强元件与所述壁的基底材料配合以限定所述轴部分的柔性区域，从而允许所述轴部分被无损伤地插入到所述体腔内。

4. 发明申请

US20110054312A1 Reinforced Venous Access Catheter 审中-公开
标题翻译：强化静脉导管导管
公开(公告)号：US20110054312A1
公开(公告)日：2011-03-03
申请号：US12917964
申请日：2010-11-02
申请人： Barbara Bell , George Bourne , Raymond Lareau , Kristian Dimatteo
发明人： Barbara Bell , George Bourne , Raymond Lareau , Kristian Dimatteo
IPC分类号： A61M25/00 , A61B6/00
CPC分类号： A61M25/0045 , A61M25/0052 , A61M25/0069 , A61M2025/0031 , A61M2025/0037 , A61M2025/0059 , A61M2025/0063
摘要： A catheter for medical procedures comprises a shaft portion having a distal end insertable into a body lumen, the shaft portion having a wall defining a working lumen extending therewithin and a first strengthening element coupled to the wall to increase a burst pressure of the shaft portion, wherein the first strengthening element cooperates with a base material of the wall to define a flexible region of the shaft portion allowing the shaft portion to be atraumatically inserted into the body lumen.
摘要翻译：用于医疗程序的导管包括轴部分，其具有可插入体腔的远端，所述轴部分具有限定在其中延伸的工作腔的壁和连接到所述壁的第一加强元件，以增加所述轴部的爆裂压力，其中所述第一加强元件与所述壁的基底材料配合以限定所述轴部分的柔性区域，从而允许所述轴部分被无损伤地插入到所述体腔内。

5. 发明授权

US07850675B2 Reinforced venous access catheter 有权
标题翻译：强化静脉导管
公开(公告)号：US07850675B2
公开(公告)日：2010-12-14
申请号：US10894992
申请日：2004-07-20
申请人： Barbara Bell , George Bourne , Raymond Lareau , Kristian DiMatteo
发明人： Barbara Bell , George Bourne , Raymond Lareau , Kristian DiMatteo
IPC分类号： A61M25/00
CPC分类号： A61M25/0045 , A61M25/0052 , A61M25/0069 , A61M2025/0031 , A61M2025/0037 , A61M2025/0059 , A61M2025/0063
摘要： A catheter for medical procedures comprises a shaft portion having a distal end insertable into a body lumen, the shaft portion having a wall defining a working lumen extending therewithin and a first strengthening element coupled to the wall to increase a burst pressure of the shaft portion, wherein the first strengthening element cooperates with a base material of the wall to define a flexible region of the shaft portion allowing the shaft portion to be atraumatically inserted into the body lumen.
摘要翻译：用于医疗程序的导管包括轴部分，其具有可插入体腔的远端，所述轴部分具有限定在其中延伸的工作腔的壁和连接到所述壁的第一加强元件，以增加所述轴部的爆裂压力，其中所述第一加强元件与所述壁的基底材料配合以限定所述轴部分的柔性区域，从而允许所述轴部分被无损伤地插入到所述体腔内。

6. 发明申请

US20080051702A1 Therapeutic agent delivery for the treatment of asthma via implantable and insertable medical devices 审中-公开
标题翻译：通过可植入和可插入的医疗设备治疗哮喘的治疗剂递送
公开(公告)号：US20080051702A1
公开(公告)日：2008-02-28
申请号：US11726608
申请日：2007-03-22
申请人： Robert A. Herrmann , John J. Damarati , Sepideh Hashemi , Wendy Naimark , Barry N. Gellman , Robert Rioux , Alexandra Rousseau , Raymond Lareau
发明人： Robert A. Herrmann , John J. Damarati , Sepideh Hashemi , Wendy Naimark , Barry N. Gellman , Robert Rioux , Alexandra Rousseau , Raymond Lareau
IPC分类号： A61K31/573
CPC分类号： A61K31/573
摘要： Methods for the treatment of asthma are provided, which comprise: (a) providing an implantable or insertable medical device that comprises an asthma treatment agent; and (b) inserting or implanting the medical device within the lungs (e.g., the trachea or the bronchial tree) of a patient, whereupon the therapeutic agent is delivered to the patient in an amount effective to reduce or eliminate the symptoms of asthma. Also disclosed herein are medical devices and kits for carrying out such methods.
摘要翻译：提供了治疗哮喘的方法，其包括：（a）提供包含哮喘治疗剂的可植入或可插入的医疗装置; 和（b）将医疗装置插入或植入患者的肺部（例如，气管或支气管树）中，于是将治疗剂以有效减少或消除哮喘症状的量递送给患者。本文还公开了用于执行这些方法的医疗装置和套件。

7. 发明申请

US20120231047A1 THERAPEUTIC AGENT DELIVERY FOR THE TREATMENT OF ASTHMA VIA IMPLANTABLE AND INSERTABLE MEDICAL DEVICES 审中-公开
标题翻译：通过可植入和插入式医疗器械治疗哮喘的治疗药物
公开(公告)号：US20120231047A1
公开(公告)日：2012-09-13
申请号：US13480227
申请日：2012-05-24
申请人： Robert A. Herrmann , John J. Damarati , Sepideh Hashemi , Wendy Naimark , Barry N. Gellman , Robert Rioux , Alexandra Rousseau , Raymond Lareau
发明人： Robert A. Herrmann , John J. Damarati , Sepideh Hashemi , Wendy Naimark , Barry N. Gellman , Robert Rioux , Alexandra Rousseau , Raymond Lareau
IPC分类号： A61K31/56 , A61K47/02 , A61P11/06 , A61M37/00 , A61P35/00 , A61P21/02 , A61M25/10 , A61K9/00 , A61P29/00
CPC分类号： A61K31/573
摘要： Methods for the treatment of asthma are provided, which comprise: (a) providing an implantable or insertable medical device that comprises an asthma treatment agent; and (b) inserting or implanting the medical device within the lungs (e.g., the trachea or the bronchial tree) of a patient, whereupon the therapeutic agent is delivered to the patient in an amount effective to reduce or eliminate the symptoms of asthma. Also disclosed herein are medical devices and kits for carrying out such methods.
摘要翻译：提供了治疗哮喘的方法，其包括：（a）提供包含哮喘治疗剂的可植入或可插入的医疗装置; 和（b）将医疗装置插入或植入患者的肺部（例如，气管或支气管树）中，于是将治疗剂以有效减少或消除哮喘症状的量递送给患者。本文还公开了用于执行这些方法的医疗装置和套件。

8. 发明授权

US09707339B2 High flow rate dual reservoir port system 有权
公开(公告)号：US09707339B2
公开(公告)日：2017-07-18
申请号：US13852436
申请日：2013-03-28
申请人： Bradley D. Chartrand , Raymond Lareau , Daniel Buehner , Tobin Kovoor , Brian F. Nentwick
发明人： Bradley D. Chartrand , Raymond Lareau , Daniel Buehner , Tobin Kovoor , Brian F. Nentwick
IPC分类号： A61M5/142 , A61M1/00 , A61M5/158 , A61M1/36 , A61M39/02
CPC分类号： A61M5/14276 , A61M1/3659 , A61M1/3661 , A61M2039/0211 , A61M2205/04
摘要： Devices and methods for obtaining high flow rates in a port catheter system, and devices and methods for using a high flow rate port catheter system are disclosed. In one embodiment, a reservoir is dedicated for aspiration and a separate reservoir is dedicated for infusion. Fluid flow channels associated with aspiration are larger than the fluid flow channels associated with infusion. The catheter connected to the port can have an offset tip configuration. Methods for accessing the port are also disclosed.

9. 发明申请

US20130220462A1 Pressure Activated Valve for High Flow Rate and Pressure Venous Access Applications 有权
标题翻译：用于高流量和压力静电接触应用的压力活化阀
公开(公告)号：US20130220462A1
公开(公告)日：2013-08-29
申请号：US13566386
申请日：2012-08-03
申请人： Raymond Lareau , Mark Girard , Benjamin Bell
发明人： Raymond Lareau , Mark Girard , Benjamin Bell
IPC分类号： F16K15/14
CPC分类号： A61M39/24 , A61M2039/2426 , A61M2039/246 , F16K15/147 , F16K27/0209 , Y10T137/7881
摘要： A valve having a first housing including a first lumen extending therethrough and a first disk-facing surface, a second housing including a second lumen extending therethrough and a second disk-facing surface, where the second housing is coupled to the first housing so that the second disk-facing surface faces the first disk-facing surface. A flexible disk has at least a portion of an outer edge of the disk extending away from a plane of a central portion of the disk, the outer edge contacting the first disk-facing surface, the disk including a slit extending therethrough which, when acted upon by a fluid pressure of at least a threshold level opens to permit fluid flow between the first and second lumens and which, when acted upon by a fluid pressure less than the threshold level, prevents fluid flow between the first and second lumens.
摘要翻译：一种具有第一壳体的阀，所述第一壳体包括延伸穿过其中的第一内腔和第一盘对面的表面，第二壳体包括延伸穿过其中的第二腔和第二盘对面的表面，其中所述第二壳体联接到所述第一壳体，第二面向盘的表面面向第一面向盘的表面。柔性盘具有盘的外边缘的至少一部分远离盘的中心部分的平面延伸，外边缘接触第一面向盘的表面，盘包括延伸穿过其中的狭缝，当作用时通过至少阈值水平的流体压力打开以允许流体在第一和第二流明之间流动，并且当由低于阈值水平的流体压力作用时，防止流体在第一和第二流明之间流动。

10. 发明申请

US20160228616A1 DIALYSIS CATHETERS WITH FLUOROPOLYMER ADDITIVES 有权
标题翻译：透析导管与荧光增白剂
公开(公告)号：US20160228616A1
公开(公告)日：2016-08-11
申请号：US15132116
申请日：2016-04-18
申请人： Raymond Lareau , Benjamin Bell , Jeannette Ho , J. Paul Santerre , Carol Lancette , Theodore Beyer , William Appling
发明人： Raymond Lareau , Benjamin Bell , Jeannette Ho , J. Paul Santerre , Carol Lancette , Theodore Beyer , William Appling
IPC分类号： A61L29/06 , A61M25/00 , A61M1/36 , A61L29/18
CPC分类号： A61L29/06 , A61L29/041 , A61L29/14 , A61L29/18 , A61M1/3653 , A61M1/3659 , A61M25/0071 , A61M2025/0031 , A61M2025/0073 , C08L27/12 , C08L75/04
摘要： A vascular access catheter is disclosed that has a catheter shaft with a distal end portion with a distal tip having a sloped face that is positioned at an acute angle from the distal tip relative to a longitudinal axis of the catheter shaft. A first, second, and third lumen extend longitudinally through the catheter shaft. The third lumen is configured for receiving a guidewire and may extend a partial length of the catheter or substantially the entire length of the catheter. The first lumen has an aperture located in the angled edge distal end portion of the catheter next to the distal tip and communicates with the first lumen. The second lumen has an aperture that is positioned in the outer surface of the catheter shaft that is in communication with the second lumen, and is spaced proximally from the first lumen aperture. The catheter includes a fluoropolymer additive with specific compositions and/or purity levels.
摘要翻译：公开了一种血管通路导管，其具有导管轴，该导管轴具有远端部分，远侧末端具有倾斜面，该倾斜面相对于导管轴的纵向轴线与远侧末端成锐角。第一，第二和第三腔纵向延伸穿过导管轴。第三腔构造成用于接收导丝，并且可延伸导管的部分长度或导管的整个长度。第一管腔具有位于导管的邻近远侧末端的成角度的边缘远端部分中的孔，并且与第一管腔连通。第二管腔具有定位在导管轴的与第二内腔连通的外表面中并且与第一管腔开口向近侧间隔开的孔。导管包括具有特定组成和/或纯度水平的氟聚合物添加剂。

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