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    • 1. 发明申请
    • Spectral polarizing tomographic dermatoscope
    • 光谱偏振层析成像皮肤镜
    • US20080132794A1
    • 2008-06-05
    • US12011580
    • 2008-01-28
    • Robert R. AlfanoYury BudanskyJingcheng LuoManuel E. Zevallos
    • Robert R. AlfanoYury BudanskyJingcheng LuoManuel E. Zevallos
    • A61B6/00
    • A61B5/0059A61B5/0013A61B5/0068A61B5/0073A61B5/0084A61B5/415A61B5/418A61B5/4331A61B5/443A61B5/444A61B5/445
    • An apparatus for use in examining an object, such as skin, mucosa and cervical tissues for detecting cancer and precancerous conditions therein. In one embodiment, the apparatus includes a gun-shaped housing having a handle portion and a barrel portion. The front end of the barrel portion is open, and a glass cover is mounted therein. LED's are disposed within the handle portion. A manually-operable switch for controlling actuation of the LED's is accessible on the handle portion. An optical fiber is used to transmit light from the LED's through a first polarizer in the barrel portion and then through the glass cover to illuminate a desired object. Reflected light from the object is passed through a second polarizer, which is adjustably mounted in the barrel portion and which is preferably oriented to pass depolarized light emitted from an illuminated object, and is then imaged by optics onto a CCD detector. The detector is coupled to a wireless transmitter that transmits the output from the detector to a remotely located wireless receiver.
    • 用于检查诸如皮肤,粘膜和子宫颈组织的物体以检测其中的癌症和癌前病症的装置。 在一个实施例中,该装置包括具有手柄部分和镜筒部分的枪形壳体。 筒部的前端开放,玻璃罩安装在其中。 LED设置在手柄部分内。 用于控制LED的致动的手动操作开关可在手柄部分上进行。 光纤用于通过筒部中的第一偏振器从LED透射光,然后通过玻璃盖照射所需物体。 来自物体的反射光穿过第二偏振器,第二偏振器可调节地安装在镜筒部分中,并且其优选地定向成使从被照射物体发射的去偏振光通过,然后通过光学器件被成像到CCD检测器上。 该检测器耦合到将检测器的输出传输到远程位置的无线接收器的无线发射器。
    • 2. 发明授权
    • Spectral polarizing tomographic dermatoscope
    • 光谱偏振层析成像皮肤镜
    • US06587711B1
    • 2003-07-01
    • US09550094
    • 2000-04-14
    • Robert R. AlfanoYury BudanskyJingcheng Luo
    • Robert R. AlfanoYury BudanskyJingcheng Luo
    • A61B600
    • A61B5/444A61B5/0002A61B5/0068A61B5/0073A61B5/0084A61B5/415A61B5/418A61B5/4331
    • An apparatus for use in examining an object, such as skin, mucosa and cervical tissues for the purpose of detecting cancer and precancerous conditions therein. In one embodiment, the apparatus includes a gun-shaped housing having a handle portion and a barrel portion. The front end of the barrel portion is open, and a glass cover is mounted therein. Red, green, blue, and white LED's are disposed within the handle portion of the housing and are electrically connected to a battery also disposed within the handle portion of the housing. A manually-operable switch for controlling actuation of each of the four LED's is accessible on the handle portion of the housing. An optical fiber is disposed inside the housing and is used to transmit light from the four LED's through a first polarizer disposed in the barrel portion of the housing and then through the glass cover to illuminate a desired object. Reflected light from the object entering the housing through the glass cover is passed through a second polarizer, which is adjustably mounted in the barrel portion of the housing and which is preferably oriented to pass depolarized light emitted from an illuminated object, and is then imaged by optics onto a CCD detector. The optics may include a lens that is disposed within the barrel portion and is adjustably spaced relative to the CCD detector. The detector is coupled to a wireless transmitter mounted in the housing, the transmitter transmitting the output from the detector to a remotely located wireless receiver. The wireless receiver is coupled to a computer, which then processes the output from the detector. The processed output is then displayed on a display. The display may be remotely situated for remote expert diagnosis.
    • 用于检查诸如皮肤,粘膜和宫颈组织的物体的装置,用于检测其中的癌症和癌前病症。 在一个实施例中,该装置包括具有手柄部分和镜筒部分的枪形壳体。 筒部的前端开放,玻璃罩安装在其中。 红色,绿色,蓝色和白色LED设置在壳体的手柄部分内并且电连接到也设置在壳体的手柄部分内的电池。 用于控制四个LED中的每一个的致动的手动操作开关可在壳体的手柄部分上进行。 光纤设置在壳体内部,并用于透过设置在壳体的筒体部分中的第一偏振片透过来自四个LED的光,然后通过玻璃罩照射所需的物体。 来自通过玻璃盖进入壳体的物体的反射光穿过第二偏振器,第二偏振器可调节地安装在壳体的镜筒部分中,并且其优选地定向成使从被照射物体发射的去偏振光通过,然后通过 光学到CCD检测器。 光学器件可以包括设置在镜筒部分内并且相对于CCD检测器可调节间隔的透镜。 检测器耦合到安装在壳体中的无线发射器,发射器将检测器的输出传输到远程定位的无线接收器。 无线接收器耦合到计算机,然后计算机处理来自检测器的输出。 然后将处理的输出显示在显示屏上。 显示器可以远程位置用于远程专家诊断。