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1. 发明授权

US06267783B1 Stent which is easily recaptured and repositioned within the body 有权
公开(公告)号：US06267783B1
公开(公告)日：2001-07-31
申请号：US09626558
申请日：2000-07-27
申请人： Robert P. Letendre , Kenneth S. Solovay
发明人： Robert P. Letendre , Kenneth S. Solovay
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61F2/89 , A61F2/90 , A61F2/91 , A61F2/95 , A61F2002/075 , A61F2002/8486 , A61F2002/9505 , A61F2002/9534 , A61F2002/9665
摘要： In accordance with the present invention there is provided a pre-cursor stent for positioning within the infrarenal neck, between an abdominal aortic aneurysm and the renal arteries of a patient to assist in repairing the abdominal aortic aneurysm. The stent is designed to be coupled to a graft for directing blood flow through the aneurysm. The stent is made from a substantially cylindrical self-expanding member having a proximal end, a distal end, a longitudinal axis extending therebetween and an interior. The precursor stent further includes at least two spaced apart longitudinal legs having distal and proximal ends, the proximal ends of the legs attached to the distal end of the member, the legs extending distally from the member, each the leg including a flange adjacent its distal end. Also in accordance with the present invention is an aortic graft, having the above mentioned precursor stent attached thereto when fully deployed. Further in accordance with the present invention is a delivery apparatus for the above described precursor stent.

2. 发明授权

US06942692B2 Supra-renal prosthesis and renal artery bypass 有权
标题翻译：超肾假体和肾动脉旁路
公开(公告)号：US06942692B2
公开(公告)日：2005-09-13
申请号：US10041401
申请日：2002-01-08
申请人： George D. Landau , Robert P. Letendre , Kenneth S. Solovay
发明人： George D. Landau , Robert P. Letendre , Kenneth S. Solovay
IPC分类号： A61F2/06 , A61F2/07 , A61F2/82 , A61F2/848 , A61F2/856 , A61F2/86 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2/954
CPC分类号： A61F2/86 , A61B17/064 , A61B17/0682 , A61F2/064 , A61F2/07 , A61F2/848 , A61F2/856 , A61F2/88 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2/954 , A61F2002/061 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/825 , A61F2002/9505 , A61F2220/0041 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2230/001 , A61F2230/0013 , A61F2230/005 , A61F2230/0067 , A61F2230/0078 , A61F2250/006 , A61F2250/0069 , A61F2250/0071
摘要： The present invention is a system, apparatus, and method for treating, repairing, and/or replacing an aneurysm, preferably an aortic aneurysm, the most preferably, an abdominal aortic aneurysm. The systems, devices, and methods of the present invention include a first prosthesis or stent gasket, and at least one second prosthesis for bypassing the aneurysm, and at least one third prosthesis for establishing a fluid flow channel from the abdominal aorta into another artery, such as a renal artery.
摘要翻译：本发明是用于治疗，修复和/或替代动脉瘤，优选主动脉瘤，最优选为腹主动脉瘤的系统，装置和方法。本发明的系统，装置和方法包括第一假体或支架垫片以及用于绕过动脉瘤的至少一个第二假体，以及用于建立从腹主动脉到另一个动脉的流体流动通道的至少一个第三假体，如肾动脉。

3. 发明授权

US06290731B1 Aortic graft having a precursor gasket for repairing an abdominal aortic aneurysm 失效
标题翻译：主动脉移植物具有用于修复腹主动脉瘤的前体垫片
公开(公告)号：US06290731B1
公开(公告)日：2001-09-18
申请号：US09050347
申请日：1998-03-30
申请人： Kenneth S. Solovay , Robert P. Letendre
发明人： Kenneth S. Solovay , Robert P. Letendre
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/065 , A61F2002/075 , A61F2230/0054
摘要： In accordance with the present invention there is provided a pre-cursor stent for positioning within the infrarenal neck, between an abdominal aortic aneurysm and the renal arteries, of a patient to assist in repairing the abdominal aortic aneurysm. The stent designed to be coupled to a graft for directing blood flow. The graft has a distal end for positioning distal to the aneurysm, and a proximal end for positioning proximal to the aneurysm. The precursor stent includes a substantially cylindrical expandable member having a proximal end, a distal end and an interior. The stent further includes a compressible gasket member located within the interior of the expandable member and attached thereto. The compressible member is substantially impervious to water when in a compressed state. In addition, the stent has a means, within the compressible member, for coupling the graft to the gasket member. This is so the coupled device can direct blood flow therethrough, with the gasket member substantially preventing blood from flowing into the aneurysm.
摘要翻译：根据本发明，提供了一种用于定位在患者的腹主动脉瘤和肾动脉之间的肾下颈部内的辅助修复腹主动脉瘤的前置支架。该支架设计成与移植物联接以引导血流。移植物具有用于远端定位于动脉瘤的远端，以及用于定位在动脉瘤附近的近端。前体支架包括具有近端，远端和内部的基本上圆柱形的可扩张构件。支架还包括位于可扩张构件的内部并附接到其上的可压缩衬垫构件。当处于压缩状态时，可压缩构件基本上不透水。此外，支架具有在可压缩构件内的用于将移植物联接到垫圈构件的装置。因此，耦合的装置可以引导血液流过其中，垫圈构件基本上防止血液流入动脉瘤。

4. 发明授权

US06214036B1 Stent which is easily recaptured and repositioned within the body 有权
标题翻译：支架容易重新取代并重新定位在体内
公开(公告)号：US06214036B1
公开(公告)日：2001-04-10
申请号：US09188582
申请日：1998-11-09
申请人： Robert P. Letendre , Kenneth S. Solovay
发明人： Robert P. Letendre , Kenneth S. Solovay
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61F2/89 , A61F2/90 , A61F2/91 , A61F2/95 , A61F2002/075 , A61F2002/8486 , A61F2002/9505 , A61F2002/9534 , A61F2002/9665
摘要： In accordance with the present invention there is provided a pre-cursor stent for positioning within the infrarenal neck, between an abdominal aortic aneurysm and the renal arteries of a patient to assist in repairing the abdominal aortic aneurysm. The stent is designed to be coupled to a graft for directing blood flow through the aneurysm. The stent is made from a substantially cylindrical self-expanding member having a proximal end, a distal end, a longitudinal axis extending therebetween and an interior. The precursor stent further includes at least two spaced apart longitudinal legs having distal and proximal ends, the proximal ends of the legs attached to the distal end of the member, the legs extending distally from the member, each the leg including a flange adjacent its distal end. Also in accordance with the present invention is an aortic graft, having the above mentioned precursor stent attached thereto when fully deployed. Further in accordance with the present invention is a delivery apparatus for the above described precursor stent.
摘要翻译：根据本发明，提供了一种用于定位在肾下颈部，腹主动脉瘤和患者的肾动脉之间的前置支架，以辅助修复腹主动脉瘤。支架被设计成与移植物联接以引导血液流过动脉瘤。支架由具有近端，远端，在其间延伸的纵向轴线和内部的基本上圆柱形的自膨胀构件制成。前体支架还包括具有远端和近端的至少两个间隔开的纵向腿，腿的近端附接到构件的远端，腿从构件向远侧延伸，每个腿包括邻近其远端的凸缘结束。根据本发明，也是主动脉移植物，当完全展开时，其具有附着于其上的前述前体支架。此外，根据本发明，用于上述前体支架的输送装置。

5. 发明授权

US07267685B2 Bilateral extension prosthesis and method of delivery 有权
标题翻译：双侧延伸假体和分娩方法
公开(公告)号：US07267685B2
公开(公告)日：2007-09-11
申请号：US10041373
申请日：2002-01-08
申请人： Frank Butaric , William L. Howat , Robert P. Letendre , Marc Ramer , Kenneth S. Solovay
发明人： Frank Butaric , William L. Howat , Robert P. Letendre , Marc Ramer , Kenneth S. Solovay
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61B17/064 , A61B17/0682 , A61F2/064 , A61F2/848 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/077 , A61F2002/825 , A61F2230/0013 , A61F2230/0034 , A61F2250/006
摘要： The invention is a system, apparatus, and method for treating, and/or repairing an aneurysm, preferably an aortic aneurysm, and most preferably, an abdominal aortic aneurysm. The systems, devices, and methods of the present invention include a prosthesis assembly for establishing a fluid flow path between an upstream portion of an artery and at least one bifurcated downstream portion of the artery.
摘要翻译：本发明是用于治疗和/或修复动脉瘤，优选主动脉瘤，并且最优选腹主动脉瘤的系统，装置和方法。本发明的系统，装置和方法包括用于在动脉的上游部分和动脉的至少一个分叉的下游部分之间建立流体流动路径的假体组件。

6. 发明授权

US07229472B2 Thoracic aneurysm repair prosthesis and system 有权
标题翻译：胸腔动脉瘤修复假体和系统
公开(公告)号：US07229472B2
公开(公告)日：2007-06-12
申请号：US10041174
申请日：2002-01-08
申请人： Donald F. DePalma , Clifford J. Dwyer , Robert P. Letendre , Kenneth S. Solovay
发明人： Donald F. DePalma , Clifford J. Dwyer , Robert P. Letendre , Kenneth S. Solovay
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61B17/064 , A61B17/0682 , A61F2/064 , A61F2/848 , A61F2/88 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/061 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/825 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2220/0075 , A61F2230/001 , A61F2230/0013 , A61F2230/005 , A61F2250/006
摘要： The invention is a system, apparatus, and method for treating or repairing, an aneurysm in a large vessel, such as a thoracic aneurysm. The systems, devices, and methods of the present invention include a first prosthesis for anchoring a proximal end of the system in the blood vessel, a second prosthesis for anchoring a distal end of the system, and at least one third second prosthesis for bypassing the aneurysm, the first prosthesis optionally further comprising a seat or the like adapted and configured to receive the third prosthesis.
摘要翻译：本发明是用于治疗或修复诸如胸动脉瘤的大血管中的动脉瘤的系统，装置和方法。本发明的系统，装置和方法包括用于将系统的近端锚定在血管中的第一假体，用于锚定系统的远端的第二假体和用于绕过该系统的至少一个第三假肢动脉瘤，第一假体可选地进一步包括适于并构造成接收第三假体的座位或类似物。

7. 发明授权

US06270525B1 Precursor stent gasket for receiving bilateral grafts having controlled contralateral guidewire access 有权
标题翻译：用于接受具有受控对侧导丝通路的双侧移植物的前体支架垫片
公开(公告)号：US06270525B1
公开(公告)日：2001-08-07
申请号：US09404660
申请日：1999-09-23
申请人： Robert P. Letendre , Kenneth S. Solovay , Ivan A. Toyos
发明人： Robert P. Letendre , Kenneth S. Solovay , Ivan A. Toyos
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2230/0034 , A61F2230/0054
摘要： A precursor stent for implantation within the body of a patient is utilized in combination with an aortic graft for repairing an abdominal aortic aneurysm. The stent is designed to receive a pair of grafts placed side by side within the interior of the stent. The stent includes a substantially cylindrical and expandable member having a proximal end, a distal end, a longitudinal axis extending therebetween and an interior. The stent further includes an occlusive member attached to the expandable member. The occlusive member at least partially occludes a passageway or stent lumen which extends through the interior of the expandable member extending between its distal end and proximal end. The occlusive member has an opening extending therethrough designed to receive a guidewire for one of the grafts. Therefore, when the guidewire for the other graft is introduced, after deployment of the stent within a body, it will go through the portion of the interior not covered by the occlusive member. This helps to ensure proper side by side placement of the two grafts.
摘要翻译：将用于植入患者体内的前体支架与用于修复腹主动脉瘤的主动脉移植物组合使用。支架被设计成接收在支架内部并排放置的一对移植物。支架包括基本上圆柱形和可扩张的构件，其具有近端，远端，在其间延伸的纵向轴线和内部。支架还包括附接到可扩张构件的闭塞构件。所述闭塞构件至少部分地封闭通过所述可伸展构件的内部延伸的通道或支架内腔，所述可扩张构件的内部在其远端和近端之间延伸。闭塞构件具有延伸穿过的开口，其设计成接收用于移植物之一的导丝。因此，当引导其他移植物的导丝时，在将支架部署在体内之后，其将穿过未被闭塞构件覆盖的内部的一部分。这有助于确保两个移植物的适当并排放置。

8. 发明授权

US08632513B2 Systems and methods for removing ingested material from a stomach 有权
公开(公告)号：US08632513B2
公开(公告)日：2014-01-21
申请号：US13078838
申请日：2011-04-01
申请人： Dean Kamen , Kevin L. Grant , Eric M. Soederberg , David E. Altobelli , David Flynn , Kenneth S. Solovay , Samuel Klein
发明人： Dean Kamen , Kevin L. Grant , Eric M. Soederberg , David E. Altobelli , David Flynn , Kenneth S. Solovay , Samuel Klein
IPC分类号： A61M1/00 , A61M39/00 , A61M39/22 , A61F5/44
CPC分类号： A61F5/44
摘要： When a patient is fitted with an external gastrostomy connection to the stomach, ingested food can be removed through the gastrostomy connection using a pump-based or siphon-based system to achieve weight loss. The process of removing ingested food can be improved by alternating the infusion of liquid into the stomach with the removal of material from the stomach. Optionally, stomach acid may be captured and returned to the stomach. Optionally, nutritional supplements or medicines may be added to the infused liquid. Optionally, a flush mount connectorized system with a built in valve may be used to simplify the interface with the gastrostomy hardware that remains installed in the patient. Optionally, the system may be configured to disable itself from further use after a triggering event (e.g., the passage of time or a predetermined number of uses) has occurred.

9. 发明授权

US08062285B2 Systems and methods for removing ingested material from a stomach 有权
公开(公告)号：US08062285B2
公开(公告)日：2011-11-22
申请号：US11675544
申请日：2007-02-15
申请人： Tim Langloss , Dean Kamen , Kevin L. Grant , Eric M. Soederberg , David E. Altobelli , David M. Flynn , Kenneth S. Solovay , Samuel Klein
发明人： Tim Langloss , Dean Kamen , Kevin L. Grant , Eric M. Soederberg , David E. Altobelli , David M. Flynn , Kenneth S. Solovay , Samuel Klein
IPC分类号： A61M1/00 , A61M5/00 , A61F5/44
CPC分类号： A61F5/0076 , A61F5/0089 , A61J15/0015 , A61M1/0023 , A61M1/0062 , A61M3/0229 , A61M5/142 , A61M39/0247 , A61M39/1011 , A61M39/223 , A61M39/26 , A61M2039/0255 , A61M2205/276 , A61M2205/52 , A61M2210/1053
摘要： When a patient is fitted with an external gastrostomy connection to the stomach, ingested food can be removed through the gastrostomy connection using a pump-based or siphon-based system to achieve weight loss. The process of removing ingested food can be improved by alternating the infusion of liquid into the stomach with the removal of material from the stomach. Optionally, stomach acid may be captured and returned to the stomach. Optionally, nutritional supplements or medicines may be added to the infused liquid. Optionally, a flush mount connectorized system with a built in valve may be used to simplify the interface with the gastrostomy hardware that remains installed in the patient. Optionally, the system may be configured to disable itself from further use after a triggering event (e.g., the passage of time or a predetermined number of uses) has occurred.

10. 发明授权

US08002758B2 Systems and methods for removing ingested material from a stomach 有权
标题翻译：从胃中去除摄取的物质的系统和方法
公开(公告)号：US08002758B2
公开(公告)日：2011-08-23
申请号：US11890274
申请日：2007-08-03
申请人： Dean Kamen , Kevin L. Grant , Eric M. Soederberg , David E. Altobelli , David Flynn , Kenneth S. Solovay , Samuel Klein
发明人： Dean Kamen , Kevin L. Grant , Eric M. Soederberg , David E. Altobelli , David Flynn , Kenneth S. Solovay , Samuel Klein
IPC分类号： A61M1/00 , A61F5/44 , F16K25/00 , F16L37/28
CPC分类号： A61F5/0076 , A61F5/0089 , A61J15/0015 , A61M1/0023 , A61M1/0062 , A61M3/0229 , A61M5/142 , A61M39/0247 , A61M39/1011 , A61M39/223 , A61M39/26 , A61M2039/0255 , A61M2205/276 , A61M2205/52 , A61M2210/1053
摘要： When a patient is fitted with an external gastrostomy connection to the stomach, ingested food can be removed through the gastrostomy connection using a pump-based or siphon-based system to achieve weight loss. The process of removing ingested food can be improved by alternating the infusion of liquid into the stomach with the removal of material from the stomach. Optionally, stomach acid may be captured and returned to the stomach. Optionally, nutritional supplements or medicines may be added to the infused liquid. Optionally, a flush mount connectorized system with a built in valve may be used to simplify the interface with the gastrostomy hardware that remains installed in the patient. Optionally, the system may be configured to disable itself from further use after a triggering event (e.g., the passage of time or a predetermined number of uses) has occurred.
摘要翻译：当患者配备与胃的外部胃造口术连接时，摄取的食物可以通过胃造口术连接使用基于泵或虹吸管的系统去除，以实现体重减轻。通过将液体输送到胃中，通过从胃中去除材料可以改善去除摄取的食物的过程。任选地，胃酸可以被捕获并返回到胃。任选地，营养补充剂或药物可以加入到输注液体中。可选地，具有内置阀的嵌入式安装连接器系统可以用于简化与保持安装在患者体内的胃造口术硬件的界面。可选地，系统可以被配置为在触发事件（例如，时间的流逝或预定的使用次数）已经发生之后禁止其进一步使用。

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