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1. 发明申请

US20100291034A1 COMBINATIONS OF HCV PROTEASE INHIBITOR(S) AND CYP3A4 INHIBITOR(S), AND METHODS OF TREATMENT RELATED THERETO 审中-公开
标题翻译： HCV蛋白酶抑制剂（S）和CYP3A4抑制剂（S）的组合及其相关治疗方法
公开(公告)号：US20100291034A1
公开(公告)日：2010-11-18
申请号：US12839097
申请日：2010-07-19
申请人： Robert O RALSTON, II , Julie M. Strizki , Jaromir Vlach , Samir K. Gupta , Edward M. O'Mara, JR. , Anima Ghosal , Michelle A. Treitel , James F. McLeod , Ronald E. White
发明人： Robert O RALSTON, II , Julie M. Strizki , Jaromir Vlach , Samir K. Gupta , Edward M. O'Mara, JR. , Anima Ghosal , Michelle A. Treitel , James F. McLeod , Ronald E. White
IPC分类号： A61K38/21 , A61K38/05 , A61P31/14
CPC分类号： A61K31/496 , A61K31/16 , A61K31/192 , A61K31/395 , A61K31/40 , A61K31/403 , A61K31/427 , A61K31/4965 , A61K38/07 , A61K45/06 , A61K2300/00
摘要： Disclosed are medicaments, pharmaceutical compositions, pharmaceutical kits, and methods based on combinations comprising, separately or together: (a) a CYP3A4 inhibitor; and (b) a HCV protease inhibitor; for concurrent or consecutive administration in treating a human subject infected with HCV.
摘要翻译：公开了药物，药物组合物，药物试剂盒和基于组合的方法，所述组合包括，单独或一起：（a）CYP3A4抑制剂; 和（b）HCV蛋白酶抑制剂; 用于同时或连续给药以治疗感染HCV的人类受试者。

2. 发明授权

US06396893B1 Apparatus and method for adjusting the weight of a velocity limiter for a control rod of a nuclear reactor 有权
标题翻译：用于调节核反应堆控制棒的速度限制器的重量的装置和方法
公开(公告)号：US06396893B1
公开(公告)日：2002-05-28
申请号：US09427937
申请日：1999-10-27
申请人： Thomas F. Carter , James E. Holden , Richard E. Kingston , Gary S. Martin , John G. Pistolis , James F. McLeod , Michael J. Sullivan
发明人： Thomas F. Carter , James E. Holden , Richard E. Kingston , Gary S. Martin , John G. Pistolis , James F. McLeod , Michael J. Sullivan
IPC分类号： G21C7113
CPC分类号： G21C7/113 , G21Y2002/304 , G21Y2002/306 , G21Y2004/30 , G21Y2004/403 , Y02E30/39
摘要： The control rod includes an upper absorber section and a lower velocity limiter comprised of a socket, a vane, a transition piece and a set of fins. To adjust the weight of the control rod, lighter and heavier sets of fins, as well as lighter and heavier transition pieces are provided. By suitable selection of the lighter and heavier sets of fins and the lighter and heavier transition pieces, the weight of the velocity limiter can be selectively adjusted in accordance with the weights of differently designed sections to obtain a predetermined control rod weight. Additionally, the heavier transition piece may have material removed therefrom to decrease its weight to provide an infinite adjustment of weight within a predetermined range of weights for the velocity limiter.
摘要翻译：控制杆包括上部吸收器部分和由插座，叶片，过渡件和一组翅片组成的下限速器。为了调整控制杆的重量，提供更轻更重的散热片，以及较轻和较重的过渡件。通过适当选择较轻和较重的翅片组以及较轻和较重的过渡件，速度限制器的重量可根据不同设计部分的重量进行选择性调节，以获得预定的控制杆重量。此外，较重的过渡件可以具有从其中移除的材料以减小其重量，以在速度限制器的预定重量范围内提供无限的重量调节。

3. 发明授权

US6111600A Extended-reach sewer inspection device 失效
标题翻译：延伸下水道检查装置
公开(公告)号：US6111600A
公开(公告)日：2000-08-29
申请号：US41358
申请日：1998-02-26
申请人： James F. McLeod , Thomas A. Johnson
发明人： James F. McLeod , Thomas A. Johnson
IPC分类号： B08B9/04 , E03F7/12 , H04N7/18
CPC分类号： E03F7/12 , B08B9/0495
摘要： An extended-reach sewer inspection device involving a hose-driven apparatus for progressively inspecting and cleaning the inside of a pipe at remote locations. The apparatus is comprised of a hose that has a nozzle apparatus which includes rearwardly-directed non-axial orifices such nozzle is attached to a forwardly-extending axially-aligned male member that has a female proximal end connected to the hose and a distal end opposite of the hose. A skid that includes a central body with at least three pipe-engaging runners connected to it and an axially-aligned opening dimensioned to freely receive the male member in such a manner as to allow the member to rotate freely within the skid. A retainer is secured to the distal end of the male member to hold it in the central-body opening, and a video camera is affixed to the central body whereby non-rotating video images are available to assist in the inspection and cleaning of a pipe.
摘要翻译：一种延伸的下水道检查装置，其包括用于逐步检查和清洁远程位置的管道内部的软管驱动装置。该装置由具有喷嘴装置的软管组成，该喷嘴装置包括向后定向的非轴向孔，该喷嘴连接到前向延伸的轴向对准的阳构件，该阳构件具有连接到软管的阴性近端和与软管相对的远端的软管。包括具有与其连接的至少三个管接合流道的中心主体和一个轴向对准的开口，该开口的尺寸适于以允许构件在滑道内自由旋转的方式自由地容纳阳构件。保持器固定到阳构件的远端以将其保持在中心体开口中，并且将摄像机固定到中心体，由此可以使非旋转视频图像有助于检查和清洁管道。

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