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1. 发明申请

US20060142196A1 Uses of GDNF and GDNF receptor 有权
公开(公告)号：US20060142196A1
公开(公告)日：2006-06-29
申请号：US11336555
申请日：2006-01-20
申请人： Robert Klein , Mark Moore , Arnon Rosenthal , Anne Ryan
发明人： Robert Klein , Mark Moore , Arnon Rosenthal , Anne Ryan
IPC分类号： A61K38/17 , C07K14/705 , C07H21/04 , C12P21/06
CPC分类号： C07K14/71 , A01K2217/05 , A61K38/00 , C07K16/22 , C07K2319/00
摘要： GDNFRα, GDNFRα extracellular domain (ECD), GDNFRα variants, chimeric GDNFRα (e.g., GDNFRα immunoadhesin), and antibodies which bind thereto (including agonist and neutralizing antibodies) are disclosed. Various uses for these molecules are described, including methods to modulate cell activity and survival by response to GDNFRα-ligands, for example GDNF, by providing GDNFRα to the cell. Also provided are methods for using GDNFRα, GDNF, or agonists thereof, separately or in complex, to treat kidney diseases.

2. 发明申请

US20070233199A1 Communicating Medical Event Information 审中-公开
标题翻译：沟通医疗事件信息
公开(公告)号：US20070233199A1
公开(公告)日：2007-10-04
申请号：US11758533
申请日：2007-06-05
申请人： Mark Moore , Ward Silver
发明人： Mark Moore , Ward Silver
IPC分类号： A61N1/39
CPC分类号： A61N1/3925 , A61B5/002 , G06F19/3418 , G06F19/3481 , G16H40/63 , Y10S128/903
摘要： In general, the invention provides techniques for wireless communication of medical event information between medical devices that treat a particular patient. In general, medical event information describes the condition and treatment of a patient. A medical device may detect another medical device via a wireless communications medium, and establish a local wireless communication session the other device in order to receive medical event information stored by the other device for a patient. The wireless communications medium may be a radio frequency communications medium, and the medical devices may establish a local wireless communication session according to any of a number of local wireless data communication standards. The medical event information received from the other medical device may be used to select a therapy, or to generate a report or patient chart detailing the condition and treatment of the patient.
摘要翻译：通常，本发明提供了用于在治疗特定患者的医疗装置之间进行医疗事件信息的无线通信的技术。一般来说，医疗事件信息描述患者的状况和治疗。医疗设备可以经由无线通信介质检测另一医疗设备，并且建立另一设备的本地无线通信会话，以便接收另一设备为患者存储的医疗事件信息。无线通信介质可以是射频通信介质，并且医疗设备可以根据多个本地无线数据通信标准中的任何一个建立本地无线通信会话。从其他医疗装置接收到的医疗事件信息可以用于选择治疗，或者生成详细描述病人的状况和治疗的报告或患者图。

3. 发明申请

US20070025738A1 Communications systems and methods 审中-公开
标题翻译：通信系统和方法
公开(公告)号：US20070025738A1
公开(公告)日：2007-02-01
申请号：US11222047
申请日：2005-09-09
申请人： Mark Moore
发明人： Mark Moore
IPC分类号： H04B10/04
CPC分类号： H04B10/1149
摘要： This invention relates to systems and methods for wireless and wired optical data communications, in particular infrared data communications using techniques borrowed ultra wideband (UWB) radio. Data is input for communication. The data defines a plurality of data symbols for transmission. Each the data symbol is encoded onto first and second optical carriers. The encoding comprises encoding each of the data symbols as respective first and second pulse packets each comprising at least one optical pulse. The encoding uses a common pulse packet position modulation for the first and second carriers. The first and second optical carriers have respective first and second optical wavelengths. An optical signal comprising the first and second optical carriers is transmitted, received, and decoded to recover the data symbols.
摘要翻译：本发明涉及用于无线和有线光数据通信的系统和方法，特别是使用借用超宽带（UWB）无线电技术的红外数据通信。输入数据进行通讯。数据定义了用于传输的多个数据符号。每个数据符号被编码在第一和第二光载波上。编码包括将每个数据符号编码为各自包括至少一个光脉冲的第一和第二脉冲分组。编码对第一和第二载波使用公共脉冲分组位置调制。第一和第二光学载体具有相应的第一和第二光学波长。包括第一和第二光载波的光信号被发送，接收和解码以恢复数据符号。

4. 发明申请

US20060156426A1 Transgenic mice containing ABC transporter-like ATPase gene disruptions 审中-公开
标题翻译：含ABC转运蛋白的ATPase基因破坏的转基因小鼠
公开(公告)号：US20060156426A1
公开(公告)日：2006-07-13
申请号：US11369694
申请日：2006-03-06
申请人： Keith Allen , Mark Moore
发明人： Keith Allen , Mark Moore
IPC分类号： A01K67/027
CPC分类号： C07K14/705 , A01K2217/05 , A61K38/00
摘要： The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in an ABC transporter-like ATPase gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
摘要翻译：本发明涉及转基因动物，以及与基因功能表征相关的组合物和方法。具体地，本发明提供了包含ABC转运蛋白样ATP酶基因突变的转基因小鼠。这样的转基因小鼠可用作疾病的模型并用于鉴定调节基因表达和基因功能的试剂，以及作为各种疾病状态和疾病状况的潜在治疗。

5. 发明申请

US20060075512A1 Transgenic mice containing PAFR gene disruptions 审中-公开
公开(公告)号：US20060075512A1
公开(公告)日：2006-04-06
申请号：US11284710
申请日：2005-11-21
申请人： Thomas Brennan , William Matthews , Mark Moore
发明人： Thomas Brennan , William Matthews , Mark Moore
IPC分类号： A01K67/027 , C12N5/06
CPC分类号： C12N15/8509 , A01K67/0276 , A01K2217/072 , A01K2217/075 , A01K2217/20 , A01K2227/105 , A01K2267/03 , A01K2267/0393 , C12N2800/30
摘要： The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a platelet-activating factor receptor gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.

6. 发明申请

US20050164666A1 Communication methods and apparatus 审中-公开
标题翻译：沟通方法和设备
公开(公告)号：US20050164666A1
公开(公告)日：2005-07-28
申请号：US10475721
申请日：2003-09-24
申请人： Jack Lang , Mark Moore , Tim Starkie
发明人： Jack Lang , Mark Moore , Tim Starkie
IPC分类号： H01P3/00 , H04B1/69 , H04B3/54 , H04B7/00
CPC分类号： H04B1/7163 , H04B1/719 , H04B2203/54
摘要： This invention generally relates to methods and apparatus for radio frequency communications over mains power cabling and other wiring, in particular communications at microwave frequencies. Embodiments of the invention are particularly suitable for ultra wideband (UWB) communications. A method of communicating a microwave signal having a frequency of 1 GHz or higher using a cable comprising at least one conductor, the method comprising: positioning a transmit antenna at a transmission point on said cable at a distance from said cable to couple said microwave signal into said cable; driving said transmit antenna with said microwave signal to induce onto said cable a propagating wave to propagate along said cable; positioning a receive antenna to receive an electromagnetic signal generated by said propagating wave; receiving a version of said microwave signal using said receive antenna
摘要翻译：本发明一般涉及用于通过电力电力布线和其它布线的射频通信的方法和装置，特别是在微波频率下的通信。本发明的实施例特别适用于超宽带（UWB）通信。一种使用包括至少一个导体的电缆传送具有1GHz或更高频率的微波信号的方法，所述方法包括：将距离所述电缆一定距离处的所述电缆上的传输点处的发射天线定位以耦合所述微波信号进入电缆; 用所述微波信号驱动所述发射天线，以在所述电缆上诱导传播波沿着所述电缆传播; 定位接收天线以接收由所述传播波产生的电磁信号; 使用所述接收天线接收所述微波信号的版本

7. 发明申请

US20050031021A1 Communications systems and methods 审中-公开
标题翻译：通信系统和方法
公开(公告)号：US20050031021A1
公开(公告)日：2005-02-10
申请号：US10893540
申请日：2004-07-19
申请人： David Baker , Mark Moore
发明人： David Baker , Mark Moore
IPC分类号： H04B1/69 , H04B1/707
CPC分类号： H04B1/7183 , H04B1/71637 , H04B1/719
摘要： This invention generally relates to wired and wireless ultra wideband (UWB) data communications apparatus and methods, and in particular to UWB receiver systems and architectures, and to UWB transmission systems and signals. A UWB receiver system for receiving a UWB signal comprising a plurality of pulses, the system comprising: a receiver front end to receive a UWB signal; a reference UWB signal store for storing a reference UWB signal; and a correlator configured to correlate said received UWB signal with a plurality of differently delayed versions of said stored reference signal to co-determine a timing and a phase of a received UWB signal pulse; whereby a UWB signal carrying data encoded by both pulse position and pulse phase is decodeable.
摘要翻译：本发明一般涉及有线和无线超宽带（UWB）数据通信装置和方法，特别是涉及UWB接收机系统和体系结构以及UWB传输系统和信号。一种用于接收包括多个脉冲的UWB信号的UWB接收机系统，所述系统包括：接收器前端以接收UWB信号; 用于存储参考UWB信号的参考UWB信号存储器; 以及相关器，被配置为将所述接收的UWB信号与所述存储的参考信号的多个不同延迟的版本相关，以共同确定接收的UWB信号脉冲的定时和相位; 由此携带由脉冲位置和脉冲相位编码的数据的UWB信号是可解码的。

8. 发明授权

US06533736B1 Wireless medical stethoscope 失效
标题翻译：无线医疗听诊器
公开(公告)号：US06533736B1
公开(公告)日：2003-03-18
申请号：US09579486
申请日：2000-05-30
申请人： Mark Moore
发明人： Mark Moore
IPC分类号： A61B704
CPC分类号： A61B7/04
摘要： A wireless stethoscopic apparatus is disclosed comprising of an auscultation piece removably secured to a hearing piece. The components, auscultation piece and hearing piece, when not in use can be stored in a carrying case. Housed within the auscultation piece is a conventional radio frequency chip including a microphone that will enable transmission of radio frequency without the use of wires. A transmission system is housed within the auscultation piece, while the hearing piece includes a link manager receiver device for receiving the radio signals wirelessly from the transmission system and enabling sound to be heard via the hearing device from the auscultation piece.
摘要翻译：公开了一种无线听诊器，其包括可拆卸地固定在听力器上的听诊部件。组件，听诊片和听力片在不使用时可以存放在手提箱中。听诊器内的传统射频芯片包括麦克风，无需使用电线即可实现无线电频率的传输。传输系统容纳在听诊片内，而听筒包括用于从传输系统无线地接收无线电信号的链路管理器接收机设备，并且能够通过听觉设备从听诊片听到声音。

9. 发明授权

US10213362B2 Portable hydro-thermal therapy system for use with a vessel for containing water and method for use of same 有权
公开(公告)号：US10213362B2
公开(公告)日：2019-02-26
申请号：US13776624
申请日：2013-02-25
申请人： Mark Moore , Walter Abercrombie
发明人： Mark Moore , Walter Abercrombie
IPC分类号： A61H33/00 , A61F7/00
摘要： A portable hydro-thermal therapy system for use with a vessel for containing water and method for use of the same are disclosed. In one embodiment, the portable hydro-thermal therapy system includes a mobile trailer having a platform to achieve point-to-point haulage thereof. A cool water supply device having inlet and outlet port is mounted on the platform. The cool water supply device includes a water circulation path from the inlet port to the outlet port, a water pump coupled to the water circulation path, and a refrigeration cycle contained within the cool water supply device. A thermostat and water pump may cooperate in combination to provide water between about 50° F. and about 55° F. The water circulation path is thermally proximate to the evaporator coil in order to cool the water being pumped through the water circulation path to and from the vessel by way of inlet and outlet tubing.

10. 发明授权

US09125743B2 Devitalization and recellularization of cartilage 有权
公开(公告)号：US09125743B2
公开(公告)日：2015-09-08
申请号：US11826523
申请日：2007-07-16
申请人： Silvia Sihui Chen , Xiaofei Qin , Jingsong Chen , Lloyd Wolfinbarger , Mark Moore , Rony Thomas , Alyce Linthurst Jones
发明人： Silvia Sihui Chen , Xiaofei Qin , Jingsong Chen , Lloyd Wolfinbarger , Mark Moore , Rony Thomas , Alyce Linthurst Jones
IPC分类号： A61F2/02 , A61F2/30 , A61F2/28 , A61F2/46 , A61L27/38 , A61L27/36 , A61F2/38
CPC分类号： A61F2/30756 , A61F2/28 , A61F2/3094 , A61F2/38 , A61F2/3859 , A61F2/4644 , A61F2002/2817 , A61F2002/2839 , A61F2002/30004 , A61F2002/30224 , A61F2002/30751 , A61F2002/30759 , A61F2002/30764 , A61F2002/4646 , A61F2002/4648 , A61F2002/4649 , A61F2230/0069 , A61F2250/0014 , A61L27/3612 , A61L27/3683 , A61L27/3804 , A61L27/3852 , A61L2430/06
摘要： The present invention is directed toward recellularizing a devitalized cartilage graft with viable recellularizable cells in vivo, in situ, or in vitro to render the tissue vital. The present invention is also directed toward repairing a cartilage defect and implanting a cartilage graft into a human or animal by crafting a cartilage matrix into individual grafts, disinfecting and cleaning the cartilage graft, applying a pretreatment solution to the cartilage graft, removing cellular debris using an extracting solution to produce a devitalized cartilage graft, recellularizing the devitalized cartilage graft, implanting the cartilage graft into the cartilage defect with or without an insertion device, and sealing the implanted cartilage graft with recipient tissue. The devitalized cartilage graft is optionally stored between the removing cellular debris and the recellularizing steps. The present invention is directed to both recellularized cartilage grafts as well as a process for recellularizing cartilage grafts.

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