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1. 发明申请

US20230129843A1 SEPARATE OPTOELECTRONIC SUBSTRATE 有权
公开(公告)号：US20230129843A1
公开(公告)日：2023-04-27
申请号：US18050258
申请日：2022-10-27
申请人： Robert Kalman , Yong Ma , Bardia Pezeshki , Alexander Tselikov , Cameron Danesh
发明人： Robert Kalman , Yong Ma , Bardia Pezeshki , Alexander Tselikov , Cameron Danesh
IPC分类号： G02B6/42 , H01L31/173
摘要： A parallel optical interconnect having an optoelectronic substrate connected to a transceiver electronics substrate is disclosed. The optoelectronic substrate may hold optical transmitters and receivers and be electrically connected to the transceiver electronics substrate that may hold transmitter and receiver circuitries. The two substrates may be electrically connected with each other by inter-substrate interconnects, and the optoelectronic substrate may have through-substrate vias connecting the transmitters and receivers to the inter-substrate interconnects.

2. 发明授权

US09322020B2 RNA interference mediated inhibition of isocitrate dehydrogenase (IDH1) gene expression 有权
标题翻译： RNA干扰介导的异柠檬酸脱氢酶（IDH1）基因表达的抑制
公开(公告)号：US09322020B2
公开(公告)日：2016-04-26
申请号：US14123822
申请日：2012-06-01
申请人： Yong Ma , Duncan Brown , Steven Bartz
发明人： Yong Ma , Duncan Brown , Steven Bartz
IPC分类号： C12N15/113 , C07H21/02
CPC分类号： C12N15/1137 , C07H21/02 , C12N2310/14 , C12N2310/315 , C12N2310/317 , C12N2310/321 , C12N2310/332 , C12N2310/3521 , C12N2310/3533 , C12Y101/01042 , C12N2310/322
摘要： The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of IDH1 and mutant IDH1 gene expression and/or activity, and/or modulate an IDH1 or mutant IDH1 gene expression pathway. Specifically, the invention relates to double-stranded nucleic acid molecules, including small nucleic acid molecules such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules, that are capable of mediating or that mediate RNA interference (RNAi) against IDH1 or mutant IDH1 gene expression.
摘要翻译：本发明涉及用于研究，诊断和治疗响应于IDH1和突变体IDH1基因表达和/或活性的调节和/或调节IDH1或突变体的性状，疾病和病症的化合物，组合物和方法 IDH1基因表达途径。具体地说，本发明涉及双链核酸分子，包括小核酸分子，如短干扰核酸（siNA），短干扰RNA（siRNA），双链RNA（dsRNA），微RNA（miRNA）和短发夹RNA（shRNA）分子，其能够介导或介导针对IDH1或突变体IDH1基因表达的RNA干扰（RNAi）。

3. 发明申请

US20150027656A1 Method for preparing low-cost clean steel 审中-公开
标题翻译：低成本清洁钢的制备方法
公开(公告)号：US20150027656A1
公开(公告)日：2015-01-29
申请号：US14384981
申请日：2012-03-13
申请人： Fuping Tang , Zhen Li , Xiaofeng Wang , Peng Fei , Jinsong Meng , Yue Zhang , Yong Ma , Wenzhong Wang , Zhiwen Zhang , Xiaohan Wang , Meng Guo , Zhigang Zhao , Yang Lin , Guoqiang Xin , Weizhi Yao
发明人： Fuping Tang , Zhen Li , Xiaofeng Wang , Peng Fei , Jinsong Meng , Yue Zhang , Yong Ma , Wenzhong Wang , Zhiwen Zhang , Xiaohan Wang , Meng Guo , Zhigang Zhao , Yang Lin , Guoqiang Xin , Weizhi Yao
IPC分类号： C21C7/064 , B22D11/00
CPC分类号： C21C7/064 , B22D11/001 , C21C1/025 , C21C5/35 , C21C5/36 , C21C7/0043 , C21C7/0068 , C21C7/0087 , C21C7/0645 , C21C7/072 , C21C7/10 , C21C2300/08
摘要： A method for preparing low-cost clean steel includes steps of: preliminarily desulfurizing iron melt: preliminarily desulfurizing in an iron melt channel during blast furnace tapping and during iron folding in an iron folding room, adding a desulfurizing ball into the iron melt during the blast furnace tapping or the iron folding; dephosphorizing and controlling sulfur: dephosphorizing and controlling sulfur during converter steelmaking, in such a manner that P≦0.014% and S≦0.004% during tapping; rapidly dephosphorizing by slag-forming: rapidly dephosphorizing by slag-forming during converter tapping, at a converter end point, controlling a C content at 0.02˜0.10%, adding a dephosphorizing ball through an alloy chute during the converter tapping, blowing argon and stirring at the same time; purifying steel melt during RH refining: adding a purifying ball at a late stage of the RH refining when a vacuum degree is at 66.7˜500 Pa; and continuously casting with whole-process protection.
摘要翻译：制备低成本清洁钢的方法包括以下步骤：预先将铁熔体脱硫：在高炉出钢期间和铁折叠期间在铁熔体通道中预先脱硫，在铁折叠室中铁折叠期间，在爆炸期间向铁熔体中加入脱硫球炉膛或熨斗折叠; 脱磷控制硫：在转炉炼钢过程中脱磷和控制硫，使得出钢时P＆lt; 0.014％和S＆NlE; 0.004％; 通过成渣快速脱磷：在转炉攻丝期间通过炉渣形成快速脱磷，在转炉终点，控制C含量为0.02〜0.10％，在转炉出料过程中加入脱磷球通过合金槽，吹氩并搅拌与此同时; 在RH精炼期间净化钢熔体：当真空度为66.7〜500Pa时，在RH精炼的后期添加净化球; 并持续铸造全过程保护。

4. 发明授权

US08770536B2 Clipping apparatus for expansion card 失效
标题翻译：缩放装置用于扩展卡
公开(公告)号：US08770536B2
公开(公告)日：2014-07-08
申请号：US13568202
申请日：2012-08-07
申请人： Cong-Xu Hu , Yu-Lan Liu , Yong Ma , Chao-Jie Cai
发明人： Cong-Xu Hu , Yu-Lan Liu , Yong Ma , Chao-Jie Cai
IPC分类号： A47B97/04
CPC分类号： G01R31/2808 , G01R1/0408
摘要： A clipping apparatus includes a base, a support bracket, a positioning member and a rotating arm. The support bracket is located on the base. The support bracket is oblique relative to the base and defines a sliding slot. The positioning member is slidably engaged in the sliding slot. A first end of the rotating arm is pivotably engaged with the base. A second end of the rotating arm, opposite to the first end, is secured to the positioning member. An angle defined between the base and the support bracket is adjustable when the positioning member is slid relative to the base.
摘要翻译：夹持装置包括基座，支撑托架，定位构件和旋转臂。支架位于底座上。支撑托架相对于基座倾斜并且限定滑动槽。定位构件可滑动地接合在滑动槽中。旋转臂的第一端与基座可枢转地接合。旋转臂的与第一端相对的第二端固定到定位构件。当定位构件相对于底座滑动时，限定在基部和支撑托架之间的角度是可调节的。

5. 发明授权

US08733858B2 Computer enclosure 有权
标题翻译：电脑外壳
公开(公告)号：US08733858B2
公开(公告)日：2014-05-27
申请号：US13562780
申请日：2012-07-31
申请人： Chao-Jie Cai , Wei Liang , Yong Ma , Yu-Lin Liu
发明人： Chao-Jie Cai , Wei Liang , Yong Ma , Yu-Lin Liu
IPC分类号： A47B81/00
CPC分类号： G06F1/188
摘要： A computer enclosure includes a computer case and a power supply tray. The computer case includes a side plate and a rear plate adjacent to the side plate. A clamping portion is located on the rear plate, and an opening is defined between the side plate and the rear plate. The power supply tray is attached to the opening and includes a clipping member. The clipping member includes a securing portion extending from the power supply tray and a clipping portion rotatably attached to the securing portion. The clipping portion is engaged with the clamping portion to secure the power supply tray to the computer case, and the clipping portion is rotatable relative to the rear plate to disengage the clipping portion from the clamping portion.
摘要翻译：计算机外壳包括电脑外壳和电源托盘。计算机外壳包括侧板和与侧板相邻的后板。夹紧部分位于后板上，并且在侧板和后板之间限定开口。供电托盘附接到开口并且包括夹持构件。夹持构件包括从电源托盘延伸的固定部分和可旋转地附接到固定部分的夹持部分。夹持部分与夹持部分接合，以将电源托盘固定到计算机机壳上，并且夹持部分可相对于后板旋转以使夹持部分与夹持部分脱离。

6. 发明授权

US08205779B2 Surgical stapler with tactile feedback system 有权
标题翻译：手术吻合器与触觉反馈系统
公开(公告)号：US08205779B2
公开(公告)日：2012-06-26
申请号：US12793300
申请日：2010-06-03
申请人： Yong Ma , Russell S. Heinrich
发明人： Yong Ma , Russell S. Heinrich
IPC分类号： B21J15/28 , B27F7/17 , A61B17/04 , A61B17/10
CPC分类号： A61B17/07207 , A61B34/76 , A61B2017/00022 , A61B2090/065
摘要： A surgical instrument comprising a handle portion, an elongated body portion extending distally from the handle portion, and a tool adjacent the distal portion of the elongated body portion and having at least one jaw movable to a clamping position to clamp tissue. A tactile feedback system includes an expandable member extending from the handle portion, the expandable member providing a tactile indicator of a tissue parameter of tissue clamped by the least one jaw.
摘要翻译：一种手术器械，包括手柄部分，从手柄部分向远端延伸的细长主体部分和与细长主体部分的远端部分相邻的工具，并且具有至少一个可移动到夹紧位置以夹紧组织的钳口。触觉反馈系统包括从手柄部分延伸的可扩张构件，可扩张构件提供由至少一个钳夹住的组织的组织参数的触觉指示器。

7. 发明申请

US20110218550A1 SYSTEM AND METHOD FOR DETERMINING AND ADJUSTING POSITIONING AND ORIENTATION OF A SURGICAL DEVICE 审中-公开
标题翻译：用于确定和调整手术装置的定位和方向的系统和方法
公开(公告)号：US20110218550A1
公开(公告)日：2011-09-08
申请号：US13024583
申请日：2011-02-10
申请人： Yong Ma
发明人： Yong Ma
IPC分类号： A61B19/00
CPC分类号： A61B17/07207 , A61B2017/2929 , A61B2090/0811
摘要： A system and method including an elongate member having a proximal end and a distal end, the elongate member defining a longitudinal axis and configured to rotate relative to the longitudinal axis is presented. The instrument further includes a handle member configured to be attached to the proximal end of the elongate member, the handle member operatively associated with a rotation mechanism. The instrument also includes an end effector configured to be attached to the distal end of the elongate member, the end effector operatively associated with an articulation mechanism and configured to be pivotable throughout a plurality of directions relative to the longitudinal axis of the elongate member. A software algorithm is used to identify, track, and control directional movement of the end effector in accordance with rotational movement of the elongate member.
摘要翻译：提供了一种包括具有近端和远端的细长构件的系统和方法，细长构件限定纵向轴线并且被配置为相对于纵向轴线旋转。仪器还包括构造成附接到细长构件的近端的手柄构件，手柄构件与旋转机构可操作地相关联。仪器还包括端部执行器，其构造成附接到细长构件的远端，该端部执行器与关节运动机构可操作地相关联并且构造成能够相对于细长构件的纵向轴线在多个方向上枢转。软件算法用于根据细长构件的旋转运动识别，跟踪和控制末端执行器的定向运动。

8. 发明申请

US20110218400A1 SURGICAL INSTRUMENT WITH INTEGRATED WIRELESS CAMERA 审中-公开
标题翻译：具有集成无线摄像机的外科仪器
公开(公告)号：US20110218400A1
公开(公告)日：2011-09-08
申请号：US13025186
申请日：2011-02-11
申请人： Yong Ma , James Power
发明人： Yong Ma , James Power
IPC分类号： A61B1/05
CPC分类号： A61B1/05
摘要： A surgical instrument including an integrated wireless camera includes a handle assembly housing control circuitry. An elongated shaft extends from the handle assembly and includes an end effector disposed at a distal end thereof. An image sensor assembly is disposed toward the distal end of the elongated shaft and is electrically coupled to the control circuitry. The image sensor assembly is configured to convert an optical image into an electrical signal and communicate the electrical signal to the control circuitry. The control circuitry is configured to process the signal and wirelessly transmit the processed signal to a wireless receiver positioned remote of the surgical instrument.
摘要翻译：包括集成无线照相机的手术器械包括手柄组件壳体控制电路。细长轴从手柄组件延伸并且包括设置在其远端处的末端执行器。图像传感器组件朝向细长轴的远端设置并且电耦合到控制电路。图像传感器组件被配置为将光学图像转换成电信号并将电信号传送到控制电路。控制电路被配置为处理该信号并将经处理的信号无线传送到位于该外科器械远端的无线接收器。

9. 发明授权

US06211296B1 Hydrogels containing substances 失效
公开(公告)号：US06211296B1
公开(公告)日：2001-04-03
申请号：US09430044
申请日：1999-10-29
申请人： Dean M. Frate , Joseph A. Chiarelli , Yong Ma
发明人： Dean M. Frate , Joseph A. Chiarelli , Yong Ma
IPC分类号： C08L3302
CPC分类号： A61K9/7023 , Y10S524/916
摘要： A blend of one or more crosslinked polymers or copolymers prepared from an olefinically unsaturated polymerizable carboxylic or anhydride monomer and at least one high molecular weight essentially linear polymer prepared from an olefinically unsaturated polymerizable carboxylic acid monomer. The blend is neutralized to typically a low pH, and generally contains a noncovalent, e.g. ionic, crosslinking agent, and a cure rate modifier. The hydrogel blend is capable of containing a large amount of water, has good tack, good adhesion, and can be utilized as an application vehicle having a backing thereon as well as containing various substances such as personal care compounds, pharmaceuticals, active ingredients, and the like.

10. 发明申请

US20120255985A1 SURGICAL STAPLER WITH TACTILE FEEDBACK SYSTEM 有权
标题翻译：手术反馈系统
公开(公告)号：US20120255985A1
公开(公告)日：2012-10-11
申请号：US13493061
申请日：2012-06-11
申请人： Yong Ma , Russell S. Heinrich
发明人： Yong Ma , Russell S. Heinrich
IPC分类号： A61B17/068 , A61B17/29
CPC分类号： A61B17/07207 , A61B34/76 , A61B2017/00022 , A61B2090/065
摘要： A surgical instrument comprising a handle portion, an elongated body portion extending distally from the handle portion, and a tool adjacent the distal portion of the elongated body portion and having at least one jaw movable to a clamping position to clamp tissue. A tactile feedback system includes an expandable member extending from the handle portion, the expandable member providing a tactile indicator of a tissue parameter of tissue clamped by the least one jaw.
摘要翻译：一种手术器械，包括手柄部分，从手柄部分向远端延伸的细长主体部分和与细长主体部分的远端部分相邻的工具，并且具有至少一个可移动到夹紧位置以夹紧组织的钳口。触觉反馈系统包括从手柄部分延伸的可扩张构件，可扩张构件提供由至少一个钳夹住的组织的组织参数的触觉指示器。

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