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1. 发明申请

US20070254917A1 INTRACELLULAR RECEPTOR MODULATOR COMPOUNDS AND METHODS 审中-公开
标题翻译：细胞内受体调节剂化合物和方法
公开(公告)号：US20070254917A1
公开(公告)日：2007-11-01
申请号：US11622997
申请日：2007-01-12
申请人： Robert Higuchi , Steven Roach , Lin Zhi , Mark Adams , Yan Liu , Donald Karanewsky , Andrew Hudson
发明人： Robert Higuchi , Steven Roach , Lin Zhi , Mark Adams , Yan Liu , Donald Karanewsky , Andrew Hudson
IPC分类号： C07D215/00 , A61K31/47 , A61P1/00 , A61P11/00 , A61P17/00 , A61P25/00 , G01N33/569 , C07D215/20 , A61P3/00 , A61P35/00 , A61P37/00 , A61P9/00
CPC分类号： C07D215/18 , C07D401/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04
摘要： This invention relates to compounds that bind to intracellular receptors and/or modulate activity of intracellular receptors, and to methods for making and using such compounds.
摘要翻译：本发明涉及结合细胞内受体和/或调节细胞内受体活性的化合物，以及制备和使用这些化合物的方法。

2. 发明申请

US20200032004A1 ADDITIVE MANUFACTURING SUPPORT MATERIAL 审中-公开
公开(公告)号：US20200032004A1
公开(公告)日：2020-01-30
申请号：US16603158
申请日：2018-04-05
申请人： Andrew Hudson , Thomas Hinton , Adam Feinberg , Andrew Lee
发明人： Andrew Hudson , Thomas Hinton , Adam Feinberg , Andrew Lee
IPC分类号： C08J3/075 , B33Y70/00 , C09D11/04
摘要： This document describes a process of producing gel microparticles, which are consistent in size and morphology. Through the process of coacervation, large volumes of gel microparticle slurry can be produced by scaling up reactor vessel size. Particles can be repeatedly dehydrated and rehydrated in accordance to their environment, allowing for the storage of particles in a non-solvent such as ethanol. Gel slurries exhibit a Bingham plastic behavior in which the slurry behaves as a solid at shear stresses that are below a critical value. Upon reaching the critical shear stress, the slurry undergoes a rapid decrease in viscosity and behaves as a liquid. The rheological behavior of these slurries can be adjusted by changing the compaction processes such as centrifugation force to alter the yield-stress. The narrower distribution and reduced size of these particles allows for an increase in FRESH printing fidelity.

3. 发明申请

US20070265429A1 Use of a vibratory spiral elevator for crystallizing and/or drying of plastic pellets 审中-公开
标题翻译：使用振动螺旋升降机来结晶和/或干燥塑料颗粒
公开(公告)号：US20070265429A1
公开(公告)日：2007-11-15
申请号：US11431770
申请日：2006-05-10
申请人： Andrew Hudson
发明人： Andrew Hudson
IPC分类号： B29C47/88
CPC分类号： B29B9/16 , B29B9/065 , B29B13/065 , B29B2009/165 , B65G27/02 , F26B17/266
摘要： A method and system for processing a polymer includes providing a molten polymer and processing the polymer into malleable components for delivery to a spirally wound conveying surface. Vibratory forces may be utilized to urge the components along the length of the conveying surface as they undergo crystallizing or drying or crystallizing and drying. Additional supplemental temperature control may be employed to affect crystallization and/or drying of the components along the conveying surface.
摘要翻译：用于处理聚合物的方法和系统包括提供熔融聚合物并将聚合物加工成可延展的部件以递送到螺旋卷绕的输送表面。当经历结晶或干燥或结晶和干燥时，可以利用振动力沿着输送表面的长度推动部件。可以使用附加的补充温度控制来影响沿输送表面的部件的结晶和/或干燥。

4. 发明授权

US4636438A Masking films 失效
标题翻译：掩蔽片
公开(公告)号：US4636438A
公开(公告)日：1987-01-13
申请号：US741645
申请日：1985-06-05
申请人： Andrew Hudson , Norman J. Stansfield
发明人： Andrew Hudson , Norman J. Stansfield
IPC分类号： B32B27/36 , B05D1/32 , B32B27/40 , C08J7/04 , C09D175/06 , G03F1/00 , B32B27/08
CPC分类号： G03F1/68 , B05D1/325 , C08J7/047 , C09D175/06 , Y10T428/31507 , Y10T428/31551 , Y10T428/31565 , Y10T428/31786 , Y10T428/31797
摘要： Masking films comprise a transparent base, preferably a polyester or a polycarbonate, directly carrying a masking film in the form of a dyed transparent plastics material based upon a vinyl chloride-vinyl acetate copolymer coating, which contains an aromatic polyester-based polyurethane. The amount of vinyl acetate and polyurethane in the coating preferably comprises 30% to 65% w/w of its total polymer content.
摘要翻译：遮蔽膜包括透明基材，优选聚酯或聚碳酸酯，其基于含有芳族聚酯基聚氨酯的氯乙烯 - 乙酸乙烯酯共聚物涂层直接携带以染色的透明塑料材料形式的掩蔽膜。涂层中的乙酸乙烯酯和聚氨酯的量优选包含其总聚合物含量的30％至65％w / w。

5. 发明授权

US4588674A Laser imaging materials comprising carbon black in overlayer 失效
标题翻译：包含炭黑的激光成像材料
公开(公告)号：US4588674A
公开(公告)日：1986-05-13
申请号：US541734
申请日：1983-10-13
申请人： Malcolm J. Stewart , Andrew Hudson , Peter W. Griffiths
发明人： Malcolm J. Stewart , Andrew Hudson , Peter W. Griffiths
IPC分类号： B41M5/26 , B41M5/395 , G03F1/00 , G03C1/72 , G01D9/00 , G03F7/26
CPC分类号： B41M5/395 , G03F1/68 , Y10S430/165
摘要： The laser imaging material comprises a laser-transparent support layer of, for example, polyester. A first overlying layer is laser-transparent and formed from a binder that is instantaneously thermally-chemically-decomposable with the production of a gas, for example, an acrylic or methacrylic homopolymer or copolymer, a cellulosic polymer, or a homopolymer or copolymer of stryene. A second overlying layer is formed from such a material, the same as or different from that of the first overlying layer, pigmented with carbon black. Upon laser irradiation through the support layer 10, selected portions of the carbon black are transferred to a suitable receptor surface such as paper or a lithographic plate.
摘要翻译：激光成像材料包括例如聚酯的激光透明支撑层。第一覆盖层是激光透明的并且由粘合剂形成，所述粘合剂通过产生气体瞬时热化学分解，例如丙烯酸或甲基丙烯酸均聚物或共聚物，纤维素聚合物，或苯乙烯均聚物或共聚物。第二覆盖层由与碳黑着色的第一覆盖层的材料相同或不同的材料形成。当通过支撑层10进行激光照射时，将炭黑的选定部分转移到合适的受体表面，例如纸或平版印刷版。

6. 发明授权

US08413763B2 Firefighters tracer line apparatus 有权
标题翻译：消防员示踪线设备
公开(公告)号：US08413763B2
公开(公告)日：2013-04-09
申请号：US12731064
申请日：2010-03-24
申请人： Ronald William Hermann , Andrew Hudson , Caralin Adair
发明人： Ronald William Hermann , Andrew Hudson , Caralin Adair
IPC分类号： A62B35/00
CPC分类号： A62B99/00 , A62B3/00
摘要： A rescue line apparatus is configured as a horizontal tether for being readily connected between a door and a portion of the door jamb or other entry location and extending a line as the user moves within the structure. The device allows the user to readily locate their way back for egressing the structure, and can be readily disengaged by the user, which activates a braking system that prevents unit “run-away”. A multi-attach anchor head couples the far end of the line to any desired structure, and has a beacon assembly which outputs a light pattern of sufficient brightness to be seen by the user when visually locating their attachment point within the structure. A multi-element visual indicator is configured for indicating line extension distance, and displaying tether line status. Many options promote safety and a fully cooperative environment.
摘要翻译：救援线装置被构造为水平系绳，用于容易地连接在门与门侧柱或其他入口位置的一部分之间，并且随着使用者在结构内移动而延伸线。该设备允许用户容易地定位他们的方式以退出结构，并且可以容易地被用户脱离，这激活了防止单元逃跑的制动系统。多连接锚头将线的远端耦合到任何期望的结构，并且具有信标组件，其输出足够亮度的光图案，以在用户可视地将其附接点定位在结构内时被使用者看到。多元素视觉指示器被配置为指示线路延伸距离，并显示系绳线路状态。许多选择促进安全和充分合作的环境。

7. 发明授权

US07666355B2 Automated analyzer 失效
标题翻译：自动分析仪
公开(公告)号：US07666355B2
公开(公告)日：2010-02-23
申请号：US11369204
申请日：2006-03-07
申请人： Tino Alavie , Keith Beckley , Andrew Hudson , Stephen W. Leonard , Robert Maaskant , Samad Talebpour , William Yang
发明人： Tino Alavie , Keith Beckley , Andrew Hudson , Stephen W. Leonard , Robert Maaskant , Samad Talebpour , William Yang
IPC分类号： G01N21/00
CPC分类号： G01N35/0092 , G01N21/253 , G01N35/028 , G01N35/109 , G01N2001/288 , G01N2035/00326 , G01N2035/0422 , G01N2035/0465 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/2575
摘要： The present invention provides a bar-code driven, completely automated, microplate-based analyzer system for performing chemical, biochemical or biological assays. The analyzer is a modular, bench-top instrument that compactly integrates subsystems for sample dispensing, liquid handling, microplate transport, thermal incubation, vortexing, solid phase separation and optical reading. An internal processor is included for automating the instrument, and a user interface to facilitate communication with the operator via a touch-sensitive liquid-crystal display (LCD), and communicating with a remote network via multiple protocols. The analyzer includes firmware resident within the processing system and the user interface allows the operator to select pre-defined assay batch protocols and the user interface is configured in such as way so as to restrict an operator from programming the firmware.
摘要翻译：本发明提供了用于进行化学，生物化学或生物测定的条形码驱动的，完全自动化的基于微孔板的分析仪系统。分析仪是一种模块化的台式仪器，可紧凑集成样品分配，液体处理，微孔板输送，热孵育，涡旋，固相分离和光学读取的子系统。包括用于使仪器自动化的内部处理器，以及用于通过触敏液晶显示器（LCD）促进与操作者通信的用户接口，以及经由多个协议与远程网络通信。分析器包括驻留在处理系统内的固件，用户界面允许操作员选择预定义的测试批处理协议，并且用户界面被配置为以限制操作者编程固件的方式。

8. 发明申请

US20090164775A1 Broadband computer system 审中-公开
标题翻译：宽带电脑系统
公开(公告)号：US20090164775A1
公开(公告)日：2009-06-25
申请号：US12000965
申请日：2007-12-19
申请人： Andrew Holmes , Andrew Hudson
发明人： Andrew Holmes , Andrew Hudson
IPC分类号： H04L9/00
CPC分类号： G06F21/62 , G06F21/34 , H04L63/0428 , H04L63/08 , H04L63/166
摘要： A broadband computer system comprising a network, a client computer comprising a secure log-on means, a user interaction means, a display means, processing means and client data storage means, wherein applications used on the client computer are stored on the client data storage means; a server connected to the network comprising a secure log-on verification means and server data storage means, wherein the secure log-on means communicates with the secure log-on verification means across the network to authenticate a user and, after authentication, the processing means of the client computer provides a suite of applications for use by the user and wherein any user data required by the suite of applications is provided across the network by the server data storage means.
摘要翻译：包括网络的宽带计算机系统，包括安全登录装置的客户端计算机，用户交互装置，显示装置，处理装置和客户端数据存储装置，其中在客户端计算机上使用的应用程序存储在客户端数据存储器手段; 连接到网络的服务器，包括安全登录验证装置和服务器数据存储装置，其中安全登录装置通过网络与安全登录验证装置通信以认证用户，并且在认证之后，处理客户端计算机的装置提供一组用户使用的应用程序，并且其中由应用套件所需的任何用户数据由服务器数据存储装置跨网络提供。

9. 发明申请

US20060210435A1 Automated analyzer 失效
标题翻译：自动分析仪
公开(公告)号：US20060210435A1
公开(公告)日：2006-09-21
申请号：US11369204
申请日：2006-03-07
申请人： Tino Alavie , Keith Beckley , Andrew Hudson , Stephen Leonard , Robert Maaskant , Samad Talebpour , William Yang
发明人： Tino Alavie , Keith Beckley , Andrew Hudson , Stephen Leonard , Robert Maaskant , Samad Talebpour , William Yang
IPC分类号： G01N35/00
CPC分类号： G01N35/0092 , G01N21/253 , G01N35/028 , G01N35/109 , G01N2001/288 , G01N2035/00326 , G01N2035/0422 , G01N2035/0465 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/2575
摘要： The present invention provides a bar-code driven, completely automated, microplate-based analyzer system for performing chemical, biochemical or biological assays. The analyzer is a modular, bench-top instrument that compactly integrates subsystems for sample dispensing, liquid handling, microplate transport, thermal incubation, vortexing, solid phase separation and optical reading. An internal processor is included for automating the instrument, and a user interface to facilitate communication with the operator via a touch-sensitive liquid-crystal display (LCD), and communicating with a remote network via multiple protocols. The analyzer includes firmware resident within the processing system and the user interface allows the operator to select pre-defined assay batch protocols and the user interface is configured in such as way so as to restrict an operator from programming the firmware.
摘要翻译：本发明提供了用于进行化学，生物化学或生物测定的条形码驱动的，完全自动化的基于微孔板的分析仪系统。分析仪是一种模块化的台式仪器，可紧凑集成样品分配，液体处理，微孔板输送，热孵育，涡旋，固相分离和光学读取的子系统。包括用于使仪器自动化的内部处理器，以及用于通过触敏液晶显示器（LCD）促进与操作者通信的用户接口，以及经由多个协议与远程网络通信。分析器包括驻留在处理系统内的固件，用户界面允许操作员选择预定义的测试批处理协议，并且用户界面被配置为以限制操作者编程固件的方式。

10. 发明申请

US20060042113A1 Process for separating and drying thermoplastic particles under high pressure 有权
标题翻译：在高压下分离和干燥热塑性颗粒的方法
公开(公告)号：US20060042113A1
公开(公告)日：2006-03-02
申请号：US11134946
申请日：2005-05-23
申请人： Michael Ekart , Andrew Hudson , Raymond Isaac , Luciano Samitier
发明人： Michael Ekart , Andrew Hudson , Raymond Isaac , Luciano Samitier
IPC分类号： F26B17/24 , F26B17/30
CPC分类号： F26B7/00 , B29B9/065 , B29B9/16 , B29B2009/165 , F26B5/08
摘要： A process for feeding a slurry of thermoplastic synthetic polymer particles such as polyethylene terephthalate homopolymers and copolymers in combination with a liquid such as water at a liquid temperature greater than the normal boiling point of the liquid, under a pressure greater than the vapor pressure of the liquid at the liquid temperature, into a separation zone such as a centrifugal dryer, and within the separation zone: a. separating the liquid from the particles, and b. drying the particles; while under a high pressure equal to or greater than the vapor pressure of the liquid. There is also provided a process for decoupling the dried particles from the separation zone to an atmosphere having a pressure less than the vapor pressure of the liquid while maintaining the vapor pressure of the particles prior to decoupling equal to or above the vapor pressure of the liquid at the liquid temperature.
摘要翻译：在大于所述液体的蒸汽压的压力下，在大于所述液体的标准沸点的液体温度下，将诸如聚对苯二甲酸乙二醇酯均聚物和共聚物的热塑性合成聚合物颗粒的浆料与液体如水混合的方法，液体在液体温度下进入分离区如离心干燥器，并在分离区内：a。将液体与颗粒分离，b。干燥颗粒; 同时在等于或大于液体的蒸气压的高压下。还提供了一种将干燥颗粒从分离区分离到具有低于液体的蒸气压力的气氛的气氛的过程，同时在解耦之前保持颗粒的蒸气压等于或高于液体的蒸气压在液体温度下。

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