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1. 发明申请

US20100168660A1 Method and apparatus for determining and delivering a drug bolus 有权
标题翻译：用于确定和递送药物丸剂的方法和装置
公开(公告)号：US20100168660A1
公开(公告)日：2010-07-01
申请号：US12646336
申请日：2009-12-23
申请人： Paul J. Galley , Maury Zivitz , Stefan Weinert , Robert Hellwig
发明人： Paul J. Galley , Maury Zivitz , Stefan Weinert , Robert Hellwig
IPC分类号： A61M5/172 , A61B5/00 , G06F3/14
CPC分类号： A61B5/14532 , A61B5/7475 , A61M5/14244 , A61M5/172 , A61M2205/3569 , A61M2205/3592 , A61M2205/502 , A61M2209/01 , G06F1/1626 , G06F1/169 , G06F1/1698 , G06F19/00 , G06F19/3468
摘要： An electronic device may be configured to prompt a user via an on-board display to measure user glucose via an on-board glucose meter, to compute a first drug bolus value based on the measured user glucose, to display the first drug bolus value on the display and prompt the user via the display to enter carbohydrate information into the device, to compute a second drug bolus value based on the entered carbohydrate information, to display the second drug bolus value on the display and prompt the user via the display to enter user health information into the device, to compute a third drug bolus value based on the entered health information and a total drug bolus value as a sum of the first, second and third drug bolus values, and to display the third and total drug bolus values on the display.
摘要翻译：电子设备可以被配置为经由车载显示器提示用户经由车载葡萄糖计测量用户葡萄糖，以基于测量的用户葡萄糖来计算第一药物推注值，以显示第一药物推注值通过显示器显示并提示用户将碳水化合物信息输入到装置中，基于输入的碳水化合物信息计算第二次药物推注值，在显示器上显示第二次药物推注值，并通过显示器提示用户进入将用户健康信息输入到装置中，基于所输入的健康信息和总药物推注值作为第一，第二和第三药物推注值的总和来计算第三药物推注值，并显示第三和全部药物推注值在显示器上。

2. 发明授权

US07291107B2 Insulin bolus recommendation system 有权
标题翻译：胰岛素推注系统
公开(公告)号：US07291107B2
公开(公告)日：2007-11-06
申请号：US10927614
申请日：2004-08-26
申请人： Robert Hellwig , Stefan Weinert
发明人： Robert Hellwig , Stefan Weinert
IPC分类号： A61B5/00 , A61M31/00
CPC分类号： G06F19/3468 , A61M5/1723 , G06F19/00 , G16H10/60 , G16H15/00
摘要： A system for recommending insulin bolus quantities to an insulin user includes a display unit and memory unit coupled to a control circuit with a user blood glucose target stored in the memory unit. The control circuit is programmed to receive the user's current blood glucose value, to determine and display via the display unit a recommended correction insulin bolus quantity if the current blood glucose value exceeds the blood glucose target, to compute a difference value as the current blood glucose value less the blood glucose target, and to produce a modified blood glucose target as a sum of the blood glucose target and the difference value for a lock-out time period if the difference value is positive. Additional correction insulin bolus quantities may be recommended during the lock-out time period if the user's current blood glucose value exceeds the modified blood glucose target.
摘要翻译：用于向胰岛素用户推荐胰岛素推注量的系统包括显示单元和与存储在存储器单元中的用户血糖目标的控制电路耦合的存储单元。控制电路被编程为接收用户的当前血糖值，如果当前血糖值超过血糖目标，则通过显示单元确定和显示推荐的校正胰岛素推注量，以计算当前血糖值如果差值为正值，则减去血糖值，并产生修正的血糖目标作为血糖目标和锁定时间段的差值之和。如果用户的当前血糖值超过修正的血糖目标，则可以在锁定时间段期间推荐额外的校正胰岛素推注量。

3. 发明申请

US20060137695A1 System and method for determining insulin bolus quantities 有权
标题翻译：用于确定胰岛素推注量的系统和方法
公开(公告)号：US20060137695A1
公开(公告)日：2006-06-29
申请号：US11022100
申请日：2004-12-23
申请人： Robert Hellwig , Stefan Weinert
发明人： Robert Hellwig , Stefan Weinert
IPC分类号： A61B19/00
CPC分类号： G01N33/66 , A61M5/1413 , A61M2005/1405 , A61M2005/14208 , G01N33/74 , G01N2333/4745 , G01N2800/042 , G06F19/00 , G06F19/3468 , G16H50/50
摘要： A method of computing an insulin bolus quantity when a measured glucose value in a current time interval exceeds a target glucose value for the current time interval and when a time duration of glucose lowering action of the bolus to be administered spans the current and a number of the next adjacent time intervals, may comprise determining a corresponding number of percentages of insulin action of the recommended bolus quantity that will each be used lowering the glucose level during a respective one of the number of time intervals, and computing the recommended bolus quantity as a function of the measured glucose value, the target blood glucose level for a last one of the number of next adjacent time intervals, the insulin sensitivities for the current and each of the number of next adjacent time intervals, and the corresponding number of percentages.
摘要翻译：当当前时间间隔内的测量葡萄糖值超过当前时间间隔的目标葡萄糖值时，以及当要施用的推注的葡萄糖降低作用的持续时间跨越当前时间间隔和当前时间间隔的多个时，计算胰岛素推注量的方法下一个相邻的时间间隔可以包括确定推荐的推注剂量的胰岛素作用百分比的相应数量，其将在每个时间间隔的相应时间段内分别使用降低葡萄糖水平，并将推荐的推注量计算为测量的葡萄糖值的功能，下一个相邻时间间隔数量的最后一个的目标血糖水平，当前和下一个相邻时间间隔的数量的胰岛素敏感性以及相应的百分比数。

4. 发明申请

US20060047192A1 Insulin bolus recommendation system 有权
公开(公告)号：US20060047192A1
公开(公告)日：2006-03-02
申请号：US10927614
申请日：2004-08-26
申请人： Robert Hellwig , Stefan Weinert
发明人： Robert Hellwig , Stefan Weinert
IPC分类号： A61B5/00 , C12Q1/68
CPC分类号： G06F19/3468 , A61M5/1723 , G06F19/00 , G16H10/60 , G16H15/00
摘要： A system for recommending insulin bolus quantities to an insulin user includes a display unit and memory unit coupled to a control circuit with a user blood glucose target stored in the memory unit. The control circuit is programmed to receive the user's current blood glucose value, to determine and display via the display unit a recommended correction insulin bolus quantity if the current blood glucose value exceeds the blood glucose target, to compute a difference value as the current blood glucose value less the blood glucose target, and to produce a modified blood glucose target as a sum of the blood glucose target and the difference value for a lock-out time period if the difference value is positive. Additional correction insulin bolus quantities may be recommended during the lock-out time period if the user's current blood glucose value exceeds the modified blood glucose target.

5. 发明申请

US20090222247A1 SYSTEM FOR DETERMINING BASAL RATE PROFILES 审中-公开
标题翻译：用于确定基本速率轮廓的系统
公开(公告)号：US20090222247A1
公开(公告)日：2009-09-03
申请号：US12039366
申请日：2008-02-28
申请人： Robert Hellwig , Wim Van der Helm , Stefan Weinert
发明人： Robert Hellwig , Wim Van der Helm , Stefan Weinert
IPC分类号： G06G7/60
CPC分类号： G06F19/3456
摘要： A system and method are provided for generating a plurality of basal rate models that together model delivery of a corresponding plurality of basal rates of a diabetes treatment drug to a patient over a period of time. Information may be collected from a plurality of patients that have a diabetic condition and to which the diabetes treatment drug has been delivered. The collected information may include a glycemic control indicator for each of the plurality of patients that is indicative of an efficacy of the diabetes treatment drug in treating the patient's diabetic condition. The collected information may be filtered based on the glycemic control indicators to produce a subset of information that includes information only for patients that exhibit acceptable glycemic control. The plurality of basal rate models may be generated based on the subset of the collected information, and may be stored in a memory unit.
摘要翻译：提供了一种用于产生多个基础速率模型的系统和方法，所述基础速率模型一起在一段时间内向患者模拟糖尿病治疗药物的相应多个基础速率的递送。可以从具有糖尿病状况的多个患者中收集信息，并且已经递送了糖尿病治疗药物。收集的信息可以包括指示糖尿病治疗药物治疗患者的糖尿病状况的功效的多个患者中的每一个的血糖控制指示剂。所收集的信息可以基于血糖控制指示符进行过滤以产生信息子集，所述信息子集仅包括显示可接受的血糖控制的患者的信息。可以基于收集的信息的子集来生成多个基本速率模型，并且可以将其存储在存储器单元中。

6. 发明授权

US08118770B2 Reconciling multiple medical device bolus records for improved accuracy 有权
标题翻译：协调多个医疗设备推注记录，以提高准确性
公开(公告)号：US08118770B2
公开(公告)日：2012-02-21
申请号：US12646336
申请日：2009-12-23
申请人： Paul J. Galley , Maury Zivitz , Stefan Weinert , Robert Hellwig
发明人： Paul J. Galley , Maury Zivitz , Stefan Weinert , Robert Hellwig
IPC分类号： A61M31/00
CPC分类号： A61B5/14532 , A61B5/7475 , A61M5/14244 , A61M5/172 , A61M2205/3569 , A61M2205/3592 , A61M2205/502 , A61M2209/01 , G06F1/1626 , G06F1/169 , G06F1/1698 , G06F19/00 , G06F19/3468
摘要： An electronic device may be configured to prompt a user via an on-board display to measure user glucose via an on-board glucose meter, to compute a first drug bolus value based on the measured user glucose, to display the first drug bolus value on the display and prompt the user via the display to enter carbohydrate information into the device, to compute a second drug bolus value based on the entered carbohydrate information, to display the second drug bolus value on the display and prompt the user via the display to enter user health information into the device, to compute a third drug bolus value based on the entered health information and a total drug bolus value as a sum of the first, second and third drug bolus values, and to display the third and total drug bolus values on the display.
摘要翻译：电子设备可以被配置为经由车载显示器提示用户经由车载葡萄糖计测量用户葡萄糖，以基于测量的用户葡萄糖来计算第一药物推注值，以显示第一药物推注值通过显示器显示并提示用户将碳水化合物信息输入到装置中，基于输入的碳水化合物信息计算第二次药物推注值，在显示器上显示第二次药物推注值，并通过显示器提示用户进入将用户健康信息输入到装置中，基于所输入的健康信息和总药物推注值作为第一，第二和第三药物推注值的总和来计算第三药物推注值，并显示第三和全部药物推注值在显示器上。

7. 发明授权

US07869851B2 System and method for determining insulin bolus quantities 有权
标题翻译：用于确定胰岛素推注量的系统和方法
公开(公告)号：US07869851B2
公开(公告)日：2011-01-11
申请号：US11022100
申请日：2004-12-23
申请人： Robert Hellwig , Stefan Weinert
发明人： Robert Hellwig , Stefan Weinert
IPC分类号： A61B5/00
CPC分类号： G01N33/66 , A61M5/1413 , A61M2005/1405 , A61M2005/14208 , G01N33/74 , G01N2333/4745 , G01N2800/042 , G06F19/00 , G06F19/3468 , G16H50/50
摘要： A method of computing an insulin bolus quantity when a measured glucose value in a current time interval exceeds a target glucose value for the current time interval and when a time duration of glucose lowering action of the bolus to be administered spans the current and a number of the next adjacent time intervals, may comprise determining a corresponding number of percentages of insulin action of the recommended bolus quantity that will each be used lowering the glucose level during a respective one of the number of time intervals, and computing the recommended bolus quantity as a function of the measured glucose value, the target blood glucose level for a last one of the number of next adjacent time intervals, the insulin sensitivities for the current and each of the number of next adjacent time intervals, and the corresponding number of percentages.
摘要翻译：当当前时间间隔内的测量葡萄糖值超过当前时间间隔的目标葡萄糖值时，以及当要施用的推注的葡萄糖降低作用的持续时间跨越当前时间间隔和当前时间间隔的多个时，计算胰岛素推注量的方法下一个相邻的时间间隔可以包括确定推荐的推注剂量的胰岛素作用百分比的相应数量，其将在每个时间间隔的相应时间段内分别使用降低葡萄糖水平，并将推荐的推注量计算为测量的葡萄糖值的功能，下一个相邻时间间隔数量的最后一个的目标血糖水平，当前和下一个相邻时间间隔的数量的胰岛素敏感性以及相应的百分比数。

8. 发明授权

US07553281B2 Insulin bolus recommendation system 有权
标题翻译：胰岛素推注系统
公开(公告)号：US07553281B2
公开(公告)日：2009-06-30
申请号：US11868003
申请日：2007-10-05
申请人： Robert Hellwig , Stefan Weinert
发明人： Robert Hellwig , Stefan Weinert
IPC分类号： A61B5/00 , A61M31/00
CPC分类号： G06F19/3468 , A61M5/1723 , G06F19/00 , G16H10/60 , G16H15/00
摘要： A system for recommending insulin bolus quantities to an insulin user includes a display unit and memory unit coupled to a control circuit with a user blood glucose target stored in the memory unit. The control circuit is programmed to receive the user's current blood glucose value, to determine and display via the display unit a recommended correction insulin bolus quantity if the current blood glucose value exceeds the blood glucose target, to compute a difference value as the current blood glucose value less the blood glucose target, and to produce a modified blood glucose target as a sum of the blood glucose target and the difference value for a lock-out time period if the difference value is positive. Additional correction insulin bolus quantities may be recommended during the lock-out time period if the user's current blood glucose value exceeds the modified blood glucose target.
摘要翻译：用于向胰岛素用户推荐胰岛素推注量的系统包括显示单元和与存储在存储器单元中的用户血糖目标的控制电路耦合的存储单元。控制电路被编程为接收用户的当前血糖值，如果当前血糖值超过血糖目标，则通过显示单元确定和显示推荐的校正胰岛素推注量，以计算当前血糖值如果差值为正值，则减去血糖值，并产生修正的血糖目标作为血糖目标和锁定时间段的差值之和。如果用户的当前血糖值超过修正的血糖目标，则可以在锁定时间段期间推荐额外的校正胰岛素推注量。

9. 发明申请

US20080058628A1 INSULIN BOLUS RECOMMENDATION SYSTEM 有权
标题翻译：胰岛素推荐系统
公开(公告)号：US20080058628A1
公开(公告)日：2008-03-06
申请号：US11868003
申请日：2007-10-05
申请人： Robert Hellwig , Stefan Weinert
发明人： Robert Hellwig , Stefan Weinert
IPC分类号： A61B5/00 , A61M31/00
CPC分类号： G06F19/3468 , A61M5/1723 , G06F19/00 , G16H10/60 , G16H15/00
摘要： A system for recommending insulin bolus quantities to an insulin user includes a display unit and memory unit coupled to a control circuit with a user blood glucose target stored in the memory unit. The control circuit is programmed to receive the user's current blood glucose value, to determine and display via the display unit a recommended correction insulin bolus quantity if the current blood glucose value exceeds the blood glucose target, to compute a difference value as the current blood glucose value less the blood glucose target, and to produce a modified blood glucose target as a sum of the blood glucose target and the difference value for a lock-out time period if the difference value is positive. Additional correction insulin bolus quantities may be recommended during the lock-out time period if the user's current blood glucose value exceeds the modified blood glucose target.
摘要翻译：用于向胰岛素用户推荐胰岛素推注量的系统包括显示单元和与存储在存储器单元中的用户血糖目标的控制电路耦合的存储单元。控制电路被编程为接收用户的当前血糖值，如果当前血糖值超过血糖目标，则通过显示单元确定和显示推荐的校正胰岛素推注量，以计算当前血糖值如果差值为正值，则减去血糖值，并产生修正的血糖目标作为血糖目标和锁定时间段的差值之和。如果用户的当前血糖值超过修正的血糖目标，则可以在锁定时间段期间推荐额外的校正胰岛素推注量。

10. 发明申请

US20120289803A1 SYSTEMS AND METHODS FOR HANDLING UNACCEPTABLE VALUES IN STRUCTURED COLLECTION PROTOCOLS 有权
标题翻译：用于处理结构化收集协议中不可否认值的系统和方法
公开(公告)号：US20120289803A1
公开(公告)日：2012-11-15
申请号：US13107467
申请日：2011-05-13
申请人： Stefan Weinert , Steven Bousamra , David L. Duke , Paul J. Galley , Alan M. Greenburg
发明人： Stefan Weinert , Steven Bousamra , David L. Duke , Paul J. Galley , Alan M. Greenburg
IPC分类号： A61B5/145 , G09B19/00
CPC分类号： G06F19/3456 , G06F19/00 , G16H10/20
摘要： Embodiments of methods of querying a diabetic patient regarding compliance with adherence criteria comprises instructing the diabetic patient to collect at least one sample in a sampling set of biomarker data, wherein each sampling set comprises a sufficient plurality of samples recorded over a collection period, comparing the collected samples to an acceptable range, wherein the acceptable range encompasses biomarker values that would be expected upon compliance with the adherence criteria, and informing the diabetic patient if at least one sample is an unacceptable value which falls outside of the acceptable range, and performing at least one additional task after detecting the unacceptable value.
摘要翻译：查询糖尿病患者关于遵守依从性标准的方法的实施方案包括指示糖尿病患者在生物标志物数据的采样组中收集至少一个样品，其中每个采样组包括在收集期间记录的足够多个样品，收集的样品到可接受的范围，其中可接受的范围包括根据遵守标准预期的生物标志物值，并且通知糖尿病患者，如果至少一个样品是不可接受的值，其不超出可接受的范围，并在在检测到不可接受的数值后再进行一项额外的任务。

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